Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis
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PTEN loss of function results in HIF-1α activation by dysregulation of the PI3K/AKT pathway, especially in glioblastoma cells.
“PTEN's loss of function results in HIF-1α activation by dysregulation of the PI3K/AKT pathway, especially in glioblastoma cells [51].”
From Stress Response of Glioblastoma Cells Mediated by miR-17-5p Targeting PTEN and the Passenger Strand miR-17-3p Targeting MDM2 (2012) · cites this paper as [51]
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The phosphoinositide 3-kinase pathway
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Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland
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- Venue
- Advances in Cancer Research
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- Elsevier
- Published
- 2009
- Pages
- 19-65
- ISSN
- 0065-230X
- PMC
- PMC2933405
- Cited by
- 486
- References
- 9
- Language
- en
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