Smoking withdrawal dynamics: I. Abstinence distress in lapsers and abstainers
Abstract
Smoking withdrawal reports from a clinical trial (n = 893) were submitted to hierarchical linear modeling as a cross-method replication of a heterogeneity approach to withdrawal measurement and to clarify the influence of postcessation smoking on symptom reports. Five individual difference parameters tapping distinct facets of withdrawal were derived: intercepts (mean severity), linear slope (direction and rate of change), quadratic trend (curvature), volatility (scatter) and, among lapsers, a cigarette coefficent (smoking-related deflections of symptoms). All parameters were highly variable across persons. Lapsers had more aversive symptom patterns than abstainers, and symptoms tended to be higherthan otherwise predicted on lapse days. These results reinforce the conclusion that withdrawal symptoms are highly variable and argue against discarding withdrawal data from participants who lapse.
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Increased severity of nicotine withdrawal predicts increased relapse rates.
“Nicotine withdrawal symptoms are highly variable between patients and can be quite severe, with increased severity of withdrawal being predictive of increased rates of relapse [25, 27, 128–130].”
From Mechanistic insights into nicotine withdrawal (2011) · cites this paper as [130]
Among tobacco users, withdrawal symptoms, with the exception of weight, peak during the first week of abstinence and then gradually decrease to baseline levels by two to four weeks; more recent studies have found withdrawal to be persistent and elevated for several months after quitting.
“Among tobacco users, withdrawal symptoms, with the exception of weight, peaks during the first week of abstinence and then gradually decreases to baseline levels by two to four weeks (38–40); although more recent studies have found withdrawal to be persistent and elevated for several months after quitting (41, 42).”
From Tobacco addiction (2008) · cites this paper as [41]
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- Authors
- Piasecki, T. M., Jorenby, D. E., Smith, S. S., Fiore, M. C., & Baker, T. B.
- Affiliations
- University of Missouri (US)
- University of Wisconsin–Madison (US)
- Venue
- Journal of Abnormal Psychology
- Published
- 2003-02
- Volume
- 112
- Issue
- 1
- Pages
- 3-13
- ISSN
- 0021-843X (ISSN-L)
- 1939-1846
- OpenAlex
- W2044842258
- Cited by
- 154
- References
- 40
- Citations by year
- 2026: 1 · 2024: 4 · 2023: 4 · 2022: 4 · 2021: 3 · 2020: 4 · 2019: 6 · 2018: 4 · 2017: 6 · 2016: 12 · 2015: 3 · 2014: 11 · 2013: 9 · 2012: 5
- FWCI
- 4.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Abnormal Psychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01da007580-04)
- National Institute on Drug Abuse (DA07580-03)
- National Cancer Institute (CA84724-02, P50CA084724)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
- Keywords
- nicotine withdrawal, relapse, cigarette craving, individual differences, smoking cessation
- MeSH terms
- Smoking Prevention, Administration, Cutaneous, Double-Blind Method, Humans, Nicotine, Recurrence, Substance Withdrawal Syndrome, Smoking Cessation
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