Treatment of posttraumatic stress symptoms in adolescent survivors of childhood cancer and their families: a randomized clinical trial.

Kazak, Anne E.; Alderfer, Melissa A.; Streisand, Randi; Simms, Steven; Rourke, Mary T.; Barakat, Lamia P.; Gallagher, Paul; Cnaan, Avital

doi:10.1037/0893-3200.18.3.493

Cited by 305Childhood Cancer Survivors' Quality of LifeCancer survivorship and carePosttraumatic Stress Disorder Research

Treatment of posttraumatic stress symptoms in adolescent survivors of childhood cancer and their families: a randomized clinical trial.

Kazak, Anne E., Alderfer, Melissa A., Streisand, Randi, Simms, Steven, Rourke, Mary T., Barakat, Lamia P., Gallagher, Paul, Cnaan, Avital·2004·Journal of Family Psychology

DOI 10.1037/0893-3200.18.3.493

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Abstract

Posttraumatic stress symptoms (PTSS), particularly intrusive thoughts, avoidance, and arousal, are among the most common psychological aftereffects of childhood cancer for survivors and their mothers and fathers. We conducted a randomized wait-list control trial of a newly developed 4-session, 1-day intervention aimed at reducing PTSS that integrates cognitive-behavioral and family therapy approaches--the Surviving Cancer Competently Intervention Program (SCCIP). Participants were 150 adolescent survivors and their mothers, fathers, and adolescent siblings. Significant reductions in intrusive thoughts among fathers and in arousal among survivors were found in the treatment group. A multiple imputations approach was used to address nonrandom missing data and indicated that treatment effects would likely have been stronger had more distressed families been retained. The data are supportive of brief interventions to reduce PTSS in this population and provide additional support for the importance of intervention for multiple members of the family.

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Engaging parents within a tertiary hospital setting has been recognized as particularly challenging.
“Engaging parents within a tertiary hospital setting has been recognized as particularly challenging.20,23,44,46”
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Barriers to attending face-to-face programs include recurrent illness and/or ongoing disability in the child, time, childcare and financial pressures, and a preference to spend time at home following family separations.
“Barriers to attending face-to-face programs include recurrent illness and/or ongoing disability in the child, time, childcare and financial pressures that have arisen from the child’s illness, and a preference to spend time at home following family separations associated with the child’s hospitalization [22–24].”
From Take A Breath: Study protocol for a randomized controlled trial of an online group intervention to reduce traumatic stress in parents of children with a life threatening illness or injury (2016) · cites this paper as [23]
Research with parents of ill children has found problematic levels of uptake and attendance for group interventions.
“Research with parents of ill children has found problematic levels of uptake and attendance for group interventions [23].”
From Take A Breath: Study protocol for a randomized controlled trial of an online group intervention to reduce traumatic stress in parents of children with a life threatening illness or injury (2016) · cites this paper as [23]

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Authors: Kazak, A. E., Alderfer, M. A., Streisand, R., Simms, S., Rourke, M. T., Barakat, L. P., Gallagher, P., & Cnaan, A.
Affiliations: Children's Hospital of Philadelphia (US)
Drexel University (US)
ORCID: Kazak, Anne E.
Alderfer, Melissa A.
Streisand, Randi
Barakat, Lamia P.
Cnaan, Avital
Venue: Journal of Family Psychology
Publisher: American Psychological Association (APA)
Published: 2004-09
Volume: 18
Issue: 3
Pages: 493-504
ISSN: 0893-3200 (ISSN-L)
1939-1293
DOI: 10.1037/0893-3200.18.3.493
OpenAlex: W1975840898
Cited by: 303
References: 56
Citations by year: 2026: 12 · 2025: 9 · 2024: 10 · 2023: 12 · 2022: 12 · 2021: 15 · 2020: 12 · 2019: 17 · 2018: 7 · 2017: 11 · 2016: 16 · 2015: 20 · 2014: 14 · 2013: 11 · 2012: 22
FWCI: 13.53
Type: journal article
Language: en
Open access: closed
Locations: Journal of Family Psychology (publishedVersion)
PubMed (publishedVersion)
Funders: National Cancer Institute (CA-15488, R01CA063930, CA63930, U10CA015488)
Topics: Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
Health Sciences › Medicine › Oncology › Cancer survivorship and care
Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
Keywords: posttraumatic stress symptoms, childhood cancer survivors, adolescents, family therapy, cognitive behavioral therapy, brief intervention, intrusive thoughts, hyperarousal, avoidance, parents of cancer survivors, siblings, multiple imputation
MeSH terms: Adaptation, Psychological, Adolescent, Arousal, Child, Family Therapy, Female, Humans, Longitudinal Studies, Male, Neoplasms, Parents, Stress Disorders, Post-Traumatic, Cognitive Behavioral Therapy, Treatment Outcome, Survivors

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Treatment of posttraumatic stress symptoms in adolescent survivors of childhood cancer and their families: a randomized clinical trial.

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