Cited by 856Neuroscience and Neural EngineeringTactile and Sensory InteractionsRetinal Development and Disorders

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Visual perception in a blind subject with a chronic microelectronic retinal prosthesis

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Humayun, Mark S., Weiland, James D., Fujii, Gildo Y., Greenberg, Robert, Williamson, Richard, Little, Jim, Mech, Brian, Cimmarusti, Valerie, Van Boemel, Gretchen, Dagnelie, Gislin, de Juan, Eugene·2003·Vision Research

DOI 10.1016/s0042-6989(03)00457-7

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Abstract

A retinal prosthesis was permanently implanted in the eye of a completely blind test subject. This report details the results from the first 10 weeks of testing with the implant subject. The implanted device included an extraocular case to hold electronics, an intraocular electrode array (platinum disks, 4 x 4 arrangement) designed to interface with the retina, and a cable to connect the electronics case to the electrode array. The subject was able to see perceptions of light (spots) on all 16 electrodes of the array. In addition, the subject was able to use a camera to detect the presence or absence of ambient light, to detect motion, and to recognize simple shapes.

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Authors: Humayun, M. S., Weiland, J. D., Fujii, G. Y., Greenberg, R., Williamson, R., Little, J., Mech, B., Cimmarusti, V., Van Boemel, G., Dagnelie, G., & de Juan, E.
Affiliations: University of Southern California (US)
Second Sight Medical Products (US)
Johns Hopkins University (US)
Corresponding author: Humayun, Mark S.
ORCID: Humayun, Mark S.
Weiland, James D.
Dagnelie, Gislin
Venue: Vision Research
Publisher: Elsevier BV
Published: 2003-11
Volume: 43
Issue: 24
Pages: 2573-2581
ISSN: 0042-6989 (ISSN-L)
DOI: 10.1016/s0042-6989(03)00457-7
OpenAlex: W2131773286
Cited by: 856
References: 21
Citations by year: 2026: 11 · 2025: 14 · 2024: 15 · 2023: 13 · 2022: 26 · 2021: 23 · 2020: 20 · 2019: 26 · 2018: 22 · 2017: 32 · 2016: 36 · 2015: 31 · 2014: 46 · 2013: 62 · 2012: 52
FWCI: 15.48
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 3582 d)
Locations: Vision Research (publishedVersion)
PubMed (publishedVersion)
Funders: National Science Foundation
National Eye Institute (R01EY012843)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
Health Sciences › Medicine › Ophthalmology › Retinal Development and Disorders
Keywords: retinal prosthesis, visual perception, platinum electrode, light perception, motion detection, shape recognition, chronic implantation
MeSH terms: Aged, Blindness, Electrodes, Implanted, Humans, Male, Photoreceptor Cells, Retina, Retinitis Pigmentosa, Visual Perception, Treatment Outcome, Prostheses and Implants

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Visual perception in a blind subject with a chronic microelectronic retinal prosthesis

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