The “independent components” of natural scenes are edge filters
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The authors developed a method that accounts for the pitfalls of unbalanced cell-type composition and inflated correlations among sparse genes to call multiresolution gene expression programs from single-cell data using an SVD-based approximation of zero-phase component analysis (ZCA) and gene sparsity-dependent thresholding.
“We developed a method which accounts for these pitfalls to call multiresolution gene expression programs from single-cell data using an SVD-based approximation of zero-phase component analysis (ZCA) and gene sparsity-dependent thresholding99,100.”
From Single-cell multiregion dissection of Alzheimer’s disease (2024) · cites this paper as [100]
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- Authors
- Bell, A. J., & Sejnowski, T. J.
- Venue
- Vision Research
- Publisher
- Elsevier BV
- Published
- 1997-12
- Volume
- 37
- Issue
- 23
- Pages
- 3327-3338
- ISSN
- 0042-6989
- Cited by
- 1,592
- References
- 3
- Language
- en
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