Brca1 Controls Homology-Directed DNA Repair

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Centrosome Amplification and a Defective G2–M Cell Cycle Checkpoint Induce Genetic Instability in BRCA1 Exon 11 Isoform–Deficient Cells

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Tissue-Specific Carcinogens as Soil to Seed BRCA1/2-Mutant Hereditary Cancers

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BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1

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Reduced cell death, invasive and angiogenic features conferred by BRCA1-deficiency in mammary epithelial cells transformed with H-Ras

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Differential role of repair proteins, BRCA1/NBS1 and Ku70/DNA‐PKcs, in radiation‐induced centrosome overduplication

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PARP inhibitor reduces proliferation and increases apoptosis in breast cancer cells.

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DNA Strand Breaks in Mitotic Germ Cells of Caenorhabditis elegans Evaluated by Comet Assay

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Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage

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Recombination between Two Chromosomes: Implications for Genomic Integrity in Mammalian CellsPreprint

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Regulation of the Cell-Intrinsic DNA Damage Response by the Innate Immune Machinery

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Highly favorable outcome in BRCA-mutated metastatic breast cancer patients receiving high-dose chemotherapy and autologous hematopoietic stem cell transplantation

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Inadequate Rates of BRCA Testing with its Negative Consequences for Women with Epithelial Ovarian Cancer and their Families: an Overview of the Literature

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Checkpoint kinase‑1 inhibition and etoposide exhibit a strong synergistic anticancer effect on chronic myeloid leukemia cell line K562 by impairing homologous recombination DNA damage repair

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BARD1 Pathogenic Variants Are Associated with Triple-Negative Breast Cancer in a Spanish Hereditary Breast and Ovarian Cancer Cohort

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Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations

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Real-World Delivery of Rucaparib to Patients with Ovarian Cancer: Recommendations Based on an Integrated Safety Analysis of ARIEL2 and Study 10

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Dysfunctional BRCA1 is only indirectly linked to multiple centrosomes

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Caretaker Brca1: keeping the genome in the straight and narrow

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The role of the α-tubulin acetyltransferase αTAT1 in the DNA damage response

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BRCA1 Versus BRCA2 and PARP Inhibitors Efficacy in Solid Tumors:A Meta-Analysis of Randomized Controlled Trials

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Genetic testing in women with breast cancer: implications for treatment

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Biphasic recruitment of TRF2 to DNA damage sites promotes non-sister chromatid homologous recombination repair

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βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1

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Fine tuning chemotherapy to match BRCA1 status

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Targeting cancer-specific synthetic lethality in double-strand DNA break repair

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Mitotic delay in lymphocytes from BRCA1 heterozygotes unable to reduce the radiation-induced chromosomal damage

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Expression of an amino-terminal BRCA1 deletion mutant causes a dominant growth inhibition in MCF10A cells

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Interactions between BRCA Proteins and DNA Structure

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Transcription of a Donor Enhances Its Use during Double-Strand Break-Induced Gene Conversion in Human Cells

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Spontaneous homologous recombination is decreased in Rad51C-deficient hamster cells

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Differing effects of breast cancer 1, early onset (BRCA1) and ataxia‐telangiectasia mutated (ATM) mutations on cellular responses to ionizing radiation

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The Dawn of In Vivo Gene Editing Era: A Revolution in the Making

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Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells

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Genomic destabilization and its associated mutagenesis increase with senescence‐associated phenotype expression

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Cisplatin Affects the Conformation of Apo Form, not Holo Form, of BRCA1 RING Finger Domain and Confers Thermal Stability

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Tudor Domains as Methyl-Lysine and Methyl-Arginine Readers

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Highlight: BRCA1 and BRCA2 proteins in breast cancer

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Challenges in the Use of DNA Repair Deficiency As a Biomarker in Breast Cancer

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Is it time to split strategies to treat homologous recombinant deficiency in pancreas cancer?

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Homologous recombination in budding yeast expressing the human RAD52 gene reveals a Rad51-independent mechanism of conservative double-strand break repair

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Inherent and toxicant-provoked reduction in DNA repair capacity: A key mechanism for personalized risk assessment, cancer prevention and intervention, and response to therapy

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Mouse Models for Deciphering the Impact of Homologous Recombination on Tumorigenesis

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The fellowship of the RING: BRCA1, its partner BARD1 and their liaison in DNA repair and cancer

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p53 null Fluorescent Yellow Direct Repeat (FYDR) mice have normal levels of homologous recombination

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Radiosensibilité, radiocurabilité et réparation

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Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines

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DNA Damage Response Pathways and Cancer

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Interaction between DNA Polymerase β and BRCA1

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BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks

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Positioning loss of PARP1 activity as the central toxic event in BRCA-deficient cancer

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Integrating Cancer Vaccines in the Standard-of-Care of Ovarian Cancer: Translating Preclinical Models to Human

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“Recombomice”: The past, present, and future of recombination–detection in mice

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A Conditional Mouse Model for Measuring the Frequency of Homologous Recombination Events In Vivo in the Absence of Essential Genes

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Differences in 53BP1 and BRCA1 regulation between cycling and non-cycling cells

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Nuclear export of BRCA1 occurs during early S phase and is calcium-dependent

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The rate of extrachromosomal homologous recombination within a novel reporter plasmid is elevated in cells lacking functional ATM protein

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Absence of constitutional H2AX gene mutations in 101 hereditary breast cancer families

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Changing landscape of hematopoietic and mesenchymal cells and their interactions during aging and in age-related skeletal pathologies

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Ataxia–telangiectasia mutated coordinates the ovarian DNA repair and atresia-initiating response to phosphoramide mustard

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Protein stability versus function: effects of destabilizing missense mutations on BRCA1 DNA repair activity

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Loss of BRCA1-A Complex Function in RAP80 Null Tumor Cells

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The BRCA1 and BRCA2 Breast and Ovarian Cancer Susceptibility Genes — Implications for DNA Damage Response, DNA Repair and Cancer Therapy

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Regulation of cancer stem cells by RING finger ubiquitin ligases.

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Roles of DNA mutation in the coding region and DNA methylation in the 5′ flanking region of BRCA1 in canine mammary tumors

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A new bioinformatics tool to help assess the significance of BRCA1 variants

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BCL10 in cell survival after DNA damage

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The current state of molecular profiling in gastrointestinal malignancies

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BRCA2 Enters the Fray

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Downregulation of BRCA1 in A375 Melanoma Cell Line Increases Radio-Sensitivity and Modifies Metastatic and Angiogenic Gene Expression

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Homologous recombination deficiency and hemizygosity drive resistance in breast cancer

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New twist on BRCA1-mediated DNA recombination repair and tumor suppression

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Functional assessment of intrinsic disorder central domains of BRCA1

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Lengthening of high-yield production levels of monoclonal antibody-producing Chinese hamster ovary cells by downregulation of breast cancer 1

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CRL4-DCAF8L1 Regulates BRCA1 and BARD1 Protein Stability

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