The effects of nicotine on intrusive memories in nonsmokers
Abstract
Correlational research suggests that smoking increases risk of posttraumatic stress disorder (PTSD), though such research by nature cannot rule out third variable explanations for this relationship. The present study used an analogue trauma film design to experimentally test the effects of nicotine on the occurrence of intrusive memories. Fifty-four healthy nonsmokers were randomly assigned to ingest either a nicotine or placebo lozenge before viewing a film depicting motor vehicle accidents. Participants recorded intrusive memories immediately after the film and for a week via diary. Participants in the nicotine condition reported significantly more intrusive memories immediately after watching the film, yet no group differences emerged on intrusions or intrusion-related distress reported during the following week. Among participants low in dispositional rumination, those who had ingested a nicotine lozenge reported more intrusions in the subsequent week than those in the placebo condition. These findings provide novel experimental evidence for the role of nicotine in increasing risk of PTSD and suggest that nicotine may contribute to trauma-related rumination but not heightened reactivity to trauma cues.
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Rumination after a trauma film increased the experience of intrusions and intrusion-related distress.
“a number of experimental studies have found that rumination (versus, for example, distraction) after a trauma film increased the experience of intrusions and intrusion-related distress”
From Intrusive memories of trauma: A target for research bridging cognitive science and its clinical application (2019) · cites this paper as Hawkins & Cougle, 2013
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- Authors
- Hawkins, K. A., & Cougle, J. R.
- ORCID
- Cougle, Jesse R.
- Venue
- Experimental and Clinical Psychopharmacology
- Published
- 2013-12
- Volume
- 21
- Issue
- 6
- Pages
- 434-442
- ISSN
- 1064-1297 (ISSN-L)
- 1936-2293
- OpenAlex
- W2128562480
- Cited by
- 24
- References
- 40
- Citations by year
- 2024: 2 · 2023: 1 · 2022: 1 · 2021: 2 · 2019: 3 · 2018: 8 · 2016: 3 · 2015: 4
- FWCI
- 2.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Experimental and Clinical Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Keywords
- nicotine, intrusive memories, post-traumatic stress disorder, non-smokers, motor vehicle accidents, nicotine lozenges
- MeSH terms
- Administration, Oral, Adolescent, Affect, Analysis of Variance, Anxiety, Female, Humans, Male, Memory, Nicotine, Surveys and Questionnaires, Recurrence, Chi-Square Distribution, Recognition, Psychology, Memory, Episodic, Healthy Volunteers
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