Functions, Therapeutic Applications, and Synthesis of Retinoids and Carotenoids

Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds

Miyaura, N., & Suzuki, A. (1995) · Chemical Reviews · doi:10.1021/cr00039a007 · Cited by 12,878 · see citing works

Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor

Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Trong, I. L., Teller, D. C., Okada, T., Stenkamp, R. E., et al. (2000) · Science · doi:10.1126/science.289.5480.739 · Cited by 5,637 · see citing works

The Effect of Vitamin E and Beta Carotene on the Incidence of Lung Cancer and Other Cancers in Male Smokers

(1994) · New England Journal of Medicine · doi:10.1056/nejm199404143301501 · Cited by 4,737 · see citing works

Metal‐Catalyzed Cross‐Coupling Reactions

(2004) · Wiley eBooks · doi:10.1002/9783527619535 · Cited by 4,270 · see citing works

The Heck Reaction as a Sharpening Stone of Palladium Catalysis

Beletskaya, I. P., & Cheprakov, A. V. (2000) · Chemical Reviews · doi:10.1021/cr9903048 · Cited by 3,924 · see citing works

Crystal structure of oxygen-evolving photosystem II at a resolution of 1.9 Å

Umena, Y., Kawakami, K., Shen, J., & Kamiya, N. (2011) · Nature · doi:10.1038/nature09913 · Cited by 3,920 · see citing works

The Palladium‐Catalyzed Cross‐Coupling Reactions of Organotin Reagents with Organic Electrophiles [New Synthetic Methods (58)]

STILLE, J. K. (1986) · Angewandte Chemie International Edition in English · doi:10.1002/anie.198605081 · Cited by 3,397 · see citing works

Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize

Seechurn, C. C. C. J., Kitching, M. O., Colacot, T. J., & Snieckus, V. A. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201107017 · Cited by 3,019 · see citing works

The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry

Chinchílla, R., & Nájera, C. (2007) · Chemical Reviews · doi:10.1021/cr050992x · Cited by 2,986 · see citing works

Recent advances in the cross-coupling reactions of organoboron derivatives with organic electrophiles, 1995–1998

Suzuki, A. (1999) · Journal of Organometallic Chemistry · doi:10.1016/s0022-328x(98)01055-9 · Cited by 2,927 · see citing works

Crystal structure of an integral membrane light-harvesting complex from photosynthetic bacteria

McDermott, G., Prince, S. M., Freer, A. A., Hawthornthwaite, A. M., Papiz, M. Z., Cogdell, R. J., & Isaacs, N. W. (1995) · Nature · doi:10.1038/374517a0 · Cited by 2,741 · see citing works

Palladium‐Catalyzed Cross‐Coupling Reactions in Total Synthesis

Nicolaou, K. C., Bulger, P. G., & Šarlah, D. (2005) · Angewandte Chemie International Edition · doi:10.1002/anie.200500368 · Cited by 2,712 · see citing works

Channelrhodopsin-2, a directly light-gated cation-selective membrane channel

Nagel, G., Szellas, T., Huhn, W., Kateriya, S., Adeishvili, N., Berthold, P. R., Ollig, D., Hegemann, P., & Bamberg, E. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1936192100 · Cited by 2,672 · see citing works

Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands

Martı́n, R., & Buchwald, S. L. (2008) · Accounts of Chemical Research · doi:10.1021/ar800036s · Cited by 2,651 · see citing works

The Wittig olefination reaction and modifications involving phosphoryl-stabilized carbanions. Stereochemistry, mechanism, and selected synthetic aspects

Maryanoff, B. E., & Reitz, A. B. (1989) · Chemical Reviews · doi:10.1021/cr00094a007 · Cited by 2,612 · see citing works

Dynamic Covalent Chemistry

Rowan, S. J., Cantrill, S., Cousins, G. R. L., Sanders, J. K. M., & Stoddart, J. F. (2002) · Angewandte Chemie International Edition · doi:10.1002/1521-3773(20020315)41:6 · Cited by 2,599 · see citing works

Reconciling the chemistry and biology of reactive oxygen species

Winterbourn, C. C. (2008) · Nature Chemical Biology · doi:10.1038/nchembio.85 · Cited by 2,504 · see citing works

Neocortical excitation/inhibition balance in information processing and social dysfunction

Yizhar, O., Fenno, L. E., Prigge, M., Schneider, F., Davidson, T. J., O’Shea, D. J., Sohal, V. S., Goshen, I., Finkelstein, J., Paz, J. T., et al. (2011) · Nature · doi:10.1038/nature10360 · Cited by 2,454 · see citing works

Plant sesquiterpenes induce hyphal branching in arbuscular mycorrhizal fungi

Akiyama, K., Matsuzaki, K.-I., & Hayashi, H. (2005) · Nature · doi:10.1038/nature03608 · Cited by 2,429 · see citing works

Strigolactone inhibition of shoot branching

Gomez-Roldan, V., Fermas, S., Brewer, P. B., Puech-Pagès, V., Dun, E. A., Pillot, J.-P., Letisse, F., Matusova, R., Danoun, S., Portais, J.-C., et al. (2008) · Nature · doi:10.1038/nature07271 · Cited by 2,281 · see citing works

Mortality in Randomized Trials of Antioxidant Supplements for Primary and Secondary Prevention: Systematic Review and Meta-analysis

Bjelakovic, G., Nikolova, D., Gluud, L. L., Simonetti, R. G., & Gluud, C. (2007) · JAMA · doi:10.1001/jama.297.8.842 · Cited by 2,275 · see citing works

Engineering the Provitamin A (β-Carotene) Biosynthetic Pathway into (Carotenoid-Free) Rice Endosperm

Ye, X., Al‐Babili, S., Klöti, A., Zhang, J., Lucca, P., Beyer, P., & Potrykus, I. (2000) · Science · doi:10.1126/science.287.5451.303 · Cited by 2,270 · see citing works

ABSCISIC ACID BIOSYNTHESIS AND CATABOLISM

Nambara, E., & Marion‐Poll, A. (2005) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.56.032604.144046 · Cited by 2,246 · see citing works

Lycopene as the most efficient biological carotenoid singlet oxygen quencher

Mascio, P. D., Kaiser, S., & Sies, H. (1989) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(89)90467-0 · Cited by 2,238 · see citing works

Rhodopsin-like Protein from the Purple Membrane of Halobacterium halobium

Oesterhelt, D., & Stoeckenius, W. (1971) · Nature New Biology · doi:10.1038/newbio233149a0 · Cited by 2,152 · see citing works

Physical Mechanisms of Generation and Deactivation of Singlet Oxygen

Schweitzer, C., & Schmidt, R. (2003) · Chemical Reviews · doi:10.1021/cr010371d · Cited by 2,123 · see citing works

Inhibition of shoot branching by new terpenoid plant hormones

Umehara, M., Hanada, A., Yoshida, S., Akiyama, K., Arite, T., Takeda-Kamiya, N., Magome, H., Kamiya, Y., Shirasu, K., Yoneyama, K., et al. (2008) · Nature · doi:10.1038/nature07272 · Cited by 2,105 · see citing works

Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes

Yang, Q., Graham, T. E., Mody, N., Preitner, F., Peroni, O. D., Zabolotny, J. M., Kotani, K., Quadro, L., & Kahn, B. B. (2005) · Nature · doi:10.1038/nature03711 · Cited by 2,086 · see citing works

Solar Fuels via Artificial Photosynthesis

Gust, D., Moore, T. A., & Moore, A. L. (2009) · Accounts of Chemical Research · doi:10.1021/ar900209b · Cited by 2,065 · see citing works

Cross‐Coupling Reactions Of Organoboranes: An Easy Way To Construct CC Bonds (Nobel Lecture)

Suzuki, A. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201101379 · Cited by 2,054 · see citing works

Ruthenium-Based Heterocyclic Carbene-Coordinated Olefin Metathesis Catalysts

Vougioukalakis, G. C., & Grubbs, R. H. (2009) · Chemical Reviews · doi:10.1021/cr9002424 · Cited by 2,029 · see citing works

Carotenoids and human health

RAO, A., & RAO, L. (2007) · Pharmacological Research · doi:10.1016/j.phrs.2007.01.012 · Cited by 2,024 · see citing works

Retinoic acid embryopathy

Lammer, E. J., Chen, D. T., Hoar, R. M., Agnish, N. D., Benke, P. J., Braun, J. T., Curry, C. J., Fernhoff, P. M., Grix, A. W., Lott, I. T., et al. (1985) · New England Journal of Medicine · doi:10.1056/nejm198510033131401 · Cited by 1,942 · see citing works

Lessons from nature about solar light harvesting

Scholes, G. D., Fleming, G. R., Olaya-Castro, A., & van Grondelle, R. (2011) · Nature Chemistry · doi:10.1038/nchem.1145 · Cited by 1,915 · see citing works

Crystal structure of spinach major light-harvesting complex at 2.72 Å resolution

Liu, Z., Yan, H., Wang, K., Kuang, T., Zhang, J., Gui, L.-L., An, X., & Chang, W. (2004) · Nature · doi:10.1038/nature02373 · Cited by 1,693 · see citing works

TISSUE CHANGES FOLLOWING DEPRIVATION OF FAT-SOLUBLE A VITAMIN

Wolbach, S., & Howe, P. R. (1925) · Journal of Experimental Medicine · doi:10.1084/jem.42.6.753 · Cited by 1,674 · see citing works

Handbook of Metathesis

(2003) · Wiley eBooks · doi:10.1002/9783527619481 · Cited by 1,672 · see citing works

Mycorrhizal Symbiosis

(2002) · Elsevier eBooks · doi:10.1016/b978-0-12-652840-4.x5000-1 · Cited by 1,579 · see citing works

Recent advances in Sonogashira reactions

Chinchílla, R., & Nájera, C. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15071e · Cited by 1,543 · see citing works

A pigment-binding protein essential for regulation of photosynthetic light harvesting

Li, X., Björkman, O., Shih, C., Grossman, A. R., Rosenquist, M., Jansson, S., & Niyogi, K. (2000) · Nature · doi:10.1038/35000131 · Cited by 1,540 · see citing works

Bacterial Rhodopsin: Evidence for a New Type of Phototrophy in the Sea

Béjà, O., Aravind, L., Koonin, E. V., Suzuki, M. T., Hadd, A. G., Nguyen, L. P., Jovanovich, S. B., Gates, C. M., Feldman, R. A., Spudich, J. L., et al. (2000) · Science · doi:10.1126/science.289.5486.1902 · Cited by 1,532 · see citing works

Molecular signatures of G-protein-coupled receptors

Venkatakrishnan, A., Deupí, X., Lebon, G., Tate, C. G., Schertler, G. F. X., & Babu, M. M. (2013) · Nature · doi:10.1038/nature11896 · Cited by 1,502 · see citing works

Structure of bacteriorhodopsin at 1.55 Å resolution

Luecke, H., Schobert, B., Richter, H.-T., Cartailler, J., & Lanyi, J. Κ. (1999) · Journal of Molecular Biology · doi:10.1006/jmbi.1999.3027 · Cited by 1,452 · see citing works

Carotenoid actions and their relation to health and disease

Krinsky, N. I., & Johnson, E. J. (2005) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2005.10.001 · Cited by 1,422 · see citing works

Genome-wide analysis of estrogen receptor binding sites

Carroll, J. S., Meyer, C. A., Song, J. S., Li, W., Geistlinger, T., Eeckhoute, J., Brodsky, A. S., Keeton, E. K., Fertuck, K. C., Hall, G., et al. (2006) · Nature Genetics · doi:10.1038/ng1901 · Cited by 1,368 · see citing works

ABA perception and signalling

Raghavendra, A. S., Gonugunta, V. K., Christmann, A., & Grill, E. (2010) · Trends in Plant Science · doi:10.1016/j.tplants.2010.04.006 · Cited by 1,311 · see citing works

Selective carbon-carbon bond formation by cross-coupling of Grignard reagents with organic halides. Catalysis by nickel-phosphine complexes

Tamao, K., Sumitani, K., & Kumada, M. (1972) · Journal of the American Chemical Society · doi:10.1021/ja00767a075 · Cited by 1,292 · see citing works

Risk Factors for Lung Cancer and for Intervention Effects in CARET, the Beta-Carotene and Retinol Efficacy Trial

Omenn, G. S., Goodman, G. E., Thornquist, M. D., Balmes, J., Cullen, M. R., Glass, A., Keogh, J. P., Meyskens, F. L., Valanis, B., Williams, J. H., et al. (1996) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/88.21.1550 · Cited by 1,255 · see citing works

Principles for modulation of the nuclear receptor superfamily

Gronemeyer, H., Gustafsson, J.-Å., & Laudet, V. (2004) · Nature Reviews Drug Discovery · doi:10.1038/nrd1551 · Cited by 1,228 · see citing works

High-performance genetically targetable optical neural silencing by light-driven proton pumps

Chow, B. Y., Han, X., Dobry, A. S., Qian, X., Chuong, A. S., Li, M., Henninger, M. A., Belfort, G. M., Lin, Y., Monahan, P. E., et al. (2010) · Nature · doi:10.1038/nature08652 · Cited by 1,188 · see citing works

Metathesis Reactions in Total Synthesis

Nicolaou, K. C., Bulger, P. G., & Šarlah, D. (2005) · Angewandte Chemie International Edition · doi:10.1002/anie.200500369 · Cited by 1,185 · see citing works

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

Bourguet, W., Ruff, M., Chambon, P., Gronemeyer, H., & Moras, D. (1995) · Nature · doi:10.1038/375377a0 · Cited by 1,177 · see citing works

Channelrhodopsin-1: A Light-Gated Proton Channel in Green Algae

Nagel, G., Ollig, D., Fuhrmann, M., Kateriya, S., Musti, A. M., Bamberg, E., & Hegemann, P. (2002) · Science · doi:10.1126/science.1072068 · Cited by 1,166 · see citing works

Recent Developments in Olefin Cross‐Metathesis

Connon, S. J., & Blechert, S. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200200556 · Cited by 1,139 · see citing works

The genome of Tetranychus urticae reveals herbivorous pest adaptations

Grbić, M., Leeuwen, T. V., Clark, R. M., Rombauts, S., Rouzé, P., Grbić, V., Osborne, E. J., Dermauw, W., Ngoc, P. C. T., Ortego, F., et al. (2011) · Nature · doi:10.1038/nature10640 · Cited by 1,113 · see citing works

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

Renaud, J., Rochel, N., Ruff, M., Vivat, V., Chambon, P., Gronemeyer, H., & Moras, D. (1995) · Nature · doi:10.1038/378681a0 · Cited by 1,098 · see citing works

Retinoic Acid Synthesis and Signaling during Early Organogenesis

Duester, G. (2008) · Cell · doi:10.1016/j.cell.2008.09.002 · Cited by 1,098 · see citing works

The role of the xanthophyll cycle and of lutein in photoprotection of photosystem II

Jahns, P., & Holzwarth, A. R. (2011) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2011.04.012 · Cited by 1,086 · see citing works

Topics in current chemistry

Nixon, J. F. (1982) · Journal of Organometallic Chemistry · doi:10.1016/s0022-328x(00)85867-2 · Cited by 1,077 · see citing works

Crystal structure of opsin in its G-protein-interacting conformation

Scheerer, P., Park, J. H., Hildebrand, P. W., Kim, Y. J., Krauß, N., Choe, H.-W., Hofmann, K. P., & Ernst, O. P. (2008) · Nature · doi:10.1038/nature07330 · Cited by 1,059 · see citing works

Direct synthesis of Z-unsaturated esters. A useful modification of the horner-emmons olefination.

Still, W. C., & Gennari, C. (1983) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)85909-2 · Cited by 1,058 · see citing works

ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

Cramer, P. E., Cirrito, J. R., Wesson, D. W., Lee, C. Y. D., Karlo, J. C., Zinn, A. E., Casali, B. T., Restivo, J. L., Goebel, W. D., James, M. J., et al. (2012) · Science · doi:10.1126/science.1217697 · Cited by 1,050 · see citing works

Large rate accelerations in the stille reaction with tri-2-furylphosphine and triphenylarsine as palladium ligands: mechanistic and synthetic implications

Farina, V., & Krishnan, B. S. (1991) · Journal of the American Chemical Society · doi:10.1021/ja00025a025 · Cited by 1,041 · see citing works

Cis−Trans Isomerization of Organic Molecules and Biomolecules: Implications and Applications

Dugave, C., & Demange, L. (2003) · Chemical Reviews · doi:10.1021/cr0104375 · Cited by 1,033 · see citing works

The remarkable metal-catalysed olefin metathesis reaction

Hoveyda, A. H., & Zhugralin, A. R. (2007) · Nature · doi:10.1038/nature06351 · Cited by 1,009 · see citing works

The Retinoids-Biology, Chemistry and Medicine

Wolf, G. (1994) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/60.5.796a · Cited by 1,005 · see citing works

International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors

Michalik, L., Auwerx, J. H., Berger, J. P., Chatterjee, K., Glass, C. K., Gonzalez, F. J., Grimaldi, P. A., Kadowaki, T., Lazar, M. A., O’Rahilly, S., et al. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.4.5 · Cited by 997 · see citing works

Ruthenium-Based Olefin Metathesis Catalysts Bearing N-Heterocyclic Carbene Ligands

Samojłowicz, C., Bieniek, M., & Grela, K. (2009) · Chemical Reviews · doi:10.1021/cr800524f · Cited by 995 · see citing works

Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration

Seddon, J. M. (1994) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1994.03520180037032 · Cited by 993 · see citing works

A canonical structure for the ligand-binding domain of nuclear receptors

Wurtz, J., Bourguet, W., Renaud, J., Vivat, V., Chambon, P., Moras, D., & Gronemeyer, H. (1996) · Nature Structural Biology · doi:10.1038/nsb0196-87 · Cited by 986 · see citing works

The Mechanisms of the Stille Reaction

Espinet, P., & Echavarren, A. M. (2004) · Angewandte Chemie International Edition · doi:10.1002/anie.200300638 · Cited by 960 · see citing works

Recent advances and emerging trends in plant hormone signalling

Santner, A., & Estelle, M. (2009) · Nature · doi:10.1038/nature08122 · Cited by 960 · see citing works

Conical intersection dynamics of the primary photoisomerization event in vision

Polli, D., Altoè, P., Weingart, O., Spillane, K. M., Manzoni, C., Brida, D., Tomasello, G., Orlandi, G., Kukura, P., Mathies, R. A., et al. (2010) · Nature · doi:10.1038/nature09346 · Cited by 948 · see citing works

Organotrifluoroborates: Protected Boronic Acids That Expand the Versatility of the Suzuki Coupling Reaction

Molander, G. A., & Ellis, N. M. (2007) · Accounts of Chemical Research · doi:10.1021/ar050199q · Cited by 934 · see citing works

The Path from β-Carotene to Carlactone, a Strigolactone-Like Plant Hormone

Alder, A., Jamil, M., Marzorati, M., Bruno, M., Vermathen, M., Bigler, P., Ghisla, S., Bouwmeester, H. J., Beyer, P., & Al‐Babili, S. (2012) · Science · doi:10.1126/science.1218094 · Cited by 930 · see citing works

Identification of a mechanism of photoprotective energy dissipation in higher plants

Ruban, A. V., Berera, R., Ilioaia, C., van Stokkum, I. H. M., Kennis, J. T. M., Pascal, A. A., van Amerongen, H., Robert, B., Horton, P., & van Grondelle, R. (2007) · Nature · doi:10.1038/nature06262 · Cited by 920 · see citing works

Specific Oxidative Cleavage of Carotenoids by VP14 of Maize

Schwartz, S. H., Tan, B. C., Gage, D. A., Zeevaart, J. A. D., & McCarty, D. R. (1997) · Science · doi:10.1126/science.276.5320.1872 · Cited by 909 · see citing works

Crystal structure of the ligand-free G-protein-coupled receptor opsin

Park, J. H., Scheerer, P., Hofmann, K. P., Choe, H., & Ernst, O. P. (2008) · Nature · doi:10.1038/nature07063 · Cited by 903 · see citing works

Ultrafast Dynamics of Carotenoid Excited States−From Solution to Natural and Artificial Systems

Polı́vka, T., & Sundström, V. (2004) · Chemical Reviews · doi:10.1021/cr020674n · Cited by 897 · see citing works

Supramolecular organization of thylakoid membrane proteins in green plants

Dekker, J. P., & Boekema, E. J. (2004) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2004.09.009 · Cited by 891 · see citing works

A Membrane Receptor for Retinol Binding Protein Mediates Cellular Uptake of Vitamin A

Kawaguchi, R., Yu, J., Honda, J., Hu, J., Whitelegge, J., Ping, P., Wiita, P., Bok, D., & Sun, H. (2007) · Science · doi:10.1126/science.1136244 · Cited by 836 · see citing works

Recent Advances in Chemoprevention of Cancer

Hong, W. K., & Sporn, M. B. (1997) · Science · doi:10.1126/science.278.5340.1073 · Cited by 826 · see citing works

The Molecular Basis of Visual Excitation

WALD, G. (1968) · Nature · doi:10.1038/219800a0 · Cited by 824 · see citing works

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

Chandra, V., Huang, P., Hamuro, Y., Raghuram, S., Wang, Y., Burris, T. P., & Rastinejad, F. (2008) · Nature · doi:10.1038/nature07413 · Cited by 808 · see citing works

Mechanisms of photoprotection and nonphotochemical quenching in pea light‐harvesting complex at 2.5 Å resolution

Standfuss, J., van Scheltinga, A. C. T., Lamborghini, M., & Kühlbrandt, W. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600585 · Cited by 793 · see citing works

Carotenoid Cation Formation and the Regulation of Photosynthetic Light Harvesting

Holt, N. E., Zigmantas, D., Valkūnas, L., Li, X., Niyogi, K., & Fleming, G. R. (2005) · Science · doi:10.1126/science.1105833 · Cited by 792 · see citing works

Role of retinoids in differentiation and carcinogenesis.

Sporn, M. B., & Roberts, A. B. (1983) · PubMed · Cited by 786 · see citing works

The promise of retinoids to fight against cancer

Altucci, L., & Gronemeyer, H. (2001) · Nature Reviews Cancer · doi:10.1038/35106036 · Cited by 773 · see citing works

G Protein–Coupled Receptor Rhodopsin

Palczewski, K. (2006) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.75.103004.142743 · Cited by 764 · see citing works

Silicon-based cross-coupling reaction: an environmentally benign version

Nakao, Y., & Hiyama, T. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15122c · Cited by 764 · see citing works

Magical Power of Transition Metals: Past, Present, and Future (Nobel Lecture)

Negishi, E. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201101380 · Cited by 761 · see citing works

An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation.

Wilson, J. G., Roth, C., & Warkany, J. (1953) · American Journal of Anatomy · doi:10.1002/aja.1000920202 · Cited by 758 · see citing works

The photoprotective molecular switch in the photosystem II antenna

Ruban, A. V., Johnson, M. P., & Duffy, C. D. P. (2012) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2011.04.007 · Cited by 750 · see citing works

Simple and selective method for aldehydes (RCHO) .fwdarw. (E)-haloalkenes (RCH:CHX) conversion by means of a haloform-chromous chloride system

Takai, K., Nitta, K., & UTIMOTO, K. (1986) · Journal of the American Chemical Society · doi:10.1021/ja00283a046 · Cited by 749 · see citing works

Docosahexaenoic Acid, a Ligand for the Retinoid X Receptor in Mouse Brain

de Urquiza, A. M., Liu, S., Sjöberg, M., Zetterström, R. H., Griffiths, W. J., Sjövall, J., & Perlmann, T. (2000) · Science · doi:10.1126/science.290.5499.2140 · Cited by 745 · see citing works

Carotenoid oxidation products are stress signals that mediate gene responses to singlet oxygen in plants

Ramel, F., Birtić, S., Giniès, C., Soubigou‐Taconnat, L., Triantaphylidès, C., & Havaux, M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1115982109 · Cited by 728 · see citing works

An ancient light-harvesting protein is critical for the regulation of algal photosynthesis

Peers, G., Truong, T. B., Ostendorf, E., Busch, A., Elrad, D., Grossman, A. R., Hippler, M., & Niyogi, K. (2009) · Nature · doi:10.1038/nature08587 · Cited by 715 · see citing works

Zur Reaktionsweise des Pentaphenyl‐phosphors und einiger Derivate

Wittig, G., & Geissler, G. (1953) · Justus Liebig s Annalen der Chemie · doi:10.1002/jlac.19535800107 · Cited by 714 · see citing works

A Stereoselective Synthesis oftrans-1,2-Disubstituted Alkenes Based on the Condensation of Aldehydes with Metallated 1-Phenyl-1H-tetrazol-5-yl Sulfones

Blakemore, P. R., Cole, W. J., Kocieński, P., & Morley, A. (1998) · Synlett · doi:10.1055/s-1998-1570 · Cited by 711 · see citing works

The "Retinoic Acid Syndrome" in Acute Promyelocytic Leukemia

Frankel, S. R., Eardley, A., Lauwers, G. Y., Weiss, M. A., & Warrell, R. P. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-117-4-292 · Cited by 701 · see citing works

Quantum control of energy flow in light harvesting

Herek, J. L., Wohlleben, W., Cogdell, R. J., Zeidler, D., & Motzkus, M. (2002) · Nature · doi:10.1038/417533a · Cited by 697 · see citing works

Antioxidants in Photosynthesis and Human Nutrition

Demmig-Adams, B., & Adams, W. W. (2002) · Science · doi:10.1126/science.1078002 · Cited by 681 · see citing works

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Schenk, T., Chen, W. C., Göllner, S., Howell, L., Jin, L., Hebestreit, K., Klein, H.-U., Popescu, A. C., Burnett, A., Mills, K., et al. (2012) · Nature Medicine · doi:10.1038/nm.2661 · Cited by 672 · see citing works

Retinylidene Proteins: Structures and Functions from Archaea to Humans

Spudich, J. L., Yang, C., Jung, K., & Spudich, E. N. (2000) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.16.1.365 · Cited by 668 · see citing works

Crystal structure of metarhodopsin II

Choe, H.-W., Kim, Y. J., Park, J. H., Morizumi, T., Pai, E. F., Krauß, N., Hofmann, K. P., Scheerer, P., & Ernst, O. P. (2011) · Nature · doi:10.1038/nature09789 · Cited by 663 · see citing works

Functional role of internal water molecules in rhodopsin revealed by x-ray crystallography

Okada, T., Fujiyoshi, Y., Silow, M., Navarro, J., Landau, E. M., & Shichida, Y. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.082666399 · Cited by 662 · see citing works

Carotenoids: Handbook

(2004) · doi:10.1007/978-3-0348-7836-4 · Cited by 652 · see citing works

Structural Observation of the Primary Isomerization in Vision with Femtosecond-Stimulated Raman

Kukura, P., McCamant, D. W., Yoon, S., Wandschneider, D. B., & Mathies, R. A. (2005) · Science · doi:10.1126/science.1118379 · Cited by 648 · see citing works

Lateral Transfer of Genes from Fungi Underlies Carotenoid Production in Aphids

Moran, N. A., & Jarvik, T. (2010) · Science · doi:10.1126/science.1187113 · Cited by 648 · see citing works

The modified Julia olefination: alkene synthesis via the condensation of metallated heteroarylalkylsulfones with carbonyl compounds

Blakemore, P. R. (2002) · Journal of the Chemical Society Perkin Transactions 1 · doi:10.1039/b208078h · Cited by 647 · see citing works

Carotenoid Modulation of Immune Function and Sexual Attractiveness in Zebra Finches

Blount, J. D., Metcalfe, N. B., Birkhead, T. R., & Surai, P. F. (2003) · Science · doi:10.1126/science.1082142 · Cited by 642 · see citing works

Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer

Liby, K. T., Yore, M. M., & Sporn, M. B. (2007) · Nature Reviews Cancer · doi:10.1038/nrc2129 · Cited by 637 · see citing works

The Mizoroki–Heck Reaction

(2009) · Wiley eBooks · doi:10.1002/9780470716076 · Cited by 634 · see citing works

The Genetic Basis of Singlet OxygenInduced Stress Responses of Arabidopsis thaliana

Wagner, D., Przybyla, D., den Camp, R. O., Kim, C., Landgraf, F., Lee, K. P., Würsch, M., Laloi, C., Nater, M., Hideg, É., et al. (2004) · Science · doi:10.1126/science.1103178 · Cited by 630 · see citing works

Syntheses a l'aide de sulfones v(+)- methode de synthese generale de doubles liaisons.

JULIA, M., & Paris, J. (1973) · Tetrahedron Letters · doi:10.1016/s0040-4039(01)87348-2 · Cited by 613 · see citing works

Carotenoids and Their Isomers: Color Pigments in Fruits and Vegetables

Khoo, H. E., Prasad, K. N., Kong, K. W., Jiang, Y., & Ismail, A. (2011) · Molecules · doi:10.3390/molecules16021710 · Cited by 611 · see citing works

Biomarker evidence for green and purple sulphur bacteria in a stratified Palaeoproterozoic sea

Brocks, J. J., Love, G. D., Summons, R. E., Knoll, A. H., Logan, G. A., & Bowden, S. A. (2005) · Nature · doi:10.1038/nature04068 · Cited by 607 · see citing works

Molecular basis of photoprotection and control of photosynthetic light-harvesting

Pascal, A. A., Liu, Z., Broess, K., van Oort, B., van Amerongen, H., Wang, C., Horton, P., Robert, B., Chang, W., & Ruban, A. V. (2005) · Nature · doi:10.1038/nature03795 · Cited by 606 · see citing works

Vitamin A in Health and Disease

Blomhoff, R. (1994) · CRC Press eBooks · doi:10.1201/9781482277562 · Cited by 597 · see citing works

FUNCTION OF RETINOID NUCLEAR RECEPTORS: Lessons from Genetic and Pharmacological Dissections of the Retinoic Acid Signaling Pathway During Mouse Embryogenesis

Mark, M. P., Ghyselinck, N. B., & Chambon, P. (2005) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.46.120604.141156 · Cited by 596 · see citing works

Retinoids, Retinoic Acid Receptors, and Cancer

Tang, X.-H., & Gudas, L. J. (2011) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-011110-130303 · Cited by 596 · see citing works

Halorhodopsin is a light-driven chloride pump.

Schobert, B., & Lanyi, J. Κ. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34020-1 · Cited by 585 · see citing works

Proton Transfer Pathways in Bacteriorhodopsin at 2.3 Angstrom Resolution

Luecke, H., Richter, H.-T., & Lanyi, J. Κ. (1998) · Science · doi:10.1126/science.280.5371.1934 · Cited by 585 · see citing works

Carotenoids and their cleavage products: Biosynthesis and functions

Walter, M. H., & Strack, D. (2011) · Natural Product Reports · doi:10.1039/c0np00036a · Cited by 580 · see citing works

Palladium-Catalyzed Cross-Coupling Reactions of Organosilanols and Their Salts: Practical Alternatives to Boron- and Tin-Based Methods

Denmark, S. E., & Regens, C. S. (2008) · Accounts of Chemical Research · doi:10.1021/ar800037p · Cited by 571 · see citing works

Bacteriorhodopsin

Lanyi, J. Κ. (2004) · Annual Review of Physiology · doi:10.1146/annurev.physiol.66.032102.150049 · Cited by 570 · see citing works

The Vinylogous Aldol Reaction: A Valuable, Yet Understated Carbon−Carbon Bond-Forming Maneuver

Casiraghi, G., Zanardi, F., Appendino, G., & Rassu, G. (2000) · Chemical Reviews · doi:10.1021/cr990247i · Cited by 567 · see citing works

Structural determinants of nuclear receptor assembly on DNA direct repeats

Rastinejad, F., Perlmann, T., Evans, R. M., & Sigler, P. B. (1995) · Nature · doi:10.1038/375203a0 · Cited by 563 · see citing works

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors

Xu, H. E., Lambert, M. H., Montana, V. G., Plunket, K. D., Moore, L. B., Collins, J. L., Oplinger, J. A., Kliewer, S. A., Gampe, R. T., McKee, D. D., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.241410198 · Cited by 541 · see citing works

Structure of the Light-Driven Chloride Pump Halorhodopsin at 1.8 Å Resolution

Kolbe, M., Besir, H., Essen, L., & Oesterhelt, D. (2000) · Science · doi:10.1126/science.288.5470.1390 · Cited by 540 · see citing works

Two rhodopsins mediate phototaxis to low- and high-intensity light in Chlamydomonas reinhardtii

Sineshchekov, O. A., Jung, K.-H., & Spudich, J. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.122243399 · Cited by 539 · see citing works

Recent Advances in Efficient and Selective Synthesis of Di-, Tri-, and Tetrasubstituted Alkenes via Pd-Catalyzed Alkenylation−Carbonyl Olefination Synergy

Negishi, E., Huang, Z., Wang, G., Mohan, S., Wang, C., & Hattori, H. (2008) · Accounts of Chemical Research · doi:10.1021/ar800038e · Cited by 537 · see citing works

Bicycle-pedal model for the first step in the vision process

Warshel, A. (1976) · Nature · doi:10.1038/260679a0 · Cited by 533 · see citing works

Non-conventional methodologies for transition-metal catalysed carbon–carbon coupling: a critical overview. Part 2: The Suzuki reaction

Alonso, F., Beletskaya, I. P., & Yus, M. (2007) · Tetrahedron · doi:10.1016/j.tet.2007.12.036 · Cited by 532 · see citing works

Structural Overview of the Nuclear Receptor Superfamily: Insights into Physiology and Therapeutics

Huang, P., Chandra, V., & Rastinejad, F. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135917 · Cited by 530 · see citing works

Crystal structure of the channelrhodopsin light-gated cation channel

KATO, H. E., Zhang, F., Yizhar, O., Ramakrishnan, C., Nishizawa, T., Hirata, K., Ito, J., Aita, Y., Tsukazaki, T., Hayashi, S., et al. (2012) · Nature · doi:10.1038/nature10870 · Cited by 528 · see citing works

Architecture of a Charge-Transfer State Regulating Light Harvesting in a Plant Antenna Protein

Ahn, T. K., Avenson, T. J., Ballottari, M., Cheng, Y., Niyogi, K., Bassi, R., & Fleming, G. R. (2008) · Science · doi:10.1126/science.1154800 · Cited by 525 · see citing works

Light-driven production of ATP catalysed by F0F1-ATP synthase in an artificial photosynthetic membrane

Steinberg-Yfrach, G., Rigaud, J., Durantini, E. N., Moore, A. L., Gust, D., & Moore, T. A. (1998) · Nature · doi:10.1038/33116 · Cited by 525 · see citing works

Carotenoids in nature: insights from plants and beyond

Cazzonelli, C. I. (2011) · Functional Plant Biology · doi:10.1071/fp11192 · Cited by 519 · see citing works

RAR and RXR modulation in cancer and metabolic disease

Altucci, L., Leibowitz, M. D., Ogilvie, K. M., de Lera, A. R., & Gronemeyer, H. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2397 · Cited by 517 · see citing works

The Microbial Opsin Family of Optogenetic Tools

Zhang, F., Vierock, J., Yizhar, O., Fenno, L. E., Tsunoda, S. P., Kianianmomeni, A., Prigge, M., Berndt, A., Cushman, J. C., Polle, J. E. W., et al. (2011) · Cell · doi:10.1016/j.cell.2011.12.004 · Cited by 512 · see citing works

International Union of Pharmacology. LXIII. Retinoid X receptors

Germain, P., Chambon, P., Eichele, G., Evans, R. M., Lazar, M. A., Leid, M., De Lera, A. R., Lotan, R., Mangelsdorf, D. J., & Gronemeyer, H. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.4.7 · Cited by 496 · see citing works

New method for the reductive coupling of carbonyls to olefins. Synthesis of .beta.-carotene

McMurry, J. E., & Fleming, M. P. (1974) · Journal of the American Chemical Society · doi:10.1021/ja00821a076 · Cited by 493 · see citing works

Palladium-Catalysed Reactions of Organotin Compounds

Mitchell, T. N. (1992) · Synthesis · doi:10.1055/s-1992-26230 · Cited by 491 · see citing works

A Cholesterol Biosynthesis Inhibitor Blocks <i>Staphylococcus aureus</i> Virulence

Liu, C.-I., Liu, G. Y., Song, Y., Yin, F., Hensler, M. E., Jeng, W.-Y., Nizet, V., Wang, A. H.-J., & Oldfield, E. (2008) · Science · doi:10.1126/science.1153018 · Cited by 490 · see citing works

A High-Light Sensitivity Optical Neural Silencer: Development and Application to Optogenetic Control of Non-Human Primate Cortex

Han, X., Chow, B. Y., Zhou, H., Klapoetke, N. C., Chuong, A. S., Rajimehr, R., Yang, A., Baratta, M. V., Winkle, J. A., Desimone, R., et al. (2011) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2011.00018 · Cited by 490 · see citing works

The structure of a plant photosystem I supercomplex at 3.4 Å resolution

Amunts, A., Drory, O., & Nelson, N. (2007) · Nature · doi:10.1038/nature05687 · Cited by 490 · see citing works

Crystal structure of squid rhodopsin

Murakami, M., & Kouyama, T. (2008) · Nature · doi:10.1038/nature06925 · Cited by 486 · see citing works

Bacteriorhodopsin as a Photochromic Retinal Protein for Optical Memories

Hampp, N. (2000) · Chemical Reviews · doi:10.1021/cr980072x · Cited by 486 · see citing works

Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications

Bourguet, W., Germain, P., & Gronemeyer, H. (2000) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(00)01548-0 · Cited by 483 · see citing works

The structural basis of agonist-induced activation in constitutively active rhodopsin

Standfuss, J., Edwards, P. C., D’Antona, A. M., Fransen, M. P., Xie, G., Oprian, D. D., & Schertler, G. F. X. (2011) · Nature · doi:10.1038/nature09795 · Cited by 477 · see citing works

Isolation and one-step preparation of A2E and <i>iso</i> -A2E, fluorophores from human retinal pigment epithelium

Parish, C. A., Hashimoto, M., Nakanishi, K., Dillon, J., & Sparrow, J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.14609 · Cited by 474 · see citing works

Chemical Quenching of Singlet Oxygen by Carotenoids in Plants

Ramel, F., Birtić, S., Cuiné, S., Triantaphylidès, C., Ravanat, J., & Havaux, M. (2012) · PLANT PHYSIOLOGY · doi:10.1104/pp.111.182394 · Cited by 471 · see citing works

Structural Basis of Light Harvesting by Carotenoids: Peridinin-Chlorophyll-Protein from Amphidinium carterae

Hofmann, E., Wrench, P. M., Sharples, F. P., Hiller, R. G., Welte, W., & Diederichs, K. (1996) · Science · doi:10.1126/science.272.5269.1788 · Cited by 469 · see citing works

Synthesis and Metal-Catalyzed Reactions of gem-Dihalovinyl Systems

Chelucci, G. (2011) · Chemical Reviews · doi:10.1021/cr200165q · Cited by 465 · see citing works

Copper-Mediated Cross-Coupling of Organostannanes with Organic Iodides at or below Room Temperature

Allred, G. D., & Liebeskind, L. S. (1996) · Journal of the American Chemical Society · doi:10.1021/ja9541239 · Cited by 464 · see citing works

Attenuation of Colon Inflammation through Activators of the Retinoid X Receptor (Rxr)/Peroxisome Proliferator–Activated Receptor γ (Pparγ) Heterodimer

Desreumaux, P., Dubuquoy, L., Nutten, S., Peuchmaur, M. M., Englaro, W., Schoonjans, K., Dérijard, B., Desvergne, B., Wahli, W., Chambon, P., et al. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.193.7.827 · Cited by 458 · see citing works

Biosynthesis of a major lipofuscin fluorophore in mice and humans with <i>ABCR</i> -mediated retinal and macular degeneration

Mata, N. L., Weng, J., & Travis, G. H. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.130110497 · Cited by 456 · see citing works

Identification and Characterization of a Mammalian Enzyme Catalyzing the Asymmetric Oxidative Cleavage of Provitamin A

Kiefer, C., Hessel, S., Lampert, J. M., Vogt, K., Lederer, M. O., Breithaupt, D. E., & Lintig, J. V. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m011510200 · Cited by 453 · see citing works

Filling the Gap in Vitamin A Research

von Lintig, J., & Vogt, K. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.16.11915 · Cited by 449 · see citing works

Conversion of light energy to proton potential in liposomes by artificial photosynthetic reaction centres

Steinberg-Yfrach, G., Liddell, P. A., Hung, S.-C., Moore, A. L., Gust, D., & Moore, T. A. (1997) · Nature · doi:10.1038/385239a0 · Cited by 444 · see citing works

Molecular mechanism of vectorial proton translocation by bacteriorhodopsin

Subramaniam, S., & Henderson, R. A. (2000) · Nature · doi:10.1038/35020614 · Cited by 442 · see citing works

Crystal structure of a photoactivated deprotonated intermediate of rhodopsin

Salom, D., Lodowski, D. T., Stenkamp, R. E., Trong, I. L., Golczak, M., Jastrzebska, B., Harris, T., Ballesteros, J. A., & Palczewski, K. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608022103 · Cited by 442 · see citing works

Vitamin A in Reproduction and Development

Clagett-Dame, M., & Knutson, D. (2011) · Nutrients · doi:10.3390/nu3040385 · Cited by 439 · see citing works

Organotrifluoroborates and Monocoordinated Palladium Complexes as Catalysts—A Perfect Combination for Suzuki–Miyaura Coupling

Molander, G. A., & Canturk, B. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200904306 · Cited by 435 · see citing works

The Beta-Carotene and Retinol Efficacy Trial: Incidence of Lung Cancer and Cardiovascular Disease Mortality During 6-Year Follow-up After Stopping -Carotene and Retinol Supplements

Goodman, G. E., Thornquist, M. D., Balmes, J. R., Cullen, M. R., Meyskens, F. L., Omenn, G. S., VALANIS, B. G., & Williams, J. H. (2004) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djh320 · Cited by 430 · see citing works

Regulation and function of xanthophyll cycle-dependent photoprotection in algae

Goss, R., & Jakob, T. (2010) · Photosynthesis Research · doi:10.1007/s11120-010-9536-x · Cited by 429 · see citing works

Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia

Hu, J., Liu, Y.-F., Wu, C.-F., Xu, F., Shen, Z.-X., Zhu, Y., Li, J., Tang, W., Zhao, W.-L., Wu, W., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813280106 · Cited by 425 · see citing works

Retinoid-binding proteins: mediators of retinoid action

NOY, N. (2000) · Biochemical Journal · doi:10.1042/bj3480481 · Cited by 422 · see citing works

Carbon–carbon bonding made easy

Suzuki, A. (2005) · Chemical Communications · doi:10.1039/b507375h · Cited by 422 · see citing works

Retinoid-binding proteins: mediators of retinoid action

Noy, N. (2000) · Biochemical Journal · doi:10.1042/0264-6021:3480481 · Cited by 420 · see citing works

Ligand-Based Targeting of Apoptosis in Cancer: The Potential of Recombinant Human Apoptosis Ligand 2/Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (rhApo2L/TRAIL)

Ashkenazi, A., Holland, P. M., & Eckhardt, S. G. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.15.7198 · Cited by 420 · see citing works

Crystal Structure of a Heterodimeric Complex of RAR and RXR Ligand-Binding Domains

Bourguet, W., Vivat, V., Wurtz, J., Chambon, P., Gronemeyer, H., & Moras, D. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80424-4 · Cited by 405 · see citing works

Identification of lutein and zeaxanthin oxidation products in human and monkey retinas.

Khachik, F., Bernstein, P. S., & Garland, D. L. (1997) · PubMed · Cited by 404 · see citing works

International Union of Pharmacology. LX. Retinoic Acid Receptors

Germain, P., Chambon, P., Gregor Eichele, C., Evans, R. M., Lazar, M. A., Leid, M. E., de Lera, Á. R., Lotan, R., Mangelsdorf, D. J., & Gronemeyer, H. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.4.4 · Cited by 398 · see citing works

Immune Activation Rapidly Mirrored in a Secondary Sexual Trait

Faivre, B., Grégoire, A., Préault, M., Cézilly, F., & Sorci, G. (2003) · Science · doi:10.1126/science.1081802 · Cited by 396 · see citing works

Molecular basis of transmembrane signalling by sensory rhodopsin II–transducer complex

Gordeliy, V., Labahn, J., Moukhametzianov, R., Efremov, R. G., Granzin, J., Schlesinger, R., Büldt, G., Savopol, T., Scheidig, A. J., Klare, J. P., et al. (2002) · Nature · doi:10.1038/nature01109 · Cited by 395 · see citing works

Transmetalation in the Suzuki–Miyaura Coupling: The Fork in the Trail

Lennox, A. J. J., & Lloyd‐Jones, G. C. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201301737 · Cited by 394 · see citing works

Golden Rice is an effective source of vitamin A

Tang, G., Qin, J., Dolnikowski, G. G., Russell, R. M., & Grusak, M. A. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.27119 · Cited by 393 · see citing works

Terpene Biosynthesis: Modularity Rules

Oldfield, E., & Lin, F. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201103110 · Cited by 392 · see citing works

THE NECESSITY OF CERTAIN LIPINS IN THE DIET DURING GROWTH

McCollum, E. V., & Davis, M. (1913) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)88553-2 · Cited by 386 · see citing works

Overexpression of β-carotene hydroxylase enhances stress tolerance in Arabidopsis

Davison, P. A., Hunter, C. N., & Horton, P. (2002) · Nature · doi:10.1038/nature00861 · Cited by 385 · see citing works

Identification of the Retinoic Acid-inducible All-trans-retinoic Acid 4-Hydroxylase

White, J. A., Guo, Y.-D., Baetz, K., Beckett-Jones, B., Bonasoro, J., Hsu, K. E., Dilworth, F. J., Jones, G., & Petkovich, M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.47.29922 · Cited by 382 · see citing works

Retinoid X Receptor Heterodimers in the Metabolic Syndrome

Shulman, A. I., & Mangelsdorf, D. J. (2005) · New England Journal of Medicine · doi:10.1056/nejmra043590 · Cited by 380 · see citing works

Retinaldehyde represses adipogenesis and diet-induced obesity

Ziouzenkova, O., Orasanu, G., Sharlach, M., Akiyama, T. E., Berger, J. P., Viereck, J. C., Hamilton, J. A., Tang, G., Dolnikowski, G. G., Vogel, S., et al. (2007) · Nature Medicine · doi:10.1038/nm1587 · Cited by 380 · see citing works

Structure and Biosynthesis of Staphyloxanthin from Staphylococcus aureus

Pelz, A., Wieland, K.-P., Putzbach, K., Hentschel, P., Albert, K., & Götz, F. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m505070200 · Cited by 378 · see citing works

A G protein-coupled receptor at work: the rhodopsin model

Hofmann, K. P., Scheerer, P., Hildebrand, P. W., Choe, H.-W., Park, J. H., Heck, M., & Ernst, O. P. (2009) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2009.07.005 · Cited by 376 · see citing works

Retinoid pathway and cancer therapeutics

Bushue, N., & Wan, Y. Y. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.07.003 · Cited by 373 · see citing works

Coherent Control of Retinal Isomerization in Bacteriorhodopsin

Prokhorenko, V. I., Nagy, A. M., Waschuk, S. A., Brown, L. S., Birge, R. R., & Miller, R. J. D. (2006) · Science · doi:10.1126/science.1130747 · Cited by 371 · see citing works

Molecular Factors Controlling Photosynthetic Light Harvesting by Carotenoids

Polı́vka, T., & Frank, H. A. (2010) · Accounts of Chemical Research · doi:10.1021/ar100030m · Cited by 369 · see citing works

Sterically demanding trialkylphosphines for palladium-catalyzed cross coupling reactions—alternatives to PtBu3

Fleckenstein, C. A., & Plenio, H. (2009) · Chemical Society Reviews · doi:10.1039/b903646f · Cited by 365 · see citing works

Mechanisms involved in the intestinal absorption of dietary vitamin A and provitamin A carotenoids

Harrison, E. H. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.06.002 · Cited by 365 · see citing works

A stereoselective synthesis of (Z)-1-iodo-1-alkenes

Stork, G., & Zhao, K. (1989) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)99640-0 · Cited by 365 · see citing works

Function of retinoic acid receptors during embryonic development

Mark, M., Ghyselinck, N. B., & Chambon, P. (2009) · Nuclear Receptor Signaling · doi:10.1621/nrs.07002 · Cited by 363 · see citing works

Astaxanthin: A Potential Therapeutic Agent in Cardiovascular Disease

Fassett, R. G., & Coombes, J. S. (2011) · Marine Drugs · doi:10.3390/md9030447 · Cited by 349 · see citing works

Xanthorhodopsin: A Proton Pump with a Light-Harvesting Carotenoid Antenna

Balashov, S. P., Imasheva, E. S., Boichenko, V. A., Antón, J., Wang, J. M., & Lanyi, J. Κ. (2005) · Science · doi:10.1126/science.1118046 · Cited by 346 · see citing works

One Hundred Years of Vitamins—A Success Story of the Natural Sciences

Eggersdorfer, M. L., Laudert, D., Halbes‐Létinois, U., McClymont, T., Medlock, J., Netscher, T., & Bonrath, W. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201205886 · Cited by 346 · see citing works

Dietary intake of antioxidants and risk of age-related macular degeneration

van Leeuwen, R. (2005) · JAMA · doi:10.1001/jama.294.24.3101 · Cited by 345 · see citing works

Crystal structure of the human RXRα ligand‐binding domain bound to its natural ligand: 9‐cis retinoic acid

Egea, P. F., Mitschler, A., Rochel, N., Ruff, M., Chambon, P., & Moras, D. (2000) · The EMBO Journal · doi:10.1093/emboj/19.11.2592 · Cited by 343 · see citing works

Cultivation, Genetic, Ethnopharmacology, Phytochemistry and Pharmacology of Moringa oleifera Leaves: An Overview

Leone, A., Spada, A., Battezzati, A., Schiraldi, A., Aristil, J., & Bertoli, S. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160612791 · Cited by 807 · see citing works

Natural product and natural product derived drugs in clinical trials

Butler, M. S., Robertson, A. A. B., & Cooper, M. A. (2014) · Natural Product Reports · doi:10.1039/c4np00064a · Cited by 605 · see citing works

Bioactive Components in Moringa Oleifera Leaves Protect against Chronic Disease

Vergara-Jiménez, M. D. J., Almatrafi, M. M., & Fernández, M. L. (2017) · Antioxidants · doi:10.3390/antiox6040091 · Cited by 593 · see citing works

A new class of synthetic retinoid antibiotics effective against bacterial persisters

Kim, W., Zhu, W., Hendricks, G. L., Tyne, D. V., Steele, A. D., Keohane, C. E., Fricke, N., Conery, A. L., Shen, S., Pan, W., et al. (2018) · Nature · doi:10.1038/nature26157 · Cited by 412 · see citing works

An Overview of Carotenoids, Apocarotenoids, and Vitamin A in Agro‐Food, Nutrition, Health, and Disease

Meléndez‐Martínez, A. J. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201801045 · Cited by 263 · see citing works

Production of carotenoids by microalgae: achievements and challenges

Varela, J. C. S., Pereira, H., Vilà, M., & León, R. (2015) · Photosynthesis Research · doi:10.1007/s11120-015-0149-2 · Cited by 252 · see citing works

Skin Carotenoids in Public Health and Nutricosmetics: The Emerging Roles and Applications of the UV Radiation-Absorbing Colourless Carotenoids Phytoene and Phytofluene

Meléndez‐Martínez, A. J., Stinco, C. M., & Mapelli‐Brahm, P. (2019) · Nutrients · doi:10.3390/nu11051093 · Cited by 234 · see citing works

β-Carotene—properties and production methods

Bogacz-Radomska, L., & Harasym, J. (2018) · Food Quality and Safety · doi:10.1093/fqsafe/fyy004 · Cited by 216 · see citing works

Strategies to Combat Multidrug-Resistant and Persistent Infectious Diseases

Pacios, O., Blasco, L., Bleriot, I., Fernández-García, L., Bardanca, M. G., Ambroa, A., Bou, G., López, M. C., & Tomás, M. (2020) · Antibiotics · doi:10.3390/antibiotics9020065 · Cited by 189 · see citing works

Singlet Oxygen and Free Radical Reactions of Retinoids and Carotenoids—A Review

Edge, R., & Truscott, T. G. (2018) · Antioxidants · doi:10.3390/antiox7010005 · Cited by 182 · see citing works

Biogenic colourants in the textile industry – a promising and sustainable alternative to synthetic dyes

Fried, R., Oprea, I., Fleck, K., & Rudroff, F. (2021) · Green Chemistry · doi:10.1039/d1gc02968a · Cited by 174 · see citing works

The impact of fermentation processes on the production, retention and bioavailability of carotenoids: An overview

Mapelli‐Brahm, P., Barba, F. J., Remize, F., Garcia, C., Fessard, A., Khaneghah, A. M., Sant’Ana, A. S., Lorenzo, J. M., Montesano, D., & Meléndez‐Martínez, A. J. (2020) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2020.03.013 · Cited by 161 · see citing works

Mediterranean diet and inflammaging within the hormesis paradigm

Martucci, M., Ostan, R., Biondi, F., Bellavista, E., Fabbri, C., Bertarelli, C., Salvioli, S., Capri, M., Franceschi, C., & Santoro, A. (2017) · Nutrition Reviews · doi:10.1093/nutrit/nux013 · Cited by 160 · see citing works

Encapsulation of carotenoids in emulsion-based delivery systems: Enhancement of β-carotene water-dispersibility and chemical stability

Chen, J., Li, F., Li, Z., McClements, D. J., & Xiao, H. (2017) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2017.01.024 · Cited by 148 · see citing works

Reported Dietary Intake and Food Sources of Zinc, Selenium, and Vitamins A, E and C in the Spanish Population: Findings from the ANIBES Study

Olza, J., Bartrina, J. A., González‐Gross, M., Anta, R. M. O., Serra‐Majem, L., Varela‐Moreiras, G., & Gil, Á. (2017) · Nutrients · doi:10.3390/nu9070697 · Cited by 121 · see citing works

Effects of realistic doses of atrazine, metolachlor, and glyphosate on lipid peroxidation and diet-derived antioxidants in caged honey bees (Apis mellifera)

Helmer, S. H., Kerbaol, A., Aras, P., Jumarie, C., & Boily, M. H. (2014) · Environmental Science and Pollution Research · doi:10.1007/s11356-014-2879-7 · Cited by 119 · see citing works

Prospective Symbiosis of Green Chemistry and Energetic Materials

Kuchurov, I. V., Zharkov, M. N., Fershtat, L. L., Makhova, N. N., & Zlotin, S. G. (2017) · ChemSusChem · doi:10.1002/cssc.201701053 · Cited by 118 · see citing works

Stimulus-responsive light-harvesting complexes based on the pillararene-induced co-assembly of β-carotene and chlorophyll

Sun, Y., Guo, F. Z., Zuo, T., Hua, J., & Diao, G. (2016) · Nature Communications · doi:10.1038/ncomms12042 · Cited by 110 · see citing works

The Role of Vitamin A in Retinal Diseases

Sajovic, J., Meglič, A., Glavač, D., Markelj, Š., Hawlina, M., & Fakin, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031014 · Cited by 109 · see citing works

Biosynthesis of Carotenoids in Plants: Enzymes and Color

Rosas-Saavedra, C., & Stange, C. (2016) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-319-39126-7_2 · Cited by 108 · see citing works

Synthetic Multienzyme Complexes, Catalytic Nanomachineries for Cascade Biosynthesis In Vivo

Qu, J., Cao, S., Wei, Q., Zhang, H., Wang, R. Y., Kang, W., Ma, T., Zhang, L. N., Liu, T., Au, S. W., et al. (2019) · ACS Nano · doi:10.1021/acsnano.9b03631 · Cited by 98 · see citing works

Metabolic engineering of β-carotene biosynthesis in Yarrowia lipolytica

Zhang, X.-K., Wang, D., Chen, J., Liu, Z., Wei, L., & Hua, Q. (2020) · Biotechnology Letters · doi:10.1007/s10529-020-02844-x · Cited by 94 · see citing works

Regulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations

le Maire, A., Teyssier, C., Balaguer, P., Bourguet, W., & Germain, P. (2019) · Cells · doi:10.3390/cells8111392 · Cited by 88 · see citing works

Lycopene: Emerging Production Methods and Applications of a Valued Carotenoid

Ciriminna, R., Fidalgo, A. M., Meneguzzo, F., Ilharco, L. M., & Pagliaro, M. (2016) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.5b01516 · Cited by 82 · see citing works

Recent developments in the chemistry of ferrocenyl secondary natural product conjugates

Kowalski, K. (2018) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2018.04.008 · Cited by 81 · see citing works

Photoinduced C(sp3)−N Bond Cleavage Leading to the Stereoselective Syntheses of Alkenes

Yang, Z., Xu, N., Wang, C., & Uchiyama, M. (2019) · Chemistry - A European Journal · doi:10.1002/chem.201900886 · Cited by 81 · see citing works

Direct catalytic cross-coupling of alkenyllithium compounds

Hornillos, V., Giannerini, M., Vila, C., Fañanás‐Mastral, M., & Feringa, B. L. (2014) · Chemical Science · doi:10.1039/c4sc03117b · Cited by 79 · see citing works

Cellular and molecular determinants of all‐trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression

Centritto, F., Paroni, G., Bolis, M., Garattini, S. K., Kurosaki, M., Barzago, M. M., Zanetti, A., Fisher, J. N., Scott, M. F., Pattini, L., et al. (2015) · EMBO Molecular Medicine · doi:10.15252/emmm.201404670 · Cited by 77 · see citing works

An overview of β-carotene production: Current status and future prospects

Singh, R. V., & Sambyal, K. (2022) · Food Bioscience · doi:10.1016/j.fbio.2022.101717 · Cited by 76 · see citing works

Altered hepatic genes related to retinol metabolism and plasma retinol in patients with non-alcoholic fatty liver disease

Pettinelli, P., Arendt, B. M., Teterina, A. A., McGilvray, I. D., Comelli, E. M., Fung, S. K., Fischer, S. E., & Allard, J. P. (2018) · PLoS ONE · doi:10.1371/journal.pone.0205747 · Cited by 75 · see citing works

Alkenylation of unactivated alkyl bromides through visible light photocatalysis

Zhou, Q., Düsel, S. J. S., Lu, L., König, B., & Xiao, W. (2018) · Chemical Communications · doi:10.1039/c8cc08362b · Cited by 74 · see citing works

Role of Beta-Carotene in Lung Cancer Primary Chemoprevention: A Systematic Review with Meta-Analysis and Meta-Regression

Kordiak, J., Bielec, F., Jabłoński, S., & Pastuszak‐Lewandoska, D. (2022) · Nutrients · doi:10.3390/nu14071361 · Cited by 73 · see citing works

Environmental Pollutants and Oxidative Stress in Terrestrial and Aquatic Organisms: Examination of the Total Picture and Implications for Human Health

Anetor, G. O., Nwobi, N. L., Igharo, O. G., Sonuga, O. O., & Anetor, J. I. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.931386 · Cited by 81 · see citing works

Carotenoids modulate stress tolerance and immune responses in aquatic animals

Lim, K. C., Yusoff, F. M., Karim, M., & Ikhsan, N. F. M. (2022) · Reviews in Aquaculture · doi:10.1111/raq.12767 · Cited by 71 · see citing works

Vitamin A in health care: Suppression of growth and induction of differentiation in cancer cells by vitamin A and its derivatives and their mechanisms of action

Takahashi, N. K., Saito, D., Hasegawa, S., Yamasaki, M., & Imai, M. (2021) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2021.107942 · Cited by 70 · see citing works

Beta-carotene and its protective effect on gastric cancer

Chen, Q.-H., Wu, B., Pan, D., Sang, L.-X., & Chang, B. (2021) · World Journal of Clinical Cases · doi:10.12998/wjcc.v9.i23.6591 · Cited by 70 · see citing works

The colorful world of carotenoids: a profound insight on therapeutics and recent trends in nano delivery systems

Maghsoudi, S., Shahraki, B. T., Rabiee, N., Fatahi, Y., Bagherzadeh, M., Dinarvand, R., Ahmadi, S., Rabiee, M., Tahriri, M., Hamblin, M. R., et al. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1867958 · Cited by 68 · see citing works

Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase-3 activation, decreased Bcl-2 levels, increased p53 expression and PARP cleavage

Vizetto‐Duarte, C., Custódio, L. M. B., Gangadhar, K. N., Lago, J. H. G., Dias, C., de Matos, A. M., Neng, N. R., Nogueira, J. M. F., Barreira, L. A., Alberício, F., et al. (2016) · Phytomedicine · doi:10.1016/j.phymed.2016.02.008 · Cited by 66 · see citing works

Efficient production of retinol in Yarrowia lipolytica by increasing stability using antioxidant and detergent extraction

Park, H.-M., Lee, D., Kim, J.-E., Park, S., Park, J. H., Ha, C. W., Baek, M., Yoon, S.-H., Park, K. H., Lee, P., et al. (2022) · Metabolic Engineering · doi:10.1016/j.ymben.2022.06.001 · Cited by 61 · see citing works

Disease Prevention and Treatment Using β-Carotene: the Ultimate Provitamin A

Anand, R., Mohan, L., & Bharadvaja, N. (2022) · Revista Brasileira de Farmacognosia · doi:10.1007/s43450-022-00262-w · Cited by 61 · see citing works

Zeaxanthin and ocular health, from bench to bedside

Manikandan, R., Raman, T., Goutham, G., Arumugam, M., Manikandan, B., Rastrelli, L., Skalicka‐Woźniak, K., Habtemariam, S., Orhan, İ. E., Nabavi, S. F., et al. (2015) · Fitoterapia · doi:10.1016/j.fitote.2015.12.009 · Cited by 59 · see citing works

Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures

Silvaroli, J. A., Arne, J. M., Chełstowska, S., Kiser, P. D., Banerjee, S., & Golczak, M. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.714535 · Cited by 49 · see citing works

Moringa oleifera: Miracle Plant with a Plethora of Medicinal, Therapeutic, and Economic Importance

Prajapati, C., Ankola, M., Upadhyay, T. K., Sharangi, A. B., Alabdallah, N. M., Al‐Saeed, F. A., Muzammil, K., & Saeed, M. (2022) · Horticulturae · doi:10.3390/horticulturae8060492 · Cited by 52 · see citing works

Novel tetrazoloquinoline–rhodanine conjugates: Highly efficient synthesis and biological evaluation

Subhedar, D. D., Shaikh, M. H., Nawale, L., Yeware, A. M., Sarkar, D. M., Khan, F. A. K., Sangshetti, J. N., & Shingate, B. B. (2016) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2016.03.045 · Cited by 51 · see citing works

Vegetable phytochemicals: An update on extraction and analysis techniques

Sharma, M., & Kaushik, P. (2021) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2021.102149 · Cited by 51 · see citing works

Production of xylose enriched hydrolysate from bioenergy sorghum and its conversion to β-carotene using an engineered Saccharomyces cerevisiae

Cheng, M., Sun, L., Jin, Y., Dien, B. S., & Singh, V. (2020) · Bioresource Technology · doi:10.1016/j.biortech.2020.123275 · Cited by 50 · see citing works

Molecular components affecting ocular carotenoid and retinoid homeostasis

von Lintig, J., Moon, J., & Babino, D. (2021) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2020.100864 · Cited by 50 · see citing works

Effects of glyphosate exposure on honeybees

Tan, S., Li, G., Liu, Z., Wang, H., Guo, X., & Xu, B. (2021) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2021.103792 · Cited by 46 · see citing works

Isolation of β-carotene, α-carotene and lutein from carrots by countercurrent chromatography with the solvent system modifier benzotrifluoride

Englert, M., Hammann, S., & Vetter, W. (2015) · Journal of Chromatography A · doi:10.1016/j.chroma.2015.02.020 · Cited by 48 · see citing works

Anti-amyloid aggregation activity of novel carotenoids: implications for Alzheimer’s drug discovery

Lakey‐Beitia, J., Doens, D., Jagadeesh Kumar, D., Murillo, E., Fernández, P. L., Rao, K. S. J., & Durant-Archibold, A. A. (2017) · Clinical Interventions in Aging · doi:10.2147/cia.s134605 · Cited by 48 · see citing works

Multidrug resistance crisis during COVID-19 pandemic: Role of anti-microbial peptides as next-generation therapeutics

Sharma, S., Barman, P., Joshi, S., Preet, S., & Saini, A. (2021) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2021.112303 · Cited by 45 · see citing works

Brazilian tucumã-do-Amazonas (Astrocaryum aculeatum) and tucumã-do-Pará (Astrocaryum vulgare) fruits: bioactive composition, health benefits, and technological potential

Machado, A. P. D. F., do Nascimento, R. D. P., Alves, M. D. R., Reguengo, L. M., & Maróstica, M. R. (2021) · Food Research International · doi:10.1016/j.foodres.2021.110902 · Cited by 45 · see citing works

Commercialization aspects of carotenoids

Bogacz-Radomska, L., Harasym, J., & Piwowar, A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-817067-0.00010-5 · Cited by 44 · see citing works

Visible-Light-Mediated Alkenylation of Alkyl Boronic Acids without an External Lewis Base as an Activator

Yue, F., Dong, J., Liu, Y., & Wang, Q. (2021) · Organic Letters · doi:10.1021/acs.orglett.1c00399 · Cited by 43 · see citing works

N -Methylimidazolium perchlorate as a new ionic liquid for the synthesis of bis(pyrazol-5-ol)s under solvent-free conditions

Khaligh, N. G., Hamid, S. B. A., & Titinchi, S. J. J. (2015) · Chinese Chemical Letters · doi:10.1016/j.cclet.2015.07.027 · Cited by 42 · see citing works

Therapeutic modulation of retinoid X receptors – SAR and therapeutic potential of RXR ligands and recent patents

Schierle, S., & Merk, D. (2019) · Expert Opinion on Therapeutic Patents · doi:10.1080/13543776.2019.1643322 · Cited by 42 · see citing works

Aster proteins mediate carotenoid transport in mammalian cells

Bandara, S., Ramkumar, S., Imanishi, S. S., Thomas, L. D., Sawant, O. B., Imanishi, Y., & Lintig, J. V. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2200068119 · Cited by 41 · see citing works

Non-adiabatic molecular dynamics with ΔSCF excited states

Pradhan, E., Sato, K., & Akimov, A. V. (2018) · Journal of Physics Condensed Matter · doi:10.1088/1361-648x/aae864 · Cited by 41 · see citing works

Genetic dissection in a mouse model reveals interactions between carotenoids and lipid metabolism

Palczewski, G., Widjaja‐Adhi, M. A. K., Amengual, J., Golczak, M., & Lintig, J. V. (2016) · Journal of Lipid Research · doi:10.1194/jlr.m069021 · Cited by 40 · see citing works

Effect of the co-existing and excipient oil on the bioaccessibility of β-carotene loaded oil-free nanoparticles

Chen, L., Liang, R., YOKOYAMA, W. H., Alves, P. L. D. S., Pan, J., & Zhong, F. (2020) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2020.105847 · Cited by 40 · see citing works

Vitamin A bio-modulates apoptosis via the mitochondrial pathway after hypoxic-ischemic brain damage

Jiang, W., Guo, M., Gong, M., Chen, L., Bi, Y., Zhang, Y., Shi, Y., Qü, P., Liu, Y., Chen, J., et al. (2018) · Molecular Brain · doi:10.1186/s13041-018-0360-0 · Cited by 39 · see citing works

Structure-based design of Trifarotene (CD5789), a potent and selective RARγ agonist for the treatment of acne

Thoreau, É., Arlabosse, J.-M., Bouix‐Peter, C., Chambon, S., Chantalat, L., Daver, S., Dumais, L., Duvert, G., Feret, A., Ouvry, G., et al. (2018) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2018.04.036 · Cited by 38 · see citing works

Dealkenylative Alkenylation: Formal σ‐Bond Metathesis of Olefins

Swain, M., Sadykhov, G., Wang, R., & Kwon, O. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202005267 · Cited by 37 · see citing works

β‐Carotene—production methods, biosynthesis from Phaffia rhodozyma, factors affecting its production during fermentation, pharmacological properties: A review

Gupta, I., Adin, S. N., Panda, B. P., & Mujeeb, M. (2022) · Biotechnology and Applied Biochemistry · doi:10.1002/bab.2301 · Cited by 37 · see citing works

Optimization of Total Carotenoid Production by Halorubrum Sp. TBZ126 Using Response Surface Methodology

Hamidi, M. (2014) · Journal of Microbial & Biochemical Technology · doi:10.4172/1948-5948.1000158 · Cited by 37 · see citing works

Visible light-induced bromine radical enhanced hydrogen atom transfer (HAT) reactions in organic synthesis

Saxena, B., Patel, R. I., & Sharma, A. (2024) · RSC Sustainability · doi:10.1039/d4su00214h · Cited by 36 · see citing works

Encapsulation of β-Carotene in Oil-in-Water Emulsions Containing Nanocellulose: Impact on Emulsion Properties, In Vitro Digestion, and Bioaccessibility

Fitri, I. A., Mitbumrung, W., Akanitkul, P., Rungraung, N., Kemsawasd, V., Jain, S., & Winuprasith, T. (2022) · Polymers · doi:10.3390/polym14071414 · Cited by 35 · see citing works

Solvate Ionic Liquids as Reaction Media for Electrocyclic Transformations

Eyckens, D. J., Champion, M. E., Fox, B. L., Yoganantharajah, P., Gibert, Y., Welton, T., & Henderson, L. C. (2016) · European Journal of Organic Chemistry · doi:10.1002/ejoc.201501614 · Cited by 35 · see citing works

Quinolidene based monocarbonyl curcumin analogues as promising antimycobacterial agents: Synthesis and molecular docking study

Subhedar, D. D., Shaikh, M. H., Nawale, L., Sarkar, D. M., Khedkar, V. M., & Shingate, B. B. (2017) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2017.01.004 · Cited by 35 · see citing works

Marine Bacteria Is the Cell Factory to Produce Bioactive Pigments: A Prospective Pigment Source in the Ocean

Velmurugan, P., Venil, C. K., Ravi, A. V., & Dufossé, L. (2020) · Frontiers in Sustainable Food Systems · doi:10.3389/fsufs.2020.589655 · Cited by 35 · see citing works

Rhodopsins: An Excitingly Versatile Protein Species for Research, Development and Creative Engineering

DeGrip, W. J., & Ganapathy, S. (2022) · Frontiers in Chemistry · doi:10.3389/fchem.2022.879609 · Cited by 34 · see citing works

[Et3NH][HSO4] catalyzed efficient synthesis of 5-arylidene-rhodanine conjugates and their antitubercular activity

Subhedar, D. D., Shaikh, M. H., Nawale, L., Yeware, A. M., Sarkar, D. M., & Shingate, B. B. (2016) · Research on Chemical Intermediates · doi:10.1007/s11164-016-2484-0 · Cited by 32 · see citing works

Evidence that Acetonitrile is Sensitive to Different Interaction Sites of Ionic Liquids as Revealed by Excess Spectroscopy

Zhou, Y. M., Zheng, Y., Zhang, T., Deng, G., & Yu, Z. (2017) · ChemPhysChem · doi:10.1002/cphc.201601376 · Cited by 31 · see citing works

Physicochemical Properties and Chemical Stability of β-Carotene Bilayer Emulsion Coated with Bovine Serum Albumin and Arabic Gum Compared to Monolayer Emulsions

Sheng, B., Li, L., Zhang, X., Jiao, W., Zhao, D., Wang, X., Wan, L., Li, B. J., & Rong, H. (2018) · Molecules · doi:10.3390/molecules23020495 · Cited by 31 · see citing works

Study on the Synthesis, Antioxidant Properties, and Self-Assembly of Carotenoid–Flavonoid Conjugates

Línzembold, I., Czett, D., Böddi, K., Kurtán, T., Király, S. B., Gulyás‐Fekete, G., Takátsy, A., Lóránd, T., Deli, J., Agócs, A., et al. (2020) · Molecules · doi:10.3390/molecules25030636 · Cited by 30 · see citing works

Carotenoids from microalgae

Lafarga, T., Clemente, I., & García‐Vaquero, M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-817067-0.00005-1 · Cited by 30 · see citing works

Pushing the Boundaries of Vinylogous Reactivity: Catalytic Enantioselective Mukaiyama Aldol Reactions of Highly Unsaturated 2‐Silyloxyindoles

Curti, C., Sartori, A. M., Battistini, L., Brindani, N., Rassu, G., Pelosi, G., Lodola, A., Mor, M., Casiraghi, G., & Zanardi, F. (2015) · Chemistry - A European Journal · doi:10.1002/chem.201500083 · Cited by 29 · see citing works

The Therapeutic Role of Carotenoids in Diabetic Retinopathy: A Systematic Review

Fathalipour, M., Fathalipour, H., Safa, O., Nowrouzi‐Sohrabi, P., Mirkhani, H., & Hassanipour, S. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s255783 · Cited by 29 · see citing works

Key Residues for Catalytic Function and Metal Coordination in a Carotenoid Cleavage Dioxygenase

Sui, X., Zhang, J., Golczak, M., Palczewski, K., & Kiser, P. D. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.744912 · Cited by 29 · see citing works

Regulation of vitamin D receptor expression by retinoic acid receptor alpha in acute myeloid leukemia cells

Marchwicka, A., Cebrat, M., Łaszkiewicz, A., Śnieżewski, Ł., Brown, G., & Marcinkowska, E. (2016) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2016.03.013 · Cited by 27 · see citing works

Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization

Scheepstra, M., Andrei, S. A., de Vries, R. M. J. M., Meijer, F. A., Ma, J., Burstein, E. S., Olsson, R., Ottmann, C., Milroy, L. ‐., & Brunsveld, L. (2017) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.7b00216 · Cited by 28 · see citing works

“Supermarket Column Chromatography of Leaf Pigments” Revisited: Simple and Ecofriendly Separation of Plant Carotenoids, Chlorophylls, and Flavonoids from Green and Red Leaves

Dias, A., & Ferreira, M. L. S. (2014) · Journal of Chemical Education · doi:10.1021/ed500299j · Cited by 28 · see citing works

Genome–Scale Metabolic Networks Shed Light on the Carotenoid Biosynthesis Pathway in the Brown Algae Saccharina japonica and Cladosiphon okamuranus

Nègre, D., Aïte, M., Belcour, A., Frioux, C., Brillet-Guéguen, L., Liu, X., Bordron, P., Godfroy, O., Lipinska, A. P., Leblanc, C., et al. (2019) · Antioxidants · doi:10.3390/antiox8110564 · Cited by 28 · see citing works

Metabolic Pathway Coupled with Fermentation Process Optimization for High-Level Production of Retinol in Yarrowia lipolytica

Ren, X., Liu, M., Yue, M., Zeng, W., Zhou, S., Zhou, J., & Xu, S. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c00377 · Cited by 27 · see citing works

Fluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways

Chisholm, D. R., Tomlinson, C. W. E., Zhou, G.-L., Holden, C. A., Affleck, V., Lamb, R., Newling, K., Ashton, P. D., Valentine, R., Redfern, C. P. F., et al. (2019) · ACS Chemical Biology · doi:10.1021/acschembio.8b00916 · Cited by 27 · see citing works

Spirolactone and spirothiolactone rhodamine-pyrene probes for detection of Hg2+ with different sensing properties and its application in living cells

Rui, Q.-Q., Zhou, Y., Yuan, F., & Yao, C. (2016) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2016.01.024 · Cited by 27 · see citing works

The Impact of Vitamin Deficiencies on Oral Manifestations in Children

Lešić, S., Ivanišević, Z., Špiljak, B., Tomas, M., Šoštarić, M., & Včev, A. (2024) · Dentistry Journal · doi:10.3390/dj12040109 · Cited by 26 · see citing works

Highly efficient and recyclable basic ionic liquids supported on SBA-15 for the synthesis of substituted styrenes, carbinolamides, and naphthopyrans

Sarmah, B., & Srivastava, R. (2016) · Molecular Catalysis · doi:10.1016/j.molcata.2016.11.030 · Cited by 26 · see citing works

Reconstructed cell fate–regulatory programs in stem cells reveal hierarchies and key factors of neurogenesisPreprint

Mendoza-Parra, M. A., Malysheva, V., Saleem, M.-A. M., Lieb, M., Godel, A., & Gronemeyer, H. (2016) · Genome Research · doi:10.1101/gr.208926.116 · Cited by 26 · see citing works

Effective alternative strategies to combat challenges associated with MDR bacterial infections: Drug repurposing, role of artificial intelligence, and novel therapeutic options

El-Sayed, S. E., Messiha, A. A., & Zafer, M. M. (2025) · Journal of Infection and Public Health · doi:10.1016/j.jiph.2025.103058 · Cited by 25 · see citing works

Resorcinarene Induced Assembly of Carotene and Lutein into Hierarchical Superstructures

Li, L., Tuo, W., Zhu, Q., Sepehrpour, H., Yao, Y. S., Yan, C., Liu, L., Li, D., Xie, Y., Zhang, C., et al. (2020) · Journal of the American Chemical Society · doi:10.1021/jacs.0c10901 · Cited by 24 · see citing works

Tetraphenylethene‐Based cis/trans Isomers for Targeted Fluorescence Sensing and Biomedical Applications

Huang, Y., Zhang, G., Zhao, R., & Zhang, D. (2023) · Chemistry - A European Journal · doi:10.1002/chem.202300539 · Cited by 24 · see citing works

Bioaccumulation of selenium and production of carotenoids by the yeast Rhodotorula mucilaginosa

Kieliszek, M., Kot, A. M., & Kolotylo, V. (2023) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2023.102903 · Cited by 24 · see citing works

Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis

Wu, L., Chaudhary, S., Atigadda, V., Belyaeva, O., Harville, S., Elmets, C., Muccio, D., Athar, M., & Kedishvili, N. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153556 · Cited by 21 · see citing works

Exploring the Potentials of Sajana ( Moringa oleifera Lam.) as a Plant‐Based Feed Ingredient to Sustainable and Good Aquaculture Practices: An Analysis of Growth Performance and Health Benefits

Hridoy, M. A. A. M., Munny, F. J., Shahriar, F., Rahman, M. M., Islam, M. F., Kazmi, A., & Kawsar, M. A. (2025) · Aquaculture Research · doi:10.1155/are/3580123 · Cited by 22 · see citing works

Surfactant-assisted disruption and extraction for carotenoid production from a novel Dunaliella strain

Pinheiro, N., Assunção, P., Rodríguez, A., Sanromán, M. Á., & Deive, F. J. (2019) · Separation and Purification Technology · doi:10.1016/j.seppur.2019.04.083 · Cited by 22 · see citing works

Cycloisomerization of Conjugated Trienones and Isomeric 2 H -Pyrans: Unified Strategy toward Cyclopenta[ b ]furans

Riveira, M. J., Quiroga, G. N., Mata, E. G., Gandon, V., & Mischne, M. P. (2015) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.5b00818 · Cited by 21 · see citing works

Optical Coherence Tomography Assessment Before and After Vitamin Supplementation in a Patient With Vitamin A Deficiency

Sáenz-de-Viteri, M., & Sádaba, L. M. (2016) · Medicine · doi:10.1097/md.0000000000002680 · Cited by 21 · see citing works

Night Capture of Roosting Cave Birds by Neanderthals: An Actualistic Approach

Blanco, G., Sánchez-Marco, A., & Negro, J. J. (2021) · Frontiers in Ecology and Evolution · doi:10.3389/fevo.2021.733062 · Cited by 17 · see citing works

Production of carotenoids from aromatics and pretreated lignocellulosic biomass by Novosphingobium aromaticivorans

Hall, B. W., Kontur, W. S., Neri, J. C., Gille, D. M., Noguera, D. R., & Donohue, T. J. (2023) · Applied and Environmental Microbiology · doi:10.1128/aem.01268-23 · Cited by 20 · see citing works

Recent progress in carotenoid and retinoid synthesis

Ito, M., Yamano, Y., Sumiya, S., & Wada, A. (1994) · Pure and Applied Chemistry · doi:10.1351/pac199466050939 · Cited by 26 · see citing works

Chemistry of Natural Retinoids and Carotenoids: Challenges for the Future

Valla, A. R., Cartier, D., & Labia, R. (2004) · Current Organic Synthesis · doi:10.2174/1570179043485394 · Cited by 18 · see citing works

Recent progress in commercial retinoids and carotenoids

Paust, J. (1991) · Pure and Applied Chemistry · doi:10.1351/pac199163010045 · Cited by 70 · see citing works

Synthesis of 13C-labeled carotenoids and retinoids

Lugtenburg, J., Creemers, A. F. L., Verhoeven, M. A., van Wijk, A. A. C., Verdegem, P. J. E., Monnee, M. C. F., & Jansen, F. J. H. M. (1999) · Pure and Applied Chemistry · doi:10.1351/pac199971122245 · Cited by 21 · see citing works

Retinoids and carotenoids in dermatology

Vahlquist, A., & Duvic, M. A. (2007) · doi:10.3109/9781420021189?locatt=mode:legacy