Context-processing deficits in schizophrenia: Diagnostic specificity, 4-week course, and relationships to clinical symptoms.
Abstract
Previous research on schizophrenia suggests that context-processing disturbances are one of the core cognitive deficits present in schizophia. However, it is not clear whether such deficits are specific to schizophrenia as compared with other psychotic disorders. To address this question, the authors administered a version of the AX Continuous Performance Test designed to assess context processing in a sample of healthy controls, patients with schizophrenia, and patients with other psychotic disorders. Participants were tested at index (when medication naive and experiencing their first contact with psychiatric services) and 4 weeks later, following medication treatment. At index, patients with schizophrenia and the psychotic comparison group demonstrated similar impairments in context processing. However, context-processing deficits improved in the psychotic comparison group at 4 weeks but did not improve in patients with schizophrenia.
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People in the schizophrenia spectrum fail to develop this normal bias and do not have an increase in errors of commission with increased frequency of targets.
“Interestingly, people in the schizophrenia spectrum fail to develop this normal bias and do not have an increase in errors of commission with increased frequency of targets. 34”
From Domains of cognition and their assessment (2019) · cites this paper as [34]
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Self-citation
- Authors
- Barch, D. M., Carter, C. S., MacDonald, A. W., Braver, T. S., & Cohen, J. D.
- Affiliations
- Washington University in St. Louis (US)
- Venue
- Journal of Abnormal Psychology
- Published
- 2003-02
- Volume
- 112
- Issue
- 1
- Pages
- 132-143
- ISSN
- 0021-843X (ISSN-L)
- 1939-1846
- OpenAlex
- W2151392566
- Cited by
- 255
- References
- 55
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 8 · 2023: 3 · 2022: 7 · 2021: 4 · 2020: 9 · 2019: 14 · 2018: 10 · 2017: 10 · 2016: 11 · 2015: 7 · 2014: 6 · 2013: 22 · 2012: 8
- FWCI
- 12.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Abnormal Psychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH47073, MH 45156, P50MH045156)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- schizophrenia, context processing, cognitive impairment, psychosis, diagnostic specificity, antipsychotic drugs, symptom improvement, first-episode psychosis
- MeSH terms
- Adult, Cognition Disorders, Female, Humans, Male, Neuropsychological Tests, Psychotic Disorders, Random Allocation, Reaction Time, Schizophrenia, Semantics, Sensitivity and Specificity, Antipsychotic Agents
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