A dicer-independent miRNA biogenesis pathway that requires Ago catalysis
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AGO2 is indispensable for Dicer-independent miRNA biogenesis.
“Among the four members in the AGO family in human and mouse, only AGO2 exhibits endoneuclase activity (Meister et al., 2004, Ikeda et al., 2006) and is indispensible for Dicer-independent miRNA biogenesis (Cheloufi et al., 2010).”
From Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain (2012) · cites this paper as Cheloufi et al., 2010
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- Authors
- Cheloufi, S., Dos Santos, C. O., Chong, M. M. W., & Hannon, G. J.
- Venue
- Nature
- Published
- 2010-04-27
- Volume
- 465
- Issue
- 7298
- Pages
- 584-589
- ISSN
- 0028-0836
- 1476-4687
- PMC
- PMC2995450
- Cited by
- 1,026
- References
- 0
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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