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The burden and costs of chronic diseases in low-income and middle-income countries.
Abstract
This paper estimates the disease burden and loss of economic output associated with chronic diseases-mainly cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes-in 23 selected countries which account for around 80% of the total burden of chronic disease mortality in developing countries. In these 23 selected low-income and middle-income countries, chronic diseases were responsible for 50% of the total disease burden in 2005. For 15 of the selected countries where death registration data are available, the estimated age-standardised death rates for chronic diseases in 2005 were 54% higher for men and 86% higher for women than those for men and women in high-income countries. If nothing is done to reduce the risk of chronic diseases, an estimated US$84 billion of economic production will be lost from heart disease, stroke, and diabetes alone in these 23 countries between 2006 and 2015. Achievement of a global goal for chronic disease prevention and control-an additional 2% yearly reduction in chronic disease death rates over the next 10 years-would avert 24 million deaths in these countries, and would save an estimated $8 billion, which is almost 10% of the projected loss in national income over the next 10 years.
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“Epidemiological transitions are defined by a shift from a heavy burden of infectious diseases to a major prevalence of noncommunicable diseases (NCDs)”
From Colonial transition as a major mediator of global health transition: lessons from the 2024 New Caledonia crisis (2025) · cites this paper as [3]
In the citing paper
“which currently account for about 80% of all deaths worldwide”
From Colonial transition as a major mediator of global health transition: lessons from the 2024 New Caledonia crisis (2025) · cites this paper as [3]
In the citing paper
“and are thus closely connected to the ageing of the populations – i.e. the demographic transition [3]”
From Colonial transition as a major mediator of global health transition: lessons from the 2024 New Caledonia crisis (2025) · cites this paper as [3]
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Rahardja, F. A., Chen, S., & Rahardja, U. (2022) · Sustainability · doi:10.3390/su14031537 · Cited by 59
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Population Ageing and Social Security in A sia
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Research needs for an improved primary care response to chronic non‐communicable diseases in Africa
Maher, D., Sekajugo, J., Harries, A. D., & Grosskurth, H. (2010) · Tropical Medicine & International Health · doi:10.1111/j.1365-3156.2009.02438.x · Cited by 57
“…the burden of ª 2009 Blackwell Publishing Ltd 177 long-term care on health systems and budgets, the costs that push households into further poverty, and the need for prevention in a situation in which risk factors often lie outside the direct control of the health sector (Abegunde et al. 2007).”
BackgroundQuantity and quality of carbohydrate intake in Iran: a target for nutritional intervention.
Bahreynian, M., & Esmaillzadeh, A. (2012) · PubMed · Cited by 57
Global Aspects of Cardiothoracic Surgery with Focus on Developing Countries
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“developing countries are challenged by the double burden of chronic noncommunicable diseases and the risk factors of hypertension, obesity, smoking, and urbanization, along with the lingering communicable diseases, especially tuberculosis, HIV/AIDS, and malaria.(20,21) Gaziano(8) described the epidemiological transiti…”
BackgroundAfrica and Nephrology: The Forgotten Continent
Katz, I. J., Gerntholtz, T. E., & Naicker, S. (2010) · Nephron Clinical Practice · doi:10.1159/000321524 · Cited by 56
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“This looming epidemic of hypertension and other related comorbidities (diabetes, heart diseases, and stroke) will account for the greatest burden of death, disability, and health expenditures in the near future [1,3,5].”
BackgroundDong, M., Wu, J., Ma, Z., Peretz‐Soroka, H., Zhang, M. Z., Komenda, P. V. J., Tangri, N., Liu, Y., Rigatto, C., & Lin, F. (2017) · Sensors · doi:10.3390/s17040684 · Cited by 56
Heart Failure In The Middle East Arab Countries: Current And Future Perspectives
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Non-communicable diseases in South Africa: A challenge to economic development
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Weinberger, K. (2013) · Food Security · doi:10.1007/s12571-013-0299-z · Cited by 55
“The “double burden of disease”, where undernutrition and obesity exist side-by-side, is observed both within communities and even within households (Abegunde et al. 2008; Yach et al. 2004).”
BackgroundThe increased range of cervical flexed motion detected by radiographs in Hirayama disease
Xu, X., Han, H., Gao, H., Hou, C., Fan, D., Fu, Y., & Sun, Y. (2010) · European Journal of Radiology · doi:10.1016/j.ejrad.2010.08.012 · Cited by 55
Grustam, A. S., Severens, J. L., van Nijnatten, J., Koymans, R., & Vrijhoef, H. J. (2014) · International Journal of Technology Assessment in Health Care · doi:10.1017/s0266462313000779 · Cited by 65
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“Moreover, these HBP-related diseases have an important social and economic impact as they also concern young active people and their financial cost is quite unaffordable for health systems particularly in developing countries [4, 5].”
BackgroundThe Global Spine Care Initiative: care pathway for people with spine-related concerns
Haldeman, S., Johnson, C. D., Chou, R., Nordin, M. C., Côté, P., Hurwitz, E. L., Green, B. N., Cedraschi, C., Acaroglu, E. R., Kopansky-Giles, D. R., et al. (2018) · European Spine Journal · doi:10.1007/s00586-018-5721-y · Cited by 55
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“Introduction Cardiovascular disease (CVD) is leading the growing burden of chronic noncommunicable diseases (NCD), including in developing countries [1-3].”
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“Abegunde et al point out that “two major factors account for the grim forecasts on the economic effect of chronic diseases: the lost labour units because of deaths from chronic disease and the costs of treating chronic disease, which continue to increase annually...” [5].”
InfluentialEnacted and implied stigma for dementia in a community in south‐west Nigeria
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“In China the largest share of the disease burden is due to NCDs [10].”
BackgroundPotential Co-exposure to Arsenic and Fluoride and Biomonitoring Equivalents for Mexican Children
Limón-Pacheco, J. H., Jiménez-Córdova, M. I., Cárdenas‐González, M., Retana, I. M. S., Gonsebatt, M. E., & Razo, L. M. D. (2018) · Annals of Global Health · doi:10.29024/aogh.913 · Cited by 54
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“7 million deaths globally each year, 80% of which occur in lowand middle-income countries.(4,5) Diet has been one the most studied factors in relation to the pathogenesis and progression of CVD.”
BackgroundCombating chronic disease in developing countries
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Metadata
- Authors
- Abegunde, D. O., Mathers, C. D., Adam, T., Ortegon, M., & Strong, K.
- Affiliations
- World Health Organization (CH)
- Corresponding author
- Mathers, Colin D
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2007-12
- Volume
- 370
- Issue
- 9603
- Pages
- 1929-1938
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W1987313755
- Cited by
- 1,603
- References
- 45
- Citations by year
- 2026: 24 · 2025: 44 · 2024: 62 · 2023: 58 · 2022: 87 · 2021: 68 · 2020: 123 · 2019: 104 · 2018: 98 · 2017: 113 · 2016: 111 · 2015: 106 · 2014: 115 · 2013: 106 · 2012: 96
- FWCI
- 10.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Health and Epidemiology
- Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Global Health Care Issues
- Keywords
- chronic disease, disease burden, economic cost of illness, cardiovascular disease, cancer, chronic respiratory disease, diabetes mellitus, low-income countries, middle-income countries, sex differences in mortality, mortality averted, chronic disease prevention, global health goals
- MeSH terms
- Chronic Disease, Developing Countries, Female, Humans, Life Expectancy, Male, Registries, Global Health, Cost of Illness, Age Distribution, Sex Distribution
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