miRNAs control insulin content in pancreatic β‐cells via downregulation of transcriptional repressors

MicroRNAs: Target Recognition and Regulatory Functions

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The nuclear RNase III Drosha initiates microRNA processing

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The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells

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MicroRNA-24 Regulates Vascularity After Myocardial Infarction

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MicroRNA-mediated regulation of glucose and lipid metabolism

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MicroRNA-7a regulates pancreatic β cell function

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Thioredoxin-interacting protein regulates insulin transcription through microRNA-204

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MicroRNAs in Metabolic Disease

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Mechanisms of β-cell dedifferentiation in diabetes: recent findings and future research directions

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MicroRNAs in Vascular and Metabolic Disease

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Influence of miRNA in insulin signaling pathway and insulin resistance: micro‐molecules with a major role in type‐2 diabetes

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miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development

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Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes

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MicroRNAs in Obesity and Related Metabolic Disorders

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How to make a functional β-cell

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The miRNA Profile of Human Pancreatic Islets and Beta-Cells and Relationship to Type 2 Diabetes Pathogenesis

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MicroRNA-7 Regulates the mTOR Pathway and Proliferation in Adult Pancreatic β-Cells

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A miR-19 regulon that controls NF-κB signaling

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Pancreas-enriched miRNAs are altered in the circulation of subjects with diabetes: a pilot cross-sectional study

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MicroRNAs as stress regulators in pancreatic beta cells and diabetes

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MicroRNA expression profiles and type 1 diabetes mellitus: systematic review and bioinformatic analysis

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MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion

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The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity

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Pancreatic β cell microRNA-26a alleviates type 2 diabetes by improving peripheral insulin sensitivity and preserving β cell function

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Regulatory Roles of MicroRNAs in Diabetes

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Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4

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The Vasculature in Prediabetes

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Beta-Cell Specific Deletion of Dicer1 Leads to Defective Insulin Secretion and Diabetes Mellitus

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MicroRNA, Nutrition, and Cancer Prevention

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MicroRNA-30d Induces Insulin Transcription Factor MafA and Insulin Production by Targeting Mitogen-activated Protein 4 Kinase 4 (MAP4K4) in Pancreatic β-Cells

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Functional Transcriptomics in Diverse Intestinal Epithelial Cell Types Reveals Robust MicroRNA Sensitivity in Intestinal Stem Cells to Microbial Status

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MicroRNA Expression in Alpha and Beta Cells of Human Pancreatic Islets

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A unique plasma microRNA profile defines type 2 diabetes progression

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Epigenetics: The missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes

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Addressing Bias in Small RNA Library Preparation for Sequencing: A New Protocol Recovers MicroRNAs that Evade Capture by Current Methods

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Postnatal β-cell maturation is associated with islet-specific microRNA changes induced by nutrient shifts at weaning

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Pancreas-enriched miRNA refines endocrine cell differentiation

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The small RNA miR-375 – a pancreatic islet abundant miRNA with multiple roles in endocrine beta cell function

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MiR-103 Controls Milk Fat Accumulation in Goat (Capra hircus) Mammary Gland during Lactation

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Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis

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β-Cell MicroRNAs: Small but Powerful

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MicroRNAs as Haematopoiesis Regulators

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MicroRNA-24/MODY Gene Regulatory Pathway Mediates Pancreatic β-Cell Dysfunction

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Role of miRNAs in the pathogenesis and susceptibility of diabetes mellitus

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MicroRNA-7: A miRNA with expanding roles in development and disease

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miR‐148a promotes plasma cell differentiation and targets the germinal center transcription factors Mitf and Bach2

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Codelivery of STAT3 siRNA and BV6 by carboxymethyl dextran trimethyl chitosan nanoparticles suppresses cancer cell progression

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Simultaneous miRNA and mRNA transcriptome profiling of human myoblasts reveals a novel set of myogenic differentiation-associated miRNAs and their target genes

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Emerging roles of non‐coding RNAs in pancreatic β‐cell function and dysfunction

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MicroRNAs as pharmacological targets in diabetes

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Cardiovascular Importance of the MicroRNA‐23/27/24 Family

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MicroRNAs as regulators of beta‐cell function and dysfunction

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Circulating microRNA levels predict residual beta cell function and glycaemic control in children with type 1 diabetes mellitus

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Role of non‐coding RNA s in pancreatic beta‐cell development and physiology

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Mechanisms of MicroRNAs in Atherosclerosis

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MicroRNAs -the Next Generation Therapeutic Targets in Human Diseases

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DICER Inactivation Identifies Pancreatic β-Cell “Disallowed” Genes Targeted by MicroRNAs

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A comparative analysis of high-throughput platforms for validation of a circulating microRNA signature in diabetic retinopathy

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MiR-132 controls pancreatic beta cell proliferation and survival through Pten/Akt/Foxo3 signaling

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MiR-375 Promotes Redifferentiation of Adult Human β Cells Expanded In Vitro

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miRNAs: novel regulators of autoimmunity-mediated pancreatic β-cell destruction in type 1 diabetes

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Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development

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Role of miRNAs in the pathogenesis of T2DM, insulin secretion, insulin resistance, and β cell dysfunction: the story so far

Kaur, P., Kotru, S., Singh, S., Behera, B. S., & Munshi, A. (2020) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-020-00760-2 · Cited by 69

MicroRNAs in islet hormone secretion

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Epigenetics and Cellular Metabolism

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Dysregulation of Dicer1 in Beta Cells Impairs Islet Architecture and Glucose Metabolism

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Functional Role of MiRNA in Cardiac Resynchronization Therapy

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A Brief Review of the Mechanisms of β-Cell Dedifferentiation in Type 2 Diabetes

Khin, P. P., Lee, J., & Jun, H. (2021) · Nutrients · doi:10.3390/nu13051593 · Cited by 62

MiRNAs in β-Cell Development, Identity, and Disease

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A Comprehensive Molecular Characterization of the Pancreatic Neuroendocrine Tumor Cell Lines BON-1 and QGP-1

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miRNA-30a-5p-mediated silencing of Beta2/NeuroD expression is an important initial event of glucotoxicity-induced beta cell dysfunction in rodent models

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MicroRNAs in Mesenteric Lymph and Plasma During Acute Pancreatitis

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MicroRNA Networks in Pancreatic Islet Cells: Normal Function and Type 2 Diabetes

Eliasson, L., & Esguerra, J. L. S. (2020) · Diabetes · doi:10.2337/dbi19-0016 · Cited by 58

Stem cell approaches for diabetes: towards beta cell replacement

Weir, G. C., Cavelti‐Weder, C., & Bonner‐Weir, S. (2011) · Genome Medicine · doi:10.1186/gm277 · Cited by 60

Serum miRNA levels are related to glucose homeostasis and islet autoantibodies in children with high risk for type 1 diabetes

Åkerman, L., Casas, R., Ludvigsson, J., Tavira, B., & Skoglund, C. (2018) · PLoS ONE · doi:10.1371/journal.pone.0191067 · Cited by 58

miR-25 and miR-92a regulate insulin I biosynthesis in rats

Karolina, D. S., Sepramaniam, S., Tan, H. Z., Armugam, A., & Jeyaseelan, K. (2013) · RNA Biology · doi:10.4161/rna.25557 · Cited by 58

The interplay between noncoding RNAs and insulin in diabetes

Tian, Y., Xu, J. M., Du, X., & Fu, X. (2018) · Cancer Letters · doi:10.1016/j.canlet.2018.01.038 · Cited by 57

Non-Coding RNA as Biomarkers for Type 2 Diabetes Development and Clinical Management

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Relevance of microRNA in metabolic diseases

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Deubiquitinase OTUD3 regulates metabolism homeostasis in response to nutritional stresses

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(Re)generating Human Beta Cells: Status, Pitfalls, and Perspectives

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Circulating miR‐146a, miR‐34a and miR‐375 in type 2 diabetes patients, pre‐diabetic and normal‐glycaemic individuals in relation to β‐cell function, insulin resistance and metabolic parameters

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Role of islet microRNAs in diabetes: which model for which question?

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Matched miRNA and mRNA signatures from a hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions

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miR-24 regulates menin in the endocrine pancreas

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