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The burden and costs of chronic diseases in low-income and middle-income countries.
Abstract
This paper estimates the disease burden and loss of economic output associated with chronic diseases-mainly cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes-in 23 selected countries which account for around 80% of the total burden of chronic disease mortality in developing countries. In these 23 selected low-income and middle-income countries, chronic diseases were responsible for 50% of the total disease burden in 2005. For 15 of the selected countries where death registration data are available, the estimated age-standardised death rates for chronic diseases in 2005 were 54% higher for men and 86% higher for women than those for men and women in high-income countries. If nothing is done to reduce the risk of chronic diseases, an estimated US$84 billion of economic production will be lost from heart disease, stroke, and diabetes alone in these 23 countries between 2006 and 2015. Achievement of a global goal for chronic disease prevention and control-an additional 2% yearly reduction in chronic disease death rates over the next 10 years-would avert 24 million deaths in these countries, and would save an estimated $8 billion, which is almost 10% of the projected loss in national income over the next 10 years.
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“Epidemiological transitions are defined by a shift from a heavy burden of infectious diseases to a major prevalence of noncommunicable diseases (NCDs)”
From Colonial transition as a major mediator of global health transition: lessons from the 2024 New Caledonia crisis (2025) · cites this paper as [3]
In the citing paper
“which currently account for about 80% of all deaths worldwide”
From Colonial transition as a major mediator of global health transition: lessons from the 2024 New Caledonia crisis (2025) · cites this paper as [3]
In the citing paper
“and are thus closely connected to the ageing of the populations – i.e. the demographic transition [3]”
From Colonial transition as a major mediator of global health transition: lessons from the 2024 New Caledonia crisis (2025) · cites this paper as [3]
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Polymorphism in the CLOCK gene may influence the effect of fat intake reduction on weight loss
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“The presence of NCDs accounted for 80 % of the total disease mortality burden in developing countries, with an estimated $84 billion of economic production lost due to heart disease, stroke, and diabetes alone [4].”
BackgroundBelizán, M., Alonso, J. P., Nejamis, A., Caporale, J., Copo, M. G., Sanchez, M. A., Rubinstein, A., & Irazola, V. E. (2019) · Translational Behavioral Medicine · doi:10.1093/tbm/ibz040 · Cited by 31
“Nearly half of the deaths in those countries are individuals under 70 years old, whereas only 27 per cent of the same age group die in high-income countries [2].”
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“Hypertension (HT) and diabetes mellitus (DM) are important public health challenges worldwide, and together, contribute significantly to mortality through cardiac, cerebral and renal events (Abegunde et al. 2007).”
BackgroundDoenças crônicas Não transmissíveis e o suporte das ações intersetoriais no seu enfrentamento
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“In common with other LMICs, Indonesia is facing a double burden of disease from both communicable and noncommunicable chronic diseases.(3)”
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“Chronic diseases are deadlier in developing countries than in industrialized ones, and the discrepancy is even greater for women than men [3].”
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“It calculated the economic burden for 2005 and predicted a prognosis of burden for 2015 and 2030 of the most prevalent noncommunicable diseases from a macroeconomic perspective based on death rate [3].”
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“The importance of non-communicable diseases – and especially of cardiovascular related morbidity and mortality [3,4] – is rising steeply in low-income countries, unmasking new unmet needs for risk assessment and early diagnosis [5].”
BackgroundCapítulo 14 – Crise Hipertensiva
Malachias, M. V. B., Souza, W., Plavnik, F. L., Rodrigues, C., Brandão, A., Neves, M. F., Bortolotto, L. A., Franco, R., Figueiredo, C., Jardim, P., et al. (2016) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.20160164 · Cited by 32
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“Economic status may influence health literacy, access to care, and burden of chronic conditions and it is possible that these factors impact the burden of dry eye among Central and South American populations [55].”
BackgroundThe Economic Costs of Noncommunicable Diseases in the Pacific Islands
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Alcohol use, drunkenness and tobacco smoking in rural western K enya
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Why a Macroeconomic Perspective Is Critical to the Prevention of Noncommunicable Disease
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Wahl, A. K., Osborne, R. H., Langeland, E., Wentzel‐Larsen, T., Mengshoel, A. M., Ribu, L., Peersen, K., Elsworth, G. R., & Nolte, S. (2016) · Patient Education and Counseling · doi:10.1016/j.pec.2016.05.001 · Cited by 29
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“NCD-related DALYs are expected to rise by 27% across regions of Africa compared with 17% globally by 2020,[22,23] with more than half occurring prematurely (in persons <70 years of age).[22,24] In SA, adherence to the use of antiretroviral therapy (ART) has not only extended survival and ageing among HIVinfected indiv…”
BackgroundLiu, G., Niu, X., Meng, X., & Zhang, Z. (2018) · Journal of Thoracic Disease · doi:10.21037/jtd.2018.05.141 · Cited by 29
Liu, C., Shao, S., Liu, C., Bennett, G. G., Bettger, J. P., & Yan, L. L. (2019) · Digital Health · doi:10.1177/2055207619878627 · Cited by 29
Twagirumukiza, M., & Bortel, L. M. V. (2010) · Journal of Human Hypertension · doi:10.1038/jhh.2010.32 · Cited by 30
“In addition, hypertension bears the particularity of hitting the active young people, and then affecting the SSA economy”
BackgroundQuality of care and health status in Ukraine
Peabody, J. W., Luck, J., DeMaria, L., & Menon, R. (2014) · BMC Health Services Research · doi:10.1186/1472-6963-14-446 · Cited by 29
“The first is that the quality of care provided for NCDs (measured by physicians’ CPV® vignette scores) is a function of structural quality measures, physician characteristics, and control variables.”
BackgroundInfluentialNguyen, Q. N., Pham, S. T., Nguyen, V. L., Weinehall, L., Bonita, R., Byass, P., & Wall, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042825 · Cited by 29
“Introduction Three recent analyses of the trends in systolic blood pressure (BP), body mass index (BMI) and serum total cholesterol over the past generation raised concern about a global epidemic of risk factors for cardiovascular diseases (CVD) and called for actions to avoid catastrophic outcomes, especially in low…”
Background
Metadata
- Authors
- Abegunde, D. O., Mathers, C. D., Adam, T., Ortegon, M., & Strong, K.
- Affiliations
- World Health Organization (CH)
- Corresponding author
- Mathers, Colin D
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2007-12
- Volume
- 370
- Issue
- 9603
- Pages
- 1929-1938
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W1987313755
- Cited by
- 1,603
- References
- 45
- Citations by year
- 2026: 24 · 2025: 44 · 2024: 62 · 2023: 58 · 2022: 87 · 2021: 68 · 2020: 123 · 2019: 104 · 2018: 98 · 2017: 113 · 2016: 111 · 2015: 106 · 2014: 115 · 2013: 106 · 2012: 96
- FWCI
- 10.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Health and Epidemiology
- Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Global Health Care Issues
- Keywords
- chronic disease, disease burden, economic cost of illness, cardiovascular disease, cancer, chronic respiratory disease, diabetes mellitus, low-income countries, middle-income countries, sex differences in mortality, mortality averted, chronic disease prevention, global health goals
- MeSH terms
- Chronic Disease, Developing Countries, Female, Humans, Life Expectancy, Male, Registries, Global Health, Cost of Illness, Age Distribution, Sex Distribution
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