Predictors of lapse in first week of smoking abstinence in PTSD and non-PTSD smokers
Open accessAbstract
INTRODUCTION: Retrospective research suggests smokers with posttraumatic stress disorder (PTSD) lapse more quickly after their quit date. Ecological momentary assessment (EMA) research is needed to confirm the presence of early smoking lapse in PTSD and form conceptualizations that inform intervention. METHODS: Smokers with (n = 55) and without (n = 52) PTSD completed alarm-prompted EMA of situational and psychiatric variables the week before and after a quit date, and self-initiated EMA following smoking lapses. Blood samples at baseline and on the quit date allowed assessment of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA(S)). RESULTS: PTSD was related to shorter time to lapse (hazard ratio [HR] = 1.677, 95% CI: 1.106-2.544). Increased smoking abstinence self-efficacy was related to longer time to lapse (HR = 0.608, 95% CI: 0.430-0.860). Analyses of participants' real-time reports revealed that smokers with PTSD were more likely to attribute first-time lapses to negative affect ( = 5.412, p = .020), and trauma reminders (Fisher's exact p = .003**). Finally, the quit date decrease in DHEA(S) was related to shorter time to lapse (HR = 1.009, 95% CI: 1.000-1.018, p < .05). CONCLUSIONS: Results provide evidence of shorter time to first smoking lapse in PTSD, and add to evidence that early lapse occasions are more strongly related to trauma reminders, negative affect, and cravings in smokers with PTSD.
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Most PTSD patients reinitiate smoking to alleviate their symptoms.
“Therefore, most PTSD patients reinitiate smoking to alleviate their symptoms (Beckham et al., 2012).”
From Nicotine addiction and psychiatric disorders (2015) · cites this paper as Beckham et al., 2012
Human studies suggest that smoking may alleviate symptoms associated with anxiety disorders, while nicotine abstinence worsens those symptoms and results in higher rates of reinitiation of smoking.
“While human studies suggest that smoking may alleviate the symptoms associated with anxiety disorders (Beckham et al., 2005; Feldner et al., 2007; Greenberg et al., 2012; Thorndike et al., 2006), nicotine abstinence worsens those symptoms (Dedert et al., 2011) and results in higher rates of reinitiation of smoking (Beckham et al., 2012; Hapke et al., 2005; Lasser et al., 2000).”
From Nicotine addiction and psychiatric disorders (2015) · cites this paper as Beckham et al., 2012
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- Authors
- Beckham, J. C., Calhoun, P. S., Dennis, M. F., Wilson, S. M., & Dedert, E. A.
- Affiliations
- Durham VA Medical Center (US)
- Duke Medical Center (US)
- Duke University (US)
- Venue
- Nicotine & Tobacco Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-11-22
- Volume
- 15
- Issue
- 6
- Pages
- 1122-1129
- ISSN
- 1462-2203 (ISSN-L)
- 1469-994X
- PMC
- PMC3646653
- OpenAlex
- W2319587327
- Cited by
- 61
- References
- 43
- Citations by year
- 2024: 3 · 2023: 5 · 2022: 2 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 6 · 2017: 3 · 2016: 7 · 2015: 15 · 2014: 8 · 2013: 3
- FWCI
- 5.58
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Nicotine & Tobacco Research (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- U.S. Department of Veterans Affairs
- National Institutes of Health (5k24da016388-10)
- National Institute on Drug Abuse (K24-DA-016388, R21DA019704, 5K24DA016388)
- National Cancer Institute (R01CA081595, R21CA128965)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- post-traumatic stress disorder, smoking cessation, smoking relapse, early abstinence, trauma reminders, negative affect, nicotine craving, dehydroepiandrosterone sulfate, dehydroepiandrosterone
- MeSH terms
- Smoking Prevention, Adolescent, Adult, Aged, Dehydroepiandrosterone, Demography, Female, Humans, Male, Middle Aged, Recurrence, Retrospective Studies, Smoking, Stress Disorders, Post-Traumatic, Time Factors, Case-Control Studies, Smoking Cessation, Dehydroepiandrosterone Sulfate, Self Efficacy, Young Adult
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