Drosophila Toll and IL-1 receptor

Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the Lps Gene Product

Hoshino, K., Takeuchi, O., Kawai, T., Sanjo, H., Ogawa, T., Takeda, Y., Takeda, K., & Akira, S. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.7.3749 · Cited by 3,374

Toll-like Receptors and the Control of Immunity

Fitzgerald, K. A., & Kagan, J. C. (2020) · Cell · doi:10.1016/j.cell.2020.02.041 · Cited by 2,168

Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction

Chow, J. C., Young, D. W., Golenbock, D. T., Christ, W. J., & Gusovsky, F. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.16.10689 · Cited by 1,924

Overview of the IL ‐1 family in innate inflammation and acquired immunity

Dinarello, C. A. (2018) · Immunological Reviews · doi:10.1111/imr.12621 · Cited by 1,866

The history of toll-like receptors - redefining innate immunity

O'Neill, L. A. J., Golenbock, D., & Bowie, A. G. (2013) · Nature reviews. Immunology · doi:10.1038/nri3446 · Cited by 1,765

Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action

TURNBULL, A. V., & RIVIER, C. L. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.1.1 · Cited by 1,297

Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4

Pålsson‐McDermott, E. M., & O'Neill, L. A. J. (2004) · Immunology · doi:10.1111/j.1365-2567.2004.01976.x · Cited by 1,254

Transcriptional Regulation by Extracellular signals: Mechanisms and Specificity

Hill, C. S., & Treisman, R. (1995) · Cell · doi:10.1016/0092-8674(95)90403-4 · Cited by 1,012

TLRs and innate immunity

Beutler, B. A. (2009) · Blood · doi:10.1182/blood-2008-07-019307 · Cited by 840

MyD88: a central player in innate immune signaling

Deguine, J., & Barton, G. M. (2014) · F1000Prime Reports · doi:10.12703/p6-97 · Cited by 692

Lipoteichoic Acid (LTA) of Streptococcus pneumoniaeand Staphylococcus aureus Activates Immune Cells via Toll-like Receptor (TLR)-2, Lipopolysaccharide-binding Protein (LBP), and CD14, whereas TLR-4 and MD-2 Are Not Involved

Schröder, N. W. J., Morath, S., Alexander, C., Hamann, L., Hartung, T., Zähringer, U., Göbel, U. B., Weber, J. R., & Schumann, R. R. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212829200 · Cited by 641

Innate immune recognition of the microbiota promotes host-microbial symbiosis

Chu, H., & Mazmanian, S. K. (2013) · Nature Immunology · doi:10.1038/ni.2635 · Cited by 630

The role of the innate immune system in psychiatric disorders

Jones, K. A., & Thomsen, C. (2013) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2012.10.002 · Cited by 274

Sweeten PAMPs: Role of sugar complexed PAMPs in innate immunity and vaccine biology

Mahla, R. S. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00248 · Cited by 239

PU.1 and Interferon Consensus Sequence-binding Protein Regulate the Myeloid Expression of the Human Toll-like Receptor 4 Gene

Rehli, M., Poltorak, A., Schwarzfischer, L., Krause, S. W., Andreesen, R., & Beutler, B. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.13.9773 · Cited by 233

The Two NF-κB Pathways Regulating Bacterial and WSSV Infection of Shrimp

Li, C., Wang, S., & He, J. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01785 · Cited by 230

Dysregulation of human Toll-like receptor function in aging

Shaw, A. C., Panda, A., Joshi, S. R., Qian, F., Allore, H. G., & Montgomery, R. R. (2011) · Ageing Research Reviews · doi:10.1016/j.arr.2010.10.007 · Cited by 215

Innate immunity and antimicrobial defense systems in psoriasis

Büchau, A. S., & Gallo, R. L. (2007) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2007.08.016 · Cited by 169

Toll-like Receptor 4 and Hepatic Fibrogenesis

Pradere, J.-P., Troeger, J., Dapito, D., Mencin, A., & Schwabe, R. (2010) · Seminars in Liver Disease · doi:10.1055/s-0030-1255353 · Cited by 158

TLRs: Professor Mechnikov, sit on your hat

O'Neill, L. A. J. (2004) · Trends in Immunology · doi:10.1016/j.it.2004.10.005 · Cited by 140

The Interleukin‐1 Receptor Family

Boraschi, D., & Tagliabue, A. (2006) · Vitamins & Hormones · doi:10.1016/s0083-6729(06)74009-2 · Cited by 133

A gradient of cytoplasmic Cactus degradation establishes the nuclear localization gradient of the dorsal morphogen in Drosophila

Bergmann, A., Stein, D., Geisler, R., Hagenmaier, S., Schmid, B., Fernandez, N., Schnell, B., & Nüsslein-Volhard, C. (1996) · Mechanisms of Development · doi:10.1016/s0925-4773(96)00607-7 · Cited by 119

Polyamines are required for expression of Toll-like receptor 2 modulating intestinal epithelial barrier integrity

Chen, J., Rao, J. N., Zou, T., Liu, L., Marasa, B. S., Xiao, L., Zeng, X., Turner, D. J., & Wang, J.-Y. (2007) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00201.2007 · Cited by 107

IL1 receptor accessory protein like, a protein involved in X-linked mental retardation, interacts with Neuronal Calcium Sensor-1 and regulates exocytosis

Bahi, N. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg147 · Cited by 105

Highly diversified innate receptor systems and new forms of animal immunity

Messier-Solek, C., Buckley, K. M., & Rast, J. P. (2010) · Seminars in Immunology · doi:10.1016/j.smim.2009.11.007 · Cited by 87

Finding a Toll on the Route: The Fate of Osteoclast Progenitors After Toll-Like Receptor Activation

Souza, P. P. C., & Lerner, U. H. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01663 · Cited by 67