p53, the Cellular Gatekeeper for Growth and Division

WAF1, a potential mediator of p53 tumor suppression

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, C. A., Butel, J. S., & Bradley, A. (1992) · Nature · doi:10.1038/356215a0 · Cited by 4,649

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Toshiyuki, M., & Reed, J. C. (1995) · Cell · doi:10.1016/0092-8674(95)90412-3 · Cited by 4,063

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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p53 is required for radiation-induced apoptosis in mouse thymocytes

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Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations

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p53: puzzle and paradigm.Preprint

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

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Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation Domain

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LMP1 of Epstein–Barr virus suppresses cellular senescence associated with the inhibition of p16INK4a expression

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Molecular Responses to Photogenotoxic Stress Induced by the Antibiotic Lomefloxacin in Human Skin Cells: From DNA Damage to Apoptosis

Marrot, L., Belaïdi, J. P., Jones, C., Perez, P., Meunier, J. R., Riou, L., & Sarasin, A. (2003) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2003.12422.x · Cited by 70

Computerized Video Time-Lapse Microscopy Studies of Ionizing Radiation-Induced Rapid-Interphase and Mitosis-Related Apoptosis in Lymphoid Cells

Endlich, B., Radford, I. R., Forrester, H. B., & Dewey, W. C. (2000) · Radiation Research · doi:10.1667/0033-7587(2000)153[0036:cvtlms]2.0.co;2 · Cited by 66

Identification and Characterization of the Cytoplasmic Protein TRAF4 as a p53-regulated Proapoptotic Gene

Sax, J. K., & El-Deiry, W. S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303191200 · Cited by 60

Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy

Zhang, Z., Ding, Q., Liu, J.-J., Zhang, J., Jiang, N., Chu, X.-J., Bartkovitz, D., Luk, K.-C., Janson, C., Tovar, C., et al. (2014) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2014.05.072 · Cited by 60

p16INK4a modulates p53 in primary human mammary epithelial cells.

Zhang, J., Pickering, C. R., Holst, C. R., Gauthier, M. L., & Tlsty, T. D. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-1594 · Cited by 60

Oxidative stress in cultured cerebral endothelial cells induces chromosomal aberrations, micronuclei, and apoptosis

Bresgen, N., Karlhuber, G., Krizbai, I., Bauer, H., Bauer, H. C., & Eckl, P. M. (2003) · Journal of Neuroscience Research · doi:10.1002/jnr.10582 · Cited by 58

p53-dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene

Wang, S.-J., Yu, G., Jiang, L., Li, T., Lin, Q., Tang, Y., & Gu, W. (2013) · Cell Cycle · doi:10.4161/cc.23597 · Cited by 54

Elucidation of Acquired Resistance to Bcl-2 and MDM2 Inhibitors in Acute Leukemia In Vitro and In Vivo

Hoffman-Luca, C. G., Ziazadeh, D., McEachern, D., Zhao, Y., Sun, W., Debussche, L., & Wang, S. (2015) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-14-2506 · Cited by 52

Double-Edged Swords as Cancer Therapeutics: Novel, Orally Active, Small Molecules Simultaneously Inhibit p53–MDM2 Interaction and the NF-κB Pathway

Zhuang, C., Miao, Z., Wu, Y., Guo, Z., Li, J., Yao, J., Xing, C., Sheng, C., & Zhang, W. (2014) · Journal of Medicinal Chemistry · doi:10.1021/jm401800k · Cited by 50

Cooperativity of p19ARF, Mdm2, and p53 in murine tumorigenesis

Moore, L., Venkatachalam, S., Vogel, H., Watt, J. C., Wu, C.-L., Steinman, H., Jones, S. N., & Donehower, L. A. (2003) · Oncogene · doi:10.1038/sj.onc.1206985 · Cited by 48

Activation of the Fanconi Anemia/BRCA Pathway and Recombination Repair in the Cellular Response to Solar Ultraviolet Light

Dunn, J., Potter, M., Rees, A., & Rünger, T. M. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-0563 · Cited by 42

Structural and Functional Comparison of the RING Domains of Two p53 E3 Ligases, Mdm2 and Pirh2

Shloush, J., Vlassov, J. E., Engson, I., Duan, S., Saridakis, V., Dhe-paganon, S., Raught, B., Sheng, Y., & Arrowsmith, C. H. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.157669 · Cited by 42

MdmX inhibits Smad transactivation

Kadakia, M., Brown, T. L., McGorry, M. M., & Berberich, S. J. (2002) · Oncogene · doi:10.1038/sj.onc.1205993 · Cited by 39

Synthesizing a Genetic Sensor Based on CRISPR-Cas9 for Specifically Killing p53-Deficient Cancer Cells

Zhan, H., Xie, H., Zhou, Q., Liu, Y., & Huang, W. (2018) · ACS Synthetic Biology · doi:10.1021/acssynbio.8b00202 · Cited by 36

Initial Testing (Stage 1) of MK‐8242—A Novel MDM2 Inhibitor—by the Pediatric Preclinical Testing Program

Kang, M. H., Reynolds, C. P., Kolb, E. A., Gorlick, R., Carol, H., Lock, R., Keir, S. T., Maris, J. M., Wu, J., Lyalin, D., et al. (2016) · Pediatric Blood & Cancer · doi:10.1002/pbc.26064 · Cited by 36

Widespread Overexpression of Epitope-Tagged Mdm4 Does Not Accelerate Tumor Formation In Vivo

De Clercq, S., Gembarska, A., Denecker, G., Maetens, M., Naessens, M., Haigh, K., Haigh, J. J., & Marine, J.-C. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00330-10 · Cited by 35

Essential Role of Phospholipase Cγ2 in Early B-Cell Development and Myc-Mediated Lymphomagenesis

Wen, R., Chen, Y., Bai, L., Fu, G., Schuman, J., Dai, X., Zeng, H., Yang, C., Stephan, R. P., Cleveland, J. L., et al. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00839-06 · Cited by 34

Cytoplasmic tethering is involved in synergistic inhibition of p53 by Mdmx and Mdm2

Ohtsubo, C., Shiokawa, D., Kodama, M., Gaiddon, C., Nakagama, H., Jochemsen, A. G., Taya, Y., & Okamoto, K. (2009) · Cancer Science · doi:10.1111/j.1349-7006.2009.01180.x · Cited by 32

Role of histone acetyltransferases MOF and Tip60 in genome stability

Mir, U. S., Bhat, A., Mushtaq, A., Pandita, S., Altaf, M., & Pandita, T. K. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103205 · Cited by 32

The effect of financial development on economic Growth: Evidence from south Asian developing countries

Bibi, R., & Sumaira (2022) · Journal of Environmental Science and Economics · doi:10.56556/jescae.v1i1.1 · Cited by 30

A Tumor-specific MicroRNA Recognition System Facilitates the Accurate Targeting to Tumor Cells by Magnetic Nanoparticles

Yu, Y., Yao, Y., Yan, H., Wang, R., Zhang, Z., Sun, X., Zhao, L., Ao, X., Xie, Z., & Wu, Q. (2016) · Molecular Therapy - Nucleic Acids · doi:10.1038/mtna.2016.28 · Cited by 31

Enhancement of UVB-induced DNA damage repair after a chronic low-dose UVB pre-stimulation

Drigeard Desgarnier, M.-C., & Rochette, P. J. (2018) · DNA Repair · doi:10.1016/j.dnarep.2018.01.008 · Cited by 24

A wide-ranging cellular response to UV damage of DNA

Stokes, M., & Comb, M. (2008) · Cell Cycle · doi:10.4161/cc.7.14.6326 · Cited by 21

Ascorbic acid extends replicative life span of human embryonic fibroblast by reducing DNA and mitochondrial damages

Hwang, W.-S., Park, S.-H., Kim, H.-S., Kang, H.-J., Kim, M.-J., Oh, S.-J., Park, J.-B., Kim, J., Kim, S. C., & Lee, J.-Y. (2007) · Nutrition Research and Practice · doi:10.4162/nrp.2007.1.2.105 · Cited by 21

A Multinucleating Escherichia Coli Cytotoxin Perturbs Cell Cycle in Cultured Epithelial Cells

Giamboi-Miraglia, A., Travaglione, S., Filippini, P., Fabbri, A., Fiorentini, C., & Falzano, L. (2007) · Toxicology in Vitro · doi:10.1016/j.tiv.2006.08.013 · Cited by 19

HMG-CoA Reductase Inhibitor Statins Activate the Transcriptional Activity of p53 by Regulating the Expression of TAZ

Miyajima, C., Hayakawa, Y., Inoue, Y., Nagasaka, M., & Hayashi, H. (2022) · Pharmaceuticals · doi:10.3390/ph15081015 · Cited by 17

Hitting on the move: targeting intrinsically disordered protein states of the MDM2-p53 interaction

Neochoritis, C. G., Atmaj, J., Twarda-Clapa, A., Surmiak, E., Skalniak, L., Köhler, L.-M., Muszak, D., Kurpiewska, K., Kalinowska-Tłuścik, J., Beck, B., et al. (2019) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2019.111588 · Cited by 12

Determination of cellular uptake and intracellular levels of Cenersen (Aezea®, EL625), a p53 antisense oligonucleotide in acute myeloid leukemia cells

Alachkar, H., Xie, Z., Marcucci, G., & Chan, K. K. (2012) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2012.08.011 · Cited by 11

ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ

Атабекова, Б. Б. (2024) · Habaršy. Pedagogika ġylymdary seriâsy · doi:10.51889/2959-5762.2023.80.4.019

Modified straight division: A computer implementation of multiple-precision division

Parthasarathi, R., & Jhunjhunwala, A. (1995) · Microprocessing and Microprogramming · doi:10.1016/0165-6074(94)00091-n · Cited by 1

Καινοτόμες τεχνολογικές εφαρμογές για άτομα με αναπηρία στο τμήμα δωματίων (Rooms Division) των ελληνικών ξενοδοχείων

Θεοχάρης, Ν. (2020) · doi:10.12681/eadd/47729

Climatic Division of Kantô District, Japan

Yoshino, M. M. (1967) · Annals of the Tohoku Geographical Association · doi:10.5190/tga1948.19.165 · Cited by 1

APA Division 47: Division 47 Presidents

(2012) · PsycEXTRA Dataset · doi:10.1037/e672072012-001