Gastropod Mucus: Interdisciplinary Perspectives on Biological Activities, Applications, and Strategic Priorities
Open accessAbstract
Terrestrial gastropod mucus exhibits multifunctional attributes, enabling diverse applications. This comprehensive review integrates insights across biomedicine, biotechnology, and intellectual property to elucidate the bioactivities, physicochemical properties, and ecological roles of snail and slug mucus. Following an overview of mucus functional roles in gastropods, promising applications are highlighted in wound healing, antimicrobials, biomaterials, and cosmetics, alongside key challenges. An analysis of global patent trends reveals surging innovation efforts to leverage gastropod mucus. Strategic priorities include bioprospecting natural diversity, optimizing stabilization systems, recombinant biosynthesis, and fostering collaboration to translate promising potentials sustainably into impactful technologies. Ultimately, harnessing the remarkable multifunctionality of gastropod mucus holds immense opportunities for transformative innovations in biomedicine, biotechnology, and beyond.
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Snail mucus of different snail species is proposed for the treatment of chronic lesions, skin conditions, post-surgical infections, stomach ulcers, etc.
“Snail mucus of different snail species is proposed for the treatment of chronic lesions, skin conditions, post-surgical infections, stomach ulcers, etc. [62,65,66].”
From Chemical Variability and Biological Potential of Cornu aspersum Mucus as a Source for the Development of New Cosmetic and Pharmaceutical Products (2025) · cites this paper as [66]
The Wound Healing and Tissue Repair section describes potential uses for chronic wounds and infected skin wounds, while Cosmetic and Skincare Applications discusses inflammatory skin conditions. Other Therapeutic Applications reports antiulcer effects. The copy does not specifically propose snail mucus for post-surgical infections, so that part of the attributed claim is unsupported. (LLM, conf=0.87)
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Advancing Discovery of Snail Mucins Function and Application
McDermott, M., Cerullo, A. R., Parziale, J., Achrak, E., Sultana, S., Ferd, J., Samad, S., Deng, W., Braunschweig, A. B., & Holford, M. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.734023 · Cited by 77 · see citing works
Design of Liposomes Carrying HelixComplex Snail Mucus: Preliminary Studies
Alogna, A., Gentili, V., Trapella, C., Hallan, S. S., Sguizzato, M., Strazzabosco, G., Fernández, M., Cortesi, R., Rizzo, R., & Bortolotti, D. (2021) · Molecules · doi:10.3390/molecules26164709 · Cited by 14 · see citing works
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Cited by
Sorted by citations
Hudz, N., Turkina, V., Alyokhina, T., Motyka, O., Chemerys, N., Rumynska, T., Lozynskyi, A., Jasicka-Misiak, I., & Kobylinska, L. (2025) · Molecules · doi:10.3390/molecules30214197 · Cited by 4 · see citing works
- Authors
- Liegertová, M., & Malý, J.
- Affiliations
- Jan Evangelista Purkyně University in Ústí nad Labem (CZ)
- Corresponding author
- Liegertová, Michaela
- Venue
- ACS Biomaterials Science & Engineering
- Publisher
- American Chemical Society (ACS)
- Published
- 2023-09-26
- Volume
- 9
- Issue
- 10
- Pages
- 5567-5579
- ISSN
- 2373-9878 (ISSN-L)
- PMC
- PMC10566510
- OpenAlex
- W4387036646
- Cited by
- 36
- References
- 2
- Citations by year
- 2026: 16 · 2025: 17 · 2024: 2 · 2023: 1
- FWCI
- 1.01
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- ACS Biomaterials Science & Engineering (publishedVersion, cc-by-sa)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- Czech Science Foundation (Grantova Agentura Ceske Republiky - GACR) (20-21421S)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Mollusks and Parasites Studies
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Keywords
- snail mucus, wound healing, antimicrobial agents, biomaterials, cosmetics, patent trends, bioprospecting, land snails
- MeSH terms
- Animals, Anti-Infective Agents, Biocompatible Materials, Cosmetics, Humans, Mucus, Wound Healing, Gastropoda
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