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The burden and costs of chronic diseases in low-income and middle-income countries.
Abstract
This paper estimates the disease burden and loss of economic output associated with chronic diseases-mainly cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes-in 23 selected countries which account for around 80% of the total burden of chronic disease mortality in developing countries. In these 23 selected low-income and middle-income countries, chronic diseases were responsible for 50% of the total disease burden in 2005. For 15 of the selected countries where death registration data are available, the estimated age-standardised death rates for chronic diseases in 2005 were 54% higher for men and 86% higher for women than those for men and women in high-income countries. If nothing is done to reduce the risk of chronic diseases, an estimated US$84 billion of economic production will be lost from heart disease, stroke, and diabetes alone in these 23 countries between 2006 and 2015. Achievement of a global goal for chronic disease prevention and control-an additional 2% yearly reduction in chronic disease death rates over the next 10 years-would avert 24 million deaths in these countries, and would save an estimated $8 billion, which is almost 10% of the projected loss in national income over the next 10 years.
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“Epidemiological transitions are defined by a shift from a heavy burden of infectious diseases to a major prevalence of noncommunicable diseases (NCDs)”
From Colonial transition as a major mediator of global health transition: lessons from the 2024 New Caledonia crisis (2025) · cites this paper as [3]
In the citing paper
“which currently account for about 80% of all deaths worldwide”
From Colonial transition as a major mediator of global health transition: lessons from the 2024 New Caledonia crisis (2025) · cites this paper as [3]
In the citing paper
“and are thus closely connected to the ageing of the populations – i.e. the demographic transition [3]”
From Colonial transition as a major mediator of global health transition: lessons from the 2024 New Caledonia crisis (2025) · cites this paper as [3]
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Malekshahi, H., Bahrami, G., Miraghaee, S., Ahmadi, S. A., Sajadimajd, S., Hatami, R., Mohammadi, B., & Keshavarzi, S. (2019) · Journal of Food Biochemistry · doi:10.1111/jfbc.13021 · Cited by 23
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Metadata
- Authors
- Abegunde, D. O., Mathers, C. D., Adam, T., Ortegon, M., & Strong, K.
- Affiliations
- World Health Organization (CH)
- Corresponding author
- Mathers, Colin D
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2007-12
- Volume
- 370
- Issue
- 9603
- Pages
- 1929-1938
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W1987313755
- Cited by
- 1,603
- References
- 45
- Citations by year
- 2026: 24 · 2025: 44 · 2024: 62 · 2023: 58 · 2022: 87 · 2021: 68 · 2020: 123 · 2019: 104 · 2018: 98 · 2017: 113 · 2016: 111 · 2015: 106 · 2014: 115 · 2013: 106 · 2012: 96
- FWCI
- 10.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Health and Epidemiology
- Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Global Health Care Issues
- Keywords
- chronic disease, disease burden, economic cost of illness, cardiovascular disease, cancer, chronic respiratory disease, diabetes mellitus, low-income countries, middle-income countries, sex differences in mortality, mortality averted, chronic disease prevention, global health goals
- MeSH terms
- Chronic Disease, Developing Countries, Female, Humans, Life Expectancy, Male, Registries, Global Health, Cost of Illness, Age Distribution, Sex Distribution
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