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Temporal Interaction between Single Spikes and Complex Spike Bursts in Hippocampal Pyramidal Cells
Open accessAbstract
Cortical pyramidal cells fire single spikes and complex spike bursts. However, neither the conditions necessary for triggering complex spikes, nor their computational function are well understood. CA1 pyramidal cell burst activity was examined in behaving rats. The fraction of bursts was not reliably higher in place field centers, but rather in places where discharge frequency was 6-7 Hz. Burst probability was lower and bursts were shorter after recent spiking activity than after prolonged periods of silence (100 ms-1 s). Burst initiation probability and burst length were correlated with extracellular spike amplitude and with intracellular action potential rising slope. We suggest that bursts may function as "conditional synchrony detectors," signaling strong afferent synchrony after neuronal silence, and that single spikes triggered by a weak input may suppress bursts evoked by a subsequent strong input.
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“Units were deemed independent from each other by i) their distinct spike waveform, ii) the absence of refractory period in their cross-correlations and iii) separable principal component boundaries using a measure based on the Mahalanobis distance24,26.”
From Dopaminergic neurons promote hippocampal reactivation and spatial memory persistence (2014) · cites this paper as [26]
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Cites
The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat
O'Keefe, J., & Dostrovsky, J. (1971) · Brain Research · doi:10.1016/0006-8993(71)90358-1 · Cited by 6,151
Bi, G.-Q., & Poo, M.-M. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-24-10464.1998 · Cited by 4,744
Regulation of Synaptic Efficacy by Coincidence of Postsynaptic APs and EPSPs
Markram, H., Lübke, J., Frotscher, M., & Sakmann, B. (1997) · Science · doi:10.1126/science.275.5297.213 · Cited by 3,832
Interneurons of the hippocampus
Freund, T. F., & Buzsáki, G. (1998) · Hippocampus · doi:10.1002/(sici)1098-1063(1996)6:4 · Cited by 3,478
Self-citationBursts as a unit of neural information: making unreliable synapses reliable
Lisman, J. E. (1997) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)10070-9 · Cited by 1,418
A Synaptically Controlled, Associative Signal for Hebbian Plasticity in Hippocampal Neurons
Magee, J. C., & Johnston, D. (1997) · Science · doi:10.1126/science.275.5297.209 · Cited by 1,340
Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats
Ranck, J. B. (1973) · Experimental Neurology · doi:10.1016/0014-4886(73)90290-2 · Cited by 1,322
Electric current flow in excitable cells
(1976) · American Heart Journal · doi:10.1016/s0002-8703(76)80560-1 · Cited by 1,289
Harris, K. D., Henze, D. A., Csicsvari, J. L., Hirase, H., & Buzsáki, G. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.84.1.401 · Cited by 1,153
Self-citationElectrophysiological properties of neocortical neurons in vitro.
Connors, B. W., Gutnick, M., & Prince, D. (1982) · Journal of Neurophysiology · doi:10.1152/jn.1982.48.6.1302 · Cited by 954
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Buzsáki, G. (2015) · Hippocampus · doi:10.1002/hipo.22488 · Cited by 1,759
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Buzsáki, G. (2004) · Nature Neuroscience · doi:10.1038/nn1233 · Cited by 1,875
Self-citationBrain-state- and cell-type-specific firing of hippocampal interneurons in vivo
Klausberger, T., Magill, P. J., Márton, L. F., Roberts, J. D. B., Cobden, P. M., Buzsáki, G., & Somogyi, P. (2003) · Nature · doi:10.1038/nature01374 · Cited by 1,345
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Dupret, D., O'Neill, J., Pleydell-Bouverie, B., & Csicsvari, J. (2010) · Nature Neuroscience · doi:10.1038/nn.2599 · Cited by 769
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Royer, S., Zemelman, B. V., Losonczy, A., Kim, J., Chance, F., Magee, J. C., & Buzsáki, G. (2012) · Nature Neuroscience · doi:10.1038/nn.3077 · Cited by 728
Self-citationMizuseki, K., Sirota, A., Pastalkova, E., & Buzsáki, G. (2009) · Neuron · doi:10.1016/j.neuron.2009.08.037 · Cited by 718
Self-citationDistinct behavioural and network correlates of two interneuron types in prefrontal cortex
Kvitsiani, D., Ranade, S., Hangya, B., Taniguchi, H., Huang, J. Z., & Kepecs, A. (2013) · Nature · doi:10.1038/nature12176 · Cited by 516
Dendritic Inhibition in the Hippocampus Supports Fear Learning
Lovett-Barron, M., Kaifosh, P., Kheirbek, M. A., Danielson, N., Zaremba, J. D., Reardon, T. R., Turi, G. F., Hen, R., Zemelman, B. V., & Losonczy, A. (2014) · Science · doi:10.1126/science.1247485 · Cited by 509
Dopaminergic neurons promote hippocampal reactivation and spatial memory persistence
McNamara, C. G., Tejero-Cantero, Á., Trouche, S., Campo-Urriza, N., & Dupret, D. (2014) · Nature Neuroscience · doi:10.1038/nn.3843 · Cited by 486
Klausberger, T., Marton, L. F., O'Neill, J., Huck, J. H. J., Dalezios, Y., Fuentealba, P., Suen, W. Y., Papp, E., Kaneko, T., Watanabe, M., et al. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3269-05.2005 · Cited by 469
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Csicsvari, J., Henze, D. A., Jamieson, B., Harris, K. D., Sirota, A., Barthó, P., Wise, K. D., & Buzsáki, G. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00116.2003 · Cited by 402
Self-citationSpike train dynamics predicts theta-related phase precession in hippocampal pyramidal cells
Harris, K. D., Henze, D. A., Hirase, H., Leinekugel, X., Dragoi, G., Czurkó, A., & Buzsáki, G. (2002) · Nature · doi:10.1038/nature00808 · Cited by 398
Self-citationTheta and gamma coordination of hippocampal networks during waking and rapid eye movement sleep.
Montgomery, S. M., Sirota, A., & Buzsaki, G. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1227-08.2008 · Cited by 371
Klausberger, T., Márton, L. F., Baude, A., Roberts, J. D. B., Magill, P. J., & Somogyi, P. (2004) · Nature Neuroscience · doi:10.1038/nn1159 · Cited by 393
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Robbe, D., Montgomery, S. M., Thome, A., Rueda-Orozco, P. E., McNaughton, B. L., & Buzsaki, G. (2006) · Nature Neuroscience · doi:10.1038/nn1801 · Cited by 333
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O'Neill, J., Senior, T. J., Allen, K., Huxter, J. R., & Csicsvari, J. (2008) · Nature Neuroscience · doi:10.1038/nn2037 · Cited by 318
The entorhinal cognitive map is attracted to goals
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O'Neill, J., Senior, T., & Csicsvari, J. (2006) · Neuron · doi:10.1016/j.neuron.2005.10.037 · Cited by 281
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Perge, J. A., Homer, M. L., Malik, W. Q., Cash, S., Eskandar, E., Friehs, G., Donoghue, J. P., & Hochberg, L. R. (2013) · Journal of Neural Engineering · doi:10.1088/1741-2560/10/3/036004 · Cited by 243
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Gridchyn, I., Schoenenberger, P., O’Neill, J., & Csicsvari, J. (2020) · Neuron · doi:10.1016/j.neuron.2020.01.021 · Cited by 178
Le Van Quyen, M., Staba, R., Bragin, A., Dickson, C., Valderrama, M., Fried, I., & Engel, J. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.5049-09.2010 · Cited by 189
Katona, L., Lapray, D., Viney, T. J., Oulhaj, A., Borhegyi, Z., Micklem, B. R., Klausberger, T., & Somogyi, P. (2014) · Neuron · doi:10.1016/j.neuron.2014.04.007 · Cited by 169
Social and novel contexts modify hippocampal CA2 representations of space
Alexander, G. M., Farris, S., Pirone, J. R., Zheng, C., Colgin, L. L., & Dudek, S. M. (2016) · Nature Communications · doi:10.1038/ncomms10300 · Cited by 191
Superficial layers of the medial entorhinal cortex replay independently of the hippocampus
O’Neill, J., Boccara, C. N., Stella, F., Schoenenberger, P., & Csicsvari, J. (2017) · Science · doi:10.1126/science.aag2787 · Cited by 177
Back to front: cerebellar connections and interactions with the prefrontal cortex
Watson, T. C., Becker, N., Apps, R., & Jones, M. W. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00004 · Cited by 176
Lee, S.-H., Foldy, C., & Soltesz, I. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.6238-09.2010 · Cited by 114
Burst Firing Synchronizes Prefrontal and Anterior Cingulate Cortex during Attentional Control
Womelsdorf, T., Ardid, S., Everling, S., & Valiante, T. A. (2014) · Current Biology · doi:10.1016/j.cub.2014.09.046 · Cited by 113
Trettel, S. G., Trimper, J. B., Hwaun, E., Fiete, I. R., & Colgin, L. L. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0359-6 · Cited by 108
Hippocampal replay of experience at real-world speeds
Denovellis, E. L., Gillespie, A. K., Coulter, M. E., Sosa, M., Chung, J. E., Eden, U. T., & Frank, L. M. (2021) · eLife · doi:10.7554/elife.64505 · Cited by 89
Tanni, S., de Cothi, W., & Barry, C. (2022) · Current Biology · doi:10.1016/j.cub.2022.06.046 · Cited by 37
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Metadata
- Authors
- Harris, K. D., Hirase, H., Leinekugel, X., Henze, D. A., & Buzsáki, G.
- Affiliations
- Rutgers, The State University of New Jersey (US)
- Corresponding author
- Buzsáki, György
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2001-10
- Volume
- 32
- Issue
- 1
- Pages
- 141-149
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2112782685
- Cited by
- 388
- References
- 47
- Citations by year
- 2026: 13 · 2025: 15 · 2024: 16 · 2023: 12 · 2022: 24 · 2021: 19 · 2020: 9 · 2019: 13 · 2018: 9 · 2017: 16 · 2016: 23 · 2015: 25 · 2014: 26 · 2013: 16 · 2012: 23
- FWCI
- 5.50
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- National Institutes of Health (MH12403, MH54671, NS34994)
- Uehara Memorial Foundation
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- single spike, CA1 pyramidal neurons, spike timing, burst duration, spike amplitude, spike-timing-dependent plasticity
- MeSH terms
- Action Potentials, Animals, Behavior, Animal, Electrophysiology, Hippocampus, Male, Time Factors, Pyramidal Cells, Rats, Long-Evans, Rats
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