The DOI matches its Crossref record; 28 of the 31 references it cites were found in a registry or an index; none of the 19 sources its claims cite is checked for support yet.
The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions
Open accessAbstract
The Global Burden of Disease (GBD) Study 2010 estimated the GBD attributable to 15 categories of skin disease from 1990 to 2010 for 187 countries. For each of the following diseases, we performed systematic literature reviews and analyzed resulting data: eczema, psoriasis, acne vulgaris, pruritus, alopecia areata, decubitus ulcer, urticaria, scabies, fungal skin diseases, impetigo, abscess, and other bacterial skin diseases, cellulitis, viral warts, molluscum contagiosum, and non-melanoma skin cancer. We used disability estimates to determine nonfatal burden. Three skin conditions, fungal skin diseases, other skin and subcutaneous diseases, and acne were in the top 10 most prevalent diseases worldwide in 2010, and eight fell into the top 50; these additional five skin problems were pruritus, eczema, impetigo, scabies, and molluscum contagiosum. Collectively, skin conditions ranged from the 2nd to 11th leading cause of years lived with disability at the country level. At the global level, skin conditions were the fourth leading cause of nonfatal disease burden. Using more data than has been used previously, the burden due to these diseases is enormous in both high- and low-income countries. These results argue strongly to include skin disease prevention and treatment in future global health strategies as a matter of urgency.
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The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“However, the high burden of disability related to eczema remains consistent globally.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > DISCUSSION
Strength:plain· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesA result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Collectively, skin conditions ranged from being the 2nd to 11th leading cause of years lived with disability at the country level for 2010; they range from 3rd to 28th, taking into account premature deaths.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Disability due to skin disease
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In the paper
“In Oceania, sub-Saharan Africa, southeast Asia, and the tropical Americas, skin infections assume a higher proportion of the disease burden (Leekassa et al., 2005;Steer et al., 2009).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > DISCUSSION
What the sources say
- Not checked yetcites Leekassa et al., 2005
- Not checked yetcites Steer et al., 2009 source
Strength:plain· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesA result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Singapore, Brunei, Hungary, and Sudan experienced the most nonfatal skin disease burden per capita in both 1990 and 2010, and Albania, Lithuania, Romania, and Indonesia the least.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Disability due to skin disease
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesA result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Singapore, Brunei, Hungary, and Sudan experienced the most nonfatal skin disease burden per capita in both 1990 and 2010, and Albania, Lithuania, Romania, and Indonesia the least.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Disability due to skin disease
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesThe paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Across specific causes, ages, and regions, burden is higher among females.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Disability due to skin disease
Strength:plain· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesA result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Collectively, skin conditions were the 4th leading cause of nonfatal burden expressed as years lost due to disability in 2010; taking into account health loss due to premature death expressed as disability-adjusted life years (DALYs), skin remains the 18th leading cause of health burden worldwide (Tables 1 and 2).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > RESULTS
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesThe paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“The leading cause of skin condition DALYs is eczema, when looking across countries, ages, sex, and time because of the combined high prevalence across geographies and population and relatively high average disability weight.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Disability due to skin disease
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIn the paper
“Three skin conditions were in the top 10 most prevalent diseases globally in 2010-fungal skin diseases (4th global prevalence ¼ 984,290,432), other skin and subcutaneous diseases (5th), and acne vulgaris (8th global prevalence ¼ 645,499,136; Vos et al., 2012).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Key prevalence findings
What the sources say
- Not checked yetcites Vos et al., 2012 source
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesA result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Three skin conditions, fungal skin diseases, other skin and subcutaneous diseases, and acne were in the top 10 most prevalent diseases worldwide in 2010, and eight fell into the top 50; these additional five skin problems were pruritus, eczema, impetigo, scabies, and molluscum contagiosum.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Abstract
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- It may state two separate claims as one. 24
- Probably not a substantial claim. 21
In the paper
“Three skin conditions were in the top 10 most prevalent diseases globally in 2010-fungal skin diseases (4th global prevalence ¼ 984,290,432), other skin and subcutaneous diseases (5th), and acne vulgaris (8th global prevalence ¼ 645,499,136; Vos et al., 2012).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Key prevalence findings
What the sources say
- Not checked yetcites Vos et al., 2012 source
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“There are further five skin diseases in the top 50 most common causes of diseasepruritus (global prevalence ¼ 279,889,120), eczema (global prevalence ¼ 229,761,000), impetigo (global prevalence ¼ 140,495,000), molluscum contagiosum/warts (global prevalence ¼ 122,601,000), and scabies (global prevalence ¼ 100,625,000).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Key prevalence findings
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“There is also a high burden of skin disease in the elderly above the age of 70 years, where eczema, ulceration, other skin conditions, NMSC, infections, and pruritus are key problems.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > DISCUSSION
Strength:plain· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Rates differ substantially by cause across regions: western Europe has the highest prevalence rate for pruritus but the lowest for scabies and eastern sub-Saharan Africa has the highest rates of cellulitis, fungal skin disease, and viral warts but the lowest rates of urticaria.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Disability due to skin disease
Strength:plain· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“By age 1 year, skin problems already assume importance as a reason for disability with high levels seen in teenage years.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > DISCUSSION
Strength:plain· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“There are further five skin diseases in the top 50 most common causes of diseasepruritus (global prevalence ¼ 279,889,120), eczema (global prevalence ¼ 229,761,000), impetigo (global prevalence ¼ 140,495,000), molluscum contagiosum/warts (global prevalence ¼ 122,601,000), and scabies (global prevalence ¼ 100,625,000).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Key prevalence findings
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“There are further five skin diseases in the top 50 most common causes of diseasepruritus (global prevalence ¼ 279,889,120), eczema (global prevalence ¼ 229,761,000), impetigo (global prevalence ¼ 140,495,000), molluscum contagiosum/warts (global prevalence ¼ 122,601,000), and scabies (global prevalence ¼ 100,625,000).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Key prevalence findings
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“Three skin conditions were in the top 10 most prevalent diseases globally in 2010-fungal skin diseases (4th global prevalence ¼ 984,290,432), other skin and subcutaneous diseases (5th), and acne vulgaris (8th global prevalence ¼ 645,499,136; Vos et al., 2012).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Key prevalence findings
What the sources say
- Not checked yetcites Vos et al., 2012 source
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“There are further five skin diseases in the top 50 most common causes of diseasepruritus (global prevalence ¼ 279,889,120), eczema (global prevalence ¼ 229,761,000), impetigo (global prevalence ¼ 140,495,000), molluscum contagiosum/warts (global prevalence ¼ 122,601,000), and scabies (global prevalence ¼ 100,625,000).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Key prevalence findings
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“There are further five skin diseases in the top 50 most common causes of diseasepruritus (global prevalence ¼ 279,889,120), eczema (global prevalence ¼ 229,761,000), impetigo (global prevalence ¼ 140,495,000), molluscum contagiosum/warts (global prevalence ¼ 122,601,000), and scabies (global prevalence ¼ 100,625,000).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Key prevalence findings
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“To ensure uniformity of investigational approach, training was provided by the Institute of Health Metrics, and participants used a common procedure manual.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > MATERIALS AND METHODS
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The inclusion criteria were studies that were published between 1980 and 2010 that provided data on relevant disease incidence or prevalence.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Search strategy for identification of studies
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim. It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“It pervades all cultures, occurs at all ages, and affects between 30% and 70% of individuals, with even higher rates in at-risk subpopulations (NHANES, 1978;Bickers et al., 2006;Scholfield et al., 2009;Hay and Fuller, 2012).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > INTRODUCTION
What the sources say
- Not checked yetcites NHANES, 1978
- Not checked yetcites Bickers et al., 2006 source
- Not checked yetcites Scholfield et al., 2009
Strength:plain· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Data were analyzed using a Baysian meta-regression tool, described below, to harmonize discordant data where multiple estimates were available as well as fill in gaps in geography, time, or age-sex groups, where data were lacking.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > MATERIALS AND METHODS
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
In the paper
“Disability was derived from an analysis of the comparative impact of the direct disabling consequences of skin disease such as itch and disfigurement against other conditions through a disability weights survey, which involved the use of international panels of volunteers, a telephone-based survey, and a web-based tool.Consistency was demonstrated among all six sources (Salomon et al., 2012).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Disability
What the sources say
- Not checked yetcites Salomon et al., 2012 source
Load-bearingStrength:boosted· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“In terms of age ranges, design of surveys, and even case definitions, data sources did not follow a uniform approach.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > DISCUSSION
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What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Both measures are applied to whole populations without differentiating for potential variables such as social class or environment.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Disability
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“Social factors such as poverty, affluence, inequality, education, and access to health care all have an important role in the epidemiology of skin disease (NHANES, 1978;Williams et al., 1994;Gibbs, 1996;Figueroa et al., 1998;Scholfield et al., 2009).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Analysis of data
What the sources say
- Not checked yetcites NHANES, 1978
- Not checked yetcites Williams et al., 1994
- Not checked yetcites Gibbs, 1996 source
Strength:plain· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Skin diseases of similar severities and extents will affect different subject's lives in strikingly different ways, but for consistency and because of data limitations, the disability weights were defined as such.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Disability
Strength:plain· not yet calibratedCausal:direct· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The study group also found, as anticipated, that there were substantial areas of missing and variable quality data at the regional level.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > DISCUSSION
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What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The GBD 2010 Skin Conditions Expert Group provided the lead in data collection and disease consultation for all analyses.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > MATERIALS AND METHODS
Strength:plain· not yet calibratedCausal:direct· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Studies were excluded for the following reasons: Data in study were self-reported unless it had been validated by the diagnosis of a trained physician”
- Also stated in: § Search strategy for identification of studies · plain
“Sample size smaller than 100 Experimental arm of a clinical trial Papers that provided estimates rather than data”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Search strategy for identification of studies
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim. It may state two separate claims as one.
- Also stated in: § Search strategy for identification of studies · plain
In the paper
“Children and their families often bear the brunt of this disease burden (Mahe, 2005).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > INTRODUCTION
What the sources say
- Not checked yetcites Mahe, 2005
Strength:plain· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The reviews were carried out in three stages: Round (1): Title/abstract review of hits from searches of medical literature databases.”
- Also stated in: § Search strategy for identification of studies · plain
“Round (2): Whole article review of hits remaining after Round 1. Round (3): Evaluation of articles remaining after Round 2 using agreed quality criteria.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Search strategy for identification of studies
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
- Also stated in: § Search strategy for identification of studies · plain
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Data were collected in a two stage literature review.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Search strategy for identification of studies
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Ultimately, 895 country-years of data were used, covering 82 countries.Individual cause models used from 16 to 155 country-years worth of data.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Search strategy for identification of studies
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In the paper
“Previously reported GBD estimated annual deaths for skin disease included 66.5 Â 10 3 from bacterial skin infections such as cellulitis and 30.6 Â 10 3 from NMSC (Lozano et al., 2012).”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Key prevalence findings
What the sources say
- Not checked yetcites Lozano et al., 2012 source
Strength:hedged· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“Standardized disease definitions were established in several ways.For instance, with atopic dermatitis, within the broader heading of eczema, definitions such as the UK working party definition of AD were used (Williams et al., 1994).Likewise in NMSC histopathological confirmation was required.Elsewhere, the diagnosis of a trained health worker was the standard case definition.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > MATERIALS AND METHODS
What the sources say
- Not checked yetcites Williams et al., 1994
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The classification of skin disease was derived from International Classification of Disease 10, which led to the inclusion of most diseases seen in dermatology clinics under skin, but other skin problems under other medical specialities.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > DISCUSSION
Strength:plain· not yet calibratedCausal:direct· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“However, this can now be contextualized with all other disease to show that skin conditions are both widespread and among the most prevalent and disabling diseases, and a source of considerable loss of healthy life.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > DISCUSSION
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The lower burden due to skin infection in the high-income Asian region highlights the impact of poverty in addition to climate in defining risk.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > DISCUSSION
Strength:plain· not yet calibratedCausal:direct· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“For each of the following diseases, we performed systematic literature reviews and analyzed resulting data: eczema, psoriasis, acne vulgaris, pruritus, alopecia areata, decubitus ulcer, urticaria, scabies, fungal skin diseases, impetigo, abscess, and other bacterial skin diseases, cellulitis, viral warts, molluscum contagiosum, and non-melanoma skin cancer.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > Abstract
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Therefore, the impact of skin diseases must be viewed in terms of local health needs, as regional variations in disability may reflect differences in both prevalence and availability of health care.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > DISCUSSION
Tests✓ Asserted: passes✗ Checkable: fails✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim. It may be too vague to check against evidence. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The team reviewed world literature and databases for incidence, prevalence, and remission rates, using acceptable case definitions and stringent criteria for validity of data collection.”
§ The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions > MATERIALS AND METHODS
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim. It may state two separate claims as one.
The paper relies on this without support.
Skin disease receives comparatively little attention in national and global health policy discussions.
“Yet despite this profound impact, skin disease continues to receive relatively little attention in the national or global health debate.”
The paper relies on this without support.
A few skin conditions account for most of the skin disease burden.
“a pattern dominated by a few conditions accounting for most of the skin disease burden.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
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In the citing paper
“Among the challenges in this field are the vast range of skin pathologies, with more than 2000 recognized skin diseases spanning from inflammatory dermatoses, infections, deposit disease, and neoplastic lesions [1].”
From Artificial Intelligence in Dermatopathology: An Update and Review of the Current Literature (2026) · cites this paper as [1]
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“These models have been proven to provide high sensitivity in the identification of malignant tumors and differentiation of various skin diseases thus being useful for dermatologists (6, 39, 40).”
From Revolutionizing dermatopathology using AI in skin diagnostics: scoping review (2026) · cites this paper as [39]
Experimental — accuracy not yet measuredIn the citing paper
“skin and subcutaneous disorders were the 4th leading cause of nonfatal disease burden worldwide in 2010 and 2013”
From Global Burden of Skin Disease: Inequities and Innovations (2017) · cites this paper as [4]
In the citing paper
“the GBD is based on the ICD classification system, which leads to categorization of certain skin conditions under other entities, for example, melanoma is classified under “cancer.””
From Global Burden of Skin Disease: Inequities and Innovations (2017) · cites this paper as [4]
In the citing paper
“The effects of skin conditions on QoL in resource-replete settings is profound and well-documented”
From Global Burden of Skin Disease: Inequities and Innovations (2017) · cites this paper as [4]
In the citing paper
“the dermatological manifestations of systemic illnesses are not necessarily individually categorized; the burden of lupus erythematosus is therefore entirely included under that of musculoskeletal disease”
From Global Burden of Skin Disease: Inequities and Innovations (2017) · cites this paper as [4]
Citations
Cites
Lozano, R., Naghavi, M., Foreman, K., Lim, S., Shibuya, K., Aboyans, V., Abraham, J., Adair, T., Aggarwal, R., Ahn, S. Y., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61728-0 · Cited by 14,070
Self-citationVos, T., Flaxman, A. D., Naghavi, M., Lozano, R., Michaud, C., Ezzati, M., Shibuya, K., Salomon, J. A., Abdalla, S., Aboyans, V., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61729-2 · Cited by 8,291
Self-citation(1996) · Cited by 6,884
Self-citationSalomon, J. A., Vos, T., Hogan, D. R., Gagnon, M., Naghavi, M., Mokdad, A., Begum, N., Shah, R., Karyana, M., Kosen, S., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61680-8 · Cited by 1,322
Self-citationWILLIAMS, H. C., JBURNEY, P. G., HAY, R. J., ARCHER, C. B., SHIPLEY, M. J., AHUNTER, J. J., BINGHAM, E. A., FINLAY, A. Y., PEMBROKE, A. C., CGRAHAM-BROWN, R. A., et al. (1994) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1994.tb08530.x · Cited by 1,271
Self-citationMeta-analysis of risk factors for cutaneous melanoma: II. Sun exposure
Gandini, S., Sera, F., Cattaruzza, M. S., Pasquini, P., Picconi, O., Boyle, P., & Melchi, C. F. (2005) · European Journal of Cancer · doi:10.1016/j.ejca.2004.10.016 · Cited by 1,266
Bickers (2006) · doi:10.1016/j.jaad.2006.05.048 · Cited by 741
Self-citationUK health performance: findings of the Global Burden of Disease Study 2010
Murray, C. J., Richards, M. A., Newton, J. N., Fenton, K. A., Anderson, H. R., Atkinson, C., Bennett, D., Bernabé, E., Blencowe, H., Bourne, R., et al. (2013) · The Lancet · doi:10.1016/s0140-6736(13)60355-4 · Cited by 553
Self-citationIs eczema really on the increase worldwide?
Williams, H. C., Stewart, A. W., von Mutius, E., Cookson, W., & Anderson, H. R. (2007) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2007.11.004 · Cited by 530
Self-citationThe Medical Expenditure Panel Survey
Cohen, J. W., Cohen, S. B., & Banthin, J. S. (2009) · Medical Care · doi:10.1097/mlr.0b013e3181a23e3a · Cited by 343
Flagged first, then by citations
3 of the 31 references couldn’t be matched to a known paper.
Research works printed but not linked: 5
- Global Burden of Disease: 2004 Update, 2008, Global Burden of Disease
- Mahe, 2005, Epidemiology and Management of Common Skin Diseases in Children in Developing Countries. WHO
- NHANES, 1978, Skin conditions and related need for medical care among persons 1–74 years . NHANES:, United States, 1971–1974 DHEW Publication 1978 No. (PHS),, pp 79
- Royal College of General Practitioners Research Unit (UK), 2010, Royal College of General Practitioners Research Unit (UK)
- Scholfield, 2009, Skin Conditions in the UK: A Health Needs Assessment
Cited by
Sorted by citations
Vos, T., Barber, R. M., Bell, B., Bertozzi-Villa, A., Biryukov, S., Bolliger, I., Charlson, F., Davis, A., Degenhardt, L., Dicker, D., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(15)60692-4 · Cited by 6,414
Self-citationThe JAK/STAT signaling pathway: from bench to clinic
Hu, X., li, J., Fu, M., Zhao, X., & Wang, W. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00791-1 · Cited by 2,633
“The prevalence ranges from 5 to 20%.(289,290) The incidence tends to be higher in children than adults.”
BackgroundLangan, S., Irvine, A. D., & Weidinger, S. (2020) · The Lancet · doi:10.1016/s0140-6736(20)31286-1 · Cited by 1,996
Weidinger, S., Beck, L. A., Bieber, T., Kabashima, K., & Irvine, A. D. (2018) · Nature Reviews Disease Primers · doi:10.1038/s41572-018-0001-z · Cited by 1,549
National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study
Parisi, R., Iskandar, I. Y. K., Kontopantelis, E., Augustin, M., Griffiths, C. E. M., & Ashcroft, D. M. (2020) · BMJ · doi:10.1136/bmj.m1590 · Cited by 1,270
Advances in skin grafting and treatment of cutaneous wounds
Sun, B. K., Siprashvili, Z., & Khavari, P. A. (2014) · Science · doi:10.1126/science.1253836 · Cited by 972
Dalgard, F. J., Gieler, U., Tomas-Aragones, L., Lien, L., Poot, F., Jemec, G. B. E., Misery, L., Szabo, C., Linder, D., Sampogna, F., et al. (2015) · Journal of Investigative Dermatology · doi:10.1038/jid.2014.530 · Cited by 968
“The Global Burden of Diseases Study recently demonstrated that skin diseases were the fourth leading cause of nonfatal disease burden (Hay et al., 2014).”
BackgroundA deep learning system for differential diagnosis of skin diseases
Liu, Y., Jain, A., Eng, C., Way, D. H., Lee, K., Bui, P., Kanada, K., de Oliveira Marinho, G., Gallegos, J., Gabriele, S., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-0842-3 · Cited by 853
“Considerations during this mapping were a granularity that would (1) allow a non-dermatology clinician to reasonably determine the next steps in clinical care, (2) enable clear and concise communication with another healthcare provider, and (3) exclude superfluous information for most purposes (e.”
A global perspective on the epidemiology of acne
Tan, J. K. L., & Bhate, K. (2015) · British Journal of Dermatology · doi:10.1111/bjd.13462 · Cited by 844
Global Skin Disease Morbidity and Mortality: An Update From the Global Burden of Disease Study 2013
Karimkhani, C., Dellavalle, R. P., Coffeng, L. E., Flohr, C., Hay, R. J., Langan, S. M., Nsoesie, E. O., Ferrari, A. J., Erskine, H. E., Silverberg, J. I., et al. (2017) · JAMA Dermatology · doi:10.1001/jamadermatol.2016.5538 · Cited by 742
“J Eur Acad Dermatol Venereol 2007;21(5):643-9.”
Self-citationMartinengo, L., Olsson, M. M., Bajpai, R. C., Soljak, M., Upton, Z., Schmidtchen, A., Car, J., & Järbrink, K. (2018) · Annals of Epidemiology · doi:10.1016/j.annepidem.2018.10.005 · Cited by 778
Tobin, D. J. (2017) · Journal of Tissue Viability · doi:10.1016/j.jtv.2016.03.002 · Cited by 701
The gut microbiome as a major regulator of the gut-skin axis
Salem, I., Ramser, A., Isham, N., & Ghannoum, M. A. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01459 · Cited by 707
Epidemiological trends in skin cancer
Apalla, Z., Lallas, A., Sotiriou, E., Lazaridou, E., & Ioannides, D. (2017) · Dermatology Practical & Conceptual · doi:10.5826/dpc.0702a01 · Cited by 583
The burden of skin disease in the United States
Lim, H. W., Collins, S. A. B., Resneck, J., Bolognia, J. L., Hodge, J. A., Rohrer, T. E., Beek, M. J. V., Margolis, D. J., Sober, A. J., Weinstock, M. A., et al. (2017) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2016.12.043 · Cited by 524
“S kin disease is one of the leading causes of global disease burden, affecting millions of people worldwide.(1) Aging, environmental and genetic factors, and trauma can result in the development of a diverse set of skin diseases, with over 3000 entities identified in the literature.”
BackgroundSelf-citationPrevalence and Incidence of Atopic Dermatitis: A Systematic Review
Bylund, S., von Kobyletzki, L. B., Svalstedt, M., & Svensson, �. (2020) · Acta Dermato Venereologica · doi:10.2340/00015555-3510 · Cited by 536
Guidelines of care for the management of acne vulgaris
Reynolds, R. V., Yeung, H., Cheng, C. E., Cook-Bolden, F., Desai, S. R., Druby, K. M., Freeman, E. E., Keri, J. E., Stein Gold, L. F., Tan, J. K. L., et al. (2024) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2023.12.017 · Cited by 518
Tuchayi, S. M., Makrantonaki, E., Ganceviciene, R., Dessinioti, C., Feldman, S. R., & Zouboulis, C. C. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.29 · Cited by 432
Fuxench, Z. C. C., Block, J. K., Boguniewicz, M., Boyle, J. M., Fonacier, L. S., Gelfand, J. M., Grayson, M. H., Margolis, D. J., Mitchell, L., Silverberg, J. I., et al. (2018) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2018.08.028 · Cited by 420
Self-citationReich, K., Teixeira, H. D., de Bruin-Weller, M., Bieber, T., Soong, W., Kabashima, K., Werfel, T., Zeng, J., Huang, X., Hu, X., et al. (2021) · The Lancet · doi:10.1016/s0140-6736(21)00589-4 · Cited by 402
Paller, A. S., Siegfried, E. C., Thaçi, D., Wollenberg, A., Cork, M. J., Arkwright, P. D., Gooderham, M., Beck, L. A., Boguniewicz, M., Sher, L., et al. (2020) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2020.06.054 · Cited by 412
“Superscript numbers (1-22) show the order in the statistical testing hierarchy; all P-values in the hierarchy were controlled for multiplicity.”
BackgroundBurden and socioeconomics of asthma, allergic rhinitis, atopic dermatitis and food allergy
Dierick, B. J. H., van der Molen, T., Blok, B. M. J. F.-D., Muraro, A. M., Postma, M. J., Kocks, J. W. H., & van Boven, J. F. M. (2020) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1080/14737167.2020.1819793 · Cited by 385
“This is because of the high prevalence worldwide and the relatively high average disability weight [118].”
BackgroundGlobal Burden of Skin Disease: Inequities and Innovations
Seth, D., Cheldize, K., Brown, D., & Freeman, E. E. (2017) · Current Dermatology Reports · doi:10.1007/s13671-017-0192-7 · Cited by 366
Karimkhani, C., Colombara, D. V., Drucker, A. M., Norton, S. A., Hay, R. J., Engelman, D., Steer, A. C., Whitfeld, M. J., Naghavi, M., & Dellavalle, R. P. (2017) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(17)30483-8 · Cited by 363
Self-citationBowen, A. C., Mahé, A., Hay, R. J., Andrews, R. M., Steer, A. C., Tong, S. Y. C., & Carapetis, J. R. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136789 · Cited by 334
“Recent estimates of the global burden of impetigo are 111 million children from developing countries [1] to 140 million [2, 3] people affected at any one time.”
BackgroundInfluentialSelf-citationWu, H., Li, F., Wang, S., Lu, J., Li, J., Du, Y., Sun, X., Chen, X. S., Gao, J., & Ling, D. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.10.018 · Cited by 346
Association of Atopic Dermatitis With Sleep Quality in Children
Ramirez, F. D., Chen, S., Langan, S., Prather, A. A., McCulloch, C. E., Kidd, S. A., Cabana, M. D., Chren, M., & Abuabara, K. (2019) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2019.0025 · Cited by 329
“A topic dermatitis ranks among the largest components of the nonfatal disease burden worldwide.(1) Sleep disturbances have been identified as central to qualityof-life decrements in atopic dermatitis,(2,3) but little is known about their association with sleep in the general population.”
The role of IL ‐23 and the IL ‐23/ T H 17 immune axis in the pathogenesis and treatment of psoriasis
Girolomoni, G., Strohal, R., Puig, L., Bachelez, H., Barker, J. N., Boehncke, W., & Prinz, J. C. (2017) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.14433 · Cited by 329
Torres, T. R., Ferreira, E. O., Gonçalo, M., Mendes‐Bastos, P., Selores, M., & Filipe, P. (2019) · Acta Médica Portuguesa · doi:10.20344/amp.11963 · Cited by 306
Eckert, L., Gupta, S., Amand, C., Gadkari, A. S., Mahajan, P. S., & Gelfand, J. M. (2017) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2017.04.019 · Cited by 239
“considered in published reports of disability.(10,11) In totality, these implications are alarming and underscore the public health concerns of AD reported in global epidemiologic studies.”
BackgroundInfluentialElectronic textiles: New age of wearable technology for healthcare and fitness solutions
Meena, J. S., Choi, S. B., Jung, S., & Kim, J. (2023) · Materials Today Bio · doi:10.1016/j.mtbio.2023.100565 · Cited by 266
Epidemiology of adult atopic dermatitis
Sacotte, R. M., & Silverberg, J. I. (2018) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2018.05.007 · Cited by 235
Treatment of atopic dermatitis with ruxolitinib cream (JAK1/JAK2 inhibitor) or triamcinolone cream
Kim, B. S., Howell, M. D., Sun, K., Papp, K., Nasir, A., & Kuligowski, M. E. (2020) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2019.08.042 · Cited by 226
“The Global Burden of Disease project identified AD as one of the most common diseases worldwide, increasing in prevalence, and having the second highest disability rank of all nonmalignant skin diseases.(6) Despite the significant impact of medical, quality of life, and cost of AD on society,(1) treatments remain limi…”
BackgroundZaenglein, A. L. (2018) · New England Journal of Medicine · doi:10.1056/nejmcp1702493 · Cited by 225
Age-associated skin conditions and diseases: Current perspectives and future options
Blume-Peytavi, U., Kottner, J., Sterry, W., Hodin, M. W., Griffiths, T. W., Watson, R. E. B., Hay, R. J., & Griffiths, C. E. M. (2016) · The Gerontologist · doi:10.1093/geront/gnw003 · Cited by 221
“This finding is supported by the latest Global Burden of Disease Study (2010), where the years lost due to disability caused by skin conditions were highest in the aged (Hay et al., 2014).”
BackgroundResultSelf-citationMcLaughlin, J. B., Watterson, S., Layton, A., Bjourson, A. J., Barnard, E., & McDowell, A. (2019) · Microorganisms · doi:10.3390/microorganisms7050128 · Cited by 233
“The chronic inflammatory and recurrent skin condition acne vulgaris, commonly referred to as acne, is a disease of the pilosebaceous unit (hair, hair follicle, erector pili muscle and sebaceous gland) and, strikingly, the eighth most prevalent disease globally, affecting approximately 10% of the world’s population [35…”
BackgroundCounting the Burden: Atopic Dermatitis and Health-related Quality of Life
Ali, F. M., Vyas, J., & Finlay, A. Y. (2020) · Acta Dermato Venereologica · doi:10.2340/00015555-3511 · Cited by 221
“Using DALYs, the global burden of skin disease survey revealed that eczema causes the highest burden of all skin diseases worldwide (85).”
BackgroundPrevalence of most common skin diseases in Europe: a population‐based study
Richard, M. ‐., Paul, C. F., Nijsten, T. E. C., et al. (2022) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.18050 · Cited by 205
Advances in the Biofabrication of 3D Skin in vitro: Healthy and Pathological Models
Randall, M. J., Jüngel, A., Rimann, M., & Wuertz‐Kozak, K. (2018) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2018.00154 · Cited by 202
“The predominant types of skin diseases include fungal diseases, subcutaneous diseases, acne vulgaris, pruritus, eczema, impetigo, molluscum contagiosum/warts, and scabies (Hay et al., 2014).”
BackgroundAjjoun, M., Kharchoufa, L., Merrouni, I. A., & Elachouri, M. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115532 · Cited by 198
A Benchmark for Automatic Visual Classification of Clinical Skin Disease Images
Sun, X., Yang, J., Sun, M., & Wang, K. (2016) · Lecture Notes in Computer Science · doi:10.1007/978-3-319-46466-4_13 · Cited by 197
“It pervades all cultures, occurs at all ages, and affects between 30% and 70% of individuals [1].”
BackgroundIntegrated Control and Management of Neglected Tropical Skin Diseases
Mitjà, O., Marks, M., Bertran, L., Kollie, K., Argaw, D., Fahal, A. H., Fitzpatrick, C., Fuller, L. C., Garcia Izquierdo, B., Hay, R., et al. (2017) · PLOS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0005136 · Cited by 183
“[10] For example, contractures and resulting disability in BU, advanced lymphoedema and hydrocele in LF, the consequences of permanent nerve damage in leprosy, amputations in mycetoma, and bone involvement in yaws can lead to debilitating deformities and difficulty in securing employment.[11] In addition, skin NTDs re…”
BackgroundSelf-citationVekemans, J., Gouvea-Reis, F., Kim, J. H., Excler, J., Smeesters, P. R., O’Brien, K. L., Beneden, C. V., Steer, A. C., Carapetis, J. R., & Kaslow, D. C. (2019) · Clinical Infectious Diseases · doi:10.1093/cid/ciy1143 · Cited by 176
“Implications on the vaccine evaluations should be further considered [38].”
BackgroundThe epidemiology of skin conditions in the aged: A systematic review
Hahnel, E., Lichterfeld, A., Blume‐Peytavi, U., & Kottner, J. (2016) · Journal of Tissue Viability · doi:10.1016/j.jtv.2016.04.001 · Cited by 174
“For example non-melanoma skin cancer, pressure ulcers or fungal skin diseases have in comparison to younger age groups growing disability-adjusted life years lost by 100,000 [14] overall.”
BackgroundMethodPre-trained multimodal large language model enhances dermatological diagnosis using SkinGPT-4
Zhou, J., He, X., Sun, L., Xu, J., Chen, X., Chu, Y., Zhou, L., Liao, X., Zhang, B., Afvari, S., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-50043-3 · Cited by 189
“Skin and subcutaneous diseases rank as the fourth major cause of nonfatal disease burden worldwide, affecting a considerable proportion of individuals,with a prevalenceranging from 30 to 70% across all ages and regions 1 .”
The global state of psoriasis disease epidemiology: a workshop report
Griffiths, C. E. M., van der Walt, J. M., Ashcroft, D. M., Flohr, C., Naldi, L., Nijsten, T. E. C., & Augustin, M. (2017) · British Journal of Dermatology · doi:10.1111/bjd.15610 · Cited by 172
Self-citationReviewing the global burden of acne: how could we improve care to reduce the burden?*
Layton, A., Thiboutot, D. M., & Tan, J. K. L. (2020) · British Journal of Dermatology · doi:10.1111/bjd.19477 · Cited by 173
Mueller, S. M., Hongler, V. N. S., Jungo, P., Cajacob, L., Schwegler, S., Steveling, E. H., Thomas, Z. M., Fuchs, O., Navarini, A. A., Scherer, K., et al. (2020) · Journal of Medical Internet Research · doi:10.2196/15599 · Cited by 171
“Patients with AD have a high motivation to conduct online searches, and this usually correlates with disease burden [39,40].”
BackgroundStudies on Different CNN Algorithms for Face Skin Disease Classification Based on Clinical Images
Wu, Z., Zhao, S., Peng, Y., He, X., Zhao, X., Huang, K., Wu, X., Fan, W., Li, F., Chen, M., et al. (2019) · IEEE Access · doi:10.1109/access.2019.2918221 · Cited by 177
Hossen, M. N., Panneerselvam, V., Koundal, D., Ahmed, K., Bui, F. M., & Ibrahim, S. M. (2022) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2022.3149288 · Cited by 180
“According to the Global Burden of Disease (GBD) Study 2010 [1], in the cause of nonfatal diseases in the world as a burden, skin disease was fourth on the list of most common diseases.”
MethodPlant-Derived Products as Antibacterial and Antifungal Agents in Human Health Care
Kokoška, L., Klouček, P., Leuner, O., & Nový, P. (2018) · Current Medicinal Chemistry · doi:10.2174/0929867325666180831144344 · Cited by 165
Putting the burden of skin diseases on the global map
Flohr, C., & Hay, R. J. (2021) · British Journal of Dermatology · doi:10.1111/bjd.19704 · Cited by 164
Self-citationMSCA-Net: Multi-scale contextual attention network for skin lesion segmentation
Sun, Y., Dai, D.-W., Zhang, Q.-N., Wang, Y.-Q., Xu, S.-Y., & Lian, C. (2023) · Pattern Recognition · doi:10.1016/j.patcog.2023.109524 · Cited by 142
Host immune responses to the itch mite, Sarcoptes scabiei, in humans
Bhat, S. A., Mounsey, K. E., Liu, X., & Walton, S. F. (2017) · Parasites & Vectors · doi:10.1186/s13071-017-2320-4 · Cited by 146
“It was reported in 2010 that about 100 million of the global population is infected with scabies [2] and prevalence in different regions ranged from 0.”
BackgroundTREM2 macrophages induced by human lipids drive inflammation in acne lesions
Do, T. H., Ma, F., Andrade, P. R., Teles, R., de Andrade Silva, B. J., Hu, C., Espinoza, A., Hsu, J.-E., Cho, C.-S., Kim, M., et al. (2022) · Science Immunology · doi:10.1126/sciimmunol.abo2787 · Cited by 139
Williams, H. C., Bath-Hextall, F. J., Ozolins, M., Armstrong, S., Colver, G., Perkins, W. A., & Miller, P. S. J. (2016) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2016.10.019 · Cited by 138
“, 2015), yet poor registration of BCC makes it difficult to compare estimates across the world (Hay et al., 2014).”
BackgroundSelf-citationSevere Dermatophytosis and Acquired or Innate Immunodeficiency: A Review
Rouzaud, C., Hay, R. J., Chosidow, O., et al. (2015) · Journal of Fungi · doi:10.3390/jof2010004 · Cited by 133
“They affect 20% to 25% of the world’s population and represent the fourth most prevalent of human diseases [1–3].”
BackgroundSelf-citationOpportunities for Integrated Control of Neglected Tropical Diseases That Affect the Skin
Engelman, D., Fuller, L. C., Solomon, A. W., McCarthy, J. S., Hay, R. J., Lammie, P. J., & Steer, A. C. (2016) · Trends in Parasitology · doi:10.1016/j.pt.2016.08.005 · Cited by 128
“The disease burden is conservatively estimated at 100 million cases at any time [11], but prevalence data from most regions remain patchy.”
BackgroundSelf-citationSalzes, C., Abadie, S., Sénéschal, J., Whitton, M. E., Meurant, J. ‐., Jouary, T., Ballanger, F., Boralévi, F., Taı̈eb, A., TAIEB, C., et al. (2015) · Journal of Investigative Dermatology · doi:10.1038/jid.2015.398 · Cited by 131
Lou, D., Pang, Q., Pei, X., Dong, S., Li, S., Tan, W., & Ma, L. (2020) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2020.112275 · Cited by 135
Goodarzi, A., Mozafarpoor, S., Bodaghabadi, M., & Mohamadi, M. (2020) · Dermatologic Therapy · doi:10.1111/dth.13279 · Cited by 130
“As a prevalent disease in adolescents and adults and one of the 10 most prevalent disorders in the world, acne affects 47–90% of adolescents and the young (Cooper, 1998; Hay et al., 2014; Patel, Bowe, Heughebaert, & Shalita, 2010; Perkins, Maglione, Hillebrand, Miyamoto, & Kimball, 2012).”
BackgroundUpadacitinib plus topical corticosteroids in atopic dermatitis: Week 52 AD Up study results
Silverberg, J. I., de Bruin-Weller, M. S., Bieber, T. R. M., Soong, W., Kabashima, K., Costanzo, A., Rosmarin, D. M., Lynde, C. W., Liu, J., Gamelli, A., et al. (2021) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2021.07.036 · Cited by 130
Oral spironolactone for acne vulgaris in adult females: a hybrid systematic review
Layton, A. M., Eady, E. A., Whitehouse, H., Del Rosso, J. Q., Fedorowicz, Z., & van Zuuren, E. J. (2017) · American Journal of Clinical Dermatology · doi:10.1007/s40257-016-0245-x · Cited by 126
“1 Introduction Acne is the eighth most prevalent disease globally [1].”
BackgroundFerreira, S., Guttman‐Yassky, E., & Torres, T. R. (2020) · American Journal of Clinical Dermatology · doi:10.1007/s40257-020-00548-6 · Cited by 128
Zagórska-Dziok, M., & Sobczak, M. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12050396 · Cited by 126
Itch: Epidemiology, clinical presentation, and diagnostic workup
Roh, Y. S., Choi, J., Sutaria, N. H., & Kwatra, S. G. (2021) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2021.07.076 · Cited by 122
The Prevalence of Scabies and Impetigo in the Solomon Islands: A Population-Based Survey
Mason, D. S., Marks, M., Sokana, O., Solomon, A. W., Mabey, D. C. W., Romani, L., Kaldor, J. M., Steer, A. C., & Engelman, D. (2016) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0004803 · Cited by 114
Ewald, D. A., Noda, S., Oliva, M., Litman, T., Nakajima, S., Li, X., Xu, H., Workman, C. T., Scheipers, P., Svitacheva, N., et al. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.08.029 · Cited by 114
Prevalence of skin disease in a population-based sample of adults from five European countries
Svensson, Å., Ofenloch, R. F., Bruze, M., Naldi, L., Cazzaniga, S., Elsner, P. U., Gonçalo, M., Schuttelaar, M. L. A., & Diepgen, T. L. (2017) · British Journal of Dermatology · doi:10.1111/bjd.16248 · Cited by 117
Self-citationNaka, F., Lu, J., Porto, A. F., Villagra, J. D., Wu, Z. H., & Anderson, D. (2017) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2017.09.017 · Cited by 110
Clinical Skin Lesion Diagnosis Using Representations Inspired by Dermatologist Criteria
Yang, J., Sun, X., Liang, J., & Rosin, P. L. (2018) · IEEE Computer Society Conference on Computer Vision and Pattern Recognition/Proceedings - IEEE Computer Society Conference on Computer Vision and Pattern Recognition/Proceedings · doi:10.1109/cvpr.2018.00137 · Cited by 126
“It pervades all cultures, occurs at all ages, and affects the health of 30% to 70% of individuals, with even higher rates for the at-risk subpopulations [21, 22].”
BackgroundImplications of climate variability and change on urban and human health: A review
Orimoloye, I. R., Mazinyo, S. P., Kalumba, A. M., Ekundayo, O. Y., & Nel, W. (2019) · Cities · doi:10.1016/j.cities.2019.01.009 · Cited by 115
Eckert, L., Gupta, S., Gadkari, A., Mahajan, P., & Gelfand, J. M. (2019) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2019.03.037 · Cited by 113
Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis
Mack, M. R., Brestoff, J. R., Berrien-Elliott, M. M., Trier, A. M., Yang, T.-L. B., McCullen, M. V. D., Collins, P. L., Niu, H., Bodet, N. D., Wagner, J. A., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aay1005 · Cited by 109
Self-citationAssociation Between Malignancy and Topical Use of Pimecrolimus
Margolis, D. J., Abuabara, K., Hoffstad, O., Wan, J., Raimondo, D., & Bilker, W. B. (2015) · JAMA Dermatology · doi:10.1001/jamadermatol.2014.4305 · Cited by 112
Self-citationBurden of atopic dermatitis in Asia
Tsai, T., Rajagopalan, M., Chu, C., Encarnacion, L., Gerber, R. A., Santos‐Estrella, P., Llamado, L. J. Q., & Tallman, A. M. (2019) · The Journal of Dermatology · doi:10.1111/1346-8138.15048 · Cited by 103
Eddin, L. B., Jha, N. K., Goyal, S. N., Agrawal, Y. O., Subramanya, S. B., Bastaki, S. M. A., & Ojha, S. K. (2022) · Nutrients · doi:10.3390/nu14071370 · Cited by 120
“α-Bisabolol and Skin Disorders Skin diseases are among the common illnesses affecting humans at all ages and imposing a huge burden on the global health system [35].”
BackgroundAssessment of severity and burden of pruritus
Pereira, M. P., & Ständer, S. (2016) · Allergology International · doi:10.1016/j.alit.2016.08.009 · Cited by 113
Oncostatin M can sensitize sensory neurons in inflammatory pruritus
Tseng, P., & Hoon, M. A. (2021) · Science Translational Medicine · doi:10.1126/scitranslmed.abe3037 · Cited by 111
Human and Zoonotic Dermatophytoses: Epidemiological Aspects
Segal, E., & Elad, D. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.713532 · Cited by 108
Disease modification in inflammatory skin disorders: opportunities and challenges
Bieber, T. R. M. (2023) · Nature Reviews Drug Discovery · doi:10.1038/s41573-023-00735-0 · Cited by 120
Kim, B., Sun, K., Papp, K. A., Venturanza, M. E., Nasir, A., & Kuligowski, M. E. (2020) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2020.02.009 · Cited by 109
Deciphering UV‐induced DNA Damage Responses to Prevent and Treat Skin Cancer
Lee, J. W., Ratnakumar, K., Hung, K., Rokunohe, D., & Kawasumi, M. (2020) · Photochemistry and Photobiology · doi:10.1111/php.13245 · Cited by 121
Huang, F., Lu, X., Kuai, L., Ru, Y., Jiang, J., Song, J., Chen, S., Mao, L., Li, Y., Li, B., et al. (2024) · Journal of the American Chemical Society · doi:10.1021/jacs.3c11059 · Cited by 114
Penso, L., Touvier, M., Deschasaux, M., Szabo de edelenyi, F., Hercberg, S., Ezzedine, K., & Sbidian, E. (2020) · JAMA Dermatology · doi:10.1001/jamadermatol.2020.1602 · Cited by 115
Castillo, D. E., Nanda, S., & Keri, J. E. (2018) · Dermatology and Therapy · doi:10.1007/s13555-018-0275-9 · Cited by 103
Systematic Review of Deep Learning Image Analyses for the Diagnosis and Monitoring of Skin Disease
Choy, S. P., Kim, B. J., Paolino, A., Tan, W. R., Lim, S. M. L., Seo, J., Tan, S. P., Francis, L., Tsakok, T., Simpson, M., et al. (2023) · npj Digital Medicine · doi:10.1038/s41746-023-00914-8 · Cited by 105
Bernigaud, C., Fang, F., Fischer, K., Lespine, A., Aho, S., Dreau, D., Kelly, A., Sutra, J., Moreau, F., Lilin, T., et al. (2016) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0005030 · Cited by 102
Steinke, S., Zeidler, C., Riepe, C., Bruland, P., Soto‐Rey, I., Storck, M., Augustin, M., Ивановна, Б. С., Garcovich, S., Legat, F. J., et al. (2018) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2018.04.044 · Cited by 104
Tizek, L., Schielein, M. C., Seifert, F., Biedermann, T., Böhner, A., & Zink, A. (2019) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.15494 · Cited by 108
Urban, K., Chu, S., Giesey, R. L., Mehrmal, S., Uppal, P., Nedley, N., & Delost, G. R. (2020) · JAAD International · doi:10.1016/j.jdin.2020.10.002 · Cited by 98
Expanding the applications of microneedles in dermatology
Sabri, A. H. B., Ogilvie, J., Hamid, K. A., Shpadaruk, V., McKenna, J., Segal, J. I., Scurr, D. J., & Marlow, M. (2019) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2019.05.001 · Cited by 103
Zakrewsky, M., Kumar, S., & Mitragotri, S. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.09.017 · Cited by 99
JAK/STAT inhibitors for the treatment of atopic dermatitis
Rodrigues, M. A., & Torres, T. (2020) · Journal of Dermatological Treatment · doi:10.1080/09546634.2019.1577549 · Cited by 97
“According to WHO Global Burden of Diseases initiative at least 230 million people worldwide have AD (1) making it the leading cause of non-fatal disease burden of skin conditions (2).”
BackgroundEpidemiology of major chronic inflammatory immune-related skin diseases in 2019
Pezzolo, E., & Naldi, L. (2020) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2020.1719833 · Cited by 96
“The project is ongoing and has provided a mass of data on the impact of hundreds of disorders, injuries, and risk factors in 187 countries [107].”
BackgroundSelf-citationAssociation Between Atopic Eczema and Cancer in England and Denmark
Mansfield, K. E., Schmidt, S. A. J., Darvalics, B., Mulick, A. R., Abuabara, K., Wong, A. Y. S., Sørensen, H. T., Smeeth, L. L., Bhaskaran, K., dos‐Santos‐Silva, I., et al. (2020) · JAMA Dermatology · doi:10.1001/jamadermatol.2020.1948 · Cited by 93
Management of cutaneous viral warts
Lynch, M., Cliffe, J., & Morris‐Jones, R. (2014) · BMJ · doi:10.1136/bmj.g3339 · Cited by 94
Health Care Utilization, Patient Costs, and Access to Care in US Adults With Eczema
Silverberg, J. I. (2015) · JAMA Dermatology · doi:10.1001/jamadermatol.2014.5432 · Cited by 93
Janus kinase inhibitors for the therapy of atopic dermatitis
Traidl, S., Freimooser, S., & Werfel, T. (2021) · Allergologie select · doi:10.5414/alx02272e · Cited by 89
“Considering the lost healthy life years (DALY = disability-adjusted life years), AD represents the skin disease with the strongest impairment of life expectancy in good health [3].”
BackgroundGlobal Disease Burden of Group A Streptococcus
Sanyahumbi, A., Colquhoun, S., Wyber, R., & Carapetis, J. R. (2016) · Europe PMC (PubMed Central) · Cited by 102
Metadata
- Authors
- Hay, R. J., Johns, N. E., Williams, H. C., Bolliger, I. W., Dellavalle, R. P., Margolis, D. J., Marks, R., Naldi, L., Weinstock, M. A., Wulf, S. K., Michaud, C., J.L. Murray, C., & Naghavi, M.
- Affiliations
- University of Washington (US)
- University of Nottingham (GB)
- Denver VA Medical Center (US)
- University of Pennsylvania (US)
- Skin and Cancer Foundation (AU)
- Ospedale Papa Giovanni XXIII (IT)
- Brown University (US)
- China Medical Board (US)
- Corresponding author
- Hay, Roderick J.
- ORCID
- Venue
- Journal of Investigative Dermatology
- Publisher
- Elsevier BV
- Published
- 2014-06
- Volume
- 134
- Issue
- 6
- Pages
- 1527-1534
- ISSN
- 0022-202X (ISSN-L)
- OpenAlex
- W2051521434
- Semantic Scholar
- 5f720423986eece0d00d0b522e9e594f0a7ca829
- Cited by
- 1,706
- References
- 31
- Citations by year
- 2026: 144 · 2025: 178 · 2024: 185 · 2023: 202 · 2022: 201 · 2021: 144 · 2020: 166 · 2019: 116 · 2018: 113 · 2017: 90 · 2016: 86 · 2015: 57 · 2014: 21
- FWCI
- 64.17
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Investigative Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Repository@Nottingham (University of Nottingham) (submittedVersion, cc-by)
- INFM-OAR (INFN Catania) (submittedVersion, other-oa)
- Funders
- Bill and Melinda Gates Foundation
- Topics
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Infectious Diseases › Dermatological diseases and infestations
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Health and Epidemiology
- Keywords
- skin diseases, global burden of disease, prevalence, years lived with disability, atopic dermatitis, psoriasis, acne, pruritus, alopecia areata, pressure ulcers, urticaria, scabies, fungal skin infection, impetigo, bacterial skin infections, cellulitis, viral warts, molluscum contagiosum, non-melanoma skin cancer
- MeSH terms
- Dermatology, Female, Disabled Persons, Persons with Disabilities, Humans, Male, Mortality, Skin, Skin Diseases, Skin Neoplasms, Global Health, Prevalence, Cost of Illness, Quality-Adjusted Life Years
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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