From obesity to cancer: a review on proposed mechanisms
Abstract
Nowadays, obesity is considered as a serious and growing global health problem. It is documented that the overweight and obesity are major risk factors for a series of noncommunicable diseases, and in recent years, the obesity-cancer link has received much attention. Numerous epidemiological studies have shown that obesity is associated with increased risk of several cancer types, including colon, breast, endometrium, liver, kidney, esophagus, gastric, pancreatic, gallbladder, and leukemia, and can also lead to poorer treatment. We review here the epidemiological and experimental evidences for the association between obesity and cancer. Specifically, we discuss potential mechanisms focusing how dysfunctional angiogenesis, chronic inflammation, interaction of proinflammatory cytokines, endocrine hormones, and adipokines including leptin, adiponectin insulin, growth factors, estrogen, and progesterone and strikingly, cell metabolism alteration in obesity participate in tumor development and progression, resistance to chemotherapy, and targeted therapies such as antiangiogenic and immune therapies.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Ectopic fat deposition is related to metabolic abnormalities and defects in insulin sensitivity, T2DM, cardiovascular disease, and cancer.
“Ectopic fat deposition is related to metabolic abnormalities and defects in insulin sensitivity, T2DM, cardiovascular disease, and cancer (143).”
From Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease (2018) · cites this paper as [143]
Cites
1 retracted
Subbaramaiah, K., Morris, P. G., Zhou, X. K., Morrow, M., Du, B., Giri, D. D., Kopelovich, L., Hudis, C. A., & Dannenberg, A. J. (2012) · Cancer Discovery · doi:10.1158/2159-8290.cd-11-0241 · Cited by 244 · see citing works
RetractedUnderstanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Vander Heiden, M. G., Cantley, L. C., & Thompson, C. B. (2009) · Science · doi:10.1126/science.1160809 · Cited by 16,197 · see citing works
Adipose Tissue as an Endocrine Organ
Kershaw, E. E., & Flier, J. S. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0395 · Cited by 5,522 · see citing works
Adipokines in inflammation and metabolic disease
Ouchi, N., Parker, J. L., Lugus, J. J., & Walsh, K. (2011) · Nature Reviews Immunology · doi:10.1038/nri2921 · Cited by 4,625 · see citing works
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
Calle, E. E., & Kaaks, R. (2004) · Nature reviews. Cancer · doi:10.1038/nrc1408 · Cited by 3,613 · see citing works
Central nervous system control of food intake and body weight
Morton, G. J., Cummings, D. E., Baskin, D. G., Barsh, G. S., & Schwartz, M. W. (2006) · Nature · doi:10.1038/nature05026 · Cited by 2,503 · see citing works
Tumor cell metabolism: cancer's Achilles' heel
Kroemer, G., & Pouyssegur, J. (2008) · Cancer Cell · doi:10.1016/j.ccr.2008.05.005 · Cited by 2,337 · see citing works
Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells
Rehman, J., Traktuev, D., Li, J., Merfeld-Clauss, S., Temm-Grove, C. J., Bovenkerk, J. E., Pell, C. L., Johnstone, B. H., Considine, R. V., & March, K. L. (2004) · Circulation · doi:10.1161/01.cir.0000121425.42966.f1 · Cited by 2,269 · see citing works
Cellular Fatty Acid Metabolism and Cancer
Currie, E., Schulze, A., Zechner, R., Walther, T. C., & Farese, R. V. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.05.017 · Cited by 2,123 · see citing works
Overweight, Obesity, and Mortality in a Large Prospective Cohort of Persons 50 to 71 Years Old
Adams, K. F., Schatzkin, A. G., Harris, T. B., Kipnis, V., Mouw, T., Ballard-Barbash, R. R., Hollenbeck, A. R., & Leitzmann, M. F. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa055643 · Cited by 2,115 · see citing works
Nutrition and physical activity guidelines for cancer survivors
Rock, C. L., Doyle, C., Demark‐Wahnefried, W., Meyerhardt, J., Courneya, K. S., Schwartz, A. L., Bandera, E. V., Hamilton, K. K., Grant, B., McCullough, M., et al. (2012) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21142 · Cited by 1,995 · see citing works
Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease
Ouyang, W., Rutz, S., Crellin, N. K., Valdez, P. A., & Hymowitz, S. G. (2011) · Annual Review of Immunology · doi:10.1146/annurev-immunol-031210-101312 · Cited by 1,932 · see citing works
Jung, U. J., & Choi, M. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15046184 · Cited by 1,898 · see citing works
Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
Carmeliet, P., & Jain, R. K. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3455 · Cited by 1,678 · see citing works
Global obesity: trends, risk factors and policy implications
Malik, V., Willett, W. C., & Hu, F. B. (2012) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2012.199 · Cited by 1,418 · see citing works
Targeting cancer metabolism: a therapeutic window opens
Heiden, M. G. V. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3504 · Cited by 1,409 · see citing works
Adipose Tissue Hypoxia in Obesity and Its Impact on Adipocytokine Dysregulation
Hosogai, N., Fukuhara, A., Oshima, K., Miyata, Y., Tanaka, S., Segawa, K., Furukawa, S., Tochino, Y., Komuro, R., Matsuda, M., et al. (2007) · Diabetes · doi:10.2337/db06-0911 · Cited by 1,257 · see citing works
Normalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers
Jain, R. K. (2013) · Journal of Clinical Oncology · doi:10.1200/jco.2012.46.3653 · Cited by 1,248 · see citing works
Parallel progression of primary tumours and metastases
Klein, C. A. (2009) · Nature reviews. Cancer · doi:10.1038/nrc2627 · Cited by 1,134 · see citing works
The economic burden of obesity worldwide: a systematic review of the direct costs of obesity
Withrow, D., & Alter, D. A. (2011) · Obesity Reviews · doi:10.1111/j.1467-789x.2009.00712.x · Cited by 1,083 · see citing works
Adiponectin: More Than Just Another Fat Cell Hormone?
Chandran, M., Phillips, S. A., Ciaraldi, T. P., & Henry, R. R. (2003) · Diabetes Care · doi:10.2337/diacare.26.8.2442 · Cited by 1,007 · see citing works
Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis
Nomura, D. K., Long, J. Z., Niessen, S., Hoover, H. S., Ng, S.-W., & Cravatt, B. F. (2010) · Cell · doi:10.1016/j.cell.2009.11.027 · Cited by 1,002 · see citing works
The Role of the IGF System in Cancer Growth and Metastasis: Overview and Recent Insights
Samani, A. A., Yakar, S., LeRoith, D., & Brodt, P. (2007) · Endocrine Reviews · doi:10.1210/er.2006-0001 · Cited by 999 · see citing works
Sabat, R., Grütz, G., Warszawska, K., Kirsch, S., Witte, E., Wolk, K., & Geginat, J. (2010) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2010.09.002 · Cited by 977 · see citing works
Metformin and Cancer Risk in Diabetic Patients: A Systematic Review and Meta-analysis
DeCensi, A., Puntoni, M., Goodwin, P., Cazzaniga, M., Gennari, A., Bonanni, B., & Gandini, S. (2010) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-10-0157 · Cited by 918 · see citing works
Molecular mechanisms of cancer development in obesity
Khandekar, M. J., Cohen, P., & Spiegelman, B. M. (2011) · Nature reviews. Cancer · doi:10.1038/nrc3174 · Cited by 906 · see citing works
Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue
Halberg, N., Khan, T., Trujillo, M. E., Wernstedt-Asterholm, I., Attie, A. D., Sherwani, S., Wang, Z. V., Landskroner-Eiger, S., Dineen, S., Magalang, U. J., et al. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00192-09 · Cited by 896 · see citing works
TNF-α in promotion and progression of cancer
Balkwill, F. (2006) · Cancer Metastasis Review · doi:10.1007/s10555-006-9005-3 · Cited by 844 · see citing works
A Web Tool for Age–Period–Cohort Analysis of Cancer Incidence and Mortality Rates
Rosenberg, P. S., Check, D. P., & Anderson, W. F. (2014) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-14-0300 · Cited by 825 · see citing works
Obesity and cancer—mechanisms underlying tumour progression and recurrence
Park, J., Morley, T. S., Kim, M. G., Clegg, D. J., & Scherer, P. E. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.94 · Cited by 792 · see citing works
Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development
Baenke, F., Peck, B., Miess, H., & Schulze, A. (2013) · Disease Models & Mechanisms · doi:10.1242/dmm.011338 · Cited by 772 · see citing works
Brahimi-Horn, M. C., Chiche, J., & Pouysségur, J. (2007) · Journal of Molecular Medicine · doi:10.1007/s00109-007-0281-3 · Cited by 765 · see citing works
Popa, C. D., Netea, M. G., van Riel, P. L. C. M., van der Meer, J. W. M., & Stalenhoef, A. F. H. (2007) · Journal of Lipid Research · doi:10.1194/jlr.r600021-jlr200 · Cited by 765 · see citing works
Angiogenesis modulates adipogenesis and obesity
Cao, Y. (2007) · Journal of Clinical Investigation · doi:10.1172/jci32239 · Cited by 736 · see citing works
Bråkenhielm, E., Veitonmäki, N., Cao, R., Kihara, S., Matsuzawa, Y., Zhivotovsky, B., Funahashi, T., & Cao, Y. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308671100 · Cited by 734 · see citing works
Metabolic functions of FABPs—mechanisms and therapeutic implications
Hotamisligil, G. S., & Bernlohr, D. A. (2015) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2015.122 · Cited by 712 · see citing works
Obesity, Hypertension, and the Risk of Kidney Cancer in Men
Chow, W., Gridley, G., Fraumeni, J. F., & Järvholm, B. (2000) · New England Journal of Medicine · doi:10.1056/nejm200011023431804 · Cited by 667 · see citing works
The Role of Adiponectin in Cancer: A Review of Current Evidence
Dalamaga, Μ., Diakopoulos, K. N., & Mantzoros, C. S. (2012) · Endocrine Reviews · doi:10.1210/er.2011-1015 · Cited by 639 · see citing works
Ramagopalan, S. V., Wotton, C. J., Handel, A. E., Yeates, D., & Goldacre, M. J. (2011) · BMC Medicine · doi:10.1186/1741-7015-9-1 · Cited by 632 · see citing works
Targeting the TGFβ pathway for cancer therapy
Neuzillet, C., Tijeras‐Raballand, A., Cohen, R., Cros, J. F., Faivre, S. J., Raymond, É., & Gramont, A. D. E. (2014) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2014.11.001 · Cited by 610 · see citing works
Insulin resistance and cancer risk: An overview of the pathogenetic mechanisms
Arcidiacono, B., Iiritano, S., Nocera, A., Possidente, K., Nevolo, M. T., Ventura, V., Foti, D., Chiefari, E., & Brunetti, A. (2012) · Experimental Diabetes Research · doi:10.1155/2012/789174 · Cited by 606 · see citing works
Physical activity and survival after breast cancer diagnosis: Meta-analysis of published studies
Ibrahim, E. M., & Al-Homaidh, A. (2011) · Medical Oncology · doi:10.1007/s12032-010-9536-x · Cited by 604 · see citing works
Endothelial dysfunction in diabetes mellitus: Molecular mechanisms and clinical implications
Tabit, C. E., Chung, W. B., Hamburg, N. M., & Vita, J. A. (2010) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-010-9134-4 · Cited by 584 · see citing works
Obesity and cancer risk: evidence, mechanisms, and recommendations
Vučenik, I., & Stains, J. P. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2012.06750.x · Cited by 574 · see citing works
Inflammation and Cancer: IL-6 and STAT3 Complete the Link
Bromberg, J., & Wang, T. C. (2009) · Cancer Cell · doi:10.1016/j.ccr.2009.01.009 · Cited by 570 · see citing works
Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage
Grivennikov, S. I., & Karin, M. (2011) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2010.140145 · Cited by 560 · see citing works
Fatty Acid Synthase As a Potential Therapeutic Target in Cancer
Flavin, R., Peluso, S., Nguyen, P. L., & Loda, M. F. (2010) · Future Oncology · doi:10.2217/fon.10.11 · Cited by 545 · see citing works
Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-α
Ruan, H., & Lodish, H. F. (2003) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(03)00052-2 · Cited by 541 · see citing works
Martin, S. S., Qasim, A., & Reilly, M. P. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.05.060 · Cited by 516 · see citing works
Angiogenesis and chronic inflammation: cause or consequence?
Costa, C., Incio, J., & Soares, R. A. (2007) · Angiogenesis · doi:10.1007/s10456-007-9074-0 · Cited by 502 · see citing works
Zaugg, K., Yao, Y., Reilly, P. T., Kannan, K., Kiarash, R., Mason, J. M., Huang, P., Sawyer, S. K., Fuerth, B. J., Faubert, B., et al. (2011) · Genes & Development · doi:10.1101/gad.1987211 · Cited by 493 · see citing works
Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis
(2009) · Advances in Cancer Research · doi:10.1016/s0065-230x(09)02002-8 · Cited by 486 · see citing works
Morris, P. G., Hudis, C. A., Giri, D. D., Morrow, M., Falcone, D. J., Zhou, X. K., Du, B., Brogi, E., Crawford, C. B., Kopelovich, L., et al. (2011) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-11-0110 · Cited by 466 · see citing works
The Regulation of Steroid Action by Sulfation and Desulfation
Mueller, J. W., Gilligan, L. C., Idkowiak, J., Arlt, W., & Foster, P. A. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1036 · Cited by 419 · see citing works
Kubo, A., & Corley, D. A. (2006) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0860 · Cited by 413 · see citing works
Understanding the benefit of metformin use in cancer treatment
Dowling, R. J. O., Goodwin, P. J., & Stambolic, V. (2011) · BMC Medicine · doi:10.1186/1741-7015-9-33 · Cited by 410 · see citing works
Blüher, M., & Mantzoros, C. S. (2014) · Metabolism · doi:10.1016/j.metabol.2014.10.016 · Cited by 399 · see citing works
Sex differences and sex steroids in lung health and disease
Townsend, E. A., Miller, V. M., & Prakash, Y. S. (2012) · Endocrine Reviews · doi:10.1210/er.2010-0031 · Cited by 395 · see citing works
The proliferating role of insulin and insulin-like growth factors in cancer
Gallagher, E. J., & LeRoith, D. (2010) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2010.06.007 · Cited by 391 · see citing works
The dynamic roles of TGF‐β in cancer
Meulmeester, E., & ten Dijke, P. (2010) · The Journal of Pathology · doi:10.1002/path.2785 · Cited by 391 · see citing works
Cancer metabolism: current perspectives and future directions
Muñoz-Pinedo, C., El Mjiyad, N., & Ricci, J.-E. (2012) · Cell Death & Disease · doi:10.1038/cddis.2011.123 · Cited by 385 · see citing works
Wang, Y., Lam, K. S. L., Xu, J. Y., Lü, G., Xu, L. Y., Cooper, G. J. S., & Xu, A. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m501149200 · Cited by 380 · see citing works
Angiogenesis as a Novel Component of Inflammatory Bowel Disease Pathogenesis
Danese, S., Sans, M., de la Motte, C., Graziani, C., West, G. A., Phillips, M. H., Pola, R., Rutella, S., Willis, J., Gasbarrini, A., et al. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.03.054 · Cited by 371 · see citing works
SCHMID, S. M., HALLSCHMID, M., JAUCH‐CHARA, K., BORN, J., & SCHULTES, B. (2008) · Journal of Sleep Research · doi:10.1111/j.1365-2869.2008.00662.x · Cited by 370 · see citing works
The emerging role of adipokines as mediators of inflammation and immune responses
Lago, F., Diéguez, C., Gómez-Reino, J. J., & Gualillo, O. (2007) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2007.04.007 · Cited by 370 · see citing works
Interleukin-6 as a Therapeutic Target
Rossi, J., Lu, Z., Jourdan, M., & Klein, B. (2015) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-14-2291 · Cited by 366 · see citing works
Reflections on the Discovery and Significance of Estrogen Receptor β
Koehler, K. F., Helguero, L. A., Haldosén, L.-A., Warner, M., & Gustafsson, J.-A. (2005) · Endocrine Reviews · doi:10.1210/er.2004-0027 · Cited by 360 · see citing works
Metformin in cancer prevention and therapy.
Kasznicki, J., Śliwińska, A., & Drzewoski, J. (2014) · PubMed Central · doi:10.3978/j.issn.2305-5839.2014.06.01 · Cited by 354 · see citing works
Cruz, P. M. R., Mo, H., McConathy, W. J., Sabnis, N. A., & Lacko, A. G. (2013) · Frontiers in Pharmacology · doi:10.3389/fphar.2013.00119 · Cited by 349 · see citing works
Complexities of TGF-β Targeted Cancer Therapy
Connolly, E. C., Freimuth, J., & Akhurst, R. J. (2012) · International Journal of Biological Sciences · doi:10.7150/ijbs.4564 · Cited by 344 · see citing works
Changes in neuronal activation patterns in response to androgen deprivation therapy: a pilot study
Cherrier, M., Borghesani, P., Shelton, A., & Higano, C. (2010) · BMC Cancer · doi:10.1186/1471-2407-10-1 · Cited by 337 · see citing works
Esophageal and Esophagogastric Junction Cancers
Ajani, J. A., Barthel, J. S., Bentrem, D. J., D’Amico, T. A., Das, P., Denlinger, C. S., Fuchs, C. S., Gerdes, H., Glasgow, R. E., Hayman, J. A., et al. (2011) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2011.0072 · Cited by 331 · see citing works
The Link between the Metabolic Syndrome and Cancer
Braun, S. L., Bitton-Worms, K., & LeRoith, D. (2011) · International Journal of Biological Sciences · doi:10.7150/ijbs.7.1003 · Cited by 326 · see citing works
Induction of leptin resistance through direct interaction of C-reactive protein with leptin
Chen, K., Li, F., Li, J., Cai, H., Strom, S., Bisello, A., Kelley, D. E., Friedman-Einat, M., Skibinski, G. A., McCrory, M. A., et al. (2006) · Nature Medicine · doi:10.1038/nm1372 · Cited by 325 · see citing works
Obesity and cancer risk among white and black United States veterans
Samanic, C. M., Gridley, G., Chow, W., Lubin, J. H., Hoover, R. N., & Fraumeni, J. F. (2004) · Cancer Causes & Control · doi:10.1023/b:caco.0000016573.79453.ba · Cited by 318 · see citing works
Angiogenic Role of LYVE-1–Positive Macrophages in Adipose Tissue
Cho, C.-H., Jun Koh, Y., Han, J., Sung, H.-K., Jong Lee, H., Morisada, T., Schwendener, R. A., Brekken, R. A., Kang, G., Oike, Y., et al. (2007) · Circulation Research · doi:10.1161/01.res.0000259564.92792.93 · Cited by 309 · see citing works
Lipid Catabolism via CPT1 as a Therapeutic Target for Prostate Cancer
Schlaepfer, I. R., Rider, L. C., Rodrigues, L. U., Gijón, M. A., Pac, C. T., Romero, L. M., Cimic, A., Sirintrapun, S. J., Glodé, L. M., Eckel, R. H., et al. (2014) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-14-0183 · Cited by 306 · see citing works
Role of adipokines in cardiovascular disease
Mattu, H. S., & Randeva, H. S. (2012) · Journal of Endocrinology · doi:10.1530/joe-12-0232 · Cited by 292 · see citing works
Adiponectin and cardiovascular health: an update
Hui, X. H., Lam, K. S., Vanhoutte, P. M., & Xu, A. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01395.x · Cited by 287 · see citing works
Metabolic genes in cancer: Their roles in tumor progression and clinical implications
Furuta, E., Okuda, H., Kobayashi, A., & Watabe, K. (2010) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2010.01.005 · Cited by 283 · see citing works
Leal, V. D. O., & Mafra, D. (2013) · Clinica Chimica Acta · doi:10.1016/j.cca.2013.02.003 · Cited by 275 · see citing works
Insulin resistance and cancer: The role of insulin and IGFs
Djiogue, S., Nwabo Kamdje, A. H., Vecchio, L., Kipanyula, M. J., Farahna, M., Aldebasi, Y., & Seke Etet, P. F. (2013) · Endocrine Related Cancer · doi:10.1530/erc-12-0324 · Cited by 263 · see citing works
Prevalence and time trends in obesity among adult West African populations: a meta‐analysis
Abubakari, A. R., Lauder, W., Agyemang, C. O., Jones, M. C., Kirk, A. F., & Bhopal, R. S. (2008) · Obesity Reviews · doi:10.1111/j.1467-789x.2007.00462.x · Cited by 259 · see citing works
Leptin's Role in Lipodystrophic and Nonlipodystrophic Insulin-Resistant and Diabetic Individuals
Moon, H., Dalamaga, Μ., Kim, S. Y., Pοlyzos, S. A., Hamnvik, O. R., Magkos, F., Paruthi, J., & Mantzoros, C. S. (2013) · Endocrine Reviews · doi:10.1210/er.2012-1053 · Cited by 257 · see citing works
Obesity and cancer pathogenesis
Berger, N. A. (2014) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12416 · Cited by 231 · see citing works
Obesity and pancreatic cancer: Overview of epidemiologic evidence and biologic mechanisms
Bracci, P. M. (2011) · Molecular Carcinogenesis · doi:10.1002/mc.20778 · Cited by 230 · see citing works
Progesterone receptors, their isoforms and progesterone regulated transcription
Jacobsen, B. M., & Horwitz, K. B. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.09.016 · Cited by 229 · see citing works
Collaborative Group on Epidemiological Studies of Ovarian Cancer (2012) · PLoS Medicine · doi:10.1371/journal.pmed.1001200 · Cited by 226 · see citing works
Kearns, K., Dee, A., Fitzgerald, T., Doherty, E., & Perry, I. J. (2014) · BMC Public Health · doi:10.1186/1471-2458-14-143 · Cited by 224 · see citing works
Molecular Mechanisms of Tumor Angiogenesis
Ziyad, S., & Iruela‐Arispe, M. L. (2011) · Genes & Cancer · doi:10.1177/1947601911432334 · Cited by 218 · see citing works
Estrogen action and prostate cancer
Nelles, J. L., Hu, W., & Prins, G. S. (2011) · Expert Review of Endocrinology & Metabolism · doi:10.1586/eem.11.20 · Cited by 216 · see citing works
Leptin: molecular mechanisms, systemic pro-inflammatory effects, and clinical implications
Paz-Filho, G., Mastronardi, C. A., Franco, C. B., Wang, K. B., Wong, M., & Licinio, J. (2012) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302012000900001 · Cited by 211 · see citing works
Epithelial ovarian cancer experimental models
Lengyel, E. R., Burdette, J. E., Kenny, H. A., Matei, D. E., Pilrose, J. M., Haluska, P., Nephew, K. P., Hales, D. B., & Stack, M. S. (2013) · Oncogene · doi:10.1038/onc.2013.321 · Cited by 209 · see citing works
Regulation of apoptosis by insulin-like growth factor (IGF)-I
Kooijman, R. (2006) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2006.02.002 · Cited by 201 · see citing works
Kaelin, W. G., & Thompson, C. B. (2010) · Nature · doi:10.1038/465562a · Cited by 198 · see citing works
Intratumoral Estrogens and Estrogen Receptors in Human Non–Small Cell Lung Carcinoma
Niikawa, H., Suzuki, T., Miki, Y., Suzuki, S., Nagasaki, S., Akahira, J., Honma, S., Evans, D. B., Hayashi, S., Kondo, T., et al. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-1950 · Cited by 195 · see citing works
Yang, Y. (2002) · Experimental Cell Research · doi:10.1006/excr.2002.5600 · Cited by 193 · see citing works
The ins and outs of leptin receptor activation
Zabeau, L., Lavens, D., Peelman, F., Eyckerman, S., Vandekerckhove, J. S., & Tavernier, J. H. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)00440-x · Cited by 189 · see citing works
Aballay, L., Eynard, A., Díaz, M. D. P., Navarro, A., & Muñoz, S. E. (2013) · Nutrition reviews · doi:10.1111/j.1753-4887.2012.00533.x · Cited by 187 · see citing works
Lessons from Mouse Models of High-Fat Diet-Induced NAFLD
Nakamura, A., & Terauchi, Y. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms141121240 · Cited by 187 · see citing works
The relevance of the TGF-β Paradox to EMT-MET programs
Morrison, C. D., Parvani, J. G., & Schiemann, W. P. (2013) · Cancer Letters · doi:10.1016/j.canlet.2013.02.048 · Cited by 184 · see citing works
mTOR links oncogenic signaling to tumor cell metabolism
Yecies, J. L., & Manning, B. D. (2011) · Journal of Molecular Medicine · doi:10.1007/s00109-011-0726-6 · Cited by 183 · see citing works
Bonkhoff, H., & Berges, R. R. (2008) · European Urology · doi:10.1016/j.eururo.2008.10.035 · Cited by 183 · see citing works
Interleukin‐6 promotes tumorigenesis by altering DNA methylation in oral cancer cells
Gasche, J. A., Hoffmann, J., Boland, C. R., & Goel, A. (2011) · International Journal of Cancer · doi:10.1002/ijc.25764 · Cited by 178 · see citing works
Metabolic syndrome and risk of cancer: Which link?
Mendonça, F. M., de Sousa, F. R., Barbosa, A. L., Costa-Martins, S., Araújo, R. L., Soares, R. A., & Abreu, C. (2014) · Metabolism · doi:10.1016/j.metabol.2014.10.008 · Cited by 172 · see citing works
Braun, D. A., Fribourg, M., & Sealfon, S. C. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.386573 · Cited by 168 · cited 1× · see citing works
“It binds to its receptor, JAK1 and TYK2 tyrosine kinases phosphorylate, an IL‐10 intracellular domain, and interact with STAT1, STAT3, and STAT5(118) similar to IL‐6, IL‐10 leads to a sustained STAT3 phosphorylation and whereas IL‐6 induces a transient rapidly declining STAT3 phosphorylation and nuclear localization.(…”
BackgroundHursting, S. D., & Dunlap, S. M. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2012.06737.x · Cited by 166 · see citing works
Piva, R., Agnelli, L., Pellegrino, E., Todoerti, K., Grosso, V., Tamagno, I., Fornari, A., Martinoglio, B., Médico, E., Zamò, A., et al. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2008.20.9759 · Cited by 165 · see citing works
The Role of Apelin in Cardiovascular Function and Heart Failure
Chandrasekaran, B., Dar, O., & McDonagh, T. A. (2008) · European Journal of Heart Failure · doi:10.1016/j.ejheart.2008.06.002 · Cited by 163 · see citing works
Mitochondrial Metabolism and Cancer
Weinberg, F. D., & Chandel, N. S. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05039.x · Cited by 162 · see citing works
Tumor angiogenesis—characteristics of tumor endothelial cells
Hida, K., Maishi, N., Torii, C., & Hida, Y. (2016) · International Journal of Clinical Oncology · doi:10.1007/s10147-016-0957-1 · Cited by 156 · see citing works
Targeting AMPK: A new therapeutic opportunity in breast cancer
Hadad, S. M., Fleming, S., & Thompson, A. M. (2008) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2008.01.007 · Cited by 154 · see citing works
Effect of Exercise on Serum Androgens in Postmenopausal Women: A 12-Month Randomized Clinical Trial
McTiernan, A., Tworoger, S. S., Rajan, K. B., Yasui, Y., Sorenson, B., Ulrich, C. M., Chubak, J., Stanczyk, F. Z., Bowen, D. J., Irwin, M. L., et al. (2004) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.1099.13.7 · Cited by 148 · see citing works
Regulation of vascular tone by adipocytes
Maenhaut, N., & de Voorde, J. V. (2011) · BMC Medicine · doi:10.1186/1741-7015-9-25 · Cited by 144 · see citing works
Mechanisms Linking Excess Adiposity and Carcinogenesis Promotion
Pérez-Hernández, A. I., Catalán, V., Gómez‐Ambrosi, J., RodrÃguez, A., & Frühbeck, G. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00065 · Cited by 142 · see citing works
Incio, J., Suboj, P., Chin, S. M., Vardam-Kaur, T., Liu, H., Hato, T., Babykutty, S., Chen, I. X., Deshpande, V., Jain, R. K., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0141392 · Cited by 142 · see citing works
Cao, W., Liu, Y., Zhang, R., Zhang, B., Wang, T., Zhu, X., Mei, L., Chen, H., Zhang, H., Ming, P., et al. (2015) · Scientific Reports · doi:10.1038/srep08477 · Cited by 140 · see citing works
Aikins, A. D., Kushitor, M. K., Koram, K. A., Gyamfi, S., & Ogedegbe, G. G. (2014) · BMC Public Health · doi:10.1186/1471-2458-14-s2-s3 · Cited by 139 · see citing works
Calorie restriction and cancer prevention: a mechanistic perspective
Hursting, S. D., Dunlap, S. M., Ford, N. A., Hursting, M. J., & Lashinger, L. M. (2013) · Cancer & Metabolism · doi:10.1186/2049-3002-1-10 · Cited by 128 · see citing works
Chatterjee, M., Stühmer, T., Herrmann, P., Bommert, K., Dörken, B., & Bargou, R. C. (2004) · Blood · doi:10.1182/blood-2004-04-1670 · Cited by 124 · see citing works
Exogenous fatty acid binding protein 4 promotes human prostate cancer cell progression
Uehara, H., Takahashi, T., Oha, M., Ogawa, H., & Izumi, K. (2014) · International Journal of Cancer · doi:10.1002/ijc.28903 · Cited by 120 · see citing works
Epidemiology and Economic Impact of Obesity and Type 2 Diabetes
Shamseddeen, H. N., Getty, J. L. Z., Hamdallah, I. N., & Ali, M. R. (2011) · Surgical Clinics of North America · doi:10.1016/j.suc.2011.08.001 · Cited by 118 · see citing works
Smad phospho-isoforms direct context-dependent TGF-β signaling
Matsuzaki, K. (2013) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2013.06.002 · Cited by 115 · see citing works
Adipose Tissue and Adipokines: The Association with and Application of Adipokines in Obesity
Khan, M. A., & Joseph, F. (2014) · Scientifica · doi:10.1155/2014/328592 · Cited by 115 · see citing works
The Dual Role of Tumor Necrosis Factor (TNF) in Cancer Biology
Bertazza, L., & Mocellin, S. (2010) · Current Medicinal Chemistry · doi:10.2174/092986710793176339 · Cited by 114 · see citing works
CHOLESTEROL, STATINS AND CANCER
Brown, A. J. (2007) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2007.04565.x · Cited by 112 · see citing works
Macrophages and the Regulation of Adipose Tissue Remodeling
Martinez-Santibañez, G., & Nien-Kai Lumeng, C. (2014) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-071812-161113 · Cited by 111 · see citing works
Adipose Tissue Vascularization: Its Role in Chronic Inflammation
Ye, J. (2011) · Current Diabetes Reports · doi:10.1007/s11892-011-0183-1 · Cited by 109 · see citing works
Nucleotide Metabolism and Cell-Cell Interactions
Eltzschig, H. K., Weissmüller, T., Mager, A., & Eckle, T. D. L. G. (2006) · Humana Press eBooks · doi:10.1385/1-59745-113-4:73 · Cited by 108 · see citing works
TGFβ signaling in head and neck squamous cell carcinoma
White, R. A., Malkoski, S. P., & Wang, X. (2010) · Oncogene · doi:10.1038/onc.2010.306 · Cited by 102 · see citing works
Anti-Inflammatory Effect of Hepatocyte Growth Factor in Chronic Kidney Disease
Gong, R., Rifai, A., & Dworkin, L. D. (2006) · Journal of the American Society of Nephrology · doi:10.1681/asn.2006020185 · Cited by 98 · see citing works
Progesterone and Breast Cancer
Lange, C. A., & Yee, D. (2008) · Women s Health · doi:10.2217/17455057.4.2.151 · Cited by 96 · see citing works
Connective tissue growth factor inhibits adipocyte differentiation
Tan, J. T. M., McLennan, S. V., Song, W. W., Lo, L. W.-Y., Bonner, J. G., Williams, P. F., & Twigg, S. M. (2008) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00333.2007 · Cited by 95 · see citing works
Progesterone and estrogen receptor expression and activity in human non-small cell lung cancer
Márquez‐Garbán, D. C., Mah, V. H., Alavi, M., Maresh, E. L., Chen, H., Bagryanova, L., Horvath, S., Chia, D., Garon, E. B., Goodglick, L., et al. (2011) · Steroids · doi:10.1016/j.steroids.2011.04.015 · Cited by 88 · see citing works
Gati, A., Kouidhi, S., Marrakchi, R., Gaaïed, A. E., Kourda, N., Derouiche, A., Chébil, M., Caignard, A., & Perier, A. (2014) · OncoImmunology · doi:10.4161/onci.27810 · Cited by 85 · see citing works
Qin, Y. W., Fortin, J. S., Tye, D., Gleason-Guzman, M. C., Brooks, T. A., & Hurley, L. H. (2010) · Biochemistry · doi:10.1021/bi100330w · Cited by 80 · see citing works
Estrogenic Regulation of Signaling Pathways and Homeobox Genes During Rat Prostate Development
Huang, L., Pu, Y., Alam, S., Birch, L. A., & Prins, G. S. (2004) · Journal of Andrology · doi:10.1002/j.1939-4640.2004.tb02796.x · Cited by 78 · see citing works
Lee, J. K., So, K. A., Piyathilake, C. J., & Kim, M. K. (2013) · PLoS ONE · doi:10.1371/journal.pone.0066555 · Cited by 72 · see citing works
Human gastric cancer development with TNF-α-inducing protein secreted from Helicobacter pylori
Suganuma, M., Watanabe, T., Yamaguchi, K., Takahashi, A., & Fujiki, H. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.03.027 · Cited by 71 · see citing works
Obesity and Cancer: An Angiogenic and Inflammatory Link
Fukumura, D., Incio, J., Shankaraiah, R. C., & Jain, R. K. (2016) · Microcirculation · doi:10.1111/micc.12270 · Cited by 69 · see citing works
Siltuximab (CNTO 328): a promising option for human malignancies
Chen, B.-A., & Chen, R. (2015) · Drug Design, Development and Therapy · doi:10.2147/dddt.s86438 · Cited by 65 · see citing works
Powell, C. A., Nasser, M. W., Zhao, H., Wochna, J. C., Zhang, X., Shapiro, C. L., Shilo, K., & Ganju, R. K. (2015) · Oncotarget · doi:10.18632/oncotarget.3442 · Cited by 63 · see citing works
Kwong, J., Chan, F. L., Wong, K.-K., Birrer, M. J., Archibald, K. M., Balkwill, F. R., Berkowitz, R. S., & Mok, S. C. (2009) · Neoplasia · doi:10.1593/neo.09112 · Cited by 62 · see citing works
Tumor Necrosis Factor: Renaissance as a Cancer Therapeutic?
Daniel, D., & Wilson, N. S. (2008) · Current Cancer Drug Targets · doi:10.2174/156800908783769346 · Cited by 59 · see citing works
IL-10 promotes resistance to apoptosis and metastatic potential in lung tumor cell lines
Zeng, L., O’Connor, C., Zhang, J., Kaplan, A. M., & Cohen, D. A. (2010) · Cytokine · doi:10.1016/j.cyto.2009.11.015 · Cited by 59 · see citing works
A potential paradox in prostate adenocarcinoma progression: Oestrogen as the initiating driver
Singh, P. B., Matanhelia, S. S., & Martin, F. L. (2008) · European Journal of Cancer · doi:10.1016/j.ejca.2008.02.051 · Cited by 58 · see citing works
Role of LKB1 in lung cancer development
Makowski, L., & Hayes, D. N. (2008) · British Journal of Cancer · doi:10.1038/sj.bjc.6604515 · Cited by 57 · see citing works
Leptin and its cardiovascular effects: Focus on angiogenesis
Khazaei, M., & Tahergorabi, Z. (2015) · Advanced Biomedical Research · doi:10.4103/2277-9175.156526 · Cited by 51 · see citing works
Self-citationBiomarkers of Antiangiogenic Therapy: How Do We Move From Candidate Biomarkers to Valid Biomarkers?
Duda, D. G., Ancukiewicz, M., & Jain, R. K. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2009.24.8021 · Cited by 51 · see citing works
Check, J. H., Dix, E., Cohen, R. L., CHECK, D. L., & Wilson, C. K. (2010) · PubMed · Cited by 51 · see citing works
High Progesterone Receptor Expression in Prostate Cancer Is Associated with Clinical Failure
Grindstad, T., Andersen, S., Al‐Saad, S., Dønnem, T., Kiselev, Y., Melbø‐Jørgensen, C., Skjefstad, K., Busund, L., Bremnes, R. M., & Richardsen, E. H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0116691 · Cited by 49 · see citing works
Vadysirisack, D. D., & Ellisen, L. W. (2011) · Methods in molecular biology · doi:10.1007/978-1-61779-430-8_4 · Cited by 47 · see citing works
The Role of Monoacylglycerol Lipase (MAGL) in the Cancer Progress
Qin, H., & Ruan, Z. (2014) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-014-9899-2 · Cited by 47 · see citing works
The relationship between inflammatory markers, angiogenesis, and obesity.
Tahergorabi, Z., & Khazaei, M. (2013) · Europe PMC (PubMed Central) · Cited by 46 · see citing works
Self-citationSex steroid receptors in human lung diseases
Verma, M. K., Miki, Y., & Sasano, H. (2011) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2011.07.013 · Cited by 46 · see citing works
Unexploited therapies in breast and prostate cancer: blockade of the prolactin receptor
Jacobson, E. M., Hugo, E. R., Tuttle, T. R., Papoian, R., & Ben‐Jonathan, N. (2010) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2010.08.004 · Cited by 43 · see citing works
Diet-Induced Obesity Promotes Colon Tumor Development in Azoxymethane-Treated Mice
Tuominen, I., Alrabadi, L. S., Stavrakis, D. G., Karagiannides, I., Pothoulakis, C., & Bugni, J. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060939 · Cited by 42 · see citing works
Linares, P. M., Chaparro, M., & Gisbert, J. P. (2013) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2013.06.013 · Cited by 38 · see citing works
The involvement of VEGF in endothelial permeability: a target for anti-inflammatory therapy.
Lee, Y. C. (2005) · PubMed · Cited by 38 · see citing works
Li, H., Che, X., Zhao, W., He, S., Zhang, Z., CHEN, R., Fan, L., & Jia, Z. (2013) · Oncology Reports · doi:10.3892/or.2013.2678 · Cited by 37 · see citing works
Shah, J. J., Feng, L., Thomas, S. K., Berkova, Z., Weber, D. M., Wang, M., Qazilbash, M. H., Champlin, R. E., Mendoza, T. R., Cleeland, C., et al. (2016) · Blood Cancer Journal · doi:10.1038/bcj.2016.4 · Cited by 35 · see citing works
Ohri, C. M., Shikotra, A., Green, R. H., Waller, D. A., & Bradding, P. H. (2010) · BMC Cancer · doi:10.1186/1471-2407-10-323 · Cited by 30 · see citing works
Suzuki, K., Ogura, M., Abe, Y., Suzuki, T., Tobinai, K., Ando, K., Taniwaki, M., Maruyama, D., Kojima, M., Kuroda, J., et al. (2015) · International Journal of Hematology · doi:10.1007/s12185-015-1743-y · Cited by 29 · see citing works
Loss of adipocyte specification and necrosis augment tumor-associated inflammation
Wagner, M., Bjerkvig, R., Wiig, H., & Dudley, A. C. (2013) · Adipocyte · doi:10.4161/adip.24472 · Cited by 29 · see citing works
Check, J. H., Dix, E., Wilson, C. K., & CHECK, D. L. (2010) · PubMed · Cited by 27 · see citing works
Minozzi, S., Armaroli, P., Espina, C., Villain, P., Wiseman, M. J., Schüz, J., & Segnan, N. (2015) · Cancer Epidemiology · doi:10.1016/j.canep.2015.08.014 · Cited by 27 · see citing works
Metabolic disturbances linked to obesity: the role of impaired tissue perfusion
Villela, N. R., Kraemer‐Aguiar, L. G., Bottino, D. A., Wiernsperger, N. F., & Bouskela, E. (2009) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302009000200015 · Cited by 25 · see citing works
Aresti, U., Carrera, S., Iruarrizaga, E., Fuente, N., Marrodán, I., de Lobera, A. R., Múñoz, A., Buqué, A., Condori, E., Ugalde, I., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0109659 · Cited by 22 · see citing works
Hajianfar, H., Bahonar, A., Entezari, M. H., Askari, G., & Yazdani, M. (2012) · Europe PMC (PubMed Central) · Cited by 19 · see citing works
Sakamoto, T., Kudoh, T., Sakamoto, K., Matsui, K., & Ogawa, H. (2014) · Hypertension Research · doi:10.1038/hr.2014.22 · Cited by 19 · see citing works
Minireview: The Year in Obesity and Cancer
Hursting, S. D. (2012) · Molecular Endocrinology · doi:10.1210/me.2012-1283 · Cited by 19 · see citing works
Role of anticoagulation in the management of pancreatic cancer.
Sohail, M. A., & Saif, M. W. (2009) · PubMed · Cited by 16 · see citing works
Alasvand, M., Rashidi, B., Javanmard, S. H., Akhavan, M. M., & Khazaei, M. (2015) · Global Journal of Health Science · doi:10.5539/gjhs.v7n7p69 · Cited by 16 · see citing works
Self-citationLi, Y., Chang, J. W. C., Hsieh, L., & Yeh, K. (2010) · Cellular Immunology · doi:10.1016/j.cellimm.2010.07.014 · Cited by 14 · see citing works
Tam, N. N. C., Szeto, C. Y. Y., Freudenberg, J., Fullenkamp, A. N., Medvedovic, M., & Ho, S. (2010) · Molecular Endocrinology · doi:10.1210/me.2010-0179 · Cited by 13 · see citing works
Energy Restriction during Childhood and Early Adulthood and Ovarian Cancer Risk
Schouten, L. J., van Dijk, B. A. C., Lumey, L. H., Goldbohm, R. A., & van den Brandt, P. A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027960 · Cited by 13 · see citing works
Gamma-secretase inhibitor does not modulate angiogenesis in colon adenocarcinoma in obese mice
Khazaei, M., Kalantari, E., Saeidi, H., Shabanikia, N., Tahergorabi, Z., Rashidi, B., Dana, N., & Javanmard, S. H. (2015) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.4149/bll_2015_048 · Cited by 8 · see citing works
Self-citationHu, D.-P., Hu, W., Xie, L., Li, Y., Birch, L. A., & Prins, G. S. (2016) · The Open Biotechnology Journal · doi:10.2174/1874070701610010076 · Cited by 7 · see citing works
Transforming growth factor β type II receptor as a marker in diffuse large B cell lymphoma
Mao, S., Yang, W., Ai, L., Li, Z., & Jin, J. (2015) · Tumor Biology · doi:10.1007/s13277-015-3700-z · Cited by 6 · see citing works
Gender, Sex Hormones and Respiratory Disease
Hemnes, A. R. (2015) · Respiratory medicine · doi:10.1007/978-3-319-23998-9 · Cited by 6 · see citing works
Chaiteerakij, R., Zhen, D. B., Burch, P. A., Chaffee, K. G., Bamlet, W. R., Oberg, A. L., Roberts, L. R., & Petersen, G. M. (2015) · Cancer Research · doi:10.1158/1538-7445.am2015-lb-183 · Cited by 4 · see citing works
Mechanisms Linking Obesity to Cancer Risk
Imayama, I., Mason, C. E., & Duggan, C. R. (2010) · Springer eBooks · doi:10.1007/978-1-4419-7551-5_6 · Cited by 3 · see citing works
Abstract 18: Prohibitin 1 regulates apoptosis via its interaction with XIAP
Xu, Y., Yang, W., Guarani, V., Shi, J., Harper, J. W., & Zetter, B. R. (2015) · Cancer Research · doi:10.1158/1538-7445.am2015-18 · Cited by 3 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease
Smith, R. L., Soeters, M. R., Wüst, R. C. I., & Houtkooper, R. H. (2018) · Endocrine Reviews · doi:10.1210/er.2017-00211 · Cited by 787 · see citing works
Kidney disease and obesity: epidemiology, mechanisms and treatment
Câmara, N. O. S., Iseki, K., Kramer, H., Liu, Z.-H., & Sharma, K. (2017) · Nature Reviews Nephrology · doi:10.1038/nrneph.2016.191 · Cited by 238 · see citing works
Diabetes, Obesity, and Breast Cancer
Kang, C., LeRoith, D., & Gallagher, E. J. (2018) · Endocrinology · doi:10.1210/en.2018-00574 · Cited by 226 · see citing works
Chen, Y., Peng, Q., Yang, Y. J., Zheng, S., Wang, Y., & Lu, W. (2019) · BMC Public Health · doi:10.1186/s12889-019-7633-0 · Cited by 177 · see citing works
Recent advances in biological production of erythritol
Rzechonek, D. A., Dobrowolski, A., Rymowicz, W., & Mirończuk, A. M. (2017) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2017.1380598 · Cited by 174 · see citing works
A Review of the Epidemiology of Breast Cancer in Asia: Focus on Risk Factors
Youn, H. J., & Han, W. (2020) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2020.21.4.867 · Cited by 166 · see citing works
Pancreatic Exocrine Insufficiency in Pancreatic Cancer
Vujasinović, M., Valente, R., Chiaro, M. D., Permert, J., & Löhr, M. J. (2017) · Nutrients · doi:10.3390/nu9030183 · Cited by 145 · see citing works
The Impact of Cereal Grain Composition on the Health and Disease Outcomes
Garutti, M., Nevola, G., Mazzeo, R., Cucciniello, L., Totaro, F., Bertuzzi, C. A., Caccialanza, R., Pedrazzoli, P., & Puglisi, F. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.888974 · Cited by 126 · see citing works
Obesity and prostate cancer: A narrative review
Wilson, R. L., Taaffe, D. R., Newton, R. U., Hart, N. H., Lyons‐Wall, P., & Galvao, D. A. (2021) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2021.103543 · Cited by 109 · see citing works
Amerizadeh, F., Rezaei, N., Rahmani, F., Hassanian, S. M., Moradi‐Marjaneh, R., Fiuji, H., Boroumand, N., Tirkani, A. N., Ghayour‐Mobarhan, M., Ferns, G. A., et al. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.27367 · Cited by 97 · see citing works
Self-citationRetractedAnti-Obesity Effects of Dietary Calcium: The Evidence and Possible Mechanisms
Zhang, F., Ye, J., Zhu, X., Wang, L., Gao, P., Shu, G., Jiang, Q., & Wang, S. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20123072 · Cited by 95 · see citing works
The Impact of the Adipose Organ Plasticity on Inflammation and Cancer Progression
Corrêa, L. H., Cardoso, G. S. H. R., & Magalhães, K. G. (2019) · Cells · doi:10.3390/cells8070662 · Cited by 92 · see citing works
Zeng, H., Ishaq, S. L., Liu, Z., & Bukowski, M. R. (2017) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2017.11.001 · Cited by 70 · see citing works
Li, S., Chen, L., Jin, W., Ma, X., Ma, Y., Dong, F., Zhu, H., Li, J., & Wang, K. (2017) · Scientific Reports · doi:10.1038/s41598-017-18278-x · Cited by 68 · see citing works
Obesity, salivary glands and oral pathology
Roa, I., & del Sol, M. (2018) · Colombia medica · doi:10.25100/cm.v49i4.3919 · Cited by 66 · see citing works
Metabolic syndrome and risk of pancreatic cancer: A population‐based prospective cohort study
Xia, B., He, Q., Pan, Y., Gao, F., Liu, A., Tang, Y., Chong, C. C. N., Teoh, A. Y., Li, F., He, Y., et al. (2020) · International Journal of Cancer · doi:10.1002/ijc.33172 · Cited by 63 · see citing works
Adipocytokines and breast cancer
Li, J., & Han, X. (2018) · Current Problems in Cancer · doi:10.1016/j.currproblcancer.2018.01.004 · Cited by 61 · see citing works
The Emerging Role of Adiponectin in Female Malignancies
Gelsomino, L., Naimo, G. D., Catalano, S., Mauro, L., & Andò, S. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20092127 · Cited by 60 · see citing works
Altered Red Blood Cell Membrane Fatty Acid Profile in Cancer Patients
Amézaga, J., Arranz, S., Urruticoechea, A., Ugartemendia, G., Larraioz, A., Louka, M. A., Uriarte, M., Ferreri, C., & Tueros, I. (2018) · Nutrients · doi:10.3390/nu10121853 · Cited by 59 · see citing works
Pennisi, G., Celsa, C., Giammanco, A., Spatola, F., & Petta, S. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20225613 · Cited by 55 · see citing works
Torres, M. C. P., Bodini, G., Furnari, M., Marabotto, E., Zentilin, P., Strazzabosco, M., & Giannini, E. G. (2020) · Cancers · doi:10.3390/cancers12061422 · Cited by 53 · see citing works
Biomembrane lipids: When physics and chemistry join to shape biological activity
Ramos‐Martín, F., & D’Amelio, N. (2022) · Biochimie · doi:10.1016/j.biochi.2022.07.011 · Cited by 50 · see citing works
Unveiling the Role of Hormonal Imbalance in Breast Cancer Development: A Comprehensive Review
Satpathi, S., Gaurkar, S. S., Potdukhe, A., & Wanjari, M. B. (2023) · Cureus · doi:10.7759/cureus.41737 · Cited by 46 · see citing works
Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages
Wang, Y., Chen, H., Lo, S. J., Chen, Y.-K., Huang, Y.-C., Hu, S. C., Hsieh, Y.-C., Hung, A. C., Hou, M., & Yuan, S. F. (2020) · Cancers · doi:10.3390/cancers12123526 · Cited by 46 · see citing works
Sargolzaei, J., Chamani, E., Kazemi, T., Fallah, S., & Soori, H. (2018) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2018.02.008 · Cited by 44 · see citing works
Self-citationSignaling by Type I Interferons in Immune Cells: Disease Consequences
Ζαννίκου, Μ., Fish, E. N., & Platanias, L. C. (2024) · Cancers · doi:10.3390/cancers16081600 · Cited by 40 · see citing works
Huang, J., Wang, Y., Lo, S. J., Tseng, L., Chen, D., Wu, Y., Hou, M., & Yuan, S. F. (2019) · Cancers · doi:10.3390/cancers12010029 · Cited by 37 · see citing works
Sleep and cancer incidence in Alberta’s Tomorrow Project cohort
McNeil, J., Barberio, A. M., Friedenreich, C. M., & Brenner, D. R. (2018) · SLEEP · doi:10.1093/sleep/zsy252 · Cited by 35 · see citing works
Ghosh, T., Richardson, M. R., Gordon, P. M., Ryder, J. R., Spector, L. G., & Turcotte, L. M. (2020) · Cancer Medicine · doi:10.1002/cam4.3334 · Cited by 34 · see citing works
Zhang, L., Huang, Y., Ling, J., Zhuo, W., Zhen, Y., Shao, M., Luo, Y., & Zhu, Y. (2018) · Cancer Biomarkers · doi:10.3233/cbm-171160 · Cited by 31 · see citing works
Overweight and obesity during adolescence increases the risk of renal cell carcinoma
Landberg, A., Fält, A., Montgomery, S., Sundqvist, P., & Fall, K. (2019) · International Journal of Cancer · doi:10.1002/ijc.32147 · Cited by 30 · see citing works
Understanding pancreatic exocrine insufficiency and replacement therapy in pancreatic cancer
Powell-Brett, S. F., Carino, N. D. L., & Roberts, K. J. (2020) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2020.03.006 · Cited by 29 · see citing works
Campbell, K. L., Landells, C. E., Fan, J., & Brenner, D. R. (2017) · Obesity · doi:10.1002/oby.22010 · Cited by 29 · see citing works
Koriem, K. M. M. (2017) · Asian Pacific Journal of Tropical Biomedicine · doi:10.1016/j.apjtb.2017.09.002 · Cited by 27 · see citing works
Asgharzadeh, F., Bargi, R., Hosseini, M., Farzadnia, M., & Khazaei, M. (2018) · Europe PMC (PubMed Central) · doi:10.22122/arya.v14i2.1550 · Cited by 27 · see citing works
Self-citationBiotechnological production of sweeteners
Hernández-Pérez, A. F., Jofre, F. M., Queiroz, S. D. S., de Arruda, P. V., Chandel, A. K., & Felipe, M. D. G. D. A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-444-64323-0.00009-6 · Cited by 27 · see citing works
Association of metabolic health phenotypes, obesity, and hepatocellular carcinoma risk
Nasereldin, D. S., White, L. J., Hodge, D. O., Roberts, L. R., Patel, T. C., & Antwi, S. O. (2021) · Digestive and Liver Disease · doi:10.1016/j.dld.2021.12.002 · Cited by 26 · see citing works
Adipose Tissue Metabolism and Cancer Progression: Novel Insights from Gut Microbiota?
Jordan, B. F., Gourgue, F., & Cani, P. D. (2017) · Current Pathobiology Reports · doi:10.1007/s40139-017-0154-6 · Cited by 25 · see citing works
Long Non-Coding RNAs in Obesity-Induced Cancer
Yau, M. Y. C., Xu, L., Huang, C., & Wong, C. (2018) · Non-Coding RNA · doi:10.3390/ncrna4030019 · Cited by 25 · see citing works
Xia, B., Peng, J., Toni, E. N. D., Lu, K., Cheung, E. C., Kuo, Z., He, Q., Tang, Y., Liu, A., Fan, D., et al. (2021) · BMC Cancer · doi:10.1186/s12885-021-08760-1 · Cited by 23 · see citing works
Sammarraie, S. H. A. A., Ayaz‐Güner, Ş., Acar, M. B., Şimşek, A., Sınıksaran, B. S., Bozalan, H. D., Özkan, M., Saraymen, R., Dündar, M., & Özcan, S. (2024) · Scientific Reports · doi:10.1038/s41598-024-70127-w · Cited by 23 · see citing works
Prior joint disease is associated with increased risk of periarticular histiocytic sarcoma in dogs
Manor, E., Craig, L. E., Sun, X., & Cannon, C. M. (2017) · Veterinary and Comparative Oncology · doi:10.1111/vco.12338 · Cited by 21 · see citing works
Thomson, C. A., Crane, T. E., Garcia, D. O., Wertheim, B. C., Hingle, M. D., Snetselaar, L. G., Datta, M., Rohan, T. E., LeBlanc, E. S., Chlebowski, R. T., et al. (2017) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2017.06.010 · Cited by 20 · see citing works
Ang, J.-H. C., Sun, L., Foo, S.-Y. R., Leow, M. K., Vidal‐Puig, A., Fontana, L., & Dalakoti, M. (2025) · Cell Reports Medicine · doi:10.1016/j.xcrm.2025.102354 · Cited by 21 · see citing works
Signaling Targets Related to Antiobesity Effects of Capsaicin: A Scoping Review
Ávila, D. L., Nunes, N. A. M., Almeida, P. H. R. F., Gomes, J. D. A. S., Rosa, C. D. O. B., & Alvarez-Leite, J. I. (2021) · Advances in Nutrition · doi:10.1093/advances/nmab064 · Cited by 19 · see citing works
Yang, X., Tang, W., Mao, D., Liu, X., Qian, W., Dai, Y., Chen, L., & Ding, X. (2022) · BMC Public Health · doi:10.1186/s12889-022-14293-4 · Cited by 18 · see citing works
Exploring the mechanism of Pueraria lobata (Willd.) Ohwi in the regulation of obesity
Mao, J., Li, M., Wang, X., Wang, B., Luo, P., Wang, B., & Guo, X. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118703 · Cited by 18 · see citing works
Mitochondrial uncoupler SHC517 reverses obesity in mice without affecting food intake
Chen, S.-Y., Beretta, M., Alexopoulos, S. J., Shah, D. P., Olzomer, E. M., Hargett, S. R., Childress, E. S., Salamoun, J. M., Aleksovska, I., Roseblade, A., et al. (2021) · Metabolism · doi:10.1016/j.metabol.2021.154724 · Cited by 18 · see citing works
Delaye, M., Rousseau, A., Mailly-Giacchetti, L., Assoun, S., Sokol, H., & Neuzillet, C. (2023) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2023.108442 · Cited by 17 · see citing works
Moodi, M., Tavakoli, T., & Tahergorabi, Z. (2021) · International Journal of Preventive Medicine · doi:10.4103/ijpvm.ijpvm_266_20 · Cited by 17 · see citing works
Self-citationTakenaga, K., Akimoto, M., Koshikawa, N., & Nagase, H. (2021) · Scientific Reports · doi:10.1038/s41598-021-82617-2 · Cited by 16 · see citing works
Crosstalk between obesity and cancer: a role for adipokines
Tahergorabi, Z., Lotfi, H., Rezaei, M., Aftabi, M., & Moodi, M. (2021) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2021.1988110 · Cited by 16 · see citing works
Self-citationIdentification of oncogenic signatures in the inflammatory colon of C57BL/6 mice fed a high-fat diet
Zeng, H., Safratowich, B. D., Cheng, W., & Bukowski, M. R. (2022) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2022.109188 · Cited by 15 · see citing works
Alternative for natural sweeteners: Improving the use of stevia as a source of steviol glycosides
de Andrade, M. V. S., Lucho, S. R., de Castro, R. D., & ribeiro, P. R. R. (2023) · Industrial Crops and Products · doi:10.1016/j.indcrop.2023.117801 · Cited by 20 · see citing works
Type I Interferons as Joint Regulators of Tumor Growth and Obesity
Gessani, S., & Belardelli, F. (2021) · Cancers · doi:10.3390/cancers13020196 · Cited by 15 · see citing works
ADIPOQ rs2241766 SNP as protective marker against DIBC development in Mexican population
Macías‐Gómez, N. M., Hernández-Terrones, M. C., Ramírez-Guerrero, A. A., Leal‐Ugarte, E., Angulo, M. G., & Peregrina-Sandoval, J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0214080 · Cited by 15 · see citing works
Modak, S., Aktar, T., Majumder, D., Singha, A. K., & Maiti, D. (2025) · Genes and Immunity · doi:10.1038/s41435-025-00333-7 · Cited by 14 · see citing works
Emerging potential of whey proteins in prevention of cancer
Ramani, A., Hazra, T., Mudgil, S., & Mudgil, D. (2023) · Food and Humanity · doi:10.1016/j.foohum.2023.12.007 · Cited by 13 · see citing works
Zhuang, S., Jian, Y., & Sun, Y. (2017) · World Journal of Gastroenterology · doi:10.3748/wjg.v23.i23.4233 · Cited by 13 · see citing works
Veronda, A. C., & Irish, L. A. (2020) · Chronobiology International · doi:10.1080/07420528.2020.1861000 · Cited by 12 · see citing works
Fonnegra, C. B., Funes, D. A. R., Valera, R. J., Gómez, C. O., Menzo, E. L., Szomstein, S., & Rosenthal, R. J. (2021) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2021.08.012 · Cited by 13 · see citing works
Mozafarizadeh, M., Omran, S. P., Kordestani, Z., Manshadi, H. R. D., Faridazar, A., & Houshmand, M. (2019) · PubMed Central · doi:10.30498/ijb.2019.99594 · Cited by 12 · see citing works
Quantitative analysis of peri-tumor fat in different molecular subtypes of breast cancer
Chen, J., Zhang, Y., Chan, S., Chang, R., & Su, M. (2018) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2018.06.019 · Cited by 11 · see citing works
Yao, X. X., Luo, X.-Y., Tai, Y., Wang, K., & Shang, J.-W. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1358017 · Cited by 10 · see citing works
Zhang, B., Guo, M., Lü, Y., Zeng, Y., & Jiang, J. (2025) · Cancer Medicine · doi:10.1002/cam4.71030 · Cited by 11 · see citing works
Soy Food Intake and Pancreatic Cancer Risk: The Japan Public Health Center–based Prospective Study
Yamagiwa, Y., Sawada, N., Shimazu, T., Yamaji, T., Goto, A., Takachi, R., Ishihara, J., Iwasaki, M., Inoue, M., & Tsugane, S. (2020) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-19-1254 · Cited by 9 · see citing works
Dwivedi, J., Wal, P., Dash, B., Ovais, M., Sachan, P., & Verma, V. (2023) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/0118715303265960230926113201 · Cited by 8 · see citing works
Polymorphism analysis of ADIPOQ gene in Greek patients with diabetic retinopathy
Gouliopoulos, N., Siasos, G., Bouratzis, N., Oikonomou, E. K., Kollia, C., Κόνσολα, Θ., Oikonomou, D., ROUVAS, A. A., Kassi, E. N., Tousoulis, D. M., et al. (2021) · Ophthalmic Genetics · doi:10.1080/13816810.2021.2015787 · Cited by 8 · see citing works
Liu, D., Yang, J., & Wang, S. (2021) · Public Health · doi:10.1016/j.puhe.2021.11.014 · Cited by 8 · see citing works
Prevalence, Consequences, Causes and Management of Obesity
Tappia, P. S., & Defries, D. M. (2020) · Springer eBooks · doi:10.1007/978-3-030-35358-2_1 · Cited by 8 · see citing works
Let-7a-5p Regulates Animal Lipid Accumulation by Targeting Srebf2 and Thbs1 Signaling
Shao, J., Jiang, G., Li, Y., Wang, M., Tang, T., Wang, J., Jia, X., & Lai, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25020894 · Cited by 7 · see citing works
Leptin and adiponectin dynamics at patients with rectal neoplasm - Gender differences
Florescu, A., Brǎnişteanu, D. D. D., Bilhă, Ş., Scripcariu, D. V., Florescu, I., Scripcariu, V., Dimofte, G., & Grigoraș, I. (2019) · PLoS ONE · doi:10.1371/journal.pone.0212471 · Cited by 6 · see citing works
Role of adipocyte browning in prostate and breast tumor microenvironment
Ku, H., & Cheng, C. (2022) · Tzu Chi Medical Journal · doi:10.4103/tcmj.tcmj_62_22 · Cited by 5 · see citing works
Recent Perspectives on Meat Consumption and Cancer Proliferation
Momal, U., Naeem, H., Aslam, F., Shahbaz, M., Imran, M. A., Hussain, M., Ahmad, A., Memon, A. G., Mujtaba, A., Atif, M., et al. (2025) · Journal of Food Processing and Preservation · doi:10.1155/jfpp/6567543 · Cited by 7 · see citing works
Obesity: A Prerequisite for Major Chronic Illnesses
Afolabi, H. A., Zakarıa, Z., Salleh, M. S. M., Ch’ng, E. S., Nafi, S. N. M., Aziz, A. A. A., Al-Mhanna, S. B., Irekeola, A. A., Wada, Y., & Daku, A. B. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.111935 · Cited by 5 · see citing works
Li, J., Tang, Y., Lu, G., Liu, Q., Guo, Y., Wang, J., Xiao, M., Gao, T., Zhang, X., & Gu, J. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.07.014 · Cited by 4 · see citing works
Toorang, F., Amiri, P., Pouraram, H., & Takian, A. (2025) · BMC Public Health · doi:10.1186/s12889-024-21221-1 · Cited by 5 · see citing works
Wojtyła-Buciora, P., Bołdowski, T., Wojtyła, C., Żukiewicz-Sobczak, W., Wojtyła, K., Chęcińska-Maciejewska, Z., Wojtyła, A., & Krauss, H. (2016) · Journal of Health Inequalities · doi:10.5114/jhi.2016.65359 · Cited by 4 · see citing works
Wojtyła-Buciora, P., Bołdowski, T., Wojtyła, C., Żukiewicz-Sobczak, W., Juszczak, K., Łabędzka-Gardy, M., Wojtyła, A., & Krauss, H. (2017) · Journal of Health Inequalities · doi:10.5114/jhi.2017.69169 · Cited by 4 · see citing works
Obesity and Inflammation Lead to Insulin Resistance and Cancer—A Systematic Review
Hossen, M. S., Barek, M. A., & Islam, M. S. (2024) · Springer eBooks · doi:10.1007/978-3-031-62491-9_3 · Cited by 3 · see citing works
Resistant starch inhibits high-fat diet-induced oncogenic responses in the colon of C57BL/6 mice
Zeng, H., Safratowich, B. D., Liu, Z., & Bukowski, M. R. (2025) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2025.109838 · Cited by 2 · see citing works
Chou, C.-L., Lin, C.-W., Li, W., Chen, T.-J., Lee, S., Tian, Y., Kuo, Y., Tsai, H.-H., Wu, L.-C., Yeh, C.-F., et al. (2025) · OncoTargets and Therapy · doi:10.2147/ott.s488608 · Cited by 2 · see citing works
A review of novel methods of reducing oil absorption in fried food products
Tahergorabi, R., Ansarifar, E., Moodi, M., & Tahergorabi, Z. (2024) · Sālnāmah va āmār. · doi:10.61186/jbums.31.2.113 · Cited by 2 · see citing works
Self-citationSharifi, L. (2019) · Springer eBooks · doi:10.1007/978-3-030-16073-9_13 · Cited by 2 · see citing works
Dietary energy density and risk of prostate cancer: (A case–control study)
Jalilpiran, Y., Mehranfar, S., Jafari, A., Mohajeri, S. A. R., & Faghih, S. (2021) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2021.03.028 · Cited by 2 · see citing works
Obesity, diabetes mellitus and oncopathology: epidemiological and pathogenetic aspects
Чернышов, В. А. (2018) · Ukrainian Therapeutical Journal · doi:10.30978/utj2018-3-4-86 · Cited by 2 · see citing works
Castro, N., Silva, L. B. A. R., & Ong, T. P. (2019) · Royal Society of Chemistry eBooks · doi:10.1039/9781788016506-00147 · Cited by 2 · see citing works
Relationship between the main components of metabolic syndrome and oral diseases
Sharonova, L. A., Bulgakova, S. V., Burakshaev, S. A., Dolgikh, Y. A., Kosareva, O. V., Treneva, E. V., Kurmaev, D. P., & Merzlova, P. Y. (2025) · Экспериментальная и клиническая гастроэнтерология · doi:10.31146/1682-8658-ecg-228-8-131-142 · Cited by 1 · see citing works
Wali, S. S. (2026) · International Journal of General Medicine · doi:10.2147/ijgm.s604182 · Cited by 1 · see citing works
Cancer types with high numbers of driver events are largely preventable
Belikov, A. V., & Leonov, S. V. (2022) · PeerJ · doi:10.7717/peerj.12672 · Cited by 1 · see citing works
Cedano-Prieto, D. M., Bergez‐Hernández, F., Leal-León, E., García‐Magallanes, N., Luque‐Ortega, F., Picos-Cárdenas, V. J., Guerrero-Arambula, E., Gutiérrez-Zepeda, B. M., Romo-Martínez, E. J., & Arámbula‐Meraz, E. (2022) · Journal of Oncology · doi:10.1155/2022/7398444 · Cited by 1 · see citing works
Luaran Hasil Leukemia Mieloid Akut yang Menjalani Terapi pada Ruang Kemoterapi Semi-Isolasi
Irawan, C., Steven, R., Gunarsa, R. G., & Tenggara, J. B. (2022) · Jurnal Penyakit Dalam Indonesia · doi:10.7454/jpdi.v9i3.857 · Cited by 1 · see citing works
Role of Vitamin D in the diagnosis of acute Myeloid Leukemia
Tahir, N. T., Thamer, N. A., & Mahmood, N. A. (2023) · Bionatura · doi:10.21931/rb/2023.08.01.50 · Cited by 1 · see citing works
Ciocîrlan, M. (2017) · Endoscopy International Open · doi:10.1055/s-0043-102937 · Cited by 1 · see citing works
Diagnosis and Management of Pancreatic Exocrine Insufficiency in Pancreatic Cancer
Powell-Brett, S. F., & Roberts, K. J. (2021) · doi:10.1002/9781119570097.ch66 · Cited by 1 · see citing works
Cancer In Women: Risk Factors and Prevention
Dobrila-Dintinjana, R., Redžović, A., & Dintinjana, M. (2017) · Womens Health International
Variations of Adipokine Profile in Patients Diagnosed with Rectal Carcinoma
Florescu, A. (2019) · Acta Endocrinologica (Bucharest) · doi:10.4183/aeb.2019.407
Anthropogenic risk factors as the major cause of cancer driver eventsPreprint
Belikov, A. V. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/486860
Obesitateak minbizia izateko arriskua handitzen du... Zer mekanismo daude tartean?
Zorita, S., Trepiana, J., Eseberri, I., & Portillo, M. P. (2020) · EKAIA Euskal Herriko Unibertsitateko Zientzi eta Teknologi Aldizkaria · doi:10.1387/ekaia.21604
Effect of calcium supplementation on weight loss in overweight and obese women, Baghdad, 2021
Jasim, A. H., Ali, B. M., & Abbas, B. G. (2022) · International Journal of Health Sciences · doi:10.53730/ijhs.v6ns2.8978
- Authors
- Tahergorabi, Z., Khazaei, M., Moodi, M., & Chamani, E.
- Affiliations
- Birjand University of Medical Sciences (IR)
- Mashhad University of Medical Sciences (IR)
- Corresponding author
- Chamani, Elham
- Venue
- Cell Biochemistry and Function
- Publisher
- Wiley
- Published
- 2016-11-09
- Volume
- 34
- Issue
- 8
- Pages
- 533-545
- ISSN
- 0263-6484 (ISSN-L)
- 1099-0844
- OpenAlex
- W2564261821
- Cited by
- 118
- References
- 183
- Citations by year
- 2026: 7 · 2025: 11 · 2024: 11 · 2023: 9 · 2022: 12 · 2021: 16 · 2020: 10 · 2019: 14 · 2018: 13 · 2017: 14 · 2016: 1
- FWCI
- 1.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cell Biochemistry and Function (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Cancer Risks and Factors
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer, Lipids, and Metabolism
- Keywords
- obesity, cancer risk, colon cancer, breast cancer, endometrial cancer, liver cancer, esophageal cancer, gastric cancer, pancreatic cancer, gallbladder cancer, leukemia, chronic inflammation, angiogenesis, inflammatory cytokines, endocrine hormones, adipokines, leptin, adiponectin, insulin, estrogen, progesterone, cancer metabolism, chemoresistance, anti-angiogenic therapy, immunotherapy
- MeSH terms
- Animals, Disease Models, Animal, Humans, Models, Biological, Neoplasms, Obesity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review