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Stereoselective synthesis of artemisinin
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“Although artemisinin can be produced by chemical synthesis [171,228,229,230,231,232,233,234,235,236,237,238,239], the structural complexity of this target and the large number of steps involved in all published synthetic routes render this approach far too expensive for many in the Third World who are most affected by malaria.”
From The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao) (2010) · cites this paper as [230]
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Metadata
- Authors
- Ravindranathan, T., Anil Kumar, M., Menon, R. B., & Hiremath, S. V.
- Affiliations
- National Chemical Laboratory (IN)
- Venue
- Tetrahedron Letters
- Publisher
- Elsevier BV
- Published
- 1990-01
- Volume
- 31
- Issue
- 5
- Pages
- 755-758
- ISSN
- 0040-4039 (ISSN-L)
- OpenAlex
- W1984047589
- Cited by
- 103
- References
- 9
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 3 · 2017: 3 · 2016: 2 · 2015: 1 · 2014: 4 · 2013: 4 · 2012: 5
- FWCI
- 2.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Tetrahedron Letters (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Sesquiterpenes and Asteraceae Studies
- Physical Sciences › Chemistry › Organic Chemistry › Organic Chemistry Synthesis Methods
- Physical Sciences › Chemistry › Organic Chemistry › Biological Activity of Diterpenoids and Biflavonoids
- Keywords
- artemisinin, stereoselective synthesis, intramolecular Diels-Alder reaction, trienes, sesquiterpenes, total synthesis
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