Depressive Characteristics of FSL Rats
Abstract
Antidepressant effects of acute or chronic nicotine treatments in swim test immobility of Flinders sensitive line (FSL) rats, an animal model of depression, were recently demonstrated (Tizabi et al. Psychopharmacology 142:193, 1999). In the present study we sought to determine whether the antidepressant effects of nicotine could be blocked by the nicotinic antagonist, mecamylamine (MEC). Moreover, the effects of chronic nicotine treatment on [3H]cytisine binding in discrete brain regions of FSL and their control Flinders resistant line (FRL) rats were also evaluated. Adult male FSL rats were treated with MEC (0.5 mg/kg) 20 min prior to an acute or chronic nicotine administration. MEC by itself did not affect the immobility in swim test. However, it completely blocked the acute or chronic nicotine effects. Daily nicotine injection (0.4 mg/kg/day for 14 days) resulted in an increase in [3H]cytisine binding primarily in the FRL rats. An increase in nicotinic receptor binding following chronic nicotine administration is believed to reflect desensitization of these receptors. These findings, coupled with previous observation of higher basal nicotinic receptors in FSL rats, further support the involvement of central nicotinic receptors in depressive characteristics of these rats. Moreover, the data suggest therapeutic potential for selective nicotinic receptor agonists in depressive disorders.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Activation of nAChRs decreases depression-like behavior in the Flinders-sensitive rat model.
“suggesting that activation of nAChRs de-creases depression-like behavior in this model (Tizabi et al. 2000)”
From Mechanisms of Nicotine Addiction (2021) · cites this paper as Tizabi et al. 2000
Acute nicotine administration is antidepressant-like in the forced swim test in Flinders-sensitive rats.
“acute nicotine administration is antidepressant-like in the forced swim test”
From Mechanisms of Nicotine Addiction (2021) · cites this paper as Tizabi et al. 2000
The antidepressant-like effect of acute nicotine in Flinders-sensitive rats can be blocked by mecamylamine.
“this effect can be blocked by the nicotinic antagonist mecamylamine”
From Mechanisms of Nicotine Addiction (2021) · cites this paper as Tizabi et al. 2000
Mecamylamine can block the ability of nicotine to be effective in some models of antidepressant efficacy in selectively bred rats.
“the nicotinic antagonist mecamylamine can block the ability of nicotine to be effective in some models of antidepressant efficacy in selectively bred rats (Tizabi et al., 2000).”
From It is not “either/or”: Activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood (2008) · cites this paper as Tizabi et al., 2000
Mecamylamine can have antidepressant-like properties in mouse models, but antidepressant effects of this drug are not observed in assays of rats.
“while the nicotinic antagonist mecamylamine can have antidepressant-like properties in mouse models (Picciotto et al., 2008; Picciotto et al., 2012), antidepressant effects of this drug are not observed in assays of rats (Tizabi et al., 2000)”
From Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states (2015) · cites this paper as Tizabi et al., 2000
Abnormal nicotinic signaling may underlie depression symptoms.
“These results indicate that abnormal nicotinic signaling may underlie depression symptoms (Mineur et al., 2013; Tizabi et al., 2000)”
From Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states (2015) · cites this paper as Tizabi et al., 2000
Cites
Presynaptic nicotinic ACh receptors
Wonnacott, S. (1997) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)10073-4 · Cited by 1,308 · see citing works
Clarke, P. B. S., Schwartz, R., Paul, S. M., Cb, P., & Pert, A. (1985) · Journal of Neuroscience · doi:10.1523/jneurosci.05-05-01307.1985 · Cited by 1,037 · see citing works
Flores, C. M., Rogers, S. W., Pabreza, L. A., Wolfe, B. B., & Kellar, K. J. (1992) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)08832-7 · Cited by 880 · see citing works
Lucki, I. (1997) · Behavioural Pharmacology · doi:10.1097/00008877-199711000-00010 · Cited by 803 · see citing works
Smoking and Major Depression: A Causal Analysis
Kendler, K. S. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820130038007 · Cited by 792 · see citing works
Cigarette smoking: implications for psychiatric illness
(1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.4.546 · Cited by 723 · see citing works
Major Depression and Stages of Smoking
Breslau, N., Peterson, E. L., Schultz, L. R., Chilcoat, H. D., & Andreski, P. M. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.2.161 · Cited by 639 · see citing works
The Flinders sensitive line rats: a genetic animal model of depression
Overstreet, D. H. (1993) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80230-1 · Cited by 369 · see citing works
Self-citationThe paradox of nicotinic acetylcholine receptor upregulation by nicotine
Wonnacott, S. (1990) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(90)90242-z · Cited by 357 · see citing works
Brain nicotinic receptors: structure and regulation, role in learning and reinforcement
Changeux, J.-P., Bertrand, D., Corringer, P.-J., Dehaene, S., Edelstein, S., Léna, C., Le Novère, N., Marubio, L., Picciotto, M., & Zoli, M. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00040-4 · Cited by 322 · see citing works
[3H]cytisine binding to nicotinic cholinergic receptors in brain.
Pabreza, L. A., Dhawan, S., & Kellar, K. J. (1991) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)10925-5 · Cited by 264 · see citing works
Major depression following smoking cessation
(1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.2.263 · Cited by 250 · see citing works
Vizi, E. S., & Lendvai, B. (1999) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00016-8 · Cited by 228 · see citing works
Schizophrenia and Nicotinic Receptors
Freedman, R., Adler, L. E., Bickford, P. C., Byerley, W., Coon, H. H., Cullum, C. M., Griffith, J. M., Harris, J. G., Leonard, S. S., Miller, C. L., et al. (1994) · Harvard Review of Psychiatry · doi:10.3109/10673229409017136 · Cited by 217 · see citing works
Antidepressant effects of nicotine in an animal model of depression
Tizabi, Y., Overstreet, D. H., Rezvani, A. H., Louis, V. A., Clark Jr, E., Janowsky, D. S., & Kling, M. A. (1999) · Psychopharmacology · doi:10.1007/s002130050879 · Cited by 209 · see citing works
Self-citationDownregulation of nicotinic receptor function after chronic nicotine infusion.
Marks, M. J., Grady, S. R., & Collins, A. C. (1993) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)39368-7 · Cited by 190 · see citing works
Olale, F., Gerzanich, V., Kuryatov, A., Wang, F., & Lindstrom, J. M. (1997) · PubMed · Cited by 172 · see citing works
Overstreet, D. H., Puciłowski, O., Rezvani, A. H., & Janowsky, D. S. (1995) · Psychopharmacology · doi:10.1007/bf02245589 · Cited by 161 · see citing works
Self-citationNicotinic Receptor Function in the Mammalian Central Nervous Systema
Albuquerque, E. X., Pereira, E. F. R., Castro, N. G., Alkondon, M., Reinhardt, S., Schröder, H., & Maelicke, A. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb17464.x · Cited by 156 · see citing works
Antidepressantlike effects of chronic nicotine on learned helplessness paradigm in rats
Semba, J., Mataki, C., Yamada, S., Nankai, M., & Toru, M. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(97)00477-0 · Cited by 140 · see citing works
Lü, Y., Grady, S. R., Marks, M. J., Picciotto, M. R., Changeux, J., & Collins, A. C. (1998) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37839-5 · Cited by 129 · see citing works
Effects of transderman nicotine on mood and sleep in nonsmoking major depresssed patients
Salín-Pascual, R. J., Galicia-Polo, L., Drucker-Colín, R., de la Fuente, J. R., Drucker-Colín, R., & Salín-Pascual, R. J. (1995) · Psychopharmacology · doi:10.1007/bf02246496 · Cited by 113 · see citing works
Barrantes, G. E., Rogers, A. T., Lindstrom, J. M., & Wonnacott, S. (1995) · Brain Research · doi:10.1016/0006-8993(94)01386-v · Cited by 106 · see citing works
A novel effect of nicotine on mood and sleep in major depression
Salín-Pascual, R. J., & Drucker-Colı́n, R. (1998) · Neuroreport · doi:10.1097/00001756-199801050-00012 · Cited by 106 · see citing works
Heterogeneity and Regulation of Nicotinic Acetylcholine Receptors
Lukas, R. J., & Bencherif, M. (1992) · International review of neurobiology · doi:10.1016/s0074-7742(08)60097-5 · Cited by 96 · see citing works
Antidepressant Effect of Ingested Nicotine in Female Rats of Flinders Resistant and Sensitive Lines
Djurić, V. J., Dunn, E., Overstreet, D. H., Dragomir, A., & Steiner, M. (1999) · Physiology & Behavior · doi:10.1016/s0031-9384(99)00091-8 · Cited by 79 · see citing works
Self-citationDesensitization of central cholinergic mechanisms and neuroadaptation to nicotine
Ochoa, E. L. M., Li, L., & McNamee, M. G. (1990) · Molecular Neurobiology · doi:10.1007/bf02780343 · Cited by 77 · see citing works
Puciłowski, O., & Overstreet, D. H. (1993) · Brain Research Bulletin · doi:10.1016/0361-9230(93)90293-k · Cited by 72 · see citing works
Self-citationImmobility-reducing effects of antidepressants in a genetic animal model of depression
Schiller, G. D., Puciłowski, O., Wienicke, C., & Overstreet, D. H. (1992) · Brain Research Bulletin · doi:10.1016/0361-9230(92)90267-2 · Cited by 70 · see citing works
Self-citationNicotinic Receptors and Cholinergic Neurotransmission in the Central Nervous System
Clarke, P. B. S. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb17465.x · Cited by 22 · see citing works
Conti‐Fine, B. M., Maelicke, A., Reinhardt-Maelicke, S., Chiappinelli, V. A., & McLane, K. E. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb17470.x · Cited by 10 · see citing works
Determinants of nicotine self-administration
Shoaib, M. C. (1996) · Drug Development Research · doi:10.1002/(sici)1098-2299(199607/08)38:3/4 · Cited by 7 · see citing works
Flagged first, then by citations
3 of the 35 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
D, M. F. M., & Kendler, K. S. (2000) · Neuron · doi:10.1016/s0896-6273(00)00112-4 · Cited by 619 · see citing works
Effect of nicotine and nicotinic receptors on anxiety and depression
Picciotto, M. R., Brunzell, D. H., & Caldarone, B. J. (2002) · Neuroreport · doi:10.1097/00001756-200207020-00006 · Cited by 483 · see citing works
PICCIOTTO, M., ADDY, N., MINEUR, Y., & BRUNZELL, D. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.12.005 · Cited by 451 · see citing works
The validity of animal models of predisposition to depression
Willner, P., & Mitchell, P. J. (2002) · Behavioural Pharmacology · doi:10.1097/00008877-200205000-00001 · Cited by 430 · see citing works
The Flinders Sensitive Line rat: A selectively bred putative animal model of depression
Overstreet, D. H., Friedman, E. M., Mathé, A. A., & Yadid, G. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.03.015 · Cited by 375 · see citing works
Self-citationNicotinic acetylcholine receptors as targets for antidepressants
Shytle, R. D., Silver, A. A., Lukas, R. J., Newman, M. B., Sheehan, D. V., & Sanberg, P. R. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001035 · Cited by 279 · see citing works
Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis
Mineur, Y. S., & Picciotto, M. R. (2010) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2010.09.004 · Cited by 277 · see citing works
Neuroinflammation, Neurodegeneration, and Depression
Hurley, L. L., & Tizabi, Y. (2012) · Neurotoxicity Research · doi:10.1007/s12640-012-9348-1 · Cited by 260 · see citing works
Self-citationSmoking, nicotine and neuropsychiatric disorders
Döme, P., Lazáry, J., Kalapos, M. P., & Rihmer, Z. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.07.013 · Cited by 215 · see citing works
Effects of Nicotine in Experimental Animals and Humans: An Update on Addictive Properties
Foll, B. L., & Goldberg, S. R. (2009) · Handbook of experimental pharmacology · doi:10.1007/978-3-540-69248-5_12 · Cited by 194 · see citing works
Molecular Mechanisms Underlying Behaviors Related to Nicotine AddictionPreprint
Picciotto, M. R., & Kenny, P. J. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a012112 · Cited by 178 · see citing works
Major Depression: One Brain, One Disease, One Set of Intertwined Processes
Filatova, E. V., Shadrina, M. I., & Slominsky, P. A. (2021) · Cells · doi:10.3390/cells10061283 · Cited by 167 · see citing works
Picciotto, M. R., Lewis, A. S., van Schalkwyk, G. I., & Mineur, Y. S. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.12.028 · Cited by 157 · see citing works
Mechanisms of Nicotine Addiction
Picciotto, M. R., & Kenny, P. J. (2021) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a039610 · Cited by 157 · see citing works
Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction
Mineur, Y. S., & Picciotto, M. R. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.06.010 · Cited by 138 · see citing works
Nicotine as a typical drug of abuse in experimental animals and humans
Foll, B. L., & Goldberg, S. R. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0155-8 · Cited by 131 · see citing works
Overstreet, D. H. (2002) · Behavior Genetics · doi:10.1023/a:1020262205227 · Cited by 122 · see citing works
Self-citationMolecules and circuits involved in nicotine addiction: The many faces of smoking
Picciotto, M. R., & Mineur, Y. S. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.04.028 · Cited by 117 · see citing works
Ruszkiewicz, J. A., Zhang, Z., Gonçalves, F. M., Tizabi, Y., Zelikoff, J. T., & Aschner, M. (2020) · Food and Chemical Toxicology · doi:10.1016/j.fct.2020.111245 · Cited by 118 · see citing works
Self-citationLinks Between Depression and Substance Abuse in Adolescents
Rao, U. (2006) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2006.07.002 · Cited by 101 · see citing works
Andreasen, J., Olsen, G., Wiborg, O., & Redrobe, J. (2009) · Journal of Psychopharmacology · doi:10.1177/0269881108091587 · Cited by 101 · see citing works
Vázquez-Palacios, G., Bonilla‐Jaime, H., & Velázquez‐Moctezuma, J. (2004) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2004.03.002 · Cited by 89 · see citing works
Andreasen, J. T., & Redrobe, J. P. (2009) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e32832c713e · Cited by 82 · see citing works
Kroes, R. A., Burgdorf, J. S., Otto, N. J., Panksepp, J., & Moskal, J. R. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.03.022 · Cited by 80 · see citing works
Positive and Negative Effects of Alcohol and Nicotine and Their Interactions: A Mechanistic Review
Hurley, L. L., Taylor, R. E., & Tizabi, Y. (2011) · Neurotoxicity Research · doi:10.1007/s12640-011-9275-6 · Cited by 79 · see citing works
Self-citationPopik, P., Kozela, E., & Krawczyk, M. (2003) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0705359 · Cited by 74 · see citing works
Animal Models of Depressive Illness: The Importance of Chronic Drug Treatment
Mitchell, P. B., & Redfern, P. H. (2005) · Current Pharmaceutical Design · doi:10.2174/1381612053382250 · Cited by 73 · see citing works
Alcohol Induced Depressive-Like Behavior is Associated with a Reduction in Hippocampal BDNF
Hauser, S. R., Getachew, B., Taylor, R., & Tizabi, Y. (2011) · Pharmacology, Biochemistry and Behavior · doi:10.1016/j.pbb.2011.08.014 · Cited by 74 · see citing works
Self-citationMineur, Y. S., Mose, T. N., Blakeman, S., & Picciotto, M. R. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13769 · Cited by 71 · see citing works
Shang, X., Shang, Y., Fu, J., & Zhang, T. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0012-2 · Cited by 69 · see citing works
Chau, D. T., Rada, P. V., Kosloff, R. A., Taylor, J. L., & Hoebel, B. G. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00133-6 · Cited by 66 · see citing works
Effects of nicotine on depressive-like behavior and hippocampal volume of female WKY rats
Tizabi, Y., Hauser, S. R., Tyler, K. Y., Getachew, B., Madani, R., Sharma, Y., & Manaye, K. F. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.09.024 · Cited by 63 · see citing works
Self-citationAn automated analysis of rat behavior in the forced swim test
Hédou, G., Pryce, C. R., Iorio, L. D., Heidbreder, C. A., & Feldon, J. (2001) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00575-5 · Cited by 58 · see citing works
Tizabi, Y., Louis, V. A., Taylor, C. T., Waxman, D., Culver, K. E., & Szechtman, H. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01207-0 · Cited by 56 · see citing works
Self-citationPotential therapeutic uses of mecamylamine and its stereoisomers
Nickell, J. R., Grinevich, V. P., Siripurapu, K. B., Smith, A. M., & Dwoskin, L. P. (2013) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.04.005 · Cited by 52 · see citing works
Duality of Antidepressants and Neuroprotectants
Tizabi, Y. (2015) · Neurotoxicity Research · doi:10.1007/s12640-015-9577-1 · Cited by 47 · see citing works
Self-citationAndreasen, J. T., & Redrobe, J. P. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.08.016 · Cited by 47 · see citing works
Caldarone, B. J., Wang, D., Paterson, N. E., Manzano, M., Fedolak, A., Cavino, K., Kwan, M., Hanania, T., Chellappan, S. K., Kozikowski, A. P., et al. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2271-y · Cited by 47 · see citing works
Russig, H. D., Pezze, M. A., Bahr, N. I., Pryce, C. R., Feldon, J., & Murphy, C. A. (2003) · Behavioural Pharmacology · doi:10.1097/00008877-200302000-00001 · Cited by 45 · see citing works
Viveros, M., Marco, E. M., Llorente, R., & Lamota, L. (2007) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e3282d28fb4 · Cited by 44 · see citing works
Antidepressant-like action of nicotine in forced swimming test and brain serotonin in mice
Suemaru, K., YASUDA, K., Cui, R., LI, B., Umeda, K., Amano, M., MITSUHASHI, H., TAKEUCHI, N., Inoue, T., & Gomita, Y. (2006) · Physiology & Behavior · doi:10.1016/j.physbeh.2006.05.007 · Cited by 44 · see citing works
Tizabi, Y., Getachew, B., Rezvani, A. H., Hauser, S. R., & Overstreet, D. H. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2008.09.010 · Cited by 42 · see citing works
Self-citationAndreasen, J. T., Nielsen, E. Ø., Christensen, J. K., Olsen, G. M., Peters, D., Mirza, N. R., & Redrobe, J. P. (2010) · Journal of Psychopharmacology · doi:10.1177/0269881110364271 · Cited by 38 · see citing works
Padley, J. R., Overstreet, D. H., Pilowsky, P. M., & Goodchild, A. K. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00430.2005 · Cited by 36 · see citing works
Self-citationThe Periaqueductal Gray and Its Extended Participation in Drug Addiction Phenomena
Vázquez-León, P., Miranda-Páez, A., Chávez‐Reyes, J., Allende, G., Barragán‐Iglesias, P., & Marichal‐Cancino, B. A. (2021) · Neuroscience Bulletin · doi:10.1007/s12264-021-00756-y · Cited by 33 · see citing works
Yamada, M., Kawahara, Y., Kaneko, F., Kishikawa, Y., Sotogaku, N., Poppinga, W. J., Folgering, J. H. A., Dremencov, E., Kawahara, H., & Nishi, A. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.04.044 · Cited by 31 · see citing works
The co-occurrence of smoking and a major depressive episode among mothers 15 months after delivery
Whitaker, R. C., Orzol, S. M., & Kahn, R. S. (2007) · Preventive Medicine · doi:10.1016/j.ypmed.2007.07.005 · Cited by 24 · see citing works
Levin, E. D., Tizabi, Y., Rezvani, A. H., Caldwell, D. P., Petro, A. E., & Getachew, B. (2005) · Brain Research · doi:10.1016/j.brainres.2005.01.104 · Cited by 26 · see citing works
Self-citationNovel targets for parkinsonism-depression comorbidity
Tizabi, Y., Getachew, B., Csoka, A. B., Manaye, K. F., & Copeland, R. (2019) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2019.06.004 · Cited by 25 · see citing works
Self-citationNicotine and 17β-estradiol produce an antidepressant-like effect in female ovariectomized rats
Kandi, P., & Hayslett, R. L. (2010) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2010.12.012 · Cited by 24 · see citing works
Rao, U., & Chen, L.-A. (2008) · Current Drug Abuse Reviews · doi:10.2174/1874473710801010068 · Cited by 22 · see citing works
Cholinergic receptor subtypes in the olfactory bulbectomy model of depression
Slotkin, T. A., & Seidler, F. J. (2005) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2005.09.005 · Cited by 22 · see citing works
Andreasen, J. T., Nielsen, E. Ø., & Redrobe, J. P. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1560-1 · Cited by 21 · see citing works
Nicotine and nicotinic system in hypoglutamatergic models of schizophrenia
Tizabi, Y. (2007) · Neurotoxicity Research · doi:10.1007/bf03033907 · Cited by 21 · see citing works
Self-citationTayyab, M., Shahi, M. H., Farheen, S., M., M. M. P., Khanam, N., & Hossain, M. S. (2019) · Heliyon · doi:10.1016/j.heliyon.2019.e01600 · Cited by 18 · see citing works
Nicotinic Receptor Intervention in Parkinson's Disease: Future Directions.
Tizabi, Y., & Getachew, B. (2017) · PubMed · Cited by 19 · see citing works
Self-citationCzubak, A., Nowakowska, E., Gołembiowska, K., Kus, K., Burda, K., & Metelska, J. (2010) · PubMed · Cited by 17 · see citing works
Getachew, B., Hauser, S. R., Csoka, A. B., Taylor, R. E., & Tizabi, Y. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.03.004 · Cited by 15 · see citing works
Self-citationChronic nicotine administration does not alter cognitive or mood associated behavioural parameters
Ijomone, O. M., Olaibi, O. K., Mba, C., Biose, I. J., Tete, S. A., & Nwoha, P. U. (2015) · Pathophysiology · doi:10.1016/j.pathophys.2014.12.004 · Cited by 14 · see citing works
Weinberger, A. H., McKee, S. A., Picciotto, M. R., & Mazure, C. M. (2010) · Journal of Psychopharmacology · doi:10.1177/0269881110389347 · Cited by 14 · see citing works
Xia, W., Veljkovic, E., Koshibu, K., Peitsch, M. C., & Hoeng, J. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.172809 · Cited by 13 · see citing works
Roles of N-Acylethanolamines in Brain Functions and Neuropsychiatric Diseases
Pistis, M., & Muntoni, A. L. (2017) · Springer eBooks · doi:10.1007/978-3-319-57371-7_11 · Cited by 12 · see citing works
Smethells, J. R., Burroughs, D., Saykao, A. T., Pentel, P. R., Rezvani, A. H., & LeSage, M. G. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108433 · Cited by 10 · see citing works
Self-citationKhadrawy, Y. A., El-Shamy, K. A., & Mohamed, S. (2011) · PubMed · Cited by 9 · see citing works
Kang, H.-K., Kang, M.-A., Kim, H., Park, Y.-S., Kim, S. H., & Kang, J.-S. (2014) · Translational and Clinical Pharmacology · doi:10.12793/tcp.2014.22.1.35 · Cited by 8 · see citing works
Mesripour, A., Soltani, L., & Aliomrani, M. (2023) · Toxicology Research · doi:10.1093/toxres/tfad126 · Cited by 4 · see citing works
Sternberg, Z. (2015) · NeuroMolecular Medicine · doi:10.1007/s12017-015-8375-5 · Cited by 4 · see citing works
Steyn, S. F. (2011) · Boloka Institutional Repository (North-west University) · Cited by 3 · see citing works
Effects of Smoking on Hormones, Brain, and Behavior
Sidhartha, T., Poland, R. E., & Rao, U. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00108-x · Cited by 2 · see citing works
Kang, H.-K., Kang, M.-A., Park, Y.-S., Kim, S., & Kang, J.-S. (2014)
- Authors
- Tizabi, Y., Rezvani, A. H., Russell, L. T., Tyler, K. Y., & Overstreet, D. H.
- Affiliations
- Howard University (US)
- University of North Carolina at Chapel Hill (US)
- Corresponding author
- Tizabi, Yousef
- Venue
- Pharmacology Biochemistry and Behavior
- Publisher
- Elsevier BV
- Published
- 2000-05
- Volume
- 66
- Issue
- 1
- Pages
- 73-77
- ISSN
- 0091-3057 (ISSN-L)
- OpenAlex
- W183627304
- Cited by
- 70
- References
- 35
- Citations by year
- 2023: 1 · 2021: 2 · 2020: 3 · 2019: 3 · 2017: 4 · 2016: 1 · 2015: 4 · 2014: 2 · 2013: 3 · 2012: 2
- FWCI
- 1.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pharmacology Biochemistry and Behavior (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- Flinders Sensitive Line rats, depression, nicotine, mecamylamine, nicotinic acetylcholine receptors, chronic nicotine treatment, receptor desensitization, antidepressant effects, nicotinic agonists, animal models of depression
- MeSH terms
- Quinolizidine Alkaloids, Alkaloids, Animals, Antidepressive Agents, Azocines, Depression, Male, Mecamylamine, Nicotine, Quinolizines, Receptors, Nicotinic, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
