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The Relation Between Attention Deficit Hyperactivity Disorder and Substance Abuse: What Role Does Conduct Disorder Play?
Abstract
This paper presents a comprehensive review of the literature examining the relation between childhood attention deficit hyperactivity disorder (ADHD) and substance abuse. A number of researchers have statistically controlled for conduct disorder (CD) when examining the ADHD-substance-abuse relation. These studies have generally found that the ADHD-substance-abuse relation disappears when the high overlap between ADHD and CD is taken into account. On this basis, one may conclude that ADHD is unimportant to substance abuse. However, there is some evidence from both empirical studies and related fields that ADHD and CD may interact to afford a higher risk for substance abuse than may either disorder alone. Thus, ADHD appears to be important to substance abuse in that it interacts with CD to increase the risk. This paper calls for more research that directly examines the joint effects of ADHD and CD on risk for substance abuse. There is also a need for more research that examines gender differences, and mechanisms of the relations among ADHD, CD, and substance abuse.
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“This is particularly important since SUD patients with comorbid ADHD often present with severe forms of SUD [209] characterised by early onset, extended duration of SUD, greater impairment and a shorter transition from substance use to dependence [172].”
From European consensus statement on diagnosis and treatment of adult ADHD: The European Network Adult ADHD (2010) · cites this paper as [209]
In the citing paper
“For example, comorbid DBD may mediate the relation between ADHD and substance use outcomes (Flory and Lynam 2003; Lee et al. 2011).”
From Risk taking and sensitivity to punishment in children with ADHD, ODD, ADHD+ODD, and controls (2011) · cites this paper as Flory and Lynam 2003
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Bagot, K. S., Berarducci, J. M., Franken, F. H., Frazier, M. J., Ernst, M., & Moolchan, E. T. (2007) · American Journal on Addictions · doi:10.1080/10550490601080100 · Cited by 13
Hurd, Y. L. (2006) · CNS Spectrums · doi:10.1017/s1092852900015005 · Cited by 13
Harty, S. C., Galanopoulos, S., Newcorn, J. H., & Halperin, J. M. (2013) · American Journal on Addictions · doi:10.1111/j.1521-0391.2013.12015.x · Cited by 12
Psychiatric comorbidity in older long-term abstinent alcoholics
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Are childhood externalizing disorders the harbinger of early-onset alcohol dependence?
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Metadata
- Authors
- Flory, K., & Lynam, D. R.
- Affiliations
- University of Kentucky (US)
- Corresponding author
- Flory, Kate
- Venue
- Clinical Child and Family Psychology Review
- Published
- 2003-03
- Volume
- 6
- Issue
- 1
- Pages
- 1-16
- ISSN
- 1096-4037 (ISSN-L)
- 1573-2827
- OpenAlex
- W267189026
- Cited by
- 139
- References
- 79
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 1 · 2020: 1 · 2019: 1 · 2018: 4 · 2017: 3 · 2016: 5 · 2015: 7 · 2014: 10 · 2013: 10 · 2012: 12
- FWCI
- 1.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Clinical Child and Family Psychology Review (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH 60104, R01MH060104)
- National Institute on Drug Abuse (1T32-DA07304-01A1, T32DA007304)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- attention deficit hyperactivity disorder, substance abuse, conduct disorder, comorbidities, risk factors, gender differences
- MeSH terms
- Adult, Attention Deficit Disorder with Hyperactivity, Child, Humans, Comorbidity, Conduct Disorder, Substance-Related Disorders
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