Smoking withdrawal dynamics: II. Improved tests of withdrawal-relapse relations
Abstract
In this article, the authors assessed whether continuously scaled symptom parameters derived from growth models (T. M. Piasecki et al., 2003) are linked to smoking at long-term follow-up by using data from a large-scale clinical trial (N = 893). Results revealed that higher withdrawal intercepts, positive linear slopes, and greater volatility were all positively associated with relapse, and cigarette coefficients (indicating smoking-induced withdrawal reduction) were negatively related to relapse. In models keyed around the first lapse to smoking, those destined to lapse reported more severe withdrawal during abstinence, and withdrawal patterns discriminated groups defined according to lapse duration. The findings complement earlier heterogeneity studies in implicating the pattern of changing withdrawal symptoms over time as a factor strongly associated with smoking relapse.
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Withdrawal duration and severity predict relapse in abstinent human smokers.
“Indeed, withdrawal duration and severity predict relapse in abstinent human smokers (Piasecki et al. 1998(Piasecki et al. , 2000(Piasecki et al. , 2003)).”
From Mechanisms of Nicotine Addiction (2021) · cites this paper as Piasecki et al. 2003
Increased severity of nicotine withdrawal predicts increased relapse rates.
“Nicotine withdrawal symptoms are highly variable between patients and can be quite severe, with increased severity of withdrawal being predictive of increased rates of relapse [25, 27, 128–130].”
From Mechanistic insights into nicotine withdrawal (2011) · cites this paper as [128]
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- Authors
- Piasecki, T. M., Jorenby, D. E., Smith, S. S., Fiore, M. C., & Baker, T. B.
- Affiliations
- University of Missouri (US)
- University of Wisconsin–Madison (US)
- Venue
- Journal of Abnormal Psychology
- Published
- 2003-02
- Volume
- 112
- Issue
- 1
- Pages
- 14-27
- ISSN
- 0021-843X (ISSN-L)
- 1939-1846
- OpenAlex
- W1976972165
- Semantic Scholar
- 11b91a5a50b6977fa42f8b1da0b608a6fa439524
- Cited by
- 159
- References
- 46
- Citations by year
- 2024: 3 · 2023: 1 · 2022: 6 · 2021: 5 · 2020: 7 · 2019: 4 · 2018: 7 · 2017: 5 · 2016: 12 · 2015: 5 · 2014: 9 · 2013: 16 · 2012: 7
- FWCI
- 4.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Abnormal Psychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01da007580-04)
- National Institute on Drug Abuse (DA07580-03)
- National Cancer Institute (CA84724-02, P50CA084724)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
- Keywords
- nicotine withdrawal, smoking relapse, growth models, abstinence, nicotine dependence
- MeSH terms
- Smoking Prevention, Adult, Double-Blind Method, Female, Follow-Up Studies, Humans, Male, Nicotine, Recurrence, Severity of Illness Index, Smoking, Substance Withdrawal Syndrome, Smoking Cessation, Bupropion, Dopamine Uptake Inhibitors
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