The promise of minocycline in neurology

Inflammation is detrimental for neurogenesis in adult brain

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Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease

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Metalloproteinases in biology and pathology of the nervous system

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Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

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Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

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A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

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Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

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Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia

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Minocycline Prevents Nigrostriatal Dopaminergic Neurodegeneration in the MPTP Model of Parkinson’s Disease

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Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice

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Conversion of cytochrome c into a peroxidase: Inhibitory mechanisms and implication for neurodegenerative diseases

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Immunotherapies in Huntington's disease and α-Synucleinopathies

Fatoba, O., Ohtake, Y., Itokazu, T., & Yamashita, T. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00337 · Cited by 45

Neurovascular effects of CD47 signaling: Promotion of cell death, inflammation, and suppression of angiogenesis in brain endothelial cells in vitro

Xing, C., Lee, S.-R., Kim, W. J., Wang, H., Yang, Y., Ning, M., Wang, X., & Lo, E. H. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22076 · Cited by 43

Neuroprotective Interventions Targeting Detrimental Host Immune Responses Protect Mice From Fatal Alphavirus Encephalitis

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Inhibition of glioma growth by minocycline is mediated through endoplasmic reticulum stress-induced apoptosis and autophagic cell death

Liu, W.-T., Huang, C.-Y., Lu, I.-C., & Gean, P. (2013) · Neuro-Oncology · doi:10.1093/neuonc/not073 · Cited by 43

Minocycline mitigates the effect of neonatal hypoxic insult on human brain organoids

Boisvert, E. M., Means, R. E., Michaud, M., Madri, J. A., & Katz, S. G. (2019) · Cell Death & Disease · doi:10.1038/s41419-019-1553-x · Cited by 45

Protective effects of minocycline on experimental spinal cord injury in rats

Aras, M., Altaş, M., Motor, S., Dokuyucu, R., Yılmaz, A., Özgiray, E., Seraslan, Y., & Yılmaz, N. (2015) · Injury · doi:10.1016/j.injury.2015.05.018 · Cited by 42

Effective combination of human bone marrow mesenchymal stem cells and minocycline in experimental autoimmune encephalomyelitis mice

Hou, Y., Ryu, C. H., Park, K., Kim, S. M., Jeong, C., & Jeun, S. (2013) · Stem cell research & therapeutics · doi:10.1186/scrt228 · Cited by 44

Minocycline added to subcutaneous interferon β‐1a in multiple sclerosis: randomized RECYCLINE study

Sørensen, P. S., Sellebjerg, F. T., Lycke, J., Färkkilä, M. A., Créange, A., Lund, C., Schluep, M., Frederiksen, J. L., Stenager, E., Pfleger, C., et al. (2016) · European Journal of Neurology · doi:10.1111/ene.12953 · Cited by 42

Systemic Lipopolysaccharide-Induced Pain Sensitivity and Spinal Inflammation Were Reduced by Minocycline in Neonatal Rats

Hsieh, C.-T., Lee, Y., Dai, X., Ojeda, N. B., Lee, H. J., Tien, L., & Fan, L. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19102947 · Cited by 42

Administration of the glial cell modulator, minocycline, in the nucleus accumbens attenuated the maintenance and reinstatement of morphine-seeking behavior

Arezoomandan, R., & Haghparast, A. (2015) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2015-0209 · Cited by 41

Drug Repurposing to Target Neuroinflammation and Sensory Neuron-Dependent Pain

Sisignano, M., Gribbon, P. M., & Geißlinger, G. (2022) · Drugs · doi:10.1007/s40265-022-01689-0 · Cited by 42

Novel frontiers in epilepsy treatments: preventing epileptogenesis by targeting inflammation

D’Ambrosio, R., Eastman, C. L., Fattore, C., & Perucca, E. (2013) · Expert Review of Neurotherapeutics · doi:10.1586/ern.13.54 · Cited by 41

Minocycline Blocks Acute Bilirubin-Induced Neurological Dysfunction in Jaundiced Gunn Rats

Geiger, A. S., Rice, A. C., & Shapiro, S. M. (2007) · Neonatology · doi:10.1159/000103740 · Cited by 40

Multiple sclerosis – novel insights and new therapeutic strategies

Kieseier, B. C., Hemmer, B., & Hartung, H. (2005) · Current Opinion in Neurology · doi:10.1097/01.wco.0000169735.60922.fb · Cited by 39

Expression Profiling of Genes Modulated by Minocycline in a Rat Model of Neuropathic Pain

Rojewska, E., Korostyński, M., Przewłocki, R., Przewłocka, B., & Mika, J. (2014) · Molecular Pain · doi:10.1186/1744-8069-10-47 · Cited by 40

Microglial depletion under thalamic hemorrhage ameliorates mechanical allodynia and suppresses aberrant axonal sprouting

Hiraga, S.-I., Itokazu, T., Hoshiko, M., Takaya, H., Nishibe, M., & Yamashita, T. (2020) · JCI Insight · doi:10.1172/jci.insight.131801 · Cited by 40

The function of SUMOylation and its crucial roles in the development of neurological diseases

Chen, X., Zhang, Y., Wang, Q., Qin, Y., Yang, X., Xing, Z., Shen, Y., Wu, H., & Qi, Y. (2021) · The FASEB Journal · doi:10.1096/fj.202002702r · Cited by 39

Effects of rehabilitative training and anti-inflammatory treatment on functional recovery and cellular reorganization following stroke

Liebigt, S., Schlegel, N., Oberland, J., Witte, O. W., Redecker, C., & Keiner, S. (2011) · Experimental Neurology · doi:10.1016/j.expneurol.2011.11.037 · Cited by 39

Use of minocycline in viral infections.

Dutta, K., & Basu, A. (2011) · PubMed Central · Cited by 39

Effects of minocycline on Na+ currents in rat dorsal root ganglion neurons

Kim, T. H., Kim, H. I., Kim, J., Park, M., & Song, J.-H. (2010) · Brain Research · doi:10.1016/j.brainres.2010.11.038 · Cited by 38

Microglial inhibitory effect of ginseng ameliorates cognitive deficits and neuroinflammation following traumatic head injury in rats

Kumar, A., Rinwa, P., & Dhar, H. (2013) · Inflammopharmacology · doi:10.1007/s10787-013-0187-3 · Cited by 39

Experimental models of neuroprotection relevant to multiple sclerosis

Yong, V. W., Giuliani, F., Xue, M., Bar‐Or, A., & Metz, L. M. (2007) · Neurology · doi:10.1212/01.wnl.0000275230.20635.72 · Cited by 38

Impact of Minocycline on Extracellular Matrix Metalloproteinase Inducer, a Factor Implicated in Multiple Sclerosis Immunopathogenesis

Hahn, J. N., Kaushik, D. K., Mishra, M. K., Wang, J., Silva, C. G., & Yong, V. W. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1600436 · Cited by 37

Unexpected additive effects of minocycline and hydroxychloroquine in models of multiple sclerosis: Prospective combination treatment for progressive disease?

Faissner, S., Mahjoub, Y., Mishra, M. K., Haupeltshofer, S., Hahn, J. N., Gold, R., Koch, M. W., Metz, L. M., Ben‐Hur, T., & Yong, V. W. (2017) · Multiple Sclerosis Journal · doi:10.1177/1352458517728811 · Cited by 37

Recombinant Tissue Plasminogen Activator Enhances Microglial Cell Recruitment after Stroke in Mice

Lenglet, S., Montecucco, F., Dénes, Á., Coutts, G., Pinteaux, E., Mach, F., Schaller, K., Gasche, Y. G., & Copin, J. (2014) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2014.9 · Cited by 36

CNS and peripheral immunity in cerebral ischemia: partition and interaction

Kim, E., & Cho, S. (2020) · Experimental Neurology · doi:10.1016/j.expneurol.2020.113508 · Cited by 37

Social isolation–related depression accelerates ethanol intake via microglia-derived neuroinflammation

Lee, J., Lee, S.-B., Kim, D. W., Shin, N., Jeong, S.-J., Yang, C. H., & Son, C. (2021) · Science Advances · doi:10.1126/sciadv.abj3400 · Cited by 36

An emerging role of cGMP in the treatment of schizophrenia: A review

Shim, S. S., Shuman, M. D., & Duncan, E. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2015.11.015 · Cited by 35

Revisiting Minocycline in Intracerebral Hemorrhage: Mechanisms and Clinical Translation

Zhang, R., Yong, V. W., & Xue, M. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.844163 · Cited by 36

Prolonged Minocycline Treatment Impairs Motor Neuronal Survival and Glial Function in Organotypic Rat Spinal Cord Cultures

Pinkernelle, J., Fansa, H., Ebmeyer, U., & Keilhoff, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073422 · Cited by 37

Minocycline Modulates Human Social Decision-Making: Possible Impact of Microglia on Personality-Oriented Social Behaviors

Kato, T. A., Watabe, M., Tsuboi, S., Ishikawa, K., Hashiya, K., Monji, A., Utsumi, H., & Kanba, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040461 · Cited by 34

Tetracyclines cause cell stress-dependent ATF4 activation and mTOR inhibition

Brüning, A., Brem, G., Vogel, M., & Mylonas, I. G. (2013) · Experimental Cell Research · doi:10.1016/j.yexcr.2013.11.012 · Cited by 35

Effects of Minocycline on Hind-Limb Motor Function and Gray and White Matter Injury After Spinal Cord Ischemia in Rats

Takeda, M., Kawaguchi, M., Kumatoriya, T., Horiuchi, T., Watanabe, K., Inoue, S., Konishi, N., & Furuya, H. (2011) · Spine · doi:10.1097/brs.0b013e3181ffda29 · Cited by 35

Inhibiting effect of minocycline on the regeneration of peripheral nerves

Keilhoff, G., Langnaese, K., Wolf, G. L., & Fansa, H. (2007) · Developmental Neurobiology · doi:10.1002/dneu.20384 · Cited by 35

Multiple system atrophy: an update and emerging directions of biomarkers and clinical trials

Liu, M., Wang, Z., & Shang, H. (2024) · Journal of Neurology · doi:10.1007/s00415-024-12269-5 · Cited by 36

Molecular Mechanisms of Cell Death

Lemasters, J. J. (2009) · Elsevier eBooks · doi:10.1016/b978-0-12-374419-7.00001-9 · Cited by 37

Immunotherapy of Autoimmune Diseases with Nonantibiotic Properties of Tetracyclines

Park, C., Kim, S., & Lee, C. (2020) · Immune Network · doi:10.4110/in.2020.20.e47 · Cited by 34

Minocycline protects Schwann cells from ischemia-like injury and promotes axonal outgrowth in bioartificial nerve grafts lacking Wallerian degeneration

Keilhoff, G., Schild, L., & Fansa, H. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.03.028 · Cited by 34

A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia

Pérez‐Gómez, A., Carretero, M., Weber, N., Peterka, V., To, A., Titova, V., Solis, G. M., Osborn, O., & Petrascheck, M. (2018) · Nature Communications · doi:10.1038/s41467-018-07684-y · Cited by 35

Contribution of intraganglionic CGRP to migraine-like responses in male and female rats

Araya, E. I., Turnes, J. D. M., Barroso, A. R., & Chichorro, J. G. (2019) · Cephalalgia · doi:10.1177/0333102419896539 · Cited by 32

Minocycline, a possible neuroprotective agent in Leber’s hereditary optic neuropathy (LHON): Studies of cybrid cells bearing 11778 mutation

Haroon, M. F., Fatima, A., Schöler, S., Gieseler, A., Horn, T. F. W., Kirches, E., Wolf, G. L., & Kreutzmann, P. (2007) · Neurobiology of Disease · doi:10.1016/j.nbd.2007.07.021 · Cited by 33

Probing cytokines, chemokines and matrix metalloproteinases towards better immunotherapies of multiple sclerosis

Opdenakker, G., & Damme, J. V. (2011) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2011.11.005 · Cited by 33

Dual Modulation of ERK1/2 and p38 MAP Kinase Activities Induced by Minocycline Reverses the Neurotoxic Effects of the Prion Protein Fragment 90–231

Corsaro, A., Thellung, S., Chiovitti, K., Villa, V., Simi, A., Raggi, F., Paludi, D., Russo, C., Aceto, A., & Florio, T. (2009) · Neurotoxicity Research · doi:10.1007/s12640-009-9015-3 · Cited by 33

Organotypic Spinal Cord Culture: a Proper Platform for the Functional Screening

Pandamooz, S., Nabiuni, M., Miyan, J. A., Ahmadiani, A., & Dargahi, L. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9403-z · Cited by 34

Microglia and Autism Spectrum Disorder: Overview of Current Evidence and Novel Immunomodulatory Treatment Options

Kim, J. W., Hong, J. Y., & Bae, S. M. (2018) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2018.16.3.246 · Cited by 35

Anti-inflammatory and antiviral effects of minocycline in enterovirus 71 infections

Liao, Y.-T., Wang, S.-M., & Chen, S. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109271 · Cited by 32

Minocycline fails to protect cerebellar granular cell cultures against malonate-induced cell death

Fernández-Gómez, F.-J., Gómez-Lázaro, M., Pastor, M. D., Calvo, S., Aguirre, N., Galindo, M. F., & Jordán, J. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2005.03.019 · Cited by 32

A new approach for the investigation of reperfusion-related brain injury

Maier, C. M., Hsieh, L. B., Crandall, T., Narasimhan, P., & Chan, P. H. (2006) · Biochemical Society Transactions · doi:10.1042/bst0341366 · Cited by 32

Role of oxidative stress and caspase 3 in CD47‐mediated neuronal cell death

Xing, C., Lee, S.-R., Kim, W. J., Jin, G., Yang, Y., Ji, X., Wang, X., & Lo, E. H. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05777.x · Cited by 32

Minocycline as adjunctive treatment for major depressive disorder: Pooled data from two randomized controlled trials

Zazula, R., Husain, M. I., Mohebbi, M., Walker, A. J., Chaudhry, I. B., Khoso, A. B., Ashton, M. M., Agustini, B., Husain, N., Deakin, J., et al. (2021) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867420965697 · Cited by 31

Emerging Therapies for Relapsing Multiple Sclerosis

Cohen, J. A. (2009) · Archives of Neurology · doi:10.1001/archneurol.2009.104 · Cited by 31

Reversal of ultrasonic vocalization deficits in a mouse model of Fragile X Syndrome with minocycline treatment or genetic reduction of MMP-9

Toledo, M. A., Wen, T. H., Binder, D. K., Ethell, I. M., & Razak, K. A. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112068 · Cited by 31

Fish-oil supplementation decreases Indoleamine-2,3-Dioxygenase expression and increases hippocampal serotonin levels in the LPS depression model

Carabelli, B., Delattre, A. M., Waltrick, A. P. F., Araújo, G., Suchecki, D., Machado, R. B., de Souza, L. E. R., Zanata, S. M., Zanoveli, J. M., & Ferraz, A. C. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.112675 · Cited by 34

Minocycline inhibits sleep deprivation-induced aberrant microglial activation and Keap1-Nrf2 expression in mouse hippocampus

Ahmed, A., Misrani, A., Tabassum, S., Yang, L., & Long, C. (2021) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2021.05.028 · Cited by 32

3T deep gray matter T2 hypointensity correlates with disability over time in stable relapsing–remitting multiple sclerosis: A 3-year pilot study

Zhang, Y., Metz, L., Yong, V. W., & Mitchell, J. R. (2010) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2010.07.014 · Cited by 30

Fragile X syndrome: from gene discovery to therapy

Heulens, I. (2010) · Frontiers in bioscience · doi:10.2741/3785 · Cited by 32

Combined treatment with minocycline and prednisone attenuates experimental autoimmune encephalomyelitis in C57 BL/6 mice

Chen, X., Hu, X., Zou, Y., Pi, R., Liu, M., Wang, T., Zheng, X., Liu, M., Lin, M., Liu, P., et al. (2009) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2009.02.016 · Cited by 31

NANOCARRIERS FOR TARGETING IN INFLAMMATION

Shaji, J., & Lal, M. (2013) · Asian Journal of Pharmaceutical and Clinical Research · Cited by 31

Cerebrospinal Fluid Biomarkers in Human Spinal Cord Injury from a Phase II Minocycline Trial

Casha, S., Rice, T. K., Stirling, D. P., Silva, C., Gnanapavan, S., Giovannoni, G., Hurlbert, R. J., & Yong, V. W. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2018.5899 · Cited by 31

Minocycline Ameliorates Chronic Unpredictable Mild Stress-Induced Neuroinflammation and Abnormal mPFC-HIPP Oscillations in Mice

Tabassum, S., Misrani, A., Huo, Q., Ahmed, A., Long, C., & Yang, L. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-03018-8 · Cited by 30

Role of microglia and toll-like receptor 4 in the pathophysiology of delirium

Jalleh, R. J., KOH, K. S. B., Choi, B., Liu, E., Maddison, J., & Hutchinson, M. R. (2012) · Medical Hypotheses · doi:10.1016/j.mehy.2012.08.013 · Cited by 31

Chemokines and Their Receptors in Intracerebral Hemorrhage

Yao, Y., & Tsirka, S. E. (2012) · Translational Stroke Research · doi:10.1007/s12975-012-0155-z · Cited by 32

Neuroinflammatory Proteins in Huntington’s Disease: Insights into Mechanisms, Diagnosis, and Therapeutic Implications

Li, X., Tong, H., Xu, S., Zhou, G., Yang, T., Yin, S., Yang, S., Li, X., & Li, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252111787 · Cited by 35

Prevention of microgliosis halts early memory loss in a mouse model of Alzheimer’s disease

Kater, M. S. J., Huffels, C. F. M., Oshima, T., Renckens, N. S., Middeldorp, J., Boddeke, E., Smit, A. B., Eggen, B. J. L., Hol, E. M., & Verheijen, M. H. G. (2022) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2022.10.009 · Cited by 30

Herpes simplex encephalitis is linked with selective mitochondrial damage; a post-mortem and in vitro study

Wnęk, M., Ressel, L., Ricci, E., Rodriguez-Martinez, C., Guerrero, J. C. V., Ismail, Z., Smith, C., Kipar, A., Sodeik, B., Chinnery, P. F., et al. (2016) · Acta Neuropathologica · doi:10.1007/s00401-016-1597-2 · Cited by 29

Emerging chemotherapeutic strategies for Huntington’s disease

Ryu, H., & Ferrante, R. J. (2005) · Expert Opinion on Emerging Drugs · doi:10.1517/14728214.10.2.345 · Cited by 30

Oral Disease-Modifying Treatments for Multiple Sclerosis

Kieseier, B. C., & Wiendl, H. (2007) · CNS Drugs · doi:10.2165/00023210-200721060-00005 · Cited by 29

Differences in microglia morphological profiles reflect divergent emotional temperaments: insights from a selective breeding model

Maras, P. M., Hebda-Bauer, E. K., Hagenauer, M. H., Hilde, K. L., Blandino, P., Watson, S. J., & Akil, H. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01821-4 · Cited by 26

Minocycline prevents neuronal hyperexcitability and neuroinflammation in medial prefrontal cortex, as well as memory impairment caused by repeated toluene inhalation in adolescent rats

Cruz, S. L., Armenta-Reséndiz, M., Carranza‐Aguilar, C. J., & Galván, E. J. (2020) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2020.114980 · Cited by 28

Minocycline treatment increases resistance to oxidative stress and extends lifespan in Drosophila via FOXO

Lee, G. J., Lim, J. J., & Hyun, S. (2017) · Oncotarget · doi:10.18632/oncotarget.21224 · Cited by 28

Therapeutic Approaches to Multiple Sclerosis

Ulzheimer, J. C., Meuth, S. G., Bittner, S., Kleinschnitz, C., Kieseier, B. C., & Wiendl, H. (2010) · BioDrugs · doi:10.2165/11537160-000000000-00000 · Cited by 27

Minocycline treatment prevents cavitation in rats after a cortical devascularizing lesion

Hua, R., & Walz, W. (2006) · Brain Research · doi:10.1016/j.brainres.2006.03.072 · Cited by 27

Minocycline mitigates the gliogenic effects of proinflammatory cytokines on neural stem cells

Vay, S. U., Blaschke, S. J., Klein, R. M., Fink, G. R., Schroeter, M., & Rueger, M. A. (2015) · Journal of Neuroscience Research · doi:10.1002/jnr.23686 · Cited by 26

The Role of Oligodendrocytes in the Molecular Pathobiology and Potential Molecular Treatment of Cervical Spondylotic Myelopathy

Karadimas, S. K., Gialeli, C., Klironomos, G., Tzanakakis, G. N., Panagiotopoulos, E. C., Karamanos, N. K., & Gatzounis, G. D. (2010) · Current Medicinal Chemistry · doi:10.2174/092986710790820598 · Cited by 29

UBE3A regulates the transcription of IRF, an antiviral immunity

Furumai, R., Tamada, K., Liu, X., & Takumi, T. (2019) · Human Molecular Genetics · doi:10.1093/hmg/ddz019 · Cited by 26

Minocycline protects against microgliopathy in a Csf1r haplo-insufficient mouse model of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP)

Li, X., Hu, B., Xiaoyan, G., Wang, Z., Zhou, Y., Sun, H., Zhang, X., Li, Y., Huang, X., Zhao, Y., et al. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02774-1 · Cited by 25

Treatment of children and adolescents with multiple sclerosis

Banwell, B. (2005) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.5.3.391 · Cited by 26

Further understanding of the immunopathology of multiple sclerosis: impact on future treatments

Bhise, V. V., & Dhib-Jalbut, S. S. (2016) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2016.1191351 · Cited by 28

Antifungal Activity of Minocycline and Azoles Against Fluconazole-Resistant Candida Species

Tan, J., Jiang, S., Tan, L., Shi, H., Yang, L., Sun, Y., & Wang, X. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.649026 · Cited by 28

Combination therapies

Oudega, M., Bradbury, E. J., & Ramer, M. S. (2012) · Handbook of clinical neurology · doi:10.1016/b978-0-444-52137-8.00038-3 · Cited by 25

Enhanced biocompatibility of neural probes by integrating microstructures and delivering anti-inflammatory agents via microfluidic channels

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Changes of Blood–Brain Barrier Permeability Following Intracerebral Hemorrhage and the Therapeutic Effect of Minocycline in Rats

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