Effect of a lifestyle intervention on change in cardiorespiratory fitness in adults with type 2 diabetes: results from the Look AHEAD Study

Look AHEAD Study Group; Jakicic, J M; Jaramillo, S A; Balasubramanyam, A; Bancroft, B; Curtis, J M; Mathews, A; Pereira, M; Regensteiner, J G; Ribisl, P M

doi:10.1038/ijo.2008.280

Cited by 145Physical Activity and HealthDiabetes, Cardiovascular Risks, and LipoproteinsCardiovascular and exercise physiology

Effect of a lifestyle intervention on change in cardiorespiratory fitness in adults with type 2 diabetes: results from the Look AHEAD Study

Open access

Look AHEAD Study Group, Jakicic, J M, Jaramillo, S A, Balasubramanyam, A, Bancroft, B, Curtis, J M, Mathews, A, Pereira, M +2 more·2009·International Journal of Obesity

DOI 10.1038/ijo.2008.280PMC PMC2656590

Open this paper in CoChat — free account

Abstract

Objective To examine the effect of an intensive lifestyle weight loss intervention (ILI) compared to diabetes support and education (DSE) on changes in fitness and physical activity in the Look AHEAD trial.Design Randomized clinical trial to compare a lifestyle intervention for weight loss with a DSE condition in individuals with type 2 diabetes.Subjects Data from 4376 overweight or obese adults with type 2 diabetes (age=58.7+/-6.8 years, body mass index (BMI)=35.8+/-5.8 kg/m(2)) who completed 1 year of the Look AHEAD trial and had available fitness data were analyzed.Intervention Subjects were randomly assigned to DSE or ILI. DSE received standard care plus three education sessions over the 1-year period. ILI included individual and group contact throughout the year, restriction in energy intake and 175 min per week of prescribed physical activity.Measurements Fitness was assessed using a submaximal graded exercise test. Physical activity was assessed by questionnaire in a subset of 2221 subjects.Results Change in fitness was statistically greater in ILI vs DSE after adjustment for baseline fitness (20.9 vs 5.7%; P<0.0001). Multivariate analysis showed that change in fitness was greater in overweight vs obese Class II and III (P<0.05). Physical activity increased by 892+/-1694 kcal per week in ILI vs 108+/-1254 kcal per week in DSE (P<0.01). Changes in fitness (r=0.41) and physical activity (r=0.42) were significantly correlated with weight loss (P<0.0001).Conclusions The ILI was effective in increasing physical activity and improving cardiorespiratory fitness in overweight and obese individuals with type 2 diabetes. This effect may add to weight loss in improving metabolic control in patients in lifestyle intervention programs.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1038/ijo.2008.280

Cites

24 of 24 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: The evidence report
(1998) · PsycEXTRA Dataset · doi:10.1037/e565682010-001 · Cited by 9,452 · see citing works
Prevalence of Overweight and Obesity in the United States, 1999-2004
Ogden, C. L., Carroll, M. D., Curtin, L. R., McDowell, M. A., Tabak, C. J., & Flegal, K. M. (2006) · JAMA · doi:10.1001/jama.295.13.1549 · Cited by 8,720 · see citing works
Physical Activity and Health: A Report of the Surgeon General
(1995) · PsycEXTRA Dataset · doi:10.1037/e525162010-001 · Cited by 5,488 · see citing works
Prevalence of Overweight and Obesity in the United States
Crespo, C. J., & Smit, E. (2003) · Human Kinetics eBooks · doi:10.5040/9781718206601.ch-001 · Cited by 4,382 · see citing works
Obesity and Cardiovascular Disease: Pathophysiology, Evaluation, and Effect of Weight Loss: An Update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease From the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism
Poirier, P., Giles, T. D., Bray, G. A., Hong, Y., Stern, J. S., Pi-Sunyer, F. X., & Eckel, R. H. (2006) · Circulation · doi:10.1161/circulationaha.106.171016 · Cited by 3,165 · see citing works
Physical Activity, All-Cause Mortality, and Longevity of College Alumni
Paffenbarger, R. S., Hyde, R., Wing, A. L., & Hsieh, C.-C. (1986) · New England Journal of Medicine · doi:10.1056/nejm198603063141003 · Cited by 2,742 · see citing works
Untitled work
(1998) · PubMed · Cited by 2,737 · see citing works
Reduction in Weight and Cardiovascular Disease Risk Factors in Individuals With Type 2 Diabetes
The Look AHEAD Research Group (2007) · Diabetes Care · doi:10.2337/dc07-0048 · Cited by 1,522 · see citing works
Guidelines for Exercise Testing and Prescription
Sharp, N. C. C. (1993) · British Journal of Sports Medicine · doi:10.1136/bjsm.27.2.138-a · Cited by 1,190 · see citing works
The Look AHEAD Study: A Description of the Lifestyle Intervention and the Evidence Supporting It
The Look AHEAD Research Group (2006) · Obesity · doi:10.1038/oby.2006.84 · Cited by 873 · see citing works
Dose–response issues concerning physical activity and health: an evidence-based symposium
ANTERO KESANIEMI (Chair), Y., DANFORTH, E., JENSEN, M. D., KOPELMAN, P. G., LEF??BVRE, P., & REEDER, B. A. (2001) · Medicine and Science in Sports and Exercise · doi:10.1097/00005768-200106001-00003 · Cited by 843 · see citing works
Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes
The Look AHEAD Research Group (2003) · Controlled Clinical Trials · doi:10.1016/s0197-2456(03)00064-3 · Cited by 767 · see citing works
The Epidemic of Obesity
Stein, C. J., & Colditz, G. A. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0288 · Cited by 635 · see citing works
Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus
Haddad, E., Wells, G. A., Sigal, R. J., Boul�, N. G., & Kenny, G. P. (2003) · Diabetologia · doi:10.1007/s00125-003-1160-2 · Cited by 601 · see citing works
Cardiorespiratory fitness and body mass index as predictors of cardiovascular disease mortality among men with diabetes
Church, T. S., LaMonte, M. J., Barlow, C. E., & Blair, S. N. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.18.2114 · Cited by 445 · see citing works
Exercise without weight loss is an effective strategy for obesity reduction in obese individuals with and without Type 2 diabetes
Lee, S., Kuk, J. L., Davidson, L. E., Hudson, R., Kilpatrick, K., Graham, T. E., & Ross, R. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00053.2005 · Cited by 348 · see citing works
The Relation of Body Mass Index, Cardiorespiratory Fitness, and All‐Cause Mortality in Women
Farrell, S. W., Braun, L., Barlow, C. E., Cheng, Y. J., & Blair, S. N. (2002) · Obesity Research · doi:10.1038/oby.2002.58 · Cited by 233 · see citing works
Cardiorespiratory Fitness Attenuates Metabolic Risk Independent of Abdominal Subcutaneous and Visceral Fat in Men
Lee, S., Kuk, J. L., Katzmarzyk, P. T., Blair, S. N., Church, T. S., & Ross, R. (2005) · Diabetes Care · doi:10.2337/diacare.28.4.895 · Cited by 231 · see citing works
The relative contributions of different levels of overweight and obesity to the increased prevalence of diabetes in the United States: 1976–2004
Gregg, E. W., Cheng, Y. J., Narayan, K. M. V., Thompson, T. J., & Williamson, D. F. (2007) · Preventive Medicine · doi:10.1016/j.ypmed.2007.07.020 · Cited by 185 · see citing works
Effects of exercise on glucose homeostasis in Type 2 diabetes mellitus
Kelley, D. E., & Goodpaster, B. H. (2001) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200106001-00020 · Cited by 168 · see citing works
Physical fitness, mortality and obesity.
Barlow, C. E., Kohl, H. W., Gibbons, L. W., & Blair, S. N. (1995) · PubMed · Cited by 164 · see citing works
Exercise Capacity and Cardiovascular/Metabolic Characteristics of Overweight and Obese Individuals With Type 2 Diabetes
Ribisl, P. M., Lang, W., Jaramillo, S. A., Jakicic, J. M., Stewart, K. J., Bahnson, J. L., Bright, R., Curtis, J. F., Crow, R. S., & Soberman, J. E. (2007) · Diabetes Care · doi:10.2337/dc06-2487 · Cited by 95 · see citing works
Self-citation
Comparison of the effect of multiple short-duration with single long-duration exercise sessions on glucose homeostasis in type 2 diabetes mellitus
Eriksen, J. G., Dahl‐Petersen, I. K., Haugaard, S. B., & Dela, F. (2007) · Diabetologia · doi:10.1007/s00125-007-0783-0 · Cited by 87 · see citing works
Six months of aerobic exercise does not improve microvascular function in type 2 diabetes mellitus
Middlebrooke, A. R., Elston, L. M., MacLeod, K. M., Mawson, D., Ball, C. I., Shore, A. C., & Tooke, J. E. (2006) · Diabetologia · doi:10.1007/s00125-006-0361-x · Cited by 77 · see citing works

Flagged first, then by citations

Sorted by citations

Physical Activity Advice Only or Structured Exercise Training and Association With HbA <sub>1c</sub> Levels in Type 2 Diabetes: A Systematic Review and Meta-analysis
Umpierre, D. (2011) · JAMA · doi:10.1001/jama.2011.576 · Cited by 1,358 · see citing works
Diabetes in Older Adults
Kirkman, M. S., Briscoe, V. J., Clark, N., Florez, H., Haas, L. B., Halter, J. B., Huang, E. S., Korytkowski, M. T., Munshi, M. N., Odegard, P. S., et al. (2012) · Diabetes Care · doi:10.2337/dc12-1801 · Cited by 1,274 · see citing works
Long-term Effects of a Lifestyle Intervention on Weight and Cardiovascular Risk Factors in Individuals With Type 2 Diabetes Mellitus: Four-Year Results of the Look AHEAD Trial
(2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2010.334 · Cited by 1,162 · see citing works
Effective behaviour change techniques for physical activity and healthy eating in overweight and obese adults; systematic review and meta-regression analyses
Samdal, G. B., Eide, G. E., Barth, T., Williams, G., & Meland, E. (2017) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/s12966-017-0494-y · Cited by 788 · see citing works
Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the Look AHEAD randomised clinical trial
(2016) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(16)30162-0 · Cited by 738 · see citing works
Self-citation
Diabetes in Older Adults: A Consensus Report
Sue Kirkman, M., Briscoe, V. J., Clark, N., Florez, H., Haas, L. B., Halter, J. B., Huang, E. S., Korytkowski, M. T., Munshi, M. N., Odegard, P. S., et al. (2012) · Journal of the American Geriatrics Society · doi:10.1111/jgs.12035 · Cited by 548 · see citing works
One-year weight losses in the Look AHEAD study: factors associated with success
Wadden, T. A., West, D. S., Neiberg, R. H., Wing, R. R., Ryan, D. H., Johnson, K. C., Foreyt, J. P., Hill, J. O., Trence, D. L., Vitolins, M. Z., et al. (2009) · Obesity · doi:10.1038/oby.2008.637 · Cited by 525 · see citing works
Four-year weight losses in the Look AHEAD study: factors associated with long-term success
Wadden, T. A., Neiberg, R. H., Wing, R. R., Clark, J. M., Delahanty, L. M., Hill, J. O., Krakoff, J., Otto, A., Ryan, D. H., Vitolins, M. Z., et al. (2011) · Obesity · doi:10.1038/oby.2011.230 · Cited by 465 · see citing works
Diabetes mellitus and Alzheimer's disease: shared pathology and treatment?
Akter, K., Lanza, E. A., Martin, S. A., Myronyuk, N., Rua, M., & Raffa, R. B. (2011) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2010.03830.x · Cited by 352 · see citing works
Sex Differences in the Cardiovascular Consequences of Diabetes Mellitus: A Scientific Statement From the American Heart Association
Regensteiner, J. G., Golden, S., Huebschmann, A. G., Barrett-Connor, E., Chang, A. Y., Chyun, D., Fox, C. S., Kim, C., Mehta, N., Reckelhoff, J. F., et al. (2015) · Circulation · doi:10.1161/cir.0000000000000343 · Cited by 334 · see citing works
Self-citation
Lifestyle change and mobility in obese adults with type 2 diabetes
Rejeski, W. J., Ip, E. H., Bertoni, A. G., Bray, G. A., Evans, G., Gregg, E. W., & Zhang, Q. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1110294 · Cited by 301 · see citing works
Exercise Autonomous Motivation Predicts 3-yr Weight Loss in Women
Silva, M. N., Markland, D. A., Carraça, E. V., Vieira, P. N., Coutinho, S. R., Minderico, C. S., de Matos, M. G., Sardinha, L. B., & Teixeira, P. J. (2010) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181f3818f · Cited by 294 · see citing works
Telephone-Delivered Interventions for Physical Activity and Dietary Behavior Change
Goode, A. D., Reeves, M. M., & Eakin, E. G. (2012) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2011.08.025 · Cited by 253 · see citing works
INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES
Baru, P. C. R. (2014) · ADVANCED SCIENCES INDEX · Cited by 236 · see citing works
The Look AHEAD Trial: a review and discussion of its outcomes
Pi-Sunyer, X. (2014) · Current Nutrition Reports · doi:10.1007/s13668-014-0099-x · Cited by 176 · see citing works
Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: the action for health in diabetes
Espeland, M. A., Glick, H. A., Bertoni, A., Brancati, F. L., Bray, G. A., Clark, J. M., Curtis, J. M., Egan, C., Evans, M., Foreyt, J. P., et al. (2014) · Diabetes Care · doi:10.2337/dc14-0093 · Cited by 174 · see citing works
Self-citation
Exploring equity in primary-care-based physical activity interventions using PROGRESS-Plus: a systematic review and evidence synthesis
Attwood, S., van Sluijs, E. M. F., & Sutton, S. R. (2016) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/s12966-016-0384-8 · Cited by 135 · see citing works
Association of Intensive Lifestyle Intervention, Fitness, and Body Mass Index With Risk of Heart Failure in Overweight or Obese Adults With Type 2 Diabetes Mellitus: An Analysis From the Look AHEAD Trial
Pandey, A., Patel, K. V., Bahnson, J. L., Gaussoin, S. A., Martin, C. K., Balasubramanyam, A., Johnson, K. C., McGuire, D. K., Bertoni, A. G., Kitzman, D., et al. (2020) · Circulation · doi:10.1161/circulationaha.119.044865 · Cited by 127 · see citing works
Self-citation
Cardiovascular Effects of Intensive Lifestyle Intervention in Type 2 Diabetes
Johnston, C. A., Moreno, J. P., & Foreyt, J. P. (2014) · Current Atherosclerosis Reports · doi:10.1007/s11883-014-0457-6 · Cited by 114 · see citing works
Keeping therapies simple: psychoeducation in the prevention of relapse in affective disorders
Colom, F. (2011) · British Journal of Psychiatry · doi:10.1192/bjp.bp.110.090209 · Cited by 99 · see citing works
The Effect of Intentional Weight Loss on Fracture Risk in Persons With Diabetes: Results From the Look AHEAD Randomized Clinical Trial
Johnson, K. C., Bray, G. A., Cheskin, L. J., Clark, J. M., Egan, C. M., Foreyt, J. P., Garcia, K. R., Glasser, S., Greenway, F. L., Gregg, E. W., et al. (2017) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3214 · Cited by 104 · see citing works
Self-citation
A 1-Year Lifestyle Intervention for Weight Loss in Individuals With Type 2 Diabetes Reduces High C-Reactive Protein Levels and Identifies Metabolic Predictors of Change
Belalcazar, L. M., Reboussin, D. M., Haffner, S. M., Hoogeveen, R. C., Kriska, A. M., Schwenke, D. C., Tracy, R. P., Pi-Sunyer, X., & Ballantyne, C. M. (2010) · Diabetes Care · doi:10.2337/dc10-0728 · Cited by 104 · see citing works
Metabolic Changes Following a 1-Year Diet and Exercise Intervention in Patients With Type 2 Diabetes
Albu, J., Heilbronn, L. K., Kelley, D. E., Smith, S. R., Azuma, K., Berk, E. S., Pi-Sunyer, X., & Ravussin, É. (2009) · Diabetes · doi:10.2337/db09-1239 · Cited by 102 · see citing works
Effect of an intensive lifestyle intervention on atrial fibrillation risk in individuals with type 2 diabetes: The Look AHEAD randomized trial
Alonso, Á., Bahnson, J. L., Gaussoin, S. A., Bertoni, A. G., Johnson, K., Lewis, C. E., Vetter, M. L., Mantzoros, C. S., Jeffery, R. W., & Soliman, E. Z. (2015) · American Heart Journal · doi:10.1016/j.ahj.2015.07.026 · Cited by 98 · see citing works
The effects of weight loss after bariatric surgery on health-related quality of life and depression
Strain, G. W., Kolotkin, R. L., Dakin, G. F., Gagner, M., Inabnet, W. B., Christos, P. J., Saif, T., Crosby, R. D., & Pomp, A. (2014) · Nutrition and Diabetes · doi:10.1038/nutd.2014.29 · Cited by 95 · see citing works
Changes in body composition over 8 years in a randomized trial of a lifestyle intervention: The look AHEAD study
Pownall, H. J., Bray, G. A., Wagenknecht, L. E., Walkup, M. P., Heshka, S., Hubbard, V. S., Hill, J., Kahn, S. E., Nathan, D. M., Schwartz, A. V., et al. (2015) · Obesity · doi:10.1002/oby.21005 · Cited by 94 · see citing works
Cardiorespiratory fitness and risk of type 2 diabetes mellitus: A 23-year cohort study and a meta-analysis of prospective studies
Zaccardi, F., O’Donovan, G., Webb, D. R., Yates, T. E., Kurl, S., Khunti, K. K., Davies, M. J., & Laukkanen, J. A. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.09.016 · Cited by 93 · see citing works
Effect of 1 year of an intentional weight loss intervention on bone mineral density in type 2 diabetes: Results from the look AHEAD randomized trial
Schwartz, A. V., Johnson, K., Kahn, S. E., Shepherd, J., Nevitt, M. C., Peters, A. L., Walkup, M. P., Hodges, A., Williams, C. C., & Bray, G. A. (2011) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.1483 · Cited by 90 · see citing works
Does lifestyle intervention improve health of adults with overweight/obesity and type 2 diabetes? Findings from the Look AHEAD randomized trial
Wing, R. R., & the Look AHEAD Research Group (2021) · Obesity · doi:10.1002/oby.23158 · Cited by 88 · see citing works
Light physical activity determined by a motion sensor decreases insulin resistance, improves lipid homeostasis and reduces visceral fat in high-risk subjects: PreDiabEx study RCT
Herzig, K., Ahola, R., Leppäluoto, J., Jokelainen, J. J., Jämsä, T. J., & Keinanen-Kiukaanniemi, S. M. (2013) · International Journal of Obesity · doi:10.1038/ijo.2013.224 · Cited by 84 · see citing works
Overlapped Metabolic and Therapeutic Links between Alzheimer and Diabetes
Ahmad, W. (2012) · Molecular Neurobiology · doi:10.1007/s12035-012-8352-z · Cited by 80 · see citing works
The use of periodization in exercise prescriptions for inactive adults: A systematic review
Strohacker, K., Fazzino, D., Breslin, W. L., & Xu, X. (2015) · Preventive Medicine Reports · doi:10.1016/j.pmedr.2015.04.023 · Cited by 79 · see citing works
Association of Objectively Measured Timing of Physical Activity Bouts With Cardiovascular Health in Type 2 Diabetes
Qian, J., Walkup, M. P., Chen, S., Brubaker, P. H., Bond, D. S., Richey, P. A., Jakicic, J. M., Hu, K., Scheer, F. A. J. L., & Middelbeek, R. J. W. (2021) · Diabetes Care · doi:10.2337/dc20-2178 · Cited by 75 · see citing works
Self-citation
The Look AHEAD Trial: Implications for Lifestyle Intervention in Type 2 Diabetes Mellitus
Dutton, G. R., & Lewis, C. E. (2015) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2015.04.002 · Cited by 75 · see citing works
Intensive weight loss intervention in older individuals: results from the Action for Health in Diabetes Type 2 diabetes mellitus trial
Espeland, M. A., Rejeski, W. J., West, D. S., Bray, G. A., Clark, J. M., Peters, A. L., Chen, H., Johnson, K. C., Horton, E. S., Hazuda, H. P., et al. (2013) · Journal of the American Geriatrics Society · doi:10.1111/jgs.12271 · Cited by 66 · see citing works
Physical Exercise and Its Protective Effects on Diabetic Cardiomyopathy: What Is the Evidence?
Zheng, J., Cheng, J., Zheng, S., Zhang, L., Guo, X., Zhang, J., & Xiao, X. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00729 · Cited by 65 · see citing works
Four-Year Change in Cardiorespiratory Fitness and Influence on Glycemic Control in Adults With Type 2 Diabetes in a Randomized Trial
Jakicic, J. M., Egan, C., Fabricatore, A. N., Gaussoin, S. A., Glasser, S. P., Hesson, L. A., Knowler, W. C., Lang, W., Regensteiner, J. G., Ribisl, P. M., et al. (2012) · Diabetes Care · doi:10.2337/dc12-0712 · Cited by 65 · see citing works
Self-citation
Lifestyle intervention and/or statins for the reduction of C‐reactive protein in type 2 diabetes: From the look AHEAD study
Belalcazar, L. M., Haffner, S. M., Lang, W., Hoogeveen, R. C., Rushing, J., Schwenke, D. C., Tracy, R. P., Pi‐Sunyer, F. X., Kriska, A. M., & Ballantyne, C. M. (2013) · Obesity · doi:10.1002/oby.20431 · Cited by 63 · see citing works
Effect of a long-term intensive lifestyle intervention on cognitive function: Action for Health in Diabetes study
Rapp, S. R., Luchsinger, J. A., Baker, L. D., Blackburn, G. L., Hazuda, H. P., Demos‐McDermott, K. E., Jeffery, R. W., Keller, J. N., McCaffery, J. M., Pajewski, N. M., et al. (2017) · Journal of the American Geriatrics Society · doi:10.1111/jgs.14692 · Cited by 62 · see citing works
Prediabetes: The Importance of Early Identification and Intervention
Hsueh, W. A., Orloski, L., & Wyne, K. L. (2010) · Postgraduate Medicine · doi:10.3810/pgm.2010.07.2180 · Cited by 58 · see citing works
Changes in Adipose Tissue Depots and Metabolic Markers Following a 1-Year Diet and Exercise Intervention in Overweight and Obese Patients With Type 2 Diabetes
Gallagher, D., Heshka, S., Kelley, D. E., Thornton, J., Boxt, L., Pi-Sunyer, F. X., Patricio, J., Mancino, J., Clark, J. M., & the MRI Ancillary Study Group of the Look AHEAD Research Group (2014) · Diabetes Care · doi:10.2337/dc14-1585 · Cited by 59 · see citing works
Physical activity for the prevention and treatment of metabolic disorders
Montesi, L., Moscatiello, S., Malavolti, M., Marzocchi, R., & Marchesini, G. (2013) · Internal and Emergency Medicine · doi:10.1007/s11739-013-0953-7 · Cited by 60 · see citing works
The Look AHEAD Trial: Bone Loss at 4-Year Follow-up in Type 2 Diabetes
Lipkin, E. W., Schwartz, A. V., Anderson, A., Davis, C., Johnson, K., Gregg, E. W., Bray, G. A., Berkowitz, R. I., Peters, A. L., Hodges, A., et al. (2014) · Diabetes Care · doi:10.2337/dc14-0762 · Cited by 56 · see citing works
Four-year physical activity levels among intervention participants with type 2 diabetes
UNICK, J. L., GAUSSOIN, S. A., HILL, J. O., JAKICIC, J. M., BOND, D. S., HELLGREN, M., JOHNSON, K. C., PETERS, A. L., CODAY, M., KITZMAN, D. W., et al. (2016) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001054 · Cited by 52 · see citing works
Self-citation
Changes in skeletal muscle and organ size after a weight-loss intervention in overweight and obese type 2 diabetic patients
Gallagher, D., Kelley, D. E., Thornton, J., Boxt, L., Pi-Sunyer, X., Lipkin, E., Nyenwe, E., Janumala, I., & Heshka, S. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.139188 · Cited by 50 · see citing works
Molecular and biochemical trajectories from diabetes to Alzheimer’s disease: A critical appraisal
Sandhir, R., & Gupta, S. N. (2015) · World Journal of Diabetes · doi:10.4239/wjd.v6.i12.1223 · Cited by 47 · see citing works
Effect of improved fitness beyond weight loss on cardiovascular risk factors in individuals with type 2 diabetes in the Look AHEAD study
Gibbs, B. B., Brancati, F. L., Chen, H., Coday, M., Jakicic, J. M., Lewis, C. E., Stewart, K. J., & Clark, J. M. (2012) · European Journal of Preventive Cardiology · doi:10.1177/2047487312462823 · Cited by 48 · see citing works
Self-citation
Navigating the intersection: Diabetes and Alzheimer's intertwined relationship
Kale, M. B., Bhondge, H. M., Wankhede, N. L., Shende, P. V., Thanekar, R., Aglawe, M. M., Rahangdale, S. R., Taksande, B. G., Pandit, S. B., Upaganlawar, A. B., et al. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102415 · Cited by 38 · see citing works
The Role of Lifestyle Change in the Prevention and Treatment of NAFLD
Centis, E., Marzocchi, R., Suppini, A., Grave, R., Villanova, N., Hickman, I. J., & Marchesini, G. (2013) · Current Pharmaceutical Design · doi:10.2174/1381612811319290008 · Cited by 38 · see citing works
Weight Loss and Physical Activity for Disease Prevention in Obese Older Adults: an Important Role for Lifestyle Management
Valencia, W. M., Stoutenberg, M., & Florez, H. (2014) · Current Diabetes Reports · doi:10.1007/s11892-014-0539-4 · Cited by 37 · see citing works
Improving Adiponectin Levels in Individuals With Diabetes and Obesity: Insights From Look AHEAD
Belalcazar, L. M., Lang, W., Haffner, S. M., Schwenke, D. C., Kriska, A. M., Balasubramanyam, A., Hoogeveen, R. C., Pi‐Sunyer, F. X., Tracy, R. P., & Ballantyne, C. M. (2015) · Diabetes Care · doi:10.2337/dc14-2775 · Cited by 34 · see citing works
Self-citation
Genetic Modifiers of Cardiorespiratory Fitness Response to Lifestyle Intervention
Peter, I., Papandonatos, G. D., Belalcazar, L. M., Yang, Y., Erar, B., Jakicic, J. M., Unick, J. L., Balasubramanyam, A., Lipkin, E. W., Delahanty, L. M., et al. (2013) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3182a66155 · Cited by 34 · see citing works
Self-citation
Type 2 diabetes exaggerates exercise effort and impairs exercise performance in older women
Huebschmann, A. G., Kohrt, W. M., Herlache, L., Wolfe, P., Daugherty, S. L., Reusch, J. E. B., Bauer, T. A., & Regensteiner, J. G. (2015) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2015-000124 · Cited by 33 · see citing works
Self-citation
Correlates of Heart Rate Measures with Incidental Physical Activity and Cardiorespiratory Fitness in Overweight Female Workers
Tonello, L., Reichert, F. F., Silva, I. O., Rosso, S. D., Leicht, A. S., & Boullosa, D. A. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2015.00405 · Cited by 32 · see citing works
Exercise and Diabetes-Related Cardiovascular Disease: Systematic Review of Published Evidence from Observational Studies and Clinical Trials
Koivula, R. W., Tornberg, Å. B., & Franks, P. W. (2013) · Current Diabetes Reports · doi:10.1007/s11892-013-0373-0 · Cited by 31 · see citing works
Liraglutide Does Not Adversely Impact Fat‐Free Mass Loss
Grannell, A., Martin, W. P., Dehestani, B., Al‐Najim, W., Murphy, J. C., & le Roux, C. W. (2021) · Obesity · doi:10.1002/oby.23098 · Cited by 29 · see citing works
Lifestyle Intervention Improves Heart Rate Recovery from Exercise in Adults with Type 2 Diabetes: Results from the Look AHEAD Study
Ribisl, P. M., Gaussoin, S. A., Lang, W., Bahnson, J. L., Connelly, S. A., Horton, E. S., Jakicic, J. M., Killean, T., Kitzman, D. W., Knowler, W. C., et al. (2012) · Journal of Obesity · doi:10.1155/2012/309196 · Cited by 29 · see citing works
Self-citation
Cardiovascular responses to physical activity during work and leisure
Quinn, T. D., Kline, C. E., Nagle, E. F., Radonovich, L. J., Alansare, A. B., & Gibbs, B. B. (2021) · Occupational and Environmental Medicine · doi:10.1136/oemed-2021-107551 · Cited by 29 · see citing works
Examining behavioral processes through which lifestyle interventions promote weight loss: Results from PREMIER
Fitzpatrick, S. L., Bandeen‐Roche, K., Stevens, V. J., Coughlin, J. W., Rubin, R. R., Brantley, P. J., Funk, K., Svetkey, L. P., Jerome, G. J., Dalcin, A., et al. (2013) · Obesity · doi:10.1002/oby.20636 · Cited by 26 · see citing works
Association Between Physical Exercise Interventions Participation and Functional Capacity in Individuals with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Controlled Trials
Pfeifer, L. O., Nardi, A. T. D., da Silva, L. X. N., Botton, C. E., do Nascimento, D. M., Teodoro, J. L., Schaan, B. D., & Umpierre, D. (2022) · Sports Medicine - Open · doi:10.1186/s40798-022-00422-1 · Cited by 25 · see citing works
The Effect of Changes in Cardiorespiratory Fitness and Weight on Obstructive Sleep Apnea Severity in Overweight Adults with Type 2 Diabetes
Kline, C. E., Reboussin, D. M., Foster, G. D., Rice, T. B., Strotmeyer, E. S., Jakicic, J. M., Millman, R. P., Pi-Sunyer, F. X., Newman, A. B., Wadden, T. A., et al. (2016) · Sleep · doi:10.5665/sleep.5436 · Cited by 24 · see citing works
Self-citation
A steep ramp test is valid for estimating maximal power and oxygen uptake during a standard ramp test in type 2 diabetes
Rozenberg, R., Bussmann, J. B. J., Lesaffre, E., Stam, H. J., & Praet, S. (2014) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.12357 · Cited by 21 · see citing works
Long-term Impact of a 10-Year Intensive Lifestyle Intervention on a Deficit Accumulation Frailty Index: Action for Health in Diabetes Trial
Evans, J. K., Usoh, C. O., Simpson, F. R., Espinoza, S. E., Hazuda, H. P., Pandey, A., Beckner, T., & Espeland, M. A. (2023) · The Journals of Gerontology Series A · doi:10.1093/gerona/glad088 · Cited by 19 · see citing works
Impact of intensive lifestyle intervention on preference‐based quality of life in type 2 diabetes: Results from the L ook AHEAD trial
Zhang, P., Hire, D. G., Espeland, M. A., Knowler, W. C., Thomas, S., Tsai, A. G., & Glick, H. A. (2016) · Obesity · doi:10.1002/oby.21445 · Cited by 19 · see citing works
Effects of Longitudinal Glucose Exposure on Cognitive and Physical Function: Results from the Action for Health in Diabetes Movement and Memory Study
Beavers, K. M., Leng, I., Rapp, S. R., Miller, M. E., Houston, D. K., Marsh, A. P., Hire, D. G., Baker, L. D., Bray, G. A., Blackburn, G. L., et al. (2016) · Journal of the American Geriatrics Society · doi:10.1111/jgs.14478 · Cited by 19 · see citing works
Self-citation
Does the Impact of Intensive Lifestyle Intervention on Cardiovascular Disease Risk Vary According to Frailty as Measured via Deficit Accumulation?
Simpson, F. R., Pajewski, N. M., Beavers, K. M., Kritchevsky, S. B., McCaffery, J. M., Nicklas, B. J., Wing, R. R., Bertoni, A. G., Ingram, F., Ojeranti, D., et al. (2020) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaa153 · Cited by 19 · see citing works
Criterion validity and reliability of a smartphone delivered sub-maximal fitness test for people with type 2 diabetes
Brinkløv, C. F., Thorsen, I. K., Karstoft, K., Brøns, C., Valentiner, L. S., Langberg, H., Vaag, A. A., Nielsen, J. S., Pedersen, B. K., & Ried‐Larsen, M. (2016) · BMC Sports Science Medicine and Rehabilitation · doi:10.1186/s13102-016-0056-7 · Cited by 18 · see citing works
Cardiorespiratory Fitness Levels and its Correlates Among Adults with Diabetes
Loprinzi, P. D., & Pariser, G. L. (2013) · Cardiopulmonary Physical Therapy Journal · doi:10.1097/01823246-201324020-00005 · Cited by 19 · see citing works
Cardiorespiratory fitness, BMI, mortality, and cardiovascular disease in adults with overweight/obesity and type 2 diabetes
WILLS, A. C., VAZQUEZ ARREOLA, E., OLAIYA, M. T., CURTIS, J. M., HELLGREN, M. I., HANSON, R. L., & KNOWLER, W. C. (2022) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002873 · Cited by 18 · see citing works
Self-citation
Vitamin D Deficiency is a Surrogate Marker for Visceral Fat Content, Metabolic Syndrome, Type 2 Diabetes, and Future Metabolic Complications
Wimalawansa, S. J. (2016) · Journal of Diabetes Metabolic Disorders & Control · doi:10.15406/jdmdc.2016.03.00059 · Cited by 18 · see citing works
(−)-Epicatechin-3-O-β-d-allopyranoside from Davallia formosana, Prevents Diabetes and Hyperlipidemia by Regulation of Glucose Transporter 4 and AMP-Activated Protein Kinase Phosphorylation in High-Fat-Fed Mice
Shih, C., Wu, J., Jian, J.-Y., Lin, C., & Ho, H. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms161024983 · Cited by 17 · see citing works
Exercise and Stevia Rebaudiana (R) Extracts Attenuate Diabetic Cardiomyopathy in Type 2 Diabetic Rats: Possible Underlying Mechanisms
Hussein, A. M., Eid, E. A., Bin‐Jaliah, I., Taha, M., & Lashin, L. S. (2020) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530320666200420084444 · Cited by 17 · see citing works
Maintenance of improvements in fitness and fatness 1 year after a 3-month lifestyle intervention in overweight men
Rosenkilde, M., Nordby, P., & Stallknecht, B. (2016) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2016.64 · Cited by 15 · see citing works
The long-term effect of intentional weight loss on changes in bone mineral density in persons with type 2 diabetes: results from the Look AHEAD randomized trial
Johnson, K., Anderson, A., Beavers, K. M., Crandall, C. J., Hazuda, H. P., Lewis, C. E., Lipkin, E. W., Schwartz, A. V., Pi-Sunyer, X., & Zhao, Q. (2023) · Archives of Osteoporosis · doi:10.1007/s11657-023-01303-0 · Cited by 15 · see citing works
Correlates of cardiorespiratory fitness among overweight or obese individuals with type 2 diabetes
Kazé, A. D., Agoons, D. D., Santhanam, P., Erqou, S. A., Ahima, R. S., & Echouffo-Tcheugui, J. B. (2022) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2021-002446 · Cited by 15 · see citing works
Baseline predictors of missed visits in the look AHEAD study
Fitzpatrick, S. L., Jeffery, R. W., Johnson, K., Roche, C. C., Dorsten, B. V., Gee, M., Johnson, R. A., Charleston, J. B., Dotson, K., Walkup, M. P., et al. (2013) · Obesity · doi:10.1002/oby.20613 · Cited by 15 · see citing works
Role of physical activity in obesity treatment and cardiometabolic health: a scientific statement from the American Heart Association
Swift, D. L., Ross, L. M., Laddu, D. R., Conroy, M. B., German, C. A., Evangelista, L. S., Marvel, F. A., Jerome, G. J., on behalf the American Heart Association Council on Lifestyle and Cardiometabolic Health, Council on Cardiovascular and Stroke Nursing, et al. (2026) · Circulation · doi:10.1161/cir.0000000000001441 · Cited by 13 · see citing works
Efficacy of a Computerized Simulation in Promoting Walking in Individuals With Diabetes
Gibson, B., Marcus, R. L., Staggers, N., Jones, J., Samore, M. H., & Weir, C. R. (2012) · Journal of Medical Internet Research · doi:10.2196/jmir.1965 · Cited by 12 · see citing works
Divide and Conquer: The Multidisciplinary Approach to Achieving Significant Long-Term Weight Loss and Improved Glycemic Control in Obese Patients With Type 2 Diabetes
Bishay, R. H., Omari, A., Zang, J., Lih, A., & Kormas, N. (2013) · Clinical Diabetes · doi:10.2337/diaclin.31.1.14 · Cited by 12 · see citing works
Opportunities for Intervention Strategies for Weight Management: Global Actions on Fluid Intake Patterns
Lafontan, M., Visscher, T. L. S., Farpour‐Lambert, N. J., & Yumuk, V. (2015) · Obesity Facts · doi:10.1159/000375103 · Cited by 12 · see citing works
A common variant in the CLDN7/ELP5 locus predicts adiponectin change with lifestyle intervention and improved fitness in obese individuals with diabetes
Belalcazar, L. M., Papandonatos, G. D., McCaffery, J. M., Peter, I., Pajewski, N. M., Erar, B., Palmer, N. D., Balasubramanyam, A., Bowden, D. W., Brautbar, A., et al. (2015) · Physiological Genomics · doi:10.1152/physiolgenomics.00109.2014 · Cited by 11 · see citing works
Self-citation
Longitudinal association between body mass index and physical activity among adolescents with different parental risk: a parallel latent growth curve modeling approach
Naseri, P., Amiri, P., Momenyan, S., Zayeri, F., Karimi, M., & Azizi, F. (2020) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/s12966-020-00961-4 · Cited by 11 · see citing works
Effect of Obesogenic Medication on Weight‐ and Fitness‐Change Outcomes: Evidence from the Look AHEAD Study
Moon, R. C., & Almuwaqqat, Z. (2020) · Obesity · doi:10.1002/oby.22997 · Cited by 9 · see citing works
Self-Reported Gastrointestinal Symptoms in Type 2 Diabetes Improve With an Intensive Lifestyle Intervention: Results From the Action for Health in Diabetes (Look AHEAD) Clinical Trial
Neiberg, R. H., Rejeski, J., Applegate, W. B., Clark, J. M., Knowler, W. C., Bray, G. A., Espeland, M. A., & Cheskin, L. J. (2015) · Clinical Diabetes · doi:10.2337/diaclin.33.4.181 · Cited by 10 · see citing works
History of Cardiovascular Disease, Intensive Lifestyle Intervention, and Cardiovascular Outcomes in the Look AHEAD Trial
Lewis, C. E., Bantle, J. P., Bertoni, A. G., Blackburn, G. L., Brancati, F. L., Bray, G. A., Cheskin, L. J., Curtis, J. M., Egan, C., Evans, M. E., et al. (2020) · Obesity · doi:10.1002/oby.22676 · Cited by 9 · see citing works
Self-citation
Physical Activity in the Workplace: Does Just Working Meet Activity Recommendations?
Quinn, T. D., Kline, C. E., Nagle, E. F., Radonovich, L. J., & Gibbs, B. B. (2021) · Workplace Health & Safety · doi:10.1177/21650799211055174 · Cited by 9 · see citing works
The results of Look AHEAD do not row against the implementation of lifestyle changes in patients with type 2 diabetes
Annuzzi, G., Rivellese, A. A., Bozzetto, L., & Riccardi, G. (2013) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2013.12.001 · Cited by 9 · see citing works
Associations that Cardiorespiratory Fitness and Body Mass Index Loss Have with Deficit Accumulation Frailty
Olson, K. L., Houston, D. K., Ross, J., Wing, R. R., Simpson, F. R., Pandey, A., Walkup, M. P., Yang, M., & Espeland, M. A. (2023) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000003353 · Cited by 8 · see citing works
Applying the Behavior Change Technique Taxonomy from Public Health Interventions to Educational Research
Cho, J. Y., & Kizilcec, R. F. (2021) · ACM Conference on Learning @ Scale (L@S) · doi:10.1145/3430895.3460138 · Cited by 8 · see citing works
Association Between Microvascular Disease and Cardiorespiratory Fitness Among Adults With Type 2 Diabetes
Kazé, A. D., Santhanam, P., Ahima, R. S., Bertoni, A. G., & Echouffo-Tcheugui, J. B. (2024) · Diabetes Care · doi:10.2337/dc24-0294 · Cited by 8 · see citing works
Diabetic Foot Ulcer Beyond Wound Closure: Clinical Practice Guideline
Wendland, D. M., Altenburger, E. A., Swen, S. B., & Haan, J. (2024) · Physical Therapy · doi:10.1093/ptj/pzae171 · Cited by 8 · see citing works
Long-Term Effects of an Intensive Lifestyle Intervention on Electrocardiographic Criteria for Left Ventricular Hypertrophy: The Look AHEAD Trial
Brinkley, T. E., Anderson, A., Soliman, E. Z., Bertoni, A. G., Greenway, F. L., Knowler, W. C., Glasser, S. P., Horton, E. S., & Espeland, M. A. (2018) · American Journal of Hypertension · doi:10.1093/ajh/hpy004 · Cited by 8 · see citing works
An Interactive Simulation to Change Outcome Expectancies and Intentions in Adults With Type 2 Diabetes: Within-Subjects Experiment
Gibson, B., Yingling, L., Bednarchuk, A., Janamatti, A., Oakley-Girvan, I. A., & Allen, N. A. (2018) · JMIR Diabetes · doi:10.2196/diabetes.8069 · Cited by 8 · see citing works
Physical Activity, Cardiorespiratory Fitness, and the Diabetes Spectrum
Nylen, E. S., & Kokkinos, P. F. (2019) · Springer eBooks · doi:10.1007/978-3-030-04816-7_11 · Cited by 8 · see citing works
Relative differences in resting-state brain connectivity associated with long term intensive lifestyle intervention
Casanova, R., Hayasaka, S., Saldana, S. J., Bryan, R. N., Demos, K. E., Desiderio, L. M., Erickson, K. I., Espeland, M. A., Nasrallah, I. M., Wadden, T. A., et al. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.09.016 · Cited by 7 · see citing works
Age, Race, Sex and Cardiorespiratory Fitness: Implications for Prevention and Management of Cardiometabolic Disease in Individuals with Diabetes Mellitus
Nylén, E. (2024) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2507263 · Cited by 7 · see citing works
Impact of weight loss on ankle‐brachial index and interartery blood pressures
Espeland, M. A., Lewis, C. E., Bahnson, J. L., Knowler, W. C., Regensteiner, J. G., Gaussoin, S. A., Beavers, D. P., & Johnson, K. (2013) · Obesity · doi:10.1002/oby.20658 · Cited by 7 · see citing works
Self-citation
Metabolic Surgery Is No Longer Just Bariatric Surgery
Moore, E. C., & Pories, W. J. (2014) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2014.1509 · Cited by 7 · see citing works
Constructing common cohorts from trials with overlapping eligibility criteria: implications for comparing effect sizes between trials
Mount, D. L., Feeney, P. A., Fabricatore, A. N., Coday, M., Bahnson, J. L., Byington, R. P., Phelan, S., Wilmoth, S. K., Knowler, W. C., HRAMIAK, I. M., et al. (2009) · Clinical Trials · doi:10.1177/1740774509344440 · Cited by 7 · see citing works
Validity of Ratings of Perceived Exertion in Patients with Type 2 Diabetes
Unick, J. L. (2014) · Journal of Novel Physiotherapy and Physical Rehabilitation · doi:10.17352/2455-5487.000002 · Cited by 7 · see citing works

AHEAD Study
Jakicic, J. M., Ph. D. [writing Group Chair, & Jaramillo, S. A. (2016)
Self-citation
Four-Year Change in Cardiorespiratory Fitness and Influence on Glycemic Control in Adults With Type 2 Diabetes in a Randomized Trial
Jakicic, J. M., Egan, C., Fabricatore, A. N., Gaussoin, S. A., Glasser, S. P., Hesson, L. A., Knowler, W. C., Lang, W., Regensteiner, J. G., Ribisl, P. M., et al. (2012) · Diabetes Care · doi:10.2337/dc12-0712 · Cited by 65 · see citing works
Self-citation
Effect of improved fitness beyond weight loss on cardiovascular risk factors in individuals with type 2 diabetes in the Look AHEAD study
Gibbs, B. B., Brancati, F. L., Chen, H., Coday, M., Jakicic, J. M., Lewis, C. E., Stewart, K. J., & Clark, J. M. (2012) · European Journal of Preventive Cardiology · doi:10.1177/2047487312462823 · Cited by 48 · see citing works
Self-citation
Effectiveness of Lifestyle Interventions for IndividualsWith Severe Obesity and Type 2 Diabetes Results from the Look AHEAD trial
Unick, J. L., Phd, D. B., Jakicic, J. M., Kitabchi, A. E., Knowler, W. C., Wadden, T. A., & Wing, R. R. (2016)
Self-citation
Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the Look AHEAD randomised clinical trial
(2016) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(16)30162-0 · Cited by 738 · see citing works
Self-citation

Authors: Look AHEAD Study Group, Jakicic, J. M., Jaramillo, S. A., Balasubramanyam, A., Bancroft, B., Curtis, J. M., Mathews, A., Pereira, M., Regensteiner, J. G., & Ribisl, P. M.
Affiliations: University of Pittsburgh (US)
Corresponding author: Jakicic, J M
ORCID: Mathews, A
Pereira, M
Regensteiner, J G
Venue: International Journal of Obesity
Publisher: Springer Science and Business Media LLC
Published: 2009-01-20
Volume: 33
Issue: 3
Pages: 305-316
ISSN: 0307-0565 (ISSN-L)
1476-5497
DOI: 10.1038/ijo.2008.280
PMC: PMC2656590
OpenAlex: W2042461436
Semantic Scholar: 6b97bf43f04dbaf4e6bef854fd4b17b8b7f0c4dd
Cited by: 145
References: 24
Citations by year: 2026: 3 · 2025: 4 · 2024: 8 · 2023: 3 · 2022: 5 · 2021: 8 · 2020: 8 · 2019: 2 · 2018: 5 · 2017: 7 · 2016: 14 · 2015: 19 · 2014: 13 · 2013: 15 · 2012: 13
FWCI: 6.77
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.springer.com/tdm (tdm)
Locations: International Journal of Obesity (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: U.S. Department of Health and Human Services
Johns Hopkins University
National Institutes of Health (UL1TR000005, 5p30dk046204-15)
National Institute of Diabetes and Digestive and Kidney Diseases (DK-57171, DK 57136, DK57149, DK57182, DK56990, (DK 046204, DK57008, DK57177, DK 57078, DK57219, U01DK057149, DK-57178, U01DK057151, U01DK057135, U01DK057131, U01DK056990, DK-57135, U01DK057136, DK-56992, DK57154, U01DK057178, U01DK057182, U01DK057078, U01DK057154, U01DK057008, U01DK057171, DK57131, U01DK057219, U01DK056992, U01DK057177, P30DK048520, DK 57151)
National Center for Research Resources (M01-RR-0021140, M01RR002719, M01RR000056, M01RR000051, M01RR001066, M01RR001346)
National Center for Advancing Translational Sciences
Topics: Health Sciences › Medicine › Physiology › Physical Activity and Health
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Keywords: type 2 diabetes, cardiorespiratory fitness, lifestyle intervention, weight loss, physical activity, diabetes support and education, Look AHEAD trial, obesity, overweight, caloric restriction, metabolic control
MeSH terms: Cardiovascular Diseases, Diabetes Mellitus, Type 2, Diabetic Angiopathies, Exercise Test, Female, Humans, Life Style, Male, Middle Aged, Obesity, Physical Fitness, Surveys and Questionnaires, Weight Loss, Exercise, Multivariate Analysis, Risk Reduction Behavior

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Effect of a lifestyle intervention on change in cardiorespiratory fitness in adults with type 2 diabetes: results from the Look AHEAD Study

Abstract

Integrity signals

Claims the paper makes

Self-check

Cites

Cited by

Related

Record

About these checks