Theta and gamma coordination of hippocampal networks during waking and rapid eye movement sleep.
Open accessAbstract
Rapid eye movement (REM) sleep has been considered a paradoxical state because, despite the high behavioral threshold to arousing perturbations, gross physiological patterns in the forebrain resemble those of waking states. To understand how intrahippocampal networks interact during REM sleep, we used 96 site silicon probes to record from different hippocampal subregions and compared the patterns of activity during waking exploration and REM sleep. Dentate/CA3 theta and gamma synchrony was significantly higher during REM sleep compared with active waking. In contrast, gamma power in CA1 and CA3-CA1 gamma coherence showed significant decreases in REM sleep. Changes in unit firing rhythmicity and unit-field coherence specified the local generation of these patterns. Although these patterns of hippocampal network coordination characterized the more common tonic periods of REM sleep (approximately 95% of total REM), we also detected large phasic bursts of local field potential power in the dentate molecular layer that were accompanied by transient increases in the firing of dentate and CA1 neurons. In contrast to tonic REM periods, phasic REM epochs were characterized by higher theta and gamma synchrony among the dentate, CA3, and CA1 regions. These data suggest enhanced dentate processing, but limited CA3-CA1 coordination during tonic REM sleep. In contrast, phasic bursts of activity during REM sleep may provide windows of opportunity to synchronize the hippocampal trisynaptic loop and increase output to cortical targets. We hypothesize that tonic REM sleep may support off-line mnemonic processing, whereas phasic bursts of activity during REM may promote memory consolidation.
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Within hippocampal circuitry, gamma band activity shows reduced coherence across CA3 and CA1 during tonic REM sleep compared with wake exploration.
“Similarly, within hippocampal circuitry, gamma band activity shows reduced coherence across the CA3 and CA1 regions during tonic REM sleep compared with activity during wake exploration (834)”
From About Sleep's Role in Memory (2013) · cites this paper as [834]
Such phasic electrographic events were observed preceding the vast majority of the VS events in all brain regions.
“Such phasic electrographic events have been described previously in rodents and cats, where they are thought to transiently synchronize hippocampal networks18,19 and were observed preceding the vast majority of the VS events in all brain regions.”
From Local hippocampal fast gamma rhythms precede brain-wide hyperemic patterns during spontaneous rodent REM sleep (2018) · cites this paper as [18]
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Neuronal Oscillations in Cortical Networks
Buzsáki, G., & Draguhn, A. (2004) · Science · doi:10.1126/science.1099745 · Cited by 6,576 · see citing works
Self-citationGray, C. M., König, P., Engel, A. K., & Singer, W. (1989) · Nature · doi:10.1038/338334a0 · Cited by 4,183 · see citing works
Dynamic predictions: Oscillations and synchrony in top–down processing
Engel, A. K., Fries, P., & Singer, W. (2001) · Nature Reviews Neuroscience · doi:10.1038/35094565 · Cited by 3,454 · see citing works
Theta oscillations in the hippocampus
Buzsáki, G. (2002) · Neuron · doi:10.1016/s0896-6273(02)00586-x · Cited by 3,332 · see citing works
Regularly Occurring Periods of Eye Motility, and Concomitant Phenomena, During Sleep
Aserinsky, E., & Kleitman, N. (1953) · Science · doi:10.1126/science.118.3062.273 · Cited by 2,488 · see citing works
Dynamics of the Hippocampal Ensemble Code for Space
Wilson, M. A., & McNaughton, B. L. (1993) · Science · doi:10.1126/science.8351520 · Cited by 2,350 · see citing works
Aston-Jones, G., & Bloom, F. (1981) · The Journal of Neuroscience · doi:10.1523/jneurosci.01-08-00876.1981 · Cited by 1,960 · see citing works
Hippocampal electrical activity and voluntary movement in the rat
Vanderwolf, C. H. (1969) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(69)90092-3 · Cited by 1,928 · see citing works
The functional states of the thalamus and the associated neuronal interplay.
Steriade, M., & Llinas, R. R. (1988) · Physiological Reviews · doi:10.1152/physrev.1988.68.3.649 · Cited by 1,746 · see citing works
Two-stage model of memory trace formation: A role for “noisy” brain states
Buzsáki, G. (1989) · Neuroscience · doi:10.1016/0306-4522(89)90423-5 · Cited by 1,709 · see citing works
Self-citationMitzdorf, U. (1985) · Physiological Reviews · doi:10.1152/physrev.1985.65.1.37 · Cited by 1,690 · see citing works
Pattern Separation in the Dentate Gyrus and CA3 of the Hippocampus
Leutgeb, J. K., Leutgeb, S., Moser, M.-B., & Moser, E. I. (2007) · Science · doi:10.1126/science.1135801 · Cited by 1,601 · cited 2× · see citing works
“More broadly, during REM sleep, the dentate may engage pattern separation (Rolls, 1996; Leutgeb et al., 2007) and/or recombination of previous memories to facilitate novel inferences (Walker and Stickgold, 2004).”
BackgroundGamma (40-100 Hz) oscillation in the hippocampus of the behaving rat
Bragin, A., Jando, G., Nadasdy, Z., Hetke, J., Wise, K., & Buzsaki, G. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-01-00047.1995 · Cited by 1,527 · see citing works
Self-citationStudies on single neurons in dorsal hippocampal formation and septum in unrestrained rats
Ranck, J. B. (1973) · Experimental Neurology · doi:10.1016/0014-4886(73)90290-2 · Cited by 1,322 · see citing works
High-frequency network oscillation in the hippocampus
Buzsáki, G., Horváth, Z., Urioste, R., Hetke, J. F., & Wise, K. D. (1992) · Science · doi:10.1126/science.1589772 · Cited by 1,223 · see citing works
Harris, K. D., Henze, D. A., Csicsvari, J. L., Hirase, H., & Buzsáki, G. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.84.1.401 · Cited by 1,153 · see citing works
Temporally structured replay of awake hippocampal ensemble activity during rapid eye movement sleep
Louie, K., & Wilson, M. A. (2001) · Neuron · doi:10.1016/s0896-6273(01)00186-6 · Cited by 1,148 · see citing works
Sleep-Dependent Learning and Memory Consolidation
Walker, M. P., & Stickgold, R. (2004) · Neuron · doi:10.1016/j.neuron.2004.08.031 · Cited by 1,113 · cited 5× · see citing works
“Numerous functions have been postulated for REM sleep since its discovery 50 years ago (Aserinsky and Kleitman, 1953), but the best consensus is that we need a better understanding of REM sleep physiology to shape our functional theories (Gottesmann, 2001; Walker and Stickgold, 2004).”
BackgroundInfluentialMechanisms of Gamma Oscillations in the Hippocampus of the Behaving Rat
Csicsvari, J., Jamieson, B. G., Wise, K. D., & Buzsáki, G. (2003) · Neuron · doi:10.1016/s0896-6273(02)01169-8 · Cited by 990 · see citing works
The physiology of brain histamine
Brown, R. E., Stevens, D. R., & Haas, H. L. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00039-3 · Cited by 983 · see citing works
Oscillatory coupling of hippocampal pyramidal cells and interneurons in the behaving rat
Csicsvari, J., Hirase, H., Czurkó, A., Mamiya, A., & Buzsáki, G. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-01-00274.1999 · Cited by 966 · see citing works
Dorsal raphe neurons: depression of firing during sleep in cats
McGinty, D., & Harper, R. M. (1976) · Brain Research · doi:10.1016/0006-8993(76)90480-7 · Cited by 900 · see citing works
Analysis of Dynamic Brain Imaging Data
Mitra, P. P., & Pesaran, B. (1998) · Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory) · Cited by 898 · see citing works
Barthó, P., Hirase, H., Monconduit, L., Zugaro, M. B., Harris, K. D., & Buzsáki, G. (2004) · Journal of Neurophysiology · doi:10.1152/jn.01170.2003 · Cited by 888 · see citing works
Cholinergic induction of network oscillations at 40 Hz in the hippocampus in vitro
Fisahn, A., Pike, F. G., Buhl, E. H., & Paulsen, O. (1998) · Nature · doi:10.1038/28179 · Cited by 884 · see citing works
Organization of cell assemblies in the hippocampus
Harris, K. D., Csicsvari, J., Hirase, H., Dragoi, G., & Buzsáki, G. (2003) · Nature · doi:10.1038/nature01834 · Cited by 869 · see citing works
Crick, F., & Mitchison, G. (1983) · Nature · doi:10.1038/304111a0 · Cited by 865 · see citing works
The cognitive neuroscience of sleep: neuronal systems, consciousness and learning
Hobson, J. A., & Pace-Schott, E. F. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn915 · Cited by 835 · see citing works
Corticothalamic resonance, states of vigilance and mentation
Steriade, M. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00353-5 · Cited by 817 · see citing works
Kramis, R., Vanderwolf, C. H., & Bland, B. H. (1975) · Experimental Neurology · doi:10.1016/0014-4886(75)90195-8 · Cited by 791 · see citing works
(1997) · Neuroscience · doi:10.1016/s0306-4522(97)00239-x · Cited by 707 · see citing works
Very Slow Activity Fluctuations in Monkey Visual Cortex: Implications for Functional Brain Imaging
Leopold, D. A. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.4.422 · Cited by 675 · see citing works
Llinás, R. R., & Paré, D. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90075-y · Cited by 641 · see citing works
The REM sleep-memory consolidation hypothesis
Siegel, J. M. (2001) · Science · doi:10.1126/science.1063049 · Cited by 568 · see citing works
Whishaw, I. Q., & Vanderwolf, C. H. (1973) · Behavioral Biology · doi:10.1016/s0091-6773(73)80041-0 · Cited by 508 · see citing works
Isomura, Y., Sirota, A., Özen, S., Montgomery, S., Mizuseki, K., Henze, D. A., & Buzsáki, G. (2006) · Neuron · doi:10.1016/j.neuron.2006.10.023 · Cited by 500 · see citing works
Self-citationHazan, L., Zugaro, M. B., & Buzsáki, G. (2006) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2006.01.017 · Cited by 492 · see citing works
Marrosu, F., Portas, C., Mascia, M. S., Casu, M. A., Fà, M., Giagheddu, M., Imperato, A., & Gessa, G. L. (1995) · Brain Research · doi:10.1016/0006-8993(94)01399-3 · Cited by 480 · see citing works
Gamma oscillations dynamically couple hippocampal CA3 and CA1 regions during memory task performance
Montgomery, S. M., & Buzsáki, G. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701826104 · Cited by 431 · see citing works
Self-citationHu, H., Vervaeke, K., & Storm, J. F. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.029249 · Cited by 410 · see citing works
Massively Parallel Recording of Unit and Local Field Potentials With Silicon-Based Electrodes
Csicsvari, J., Henze, D. A., Jamieson, B., Harris, K. D., Sirota, A., Barthó, P., Wise, K. D., & Buzsáki, G. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00116.2003 · Cited by 402 · see citing works
Self-citationSampling Properties of the Spectrum and Coherency of Sequences of Action Potentials
Jarvis, M. R., & Mitra, P. P. (2001) · Neural Computation · doi:10.1162/089976601300014312 · Cited by 392 · see citing works
Temporal Interaction between Single Spikes and Complex Spike Bursts in Hippocampal Pyramidal Cells
Harris, K. D., Hirase, H., Leinekugel, X., Henze, D. A., & Buzsáki, G. (2001) · Neuron · doi:10.1016/s0896-6273(01)00447-0 · Cited by 388 · see citing works
The relation of eye movements, body motility, and external stimuli to dream content
Dement, W., & Wolpert, E. A. (1958) · Journal of Experimental Psychology · doi:10.1037/h0040031 · Cited by 372 · see citing works
Organization of histaminergic fibers in the rat brain
Inagaki, N., Yamatodani, A., Ando‐Yamamoto, M., Tohyama, M., Watanabe, T., & Wada, H. (1988) · The Journal of Comparative Neurology · doi:10.1002/cne.902730302 · Cited by 367 · see citing works
Experience-dependent phase-reversal of hippocampal neuron firing during REM sleep
Poe, G. R., Nitz, D. A., McNaughton, B. L., & Barnes, C. A. (2000) · Brain Research · doi:10.1016/s0006-8993(99)02310-0 · Cited by 318 · see citing works
Sleep-Dependent θ Oscillations in the Human Hippocampus and Neocortex
Cantero, J. L., Atienza, M., Stickgold, R., Kahana, M. J., Madsen, J. R., & Kocsis, B. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-34-10897.2003 · Cited by 312 · see citing works
McClelland, J. L., & Goddard, N. (1996) · Hippocampus · doi:10.1002/(sici)1098-1063(1996)6:6 · Cited by 262 · see citing works
Brain Gene Expression During REM Sleep Depends on Prior Waking ExperiencePreprint
Ribeiro, S. T. G., Goyal, V., Mello, C. V., & Pavlides, C. (1999) · Learning & Memory · doi:10.1101/lm.6.5.500 · Cited by 260 · see citing works
Endogenous sleep-promoting substances and sleep regulation
Borbely, A. A., & Tobler, I. (1989) · Physiological Reviews · doi:10.1152/physrev.1989.69.2.605 · Cited by 259 · cited 1× · see citing works
“Sleep is not a homogeneous state, but is composed of various stages of slow-wave sleep and rapid eye movement (REM) sleep (Steriade and Llinas, 1988; Borbely and Tobler, 1989).”
BackgroundBuzsáki, G., Czopf, J., Kondákor, I., & Kellényi, L. (1986) · Brain Research · doi:10.1016/0006-8993(86)90729-8 · Cited by 250 · see citing works
Insausti, R., & Amaral, D. G. (2004) · Elsevier eBooks · doi:10.1016/b978-012547626-3/50024-7 · Cited by 246 · see citing works
Bragin, A., Jandó, G., Nádasdy, Z., van Landeghem, M., & Buzsáki, G. (1995) · Journal of Neurophysiology · doi:10.1152/jn.1995.73.4.1691 · Cited by 237 · see citing works
Wehrle, R., Kaufmann, C., Wetter, T. C., Holsboer, F., Auer, D. P., Pollmächer, T., & Czisch, M. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05314.x · Cited by 224 · see citing works
Self-Motion and the Hippocampal Spatial Metric
Terrazas, A., Krause, M., Lipa, P., Gothard, K. M., Barnes, C. A., & McNaughton, B. L. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0693-05.2005 · Cited by 220 · see citing works
The Atonia and Myoclonia of Active (REM) Sleep
Chase, M. H., & Morales, F. R. (1990) · Annual Review of Psychology · doi:10.1146/annurev.ps.41.020190.003013 · Cited by 208 · see citing works
Vertes, R. P. (2004) · Neuron · doi:10.1016/j.neuron.2004.08.034 · Cited by 188 · see citing works
Chu, N., & Bloom, F. E. (1973) · Science · doi:10.1126/science.179.4076.908 · Cited by 165 · see citing works
Datta, S., Mavanji, V., Ulloor, J., & Patterson, E. H. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4111-03.2004 · Cited by 162 · see citing works
Cellular Basis of Pontine Ponto-geniculo-occipital Wave Generation and Modulation
Datta, S. (1997) · Cellular and Molecular Neurobiology · doi:10.1023/a:1026398402985 · Cited by 156 · see citing works
Evoked potentials as a tool for the investigation of human sleep
Bastuji, H. (1999) · Sleep Medicine Reviews · doi:10.1016/s1087-0792(99)90012-6 · Cited by 150 · see citing works
Two types of cerebral activation during active sleep: relations to behavior
Robinson, T. E., Kramis, R. C., & Vanderwolf, C. H. (1977) · Brain Research · doi:10.1016/0006-8993(77)90954-4 · Cited by 148 · see citing works
Reflexes involving triceps surae from the ankle joint of the cat
Chambers, W. W., Liu, C. N., McCouch, G. P., & Yu, J. (1973) · Experimental Neurology · doi:10.1016/0014-4886(73)90030-7 · Cited by 138 · see citing works
On the mechanism of histaminergic inhibition of glutamate release in the rat dentate gyrus
Brown, R. E., & Haas, H. L. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.777ab.x · Cited by 132 · see citing works
Rhythmic hippocampal slow oscillation characterizes REM sleep in humans
Bódizs, R., Kántor, S., Szabó, G., Szûcs, A., Erõss, L., & Halász, P. (2001) · Hippocampus · doi:10.1002/hipo.1090 · Cited by 113 · see citing works
Brain structures and mechanisms involved in the generation of REM sleep
Reinoso‐Suárez, F., de Andrés, I., Rodrigo‐Angulo, M. L., & Garzón, M. (2001) · Sleep Medicine Reviews · doi:10.1053/smrv.2000.0136 · Cited by 108 · see citing works
Eye Movements during Active and Passive Dreams
Berger, R. J., & Oswald, I. (1962) · Science · doi:10.1126/science.137.3530.601 · Cited by 106 · see citing works
The action of norepinephrine in the rat hippocampus: Intracellular studies in the slice preparation
Segal, M. (1981) · Brain Research · doi:10.1016/0006-8993(81)90104-9 · Cited by 104 · see citing works
The paradox of sleep: the story of dreaming
(2000) · Choice Reviews Online · doi:10.5860/choice.37-2763 · Cited by 100 · see citing works
Operational Dynamics in the Hippocampal-entorhinal Axis
Chrobak, J. J. (1998) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(97)00016-x · Cited by 92 · see citing works
Histaminergic modulation of synaptic plasticity in area CA1 of rat hippocampal slices
Brown, R. E., Fedorov, N. B., Haas, H. I., & Reymann, K. (1995) · Neuropharmacology · doi:10.1016/0028-3908(94)00138-i · Cited by 90 · see citing works
Wyble, B., Hyman, J. M., Rossi, C. A., & Hasselmo, M. E. (2004) · Hippocampus · doi:10.1002/hipo.20012 · Cited by 87 · see citing works
Mechanisms underlying gamma (‘40 Hz’) network oscillations in the hippocampus—a mini-review
Mann, E. O., & Paulsen, O. (2004) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2004.06.004 · Cited by 74 · see citing works
Theta rhythm during REM sleep and waking: Correlations between power, phase and frequency
Leung, L.-W. S. (1984) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(84)90045-2 · Cited by 72 · see citing works
Park, S. P., Lopez-Rodriguez, F., Wilson, C. L., Maidment, N. T., Matsumoto, Y., & Engel, J. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01511-5 · Cited by 66 · see citing works
Eye movements and hippocampal theta activity in cats
Sakai, K., Sano, K., & Iwahara, S. (1973) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(73)90072-2 · Cited by 65 · see citing works
Heart rate surges during REM sleep are associated with theta rhythm and PGO activity in cats
Rowe, K. A., Moreno, R., Lau, T. R., Wallooppillai, U., Nearing, B. D., Kocsis, B., Quattrochi, J. J., Hobson, J. A., & Verrier, R. L. (1999) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1999.277.3.r843 · Cited by 57 · see citing works
Nitz, D. A., & McNaughton, B. L. (1999) · Learning & Memory · doi:10.1101/lm.6.2.153 · Cited by 53 · see citing works
Lerma, J., & García-Austt, E. (1985) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(85)90950-2 · Cited by 52 · see citing works
Karashima, A., Nakao, M., Katayama, N., & Honda, K. (2005) · Brain Research · doi:10.1016/j.brainres.2005.05.055 · Cited by 51 · see citing works
Modulation of Hippocampal Theta Oscillation by Histamine H3 Receptors
Hajós, M., Siok, C. J., Hoffmann, W. E., Li, S., & Kocsis, B. (2007) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.130070 · Cited by 47 · see citing works
Mavanji, V., Ulloor, J., Saha, S. G., & Datta, S. (2004) · SLEEP · doi:10.1093/sleep/27.7.1282 · Cited by 45 · see citing works
The intermediate stage and paradoxical sleep in the rat: influence of three generations of hypnotics
Gottesmann, C., Gandolfo, G., Arnaud, C., & Gauthier, P. (1998) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1998.00069.x · Cited by 42 · see citing works
Histamine modulates reactivity of hippocampal CA3 neurons to afferent stimulation in vitro
Segal, M. (1981) · Brain Research · doi:10.1016/0006-8993(81)90251-1 · Cited by 38 · see citing works
Datta, S., Saha, S. G., Prutzman, S. L., Mullins, O. J., & Mavanji, V. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20501 · Cited by 37 · see citing works
Kocsis, B., Li, S., & Hajós, M. (2007) · Hippocampus · doi:10.1002/hipo.20299 · Cited by 37 · see citing works
Eye movements and hippocampal theta activity in rats
Sano, K., Iwahara, S., Senba, K., Sano, A., & Yamazaki, S. (1973) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(73)90215-0 · Cited by 33 · see citing works
Serotonergic modulation of carbachol-induced rhythmic activity in hippocampal slices
KRAUSE, M., & JIA, Y. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.10.011 · Cited by 30 · see citing works
The golden age of rapid eye movement sleep discoveries. 1. Lucretius—1964
Gottesmann, C. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(01)00014-4 · Cited by 29 · see citing works
A study of a possible "dreaming" mechanism in the cat.
Grastyán, E., & Karmos, G. (1961) · PubMed · Cited by 26 · see citing works
The Atonia And Myoclonia Of Active (Rem) Sleep
Chase, M. (1990) · Annual Review of Psychology · doi:10.1146/annurev.psych.41.1.557 · Cited by 19 · see citing works
Theta waves and behavioral manifestations of alertness and dreaming activity in the rat.
Valle, A. C., Timo-Iaria, C., Fraga, J. L., et al. (1992) · PubMed · Cited by 16 · see citing works
Eye Movements during Active and Passive Dreams
Berger, R. J., & Oswald, I. (1962) · Science · doi:10.1126/science.137.3530.601.a · Cited by 16 · see citing works
Toward an integrative theory of sleep and dreaming
Muzur, A. (2004) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2004.09.011 · Cited by 15 · see citing works
The Action of Serotonin in the Rat Hippocampus
Segal, M. (1981) · Advances in experimental medicine and biology · doi:10.1007/978-1-4684-3860-4_22 · Cited by 12 · see citing works
Effect of ambient temperature on arterial pressure variability during sleep in the rat
Séi, H., & Morita, Y. (1996) · Journal of Sleep Research · doi:10.1046/j.1365-2869.1996.00007.x · Cited by 10 · see citing works
A peculiar dreamlike stage of sleep in the cat.
Lissák, K., Karmos, G., & Grastyán, E. (1962) · PubMed · Cited by 4 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Thomson DJ, Chave AD (1991) Advances in spectrum analysis and array processing. In: Jackknifed error estimates for spectra, coherences, and transfer functions. Advances in spectrum analysis and array processing, pp 58 -113. New York: Prentice Hall.
Cited by
Sorted by citations
The origin of extracellular fields and currents — EEG, ECoG, LFP and spikes
Buzsáki, G., Anastassiou, C. A., & Koch, C. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3241 · Cited by 4,225 · see citing works
Self-citationDiekelmann, S., & Born, J. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2762 · Cited by 3,760 · see citing works
Rasch, B., & Born, J. (2013) · Physiological Reviews · doi:10.1152/physrev.00032.2012 · Cited by 2,783 · see citing works
Tononi, G., & Cirelli, C. (2014) · Neuron · doi:10.1016/j.neuron.2013.12.025 · Cited by 2,356 · see citing works
Neuronal gamma-band synchronization as a fundamental process in cortical computation
Fries, P. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135603 · Cited by 1,713 · see citing works
Control of sleep and wakefulness
Brown, R. E., Basheer, R., McKenna, J. T., Strecker, R. E., & McCarley, R. W. (2012) · Physiological Reviews · doi:10.1152/physrev.00032.2011 · Cited by 1,477 · see citing works
Cross-Frequency Phase–Phase Coupling between Theta and Gamma Oscillations in the Hippocampus
Belluscio, M. A., Mizuseki, K., Schmidt, R., Kempter, R., & Buzsáki, G. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.4122-11.2012 · Cited by 784 · see citing works
Mizuseki, K., Sirota, A., Pastalkova, E., & Buzsáki, G. (2009) · Neuron · doi:10.1016/j.neuron.2009.08.037 · Cited by 718 · see citing works
Self-citationRevealing neuronal function through microelectrode array recordings
Obien, M. E. J., Deligkaris, K., Bullmann, T., Bakkum, D. J., & Frey, U. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00423 · Cited by 705 · see citing works
Rhythms of the hippocampal network
Colgin, L. L. (2016) · Nature reviews. Neuroscience · doi:10.1038/nrn.2016.21 · Cited by 654 · see citing works
Mechanisms and functions of theta rhythms
Colgin, L. L. (2013) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062012-170330 · Cited by 559 · see citing works
Korotkova, T., Fuchs, E. C., Ponomarenko, A., von Engelhardt, J., & Monyer, H. (2010) · Neuron · doi:10.1016/j.neuron.2010.09.017 · Cited by 480 · see citing works
A 4 Hz oscillation adaptively synchronizes prefrontal, VTA, and hippocampal activities
Fujisawa, S., & Buzsáki, G. (2011) · Neuron · doi:10.1016/j.neuron.2011.08.018 · Cited by 501 · see citing works
Self-citationToroidal topology of population activity in grid cells
Gardner, R. J., Hermansen, E., Pachitariu, M., Burak, Y., Baas, N. A., Dunn, B. A., Moser, M.-B., & Moser, E. I. (2022) · Nature · doi:10.1038/s41586-021-04268-7 · Cited by 428 · see citing works
Human hippocampal theta oscillations and the formation of episodic memories
Lega, B. C., Jacobs, J., & Kahana, M. (2012) · Hippocampus · doi:10.1002/hipo.20937 · Cited by 485 · see citing works
Theta Phase Segregation of Input-Specific Gamma Patterns in Entorhinal-Hippocampal Networks
Schomburg, E. W., Fernández-Ruiz, A., Mizuseki, K., Berényi, A., Anastassiou, C. A., Koch, C., & Buzsáki, G. (2014) · Neuron · doi:10.1016/j.neuron.2014.08.051 · Cited by 465 · see citing works
REM sleep reorganizes hippocampal excitability
Grosmark, A. D., Mizuseki, K., Pastalkova, E., Diba, K., & Buzsáki, G. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.015 · Cited by 344 · see citing works
Brain neural patterns and the memory function of sleep
Girardeau, G., & Lopes-dos-Santos, V. (2021) · Science · doi:10.1126/science.abi8370 · Cited by 293 · see citing works
The role of REM sleep theta activity in emotional memory
Hutchison, I. C., & Rathore, S. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.01439 · Cited by 245 · see citing works
The Cell-Intrinsic Requirement of Sox6 for Cortical Interneuron Development
Batista-Brito, R., Rossignol, E., Hjerling-Leffler, J., Denaxa, M., Wegner, M., Lefebvre, V., Pachnis, V., & Fishell, G. (2009) · Neuron · doi:10.1016/j.neuron.2009.08.005 · Cited by 214 · see citing works
Virtual reality and consciousness inference in dreaming
Hobson, J. A., Hong, C. C.-H., & Friston, K. J. (2014) · Frontiers in Psychology · doi:10.3389/fpsyg.2014.01133 · Cited by 197 · see citing works
“Similarly, rat hippocampus shows increased gamma synchrony during phasic REM sleep, while gamma power and firing rates decrease during tonic REM sleep (Montgomery et al., 2008).”
BackgroundThe role of rapid eye movement sleep for amygdala-related memory processing
Genzel, L., Spoormaker, V. I., Konrad, B. N., & Dresler, M. (2015) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2015.01.008 · Cited by 161 · see citing works
The supramammillary nucleus and the claustrum activate the cortex during REM sleep
Renouard, L., Billwiller, F., Ogawa, K., Clément, O., Camargo, N., Abdelkarim, M., Gay, N., Scoté-Blachon, C., Touré, R., Libourel, P.-A., et al. (2015) · Science Advances · doi:10.1126/sciadv.1400177 · Cited by 152 · see citing works
Bergel, A., Deffieux, T., Demené, C., Tanter, M., & Cohen, I. (2018) · Nature Communications · doi:10.1038/s41467-018-07752-3 · Cited by 117 · see citing works
Non-circadian direct effects of light on sleep and alertness: Lessons from transgenic mouse models
Hubbard, J., Ruppert, E., Gropp, C.-M., & Bourgin, P. (2013) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2012.12.004 · Cited by 94 · see citing works
Prefrontal cortical regulation of REM sleep
Hong, J., Lozano, D. E., Beier, K. T., Chung, S., & Weber, F. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01398-1 · Cited by 83 · see citing works
Tononi, G., Boly, M., & Cirelli, C. (2024) · Neuron · doi:10.1016/j.neuron.2024.04.011 · Cited by 70 · see citing works
Lloret, M.-A., Cervera-Ferri, A., Nepomuceno, M., Monllor, P., Esteve, D., & Lloret, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21031168 · Cited by 68 · see citing works
Coupling of hippocampal theta and ripples with pontogeniculooccipital waves
Ramirez-Villegas, J. F., Besserve, M., Murayama, Y., Evrard, H. C., Oeltermann, A., & Logothetis, N. K. (2021) · Nature · doi:10.1038/s41586-020-2914-4 · Cited by 62 · see citing works
de Almeida-Filho, D. G., Koike, B. D. V., Billwiller, F., Farias, K. S., de Sales, I. R. P., Luppi, P.-H., Ribeiro, S., & Queiroz, C. M. (2021) · Scientific Reports · doi:10.1038/s41598-021-91659-5 · Cited by 56 · see citing works
Distinct features of fast oscillations in phasic and tonic rapid eye movement sleep
BRANKAČK, J., SCHEFFZÜK, C., KUKUSHKA, V. I., VYSSOTSKI, A. L., TORT, A. B. L., & DRAGUHN, A. (2012) · Journal of Sleep Research · doi:10.1111/j.1365-2869.2012.01037.x · Cited by 53 · see citing works
Rapid Eye Movement Sleep Sawtooth Waves Are Associated with Widespread Cortical Activations
Frauscher, B., von Ellenrieder, N., Dolezalova, I., Bouhadoun, S., Gotman, J., & Peter-Derex, L. (2020) · The Journal of Neuroscience · doi:10.1523/jneurosci.1586-20.2020 · Cited by 47 · see citing works
Dream to Predict? REM Dreaming as Prospective Coding
Llewellyn, S. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.01961 · Cited by 45 · see citing works
A new perspective on the functioning of the brain and the mechanisms behind conscious processes.
Keppler, J. (2013) · Frontiers in Psychology · doi:10.3389/fpsyg.2013.00242 · Cited by 37 · see citing works
Orzeł-Gryglewska, J., Matulewicz, P., & Jurkowlaniec, E. (2015) · Synapse · doi:10.1002/syn.21843 · Cited by 31 · see citing works
Sleep-dependent oscillatory synchronization: A role in fear memory consolidation
Totty, M. S., Chesney, L. A., Geist, P. A., & Datta, S. (2017) · Frontiers in Neural Circuits · doi:10.3389/fncir.2017.00049 · Cited by 29 · see citing works
Why Does Rem Sleep Occur? A Wake-Up Hypothesis1
Klemm, W. R. (2011) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2011.00073 · Cited by 27 · see citing works
Lu, H.-C., Pollack, H., Lefante, J. J., Mills, A. A., & Tian, D. (2019) · Sleep · doi:10.1093/sleep/zsy253 · Cited by 22 · see citing works
Llewellyn, S. (2016) · Consciousness and Cognition · doi:10.1016/j.concog.2016.09.018 · Cited by 17 · see citing works
To what extent do neurobiological sleep-waking processes support psychoanalysis?
Gottesmann, C. (2010) · International review of neurobiology · doi:10.1016/s0074-7742(10)92012-6 · Cited by 5 · see citing works
- Authors
- Montgomery, S. M., Sirota, A., & Buzsaki, G.
- Affiliations
- Rutgers, The State University of New Jersey (US)
- Venue
- Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2008-06-25
- Volume
- 28
- Issue
- 26
- Pages
- 6731-6741
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC2596978
- OpenAlex
- W2046203847
- Cited by
- 371
- References
- 98
- Citations by year
- 2026: 12 · 2025: 21 · 2024: 15 · 2023: 24 · 2022: 23 · 2021: 17 · 2020: 28 · 2019: 24 · 2018: 19 · 2017: 21 · 2016: 18 · 2015: 19 · 2014: 20 · 2013: 29 · 2012: 24
- FWCI
- 9.82
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Neuroscience (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation
- James S. McDonnell Foundation
- National Institutes of Health
- National Institute of Mental Health (R01MH054671, MH54671)
- National Institute of Neurological Disorders and Stroke (R01NS034994, NS-34994)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- REM sleep, hippocampal network, gamma synchrony, dentate gyrus, CA3, CA1, local field potentials, memory consolidation, hippocampal subfields
- MeSH terms
- Action Potentials, Animals, Biological Clocks, Exploratory Behavior, Hippocampus, Learning, Male, Motor Activity, Nerve Net, Neural Pathways, Synaptic Transmission, Neurons, Sleep, REM, Theta Rhythm, Wakefulness, Pyramidal Cells, Maze Learning, Dentate Gyrus, Rats, Long-Evans, Rats
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