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The burden and costs of chronic diseases in low-income and middle-income countries.

Abegunde, Dele O, Mathers, Colin D, Adam, Taghreed, Ortegon, Monica, Strong, Kathleen·2007·The Lancet

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Abstract

This paper estimates the disease burden and loss of economic output associated with chronic diseases-mainly cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes-in 23 selected countries which account for around 80% of the total burden of chronic disease mortality in developing countries. In these 23 selected low-income and middle-income countries, chronic diseases were responsible for 50% of the total disease burden in 2005. For 15 of the selected countries where death registration data are available, the estimated age-standardised death rates for chronic diseases in 2005 were 54% higher for men and 86% higher for women than those for men and women in high-income countries. If nothing is done to reduce the risk of chronic diseases, an estimated US$84 billion of economic production will be lost from heart disease, stroke, and diabetes alone in these 23 countries between 2006 and 2015. Achievement of a global goal for chronic disease prevention and control-an additional 2% yearly reduction in chronic disease death rates over the next 10 years-would avert 24 million deaths in these countries, and would save an estimated $8 billion, which is almost 10% of the projected loss in national income over the next 10 years.

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“6,28 The costs per death did not differ greatly from those found in our study (US$ 22,904), while the ratio of this cost per death between sexes was lower (1.28) than the 1.45 estimated for CVD.”
ResultInfluential
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“11,12 A connection is noted between the prevalence of NCDs, and reduced physical activity 12 , inadequate consumption of vegetables, coupled with excessive use of diets in saturated fats, salt, and calories 13 and an association 14 between hypertension and excessive salt consumption is also seen.”
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“Although typically considered a ‘disease of the rich’, most of those affected now live in low‐ and middle‐income countries (LMICs) [2], where social safety nets are weak, and the consequences of uncontrolled hypertension can be catastrophic [3, 4].”
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“It is, however, estimated that an additional 2% annual reduction in death from these conditions would gain about 500 million years of life and save around $8 million dollars in low- to middle-income countries by reducing lost productivity.(3,4) It is therefore important to fully consider effective long-term prophylact…”
Background
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“gov chronic disease in countries with low or intermediate levels of income.(2) Unfortunately, reporting on causes of death across the world has been hindered by limited, incomplete, and uncertain data, but some estimates are available.”
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“8 million stroke deaths by 2030 in the absence of significant global public health response [1].”
Background
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McKenzie, B. L., Waqa, G., Mounsey, S., Johnson, C., Woodward, M., Buse, K., Thow, A. M., McLean, R. M., & Webster, J. L. (2022) · International Journal for Equity in Health · doi:10.1186/s12939-022-01745-x · Cited by 5
“countries (LMICs) compared to women in high-income countries [2].”
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Physiotherapy management of patients with coronary artery disease: a report on current practice in South Africa
Roos, R., & van Aswegen, H. (2011) · South African Journal of Physiotherapy · doi:10.4102/sajp.v67i1.33 · Cited by 5
“Epidemiological transition results in the shift of major causes of death from infectious diseases and nutritional defi of death in developing countries by 2030 (Abegunde et al 2007).”
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Enhanced Diabetes Susceptibility in Community Dwelling Han Elders Carrying the Apolipoprotein E 3/3 Genotype
Ban, C., Zhong, L., Wang, T., Zhu, M., Wang, J., Zhen-lian, Z., Wang, Z., Su, N., Liu, Y.-Y., Yan-chen, S., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151336 · Cited by 5
“7 million by 2030 [4], with the burden of disease being especially heavy in developing countries [5].”
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Planning a Radiotherapy Department
van der Merwe, D. (2016) · Clinical Oncology · doi:10.1016/j.clon.2016.10.006 · Cited by 5
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KMRC011, an agonist of toll-like receptor 5, mitigates irradiation-induced tissue damage and mortality in cynomolgus monkeys
Lee, H.-S., Cho, D., Han, J., Han, S.-C., Woo, S. K., Jun, S.-Y., Lee, W., Yoon, S., Pak, S.-I., Lee, S.-J., et al. (2020) · Journal of Immunotoxicology · doi:10.1080/1547691x.2019.1699617 · Cited by 5
Essential medicines pricing—reform needed
Vasan, A., & Kim, J. Y. (2008) · The Lancet · doi:10.1016/s0140-6736(08)61763-8 · Cited by 5
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Azinge, N. O. (2013) · Orient Journal of Medicine · Cited by 5
Prognostic factors of 28 days survival rate in patients with a first acute myocardial infarction based on gender in Isfahan, Iran (2000-2009).
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“De igual forma complementa estudios con respecto a la carga del cuidado para el sistema [43-45], para la familia [46] y para el cuidador familiar [47], involucrando al sujeto directamente implicado en la experiencia de vivir con una enfermedad crónica.”
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Untitled work
(2012) · RePEc: Research Papers in Economics · Cited by 1,951

Authors: Abegunde, D. O., Mathers, C. D., Adam, T., Ortegon, M., & Strong, K.
Affiliations: World Health Organization (CH)
Corresponding author: Mathers, Colin D
ORCID: Mathers, Colin D
Adam, Taghreed
Strong, Kathleen
Venue: The Lancet
Publisher: Elsevier BV
Published: 2007-12
Volume: 370
Issue: 9603
Pages: 1929-1938
ISSN: 0099-5355 (ISSN-L)
0140-6736
DOI: 10.1016/s0140-6736(07)61696-1
OpenAlex: W1987313755
Cited by: 1,603
References: 45
Citations by year: 2026: 24 · 2025: 44 · 2024: 62 · 2023: 58 · 2022: 87 · 2021: 68 · 2020: 123 · 2019: 104 · 2018: 98 · 2017: 113 · 2016: 111 · 2015: 106 · 2014: 115 · 2013: 106 · 2012: 96
FWCI: 10.28
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Health and Epidemiology
Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Global Health Care Issues
Keywords: chronic disease, disease burden, economic cost of illness, cardiovascular disease, cancer, chronic respiratory disease, diabetes mellitus, low-income countries, middle-income countries, sex differences in mortality, mortality averted, chronic disease prevention, global health goals
MeSH terms: Chronic Disease, Developing Countries, Female, Humans, Life Expectancy, Male, Registries, Global Health, Cost of Illness, Age Distribution, Sex Distribution

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The burden and costs of chronic diseases in low-income and middle-income countries.

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