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Cited by 90Child Abuse and TraumaPosttraumatic Stress Disorder ResearchStress Responses and Cortisol

The DOI matches its Crossref record; 70 of the 73 references it cites were found in a registry or an index.

Clinical Perspectives on Neurobiological Effects of Psychological Trauma

Weber, Deborah A., Reynolds, Cecil R.·2004·Neuropsychology Review
DOI 10.1023/b:nerv.0000028082.13778.14
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Abstract

Physical trauma to the brain has always been known to affect brain functions and subsequent neurobiological development. Research primarily since the early 1990s has shown that psychological trauma can have detrimental effects on brain function that are not only lasting but that may alter patterns of subsequent neurodevelopment, particularly in children although developmental effects may be seen in adults as well. Childhood trauma produces a diverse range of symptoms and defining the brain's response to trauma and the factors that mediate the body's stress response systems is at the forefront of scientific investigation. This paper reviews the current evidence relating psychological trauma to anatomical and functional changes in the brain and discusses the need for accurate diagnosis and treatment to minimize such effects and to recognize their existence in developing treatment programs.

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Crossref · 10.1023/b:nerv.0000028082.13778.14

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70 of 70 references verified0 citation errors · 0 not checkable

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  • The traumatic stress response differs from the regular stress response in that the neurochemical changes, which are initially beneficial, often outlive the threat of the stressor, so hyperarousal continues even when the stressor has dissipated.

    “Importantly, the traumatic stress response (i.e. the “toxic stress response” response) differs from the regular stress response in that the neurochemical changes, which are initially beneficial, often outlive the threat of the stressor. This means that the hyperarousal state continues even when the stressor has dissipated.”

    From Childhood Trauma, the HPA Axis and Psychiatric Illnesses: A Targeted Literature Synthesis (2022) · cites this paper as [34]

Citations

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3 of the 73 references couldn’t be matched to a known paper.

Research works printed but not linked: 11

  1. Amaya-Jackson, L., and March, J. S. (1995). Posttraumatic stress disorder. In: March, J. S. (ed.), Anxiety Disorders in Children and Adolescents Guilford, New York, pp. 276-300.
  2. Bergherr, T., Bremner, J. D., Southwick, S.M., Charney, D. S., and Krystal, J. H. (1997). Neurobiological perspectives on trauma and aging. J. Geriatr. Psychiatry 30(1): 27-59.
  3. Joseph, R. (1999). The neurology of traumatic "dissociative" amnesia: Commentary and literature review. Child Abuse Negl. 22(8): 715-727.
  4. Perry, B. D. (1999). Effect of traumatic events on children. Interdiscip. Educ. Ser. 3(2): 1-22.
  5. Reynolds, C. R., and Kamphaus, R. W. (1992). The Behavior Assessment System for Children, American Guidance Service, Circle Pines, MN.
  6. Reynolds, C. R., and Kamphaus, R. W., (2002). The Clinician's Guide to the Behavior Assessment System for Children, Guilford, New York.
  7. Southwick, S. M., Krystal, J. H., Johnson, D. R., and Charney, D. S. (1992). Neurobiology of posttraumatic stress disorder. Review of Psychiatry 11: 347-367.
  8. Southwick, S. M., Yehuda, R., and Charney, D. S. (1997). Neurobiological alterations in PTSD: Review of the clinical literature. In Fullerton, C. S., and Ursano, R. J. (eds.), Posttraumatic Stress Disorder: Acute and Long-Term Responses to Trauma and Disaster American Psychiatric Press, Washington, DC, pp. 241-266.
  9. Teicher, M. H., Ito, Y., Glod, C. A., Schiffer, F., and Gelbard, H. A. (1996). Neurophysiological mechanisms of stress response in children. In Pfeffer, C. (ed.), Severe Stress and Mental Disturbance in Children, American Psychiatric Press, Washington, DC.
  10. van der Kolk, B. (1993). Biological considerations about emotions, trauma, memory, and the brain. In Ablon, S. L., Brown, D., Khantzian, E. J., and Mack, J. E. (eds.), Human Feelings: Explorations in Affect Development and Meanings, Analytic Press, Hillsdale, NJ.
  11. Wallen, S., Callaghan, M., Henry, D., and Wallen, J. (1994). Psychiatric disorders in sexually. J. Am. Acad. Child Adolesc. Psychiatry 33: 313-319. · DOI · Paper page

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Metadata

Authors
Weber, D. A., & Reynolds, C. R.
Affiliations
Texas A&M University (US)
Corresponding author
Reynolds, Cecil R.
ORCID
Reynolds, Cecil R.
Venue
Neuropsychology Review
Publisher
Springer Science and Business Media LLC
Published
2004-06
Volume
14
Issue
2
Pages
115-129
ISSN
  • 1040-7308 (ISSN-L)
  • 1573-6660
DOI
10.1023/b:nerv.0000028082.13778.14
OpenAlex
W1989409350
Cited by
89
References
73
Citations by year
2026: 1 · 2025: 1 · 2024: 5 · 2023: 2 · 2022: 3 · 2021: 5 · 2020: 4 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 9 · 2015: 2 · 2014: 4 · 2013: 3 · 2012: 9
FWCI
0.45
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Neuropsychology Review (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
  • Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Keywords
psychological trauma, neurobiological effects, childhood trauma, brain development, stress system, functional brain changes, trauma diagnosis, trauma treatment
MeSH terms
Amygdala, Attention Deficit Disorder with Hyperactivity, Child, Child Abuse, Sexual, Corpus Callosum, Hippocampus, Humans, Hydrocortisone, Stress Disorders, Post-Traumatic, Prefrontal Cortex

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