Cited by 203Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology StudiesNeural dynamics and brain function

Two Dimensions of Value: Dopamine Neurons Represent Reward But Not Aversiveness

Fiorillo, Christopher D.·2013·Science

Abstract

Coding Reward Versus Punishment: Reinforcement learning is driven by reward prediction error, and a very influential theory has proposed that dopamine neurons provide this signal to teach value to the brain. Although this is called a reward prediction error, it has been assumed to also represent aversiveness. Thus, it was thought that the dopamine signal could be sufficient for learning total value. Fiorillo (p. 546 ) found that dopamine alone was not sufficient to encode value, implying that there must be an analogous signal for aversiveness.

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Crossref · 10.1126/science.1238699

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  • Recent reports that distinguished between different stimulus components of punishers suggest that the physical impact of punishers is the major determinant for dopamine activations, and the psychophysically assessed aversive nature of the punishers did not explain the recorded dopamine activations.

    “However, recent reports that distinguished between different stimulus components of punishers suggest that the physical impact of punishers is the major determinant for dopamine activations, and the psychophysically assessed aversive nature of the punishers did not explain the recorded dopamine activations25–27.”

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Authors
Fiorillo, C. D.
Affiliations
Korea Advanced Institute of Science and Technology (KR)
Corresponding author
Fiorillo, Christopher D.
Venue
Science
Published
2013-08-02
Volume
341
Issue
6145
Pages
546-549
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2063632085
Cited by
203
References
26
Citations by year
2026: 4 · 2025: 5 · 2024: 31 · 2023: 7 · 2022: 13 · 2021: 10 · 2020: 14 · 2019: 12 · 2018: 15 · 2017: 21 · 2016: 19 · 2015: 20 · 2014: 27 · 2013: 5
FWCI
11.60
Type
journal article
Language
en
Open access
closed
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
Funders
Howard Hughes Medical Institute
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords
dopaminergic neurons, reward, aversiveness, value representation, ventral midbrain, punishment
MeSH terms
Animals, Appetitive Behavior, Conditioning, Classical, Female, Macaca mulatta, Male, Mesencephalon, Punishment, Reward, Dopaminergic Neurons

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