The promise of minocycline in neurology

Inflammation is detrimental for neurogenesis in adult brain

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Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease

Wu, D. C., Jackson-Lewis, V., Vila, M., Tieu, K., Teismann, P., Vadseth, C., Choi, D.-K., Ischiropoulos, H., & Przedborski, S. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-05-01763.2002 · Cited by 1,183

Metalloproteinases in biology and pathology of the nervous system

Yong, W. V., Power, C., Forsyth, P., & Edwards, D. (2001) · Nature Reviews Neuroscience · doi:10.1038/35081571 · Cited by 1,094

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

Zhu, S., Stavrovskaya, I. G., Drozda, M., Kim, B. Y. S., Ona, V. O., Li, M., Sarang, S. S., Liu, A. S., Hartley, D. M., Wu, D. C., et al. (2002) · Nature · doi:10.1038/417074a · Cited by 1,069

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

Chen, M., Ona, V. O., Li, M., Ferrante, R. J., Fink, K., Zhu, S., Bian, J., Guo, L., Farrell, L. A., Hersch, S. M., et al. (2000) · Nature Medicine · doi:10.1038/77528 · Cited by 1,060

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

Yrjänheikki, J., Kauppinen, T. M., Keinänen, R., Goldsteins, G., Chan, P. H., & Koıstınaho, J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13496 · Cited by 1,040

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

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Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia

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Minocycline Prevents Nigrostriatal Dopaminergic Neurodegeneration in the MPTP Model of Parkinson’s Disease

Du, Y., Ma, Z., Lin, S., Dodel, R. C., Gao, F., Bales, K. R., Triarhou, L. C., Chernet, E., Perry, K. W., Nelson, D. L. G., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.251341998 · Cited by 789

Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice

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Minocycline Inhibits ICAD Degradation and the NF-ΚB Activation Induced by 6-OHDA in PC12 Cells

Jiang, B.-P., Le, L., Xu, L.-J., & Xiao, P.-G. (2014) · Brain Research · doi:10.1016/j.brainres.2014.08.001 · Cited by 19

Minocycline Attenuates Lipopolysaccharide-Induced Locomotor Deficit and Anxiety-like Behavior and Related Expression of the BDNF/CREB Protein in the Rat Medial Prefrontal Cortex (mPFC)

Qaid, E. Y. A., Abdullah, Z., Zakaria, R., & Long, I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113474 · Cited by 18

Combination of methylprednisolone and minocycline synergistically improves experimental autoimmune encephalomyelitis in C57 BL/6 mice

Chen, X., Pi, R., Liu, M., Ma, X., Jiang, Y., Liu, Y., Mao, X., & Hu, X. (2010) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.05.039 · Cited by 20

Stress-Induced NLRP3 Inflammasome in Human Diseases

Alcocer‐Gómez, E., Castejón‐Vega, B., & Cordero, M. D. (2017) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2017.02.002 · Cited by 19

Therapeutic Effects of Minocycline Pretreatment in the Locomotor and Sensory Complications of Spinal Cord Injury in an Animal Model

Afshary, K., Chamanara, M., Talari, B., Rezaei, P., & Nassireslami, E. (2020) · Journal of Molecular Neuroscience · doi:10.1007/s12031-020-01509-8 · Cited by 20

Minocycline impedes mitochondrial-dependent cell death and stabilizes expression of hypoxia inducible factor-1α in spinal cord injury

Zhang, G., Zha, J., Liu, J., & Di, J. (2018) · Archives of Medical Science · doi:10.5114/aoms.2018.73520 · Cited by 20

Advances in Neuropathic Pain Research: Selected Intracellular Factors as Potential Targets for Multidirectional Analgesics

Ciapała, K., & Mika, J. (2023) · Pharmaceuticals · doi:10.3390/ph16111624 · Cited by 20

The efficacy of minocycline against methotrexate-induced pulmonary fibrosis in mice.

Kalemci, S., Dirican, N., Çetin, E. S., Sözen, H., Üner, A. G., Yaylalı, A., Aksun, S., Karaçam, V., Ulger, E., Sütçü, R., et al. (2013) · PubMed · Cited by 19

Minocycline prevents cerebral malaria, confers neuroprotection and increases survivability of mice during Plasmodium berghei ANKA infection

Apoorv, T. S., & Babu, P. P. (2016) · Cytokine · doi:10.1016/j.cyto.2016.11.001 · Cited by 19

Sumatriptan improves the locomotor activity and neuropathic pain by modulating neuroinflammation in rat model of spinal cord injury

Afshari, K., Dehdashtian, A., Haddad, N.-S., Jazaeri, S. Z., Ursu, D. C., Khalilzadeh, M., Haj‐Mirzaian, A., Shakiba, S., Burns, T. C., Tavangar, S. M., et al. (2020) · Neurological Research · doi:10.1080/01616412.2020.1819090 · Cited by 19

Minocycline attenuation of rat corpus callosum abnormality mediated by low-dose lipopolysaccharide-induced microglia activation

Zhang, J., Boska, M. D., Zheng, Y., Liu, J., Fox, H. S., & Xiong, H. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02142-x · Cited by 19

Minocycline and cisplatin exert synergistic growth suppression on hepatocellular carcinoma by inducing S phase arrest and apoptosis

Liu, F., WU, A.-H., Zhou, S.-J., Deng, Y.-L., Zhang, Z.-Y., Zhang, E.-L., & Huang, Z. (2014) · Oncology Reports · doi:10.3892/or.2014.3248 · Cited by 19

Interferon β-secreting mesenchymal stem cells combined with minocycline attenuate experimental autoimmune encephalomyelitis

Hou, Y., Ryu, C. H., Jun, J. A., Kim, S. M., Jeong, C. H., & Jeun, S. (2014) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2014.06.001 · Cited by 19

Bilirubin-induced neurological damage

Gazzin, S., & Tiribelli, C. (2011) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2011.607590 · Cited by 19

Local Vasogenic Edema without Cerebral Hyperperfusion after Direct Revascularization Surgery for Moyamoya Disease

Sakata, H., Fujimura, M., Mugikura, S., Sato, K., & Tominaga, T. (2015) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2015.03.050 · Cited by 19

Zaprinast diminished pain and enhanced opioid analgesia in a rat neuropathic pain model

Rojewska, E., Piotrowska, A., Jurga, A. M., Makuch, W., & Mika, J. (2018) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2018.09.001 · Cited by 18

The Effect of Minocycline on Fat Graft Survival and Apoptotic Pathway

Güney, K., Özel, B., Seymen, C. M., Elmas, Ç., Tuncer, S., Çenetoğlu, S., & Tatar, S. (2019) · Facial Plastic Surgery · doi:10.1055/s-0039-1677709 · Cited by 18

A randomized placebo controlled clinical trial to evaluate the efficacy and safety of minocycline in patients with Angelman syndrome (A-MANECE study)

Ruíz‐Antorán, B., Sancho‐López, A., Cazorla-Calleja, R., López-Pájaro, L. F., Leiva, Á., Escalera, G. I., Marín-Serrano, M. E., Rincón-Ortega, M., Herguedas, J. L., Rossignoli-Palomeque, T., et al. (2018) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-018-0891-6 · Cited by 18

Curcumin Prevents Cerebellar Hypoplasia and Restores the Behavior in Hyperbilirubinemic Gunn Rat by a Pleiotropic Effect on the Molecular Effectors of Brain Damage

Gazzin, S., Ben, M. D., Montrone, M., Jayanti, S. D., Lorenzon, A., Bramante, A., Bottin, C., Moretti, R., & Tiribelli, C. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010299 · Cited by 18

Flow-augmentation bypass for moyamoya disease

Fujimura, M., & Tominaga, T. (2021) · Journal of Neurosurgical Sciences · doi:10.23736/s0390-5616.20.05079-1 · Cited by 17

Blue Light Induces RPE Cell Necroptosis, Which Can Be Inhibited by Minocycline

Song, W., Zhu, R., Gao, W., Chen, X., & Yang, L. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.831463 · Cited by 17

Minocycline Treatment Improves Cognitive and Functional Plasticity in a Preclinical Mouse Model of Major Depressive Disorder

Poggini, S., Banqueri, M., Albanese, N. C., Golia, M. T., Ibáñez, F. G., Limatola, C., Fuhrmann, M., Lalowski, M. M., Tremblay, M., Maggi, L., et al. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114295 · Cited by 18

Inhibition of brain retinoic acid catabolism: a mechanism for minocycline's pleiotropic actions?

Regen, F., Bret, N. L., Hildebrand, M., Herzog, I., Heuser, I., & Hellmann‐Regen, J. (2015) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2015.1036116 · Cited by 20

Minocycline Promotes Neurite Outgrowth of PC12 Cells Exposed to Oxygen-Glucose Deprivation and Reoxygenation Through Regulation of MLCP/MLC Signaling Pathways

Tao, T., Feng, J., Xu, G., Fu, J., Li, X., & Qin, X. (2016) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-016-0374-z · Cited by 17

Development of Complete Thoracic Spinal Cord Transection Model in Rats for Delayed Transplantation of Stem Cells

Min, S. H., Lee, S. H., Shim, H., Park, J., Lee, Y. I., Kim, H., & Hyun, J. K. (2010) · Spine · doi:10.1097/brs.0b013e3181d8b92a · Cited by 16

Minocycline promotes the generation of dendritic cells with regulatory properties

Kim, N., Park, C., Im, S., Kim, J.-W., Lee, J., Park, Y.-J., Song, S., & Lee, C. (2016) · Oncotarget · doi:10.18632/oncotarget.10810 · Cited by 16

Minocycline attenuates interferon-α-induced impairments in rat fear extinction

Bi, Q., Shi, L., Yang, P., Wang, J., & Qin, L. (2016) · Journal of Neuroinflammation · doi:10.1186/s12974-016-0638-z · Cited by 18

Minocycline exerts acute inhibitory effects on cerebral cortex excitability in humans

Lang, N., Rothkegel, H., Terney, D., Antal, A., & Paulus, W. (2013) · Epilepsy Research · doi:10.1016/j.eplepsyres.2013.09.006 · Cited by 15

Sleep Deprivation Induces Dopamine System Maladaptation and Escalated Corticotrophin-Releasing Factor Signaling in Adolescent Mice

Tuan, L., Yeh, J.-W., Lee, L. J., & Lee, L. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03258-2 · Cited by 17

Current Advances in Japanese Encephalitis Virus Drug Development

Guo, J., Mi, Y., Guo, Y. Q., Bai, Y., Wang, M., Wang, W., & Wang, Y. (2024) · Viruses · doi:10.3390/v16020202 · Cited by 15

Therapeutic strategies that modulate the acute phase of secondary spinal cord injury scarring and inflammation and improve injury outcomes

Migliorini, F., Pilone, M., Eschweiler, J., Katusić, D., Memminger, M. K., & Maffulli, N. (2025) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2025.2470326 · Cited by 15

Neuroprotective effect of minocycline on rat retinal ischemia-reperfusion injury.

Li, X., Ye, Z., Pei, S., Zheng, D., & Zhu, L. (2021) · PubMed Central · Cited by 15

Should preventive antibiotics be used in patients with acute stroke? A systematic review and meta-analysis of randomized controlled trials

Zheng, F., von Spreckelsen, N., Zhang, X., Stavrinou, P. C., Timmer, M., Dohmen, C., Goldbrunner, R., Cao, F., Zhang, Q., Ran, Q., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0186607 · Cited by 15

The trials and errors in MS therapy.

Kleinschnitz, C., Meuth, S. G., & Wiendl, H. (2008) · PubMed · Cited by 15

Intestinal injury and changes of the gut microbiota after ischemic stroke

Shen, Y., Wang, J. A., Li, Y., Kang, X., & Gu, L. (2025) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2025.1557746 · Cited by 15

Oral Minocycline Therapy Improves Symptoms of Myalgic Encephalomyelitis, Especially in the Initial Disease Stage

Miwa, K. (2021) · Internal Medicine · doi:10.2169/internalmedicine.6082-20 · Cited by 14

Immunological Biomarkers as Predictors of Treatment Response in Psychotic Disorders

Orbe, E. B., & Benros, M. E. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13091382 · Cited by 17

Comparative Therapeutic Effects of Minocycline Treatment and Bone Marrow Mononuclear Cell Transplantation following Striatal Stroke

de Souza, C. C., da Silva, M. C., Afonso, R. T. L., Cardoso, M. M., de Souza, L. L., Santos, A. G., Santos, I. R., Franco, E. C. S., & Gomes‐Leal, W. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/1976191 · Cited by 14

CASP-9: A susceptibility locus for multiple sclerosis in Italy

Andreoli, V., Trecroci, F., Russa, A. L., Valentino, P., Condino, F., Latorre, V., Nisticò, R., Pirritano, D., Giudice, F. D., Canino, M., et al. (2009) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2009.03.013 · Cited by 13

Molecular mechanisms and treatment strategies for methamphetamine‑induced neurodegeneration, inflammation and neurotoxicity

Omidvari, S., Azimzadeh, Z., Rashnoo, F., Tahmasebinia, F., Keramatinia, A., Roozbahany, N. A., Abbaszadeh, H., & Darabi, S. (2023) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2023-2488 · Cited by 15

Minocycline‐induced dermatomyositis

Geddes, M. R., Sinnreich, M., & Chalk, C. (2010) · Muscle & Nerve · doi:10.1002/mus.21487 · Cited by 13

Striking Growth-inhibitory Effects of Minocycline on Human Prostate Cancer Cell Lines

Regen, F., Heuser, I., Herzog, I., & Hellmann‐Regen, J. (2013) · Urology · doi:10.1016/j.urology.2013.10.029 · Cited by 13

Minocycline treatment improves proteostasis during Drosophila aging via autophagy mediated by FOXO and Hsp70

Lim, J. J., & Hyun, S. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.112803 · Cited by 16

Minocycline enhances inhibitory transmission to substantia gelatinosa neurons of the rat spinal dorsal horn

Peng, H., Ma, L., Lv, M.-H., Hu, T., & Liu, T. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.01.047 · Cited by 13

Surface functionalization of TiO2 nanotubes with minocycline and its in vitro biological effects on Schwann cells

Lan, A., Xu, W., Zhao, J., Li, C., Qi, M., Li, X., Wang, L., & Zhou, Y. (2018) · BioMedical Engineering OnLine · doi:10.1186/s12938-018-0520-6 · Cited by 13

Mitochondria, oxidative stress and PARP‐1 network: a new target for neuroprotective effects of tetracyclines?

Orsucci, D., Mancuso, M., & Siciliano, G. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.152819 · Cited by 13

Strategies for regenerating injured axons after spinal cord injury – insights from brain development

Yamashita, T. (2008) · Biologics · doi:10.2147/btt.s2715 · Cited by 13

Immunomodulatory drug treatment in multiple sclerosis

Aharoni, R. (2010) · Expert Review of Neurotherapeutics · doi:10.1586/ern.10.117 · Cited by 13

Minocycline Prevents Muscular Pain Hypersensitivity and Cutaneous Allodynia Produced by Repeated Intramuscular Injections of Hypertonic Saline in Healthy Human Participants

Samour, M. S., Nagi, S. S., Shortland, P. J., & Mahns, D. A. (2017) · Journal of Pain · doi:10.1016/j.jpain.2017.03.009 · Cited by 12

Minocycline reduces oxygen–glucose deprivation-induced PC12 cell cytotoxicity via matrix metalloproteinase-9, integrin β1 and phosphorylated Akt modulation

Chen, X., Chen, S., Jiang, Y., Zhu, C., Wu, A., Ma, X., Peng, F., Ma, L., Zhu, D., Wang, Q., et al. (2012) · Neurological Sciences · doi:10.1007/s10072-012-1246-z · Cited by 12

Minocycline potentiates the anti-hyperalgesic effect of ceftriaxone in CCI-induced neuropathic pain in rats.

Amin, B., Hajhashemi, V., & Hosseinzadeh, H. (2015) · Europe PMC (PubMed Central) · Cited by 12

Minocycline delays but does not attenuate the course of experimental autoimmune encephalomyelitis in Streptococcus pneumoniae-infected mice

Herrmann, I., Kellert, M., Spreer, A., Gerber, J., Eiffert, H., Prinz, M., & Nau, R. (2006) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkl446 · Cited by 12

Minocycline treatment suppresses juvenile development and growth by attenuating insulin/TOR signaling in Drosophila animal model

Yun, H. M., Noh, S., & Hyun, S. (2017) · Scientific Reports · doi:10.1038/srep44724 · Cited by 11

Anti-inflammatory Approaches to Mitigate the Neuroinflammatory Response to Brain-Dwelling Intracortical Microelectrodes

Capadona, J. R. (2018) · Journal of Immunological Sciences · doi:10.29245/2578-3009/2018/4.1157 · Cited by 11

Mechanisms of multiple sclerosis

Lassmann, H. (2005) · Drug Discovery Today Disease Mechanisms · doi:10.1016/j.ddmec.2005.11.007 · Cited by 14

Simple Liquid Chromatographic Determination of Minocycline in Brain and Plasma

Milane, A., Fernandez, C., Bensimon, G., Meininger, V., & Farinotti, R. (2007) · Chromatographia · doi:10.1365/s10337-006-0167-5 · Cited by 11

Synapse Regulation

Vecchiarelli, H. A., Lopes, L. T., Paolicelli, R. C., Stevens, B., Wake, H., & Tremblay, M. (2024) · Advances in neurobiology · doi:10.1007/978-3-031-55529-9_11 · Cited by 10

Minocycline reduces experimental muscle hyperalgesia induced by repeated nerve growth factor injections in humans: A placebo‐controlled double‐blind drug‐crossover study

Dunn, J. S., Nagi, S. S., & Mahns, D. A. (2020) · European Journal of Pain · doi:10.1002/ejp.1558 · Cited by 10

Effects of minocycline on dendrites, dendritic spines, and microglia in immature mouse brains after kainic acid‐induced status epilepticus

Yang, X., Li, T., Liu, J., Sun, H. B., Cheng, L., Song, X., Han, Z., Luo, H., Han, W., Xie, L., et al. (2023) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14352 · Cited by 10

Systemic minocycline differentially influences changes in spinal microglial markers following formalin-induced nociception

Li, K., Fu, K., Light, A. R., & Mao, J. (2010) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.02.003 · Cited by 10

Using magnetic resonance imaging in animal models to guide drug development in multiple sclerosis

Nathoo, N., Yong, V. W., & Dunn, J. F. (2013) · Multiple Sclerosis Journal · doi:10.1177/1352458513512709 · Cited by 10

Minocycline increases firing rates of accumbal neurons and modifies the effects of morphine on neuronal activity

Arezoomandan, R., Riahi, E., & Haghparast, A. (2017) · Addiction Biology · doi:10.1111/adb.12557 · Cited by 10

Influence of lipopolysaccharide on diazepam-modified loss of righting reflex duration by pentobarbital treatment in mice

Kitamura, Y., Hongo, S., Yamashita, Y., Yagi, S., Otsuki, K., Miki, A., Okada, A., Ushio, S., Esumi, S., & Sendo, T. (2018) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2018.10.049 · Cited by 12

Successful Use of Minocycline for the Treatment of Methamphetamine-Induced Psychosis and Cognitive Impairments: An Open-Label Case Series

Alavi, S., Darharaj, M., Bilehsavar, S. H., Amini, M., Zafarghandi, M. B. S., Berenji, V., & Arezoomandan, R. (2021) · Clinical Neuropharmacology · doi:10.1097/wnf.0000000000000460 · Cited by 10

The Role of Concomitant Nrf2 Targeting and Stem Cell Therapy in Cerebrovascular Disease

Gordon, J., Lockard, G., Monsour, M., Alayli, A., & Borlongan, C. V. (2022) · Antioxidants · doi:10.3390/antiox11081447 · Cited by 11

Is minocycline useful for therapy of acute viral encephalitis?

Jackson, A. C. (2012) · Antiviral Research · doi:10.1016/j.antiviral.2012.06.005 · Cited by 10

Minocycline for axonal regeneration after nerve injury: A double-edged sword

Casha, S., Yong, V. W., & Midha, R. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.06.016 · Cited by 10

[Minocycline for the treatment of amyotrophic lateral sclerosis: neuroprotector or neurotoxin? Reflections on another failure of translational medicine].

Gámez, J. (2008) · PubMed · Cited by 10

Novel therapeutic modulators of astrocytes for hydrocephalus

Yang, Y., Wang, C., Chen, R., Wang, Y.-C., Tan, C., Liu, J., Zhang, Q., & Xiao, G. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.932955 · Cited by 10

Minocycline as a potential anxiolytic drug: systematic review and meta-analysis of evidence in murine models

Iglesias, L. P., Soares, N., Asth, L., Moreira, F. A., & de Aguiar, D. C. (2023) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000754 · Cited by 8

Discovery of novel protective agents for infection-related delirium through bispectral electroencephalography

Nishiguchi, T., Yamanishi, K., Patel, S. S., Malicoat, J. R., Phuong, N. J., Seki, T., Ishii, T., Aoyama, B., Shimura, A., Gorantla, N., et al. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03130-4 · Cited by 9

Bumetanide prevents diazepam-modified anxiety-like behavior in lipopolysaccharide-treated mice

Matsumoto, D., Ushio, S., Wada, Y., Noda, Y., Esumi, S., Izushi, Y., Kitamura, Y., & Sendo, T. (2021) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2021.174195 · Cited by 12

Recombinant Human Prion Protein Fragment 90–231, a Useful Model to Study Prion Neurotoxicity

Corsaro, A., Thellung, S., Villa, V., Nizzari, M., Aceto, A., & Florio, T. (2012) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2011.0038 · Cited by 9

Immune Modulatory Treatments for Autism Spectrum Disorder

Thom, R. P., & McDougle, C. J. (2020) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2020.100836 · Cited by 9

Update on huntington’s disease

Berman, S. B., & Greenamyre, J. T. (2006) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-006-0019-6 · Cited by 9

Managing Overly Rapid Correction of Chronic Hyponatremia

Kamel, K. S., & Halperin, M. L. (2010) · Journal of the American Society of Nephrology · doi:10.1681/asn.2010101062 · Cited by 9

Is it possible to prevent excessive synaptic pruning in schizophrenia? Possibilities and limitations

Pawlak, A., Stefanowicz, J., Kotkowska, Z., Gabryelska, A., Sochal, M., Napieraj, F., Kotlicka‐Antczak, M., & Strzelecki, D. (2025) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2025.1656232 · Cited by 9

The role of MMPs in intracerebral hemorrhage

Guan, X., Li, M., Li, H., Guo, Z., Ullah, M. S., Liu, X., Wu, M., & Yu, W. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1667228 · Cited by 8

Combined treatment with Minocycline and methylprednisolone in acute traumatic spinal cord Injury: A pilot study

Meshkini, A., Ohadi, M. A. D., Mirghaderi, P., Mirzaei, F., Rafiei, E., Allahyari, N., Namvar, M., & Iranmehr, A. (2023) · Interdisciplinary Neurosurgery · doi:10.1016/j.inat.2023.101883 · Cited by 8

Advances in Stroke

Planas, A. M. (2013) · Stroke · doi:10.1161/strokeaha.111.000495 · Cited by 8

Minocycline encapsulated chitosan nanoparticles for central antinociceptive activity

Nagpal, K., Singh, S. K., & Mishra, D. N. (2014) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2014.07.055 · Cited by 8

Antibiotics with therapeutic effects on spinal cord injury: a review

Afshari, K., Roudsari, N. M., Lashgari, N., Haddadi, N., Haj‐Mirzaian, A., Nejad, M. H., Shafaroodi, H., Ghasemi, M., Dehpour, A. R., & Abdolghaffari, A. H. (2020) · Fundamental and Clinical Pharmacology · doi:10.1111/fcp.12605 · Cited by 10

Management of Intracerebral Hemorrhage In 2020

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Delayed Minocycline Treatment Ameliorates Hydrocephalus Development and Choroid Plexus Inflammation in Spontaneously Hypertensive Rats

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