The more physical inactivity, the more agitation in dementia
Open accessAbstract
Epidemiological studies show a close relationship between physical activity and cognition. A causal relationship between physical activity and cognition has been observed in children, adolescents, older people without dementia, and in older people in a very early stage of dementia. Considering these positive effects, we argue that a decline in physical activity has a detrimental effect on cognition and behavior in patients with dementia. Merely living in a nursing home reduces the level of physical activity. The level of physical activity may even be reduced to a minimum when physical restraints are applied. The use of physical restraints coincides with stress, further aggravating the already existing neuropathology, which may increase stress and agitation even more. Exercise may reduce stress and agitation.
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Exercise reduces behavioral and psychological symptoms of dementia in patients with AD or dementia.
“Exercise has been documented to improve physical health and well-being (33), to reduce behavioral and psychological symptoms of dementia (BPSD) (34–36), and to enhance performance in the activities of daily living (ADL) (37, 38) in patients with AD or dementia.”
From The Multidisciplinary Approach to Alzheimer’s Disease and Dementia. A Narrative Review of Non-Pharmacological Treatment (2018) · cites this paper as [34]
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- Authors
- Scherder, E. J. A., Bogen, T., Eggermont, L. H. P., Hamers, J. P. H., & Swaab, D. F.
- Affiliations
- Vrije Universiteit Amsterdam (NL)
- Maastricht University (NL)
- Netherlands Institute for Neuroscience (NL)
- Corresponding author
- Scherder, Erik J.A.
- Venue
- International Psychogeriatrics
- Publisher
- Elsevier BV
- Published
- 2010-12
- Volume
- 22
- Issue
- 8
- Pages
- 1203-1208
- ISSN
- 1041-6102 (ISSN-L)
- OpenAlex
- W2099924709
- Cited by
- 121
- References
- 70
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 12 · 2023: 7 · 2022: 11 · 2021: 3 · 2020: 4 · 2019: 2 · 2018: 13 · 2017: 13 · 2016: 8 · 2015: 13 · 2014: 8 · 2013: 9 · 2012: 4
- FWCI
- 0.77
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Psychogeriatrics (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- KNAW research portal (Royal Academy of Art and Sciences (KNAW)) (publishedVersion)
- VU Research Portal (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Research Publications (Maastricht University) (submittedVersion, cc-by-nc-nd)
- Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) (submittedVersion)
- KNAW Research Portal (The Royal Netherlands Academy of Arts and Sciences) (submittedVersion)
- Research Publications (Maastricht University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
- Keywords
- physical inactivity, dementia, agitation, physical activity, cognition, physical restraint, nursing homes, stress, neuropathology
- MeSH terms
- Adolescent, Aged, Aged, 80 and over, Aging, Animals, Child, Cognition, Dementia, Homes for the Aged, Humans, Motor Activity, Nursing Homes, Psychomotor Agitation, Restraint, Physical, Stress, Psychological, Executive Function
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