Wnt proteins are lipid-modified and can act as stem cell growth factors

Large-scale analysis of the yeast proteome by multidimensional protein identification technology

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Phase separation of integral membrane proteins in Triton X-114 solution.

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Wnt signaling and cancer

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Wnt signaling: a common theme in animal development

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A role for Wnt signalling in self-renewal of haematopoietic stem cells

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The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells

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DTASelect and Contrast: Tools for Assembling and Comparing Protein Identifications from Shotgun Proteomics

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Identification of a Palmitic Acid-modified Form of Human Sonic hedgehog

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Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos

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Shotgun identification of protein modifications from protein complexes and lens tissue

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WNT signaling in the normal intestine and colorectal cancer

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Constitutive Activation of Wnt Signaling Favors Generation of Memory CD8 T Cells

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β-Catenin is essential for survival of leukemic stem cells insensitive to kinase inhibition in mice with BCR-ABL-induced chronic myeloid leukemia

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Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF

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Drosophila S2 Cells Secrete Wingless on Exosome‐Like Vesicles but the Wingless Gradient Forms Independently of Exosomes

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Wnt-Related Molecules and Signaling Pathway Equilibrium in Hematopoiesis

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Wnt signaling: multiple functions in neural development

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The endocytic pathway and formation of the Wingless morphogen gradient

Marois, É., Mahmoud, A., & Eaton, S. (2005) · Development · doi:10.1242/dev.02197 · Cited by 177

Role of wnts in prostate cancer bone metastases

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Autophagy and the Wnt signaling pathway: A focus on Wnt/β-catenin signaling

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Endogenous Wnt Signaling Maintains Neural Progenitor Cell Potency

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Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion

Zhang, J., He, X., Tong, W., Johnson, T., Wiedemann, L. M., Mishina, Y. M., Feng, J. Q., & Li, L. (2006) · Stem Cells · doi:10.1634/stemcells.2005-0544 · Cited by 178

Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome

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Wnt/Frizzled signaling in angiogenesis

Zerlin, M., Julius, M. A., & Kitajewski, J. (2008) · Angiogenesis · doi:10.1007/s10456-008-9095-3 · Cited by 172

Mesenchymal Stem Cells: Molecular Targets for Tissue Engineering

Satija, N. K., Gurudutta, G. U., Sharma, S., Afrin, F., Gupta, P., Verma, Y. K., Singh, V. K., & Tripathi, R. (2007) · Stem Cells and Development · doi:10.1089/scd.2006.9998 · Cited by 175

Brain Tumor Stem Cells: Bringing Order to the Chaos of Brain Cancer

Dirks, P. B. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2008.17.6792 · Cited by 170

The Role of Wnt Signalling in Angiogenesis.

Olsen, J. J., Pohl, S., Deshmukh, A. P., Visweswaran, M., Ward, N. C., Arfuso, F., Agostino, M., & Dharmarajan, A. (2017) · Europe PMC (PubMed Central) · Cited by 174

WntD is a feedback inhibitor of Dorsal/NF-κB in Drosophila development and immunity

Gordon, M. D., Dionne, M., Schneider, D. S., & Nusse, R. (2005) · Nature · doi:10.1038/nature04073 · Cited by 171

An ancient Wnt-Dickkopf antagonism inHydra

Guder, C., Pinho, S., Nacak, T. G., Schmidt, H. A., Hobmayer, B., Niehrs, C., & Holstein, T. W. (2006) · Development · doi:10.1242/dev.02265 · Cited by 168

The Wnt signaling pathway: Aging gracefully as a protectionist?

Maiese, K., Li, F., Chong, Z. Z., & Shang, Y. (2008) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2008.01.004 · Cited by 171

A Chondroitin Sulfate Small Molecule that Stimulates Neuronal Growth

Tully, S. E., Mabon, R., Gama, C. I., Tsai, S. M., Liu, X., & Hsieh‐Wilson, L. C. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0484045 · Cited by 180

Wnt signalling and the mechanistic basis of tumour development

Ilyas, M. (2005) · The Journal of Pathology · doi:10.1002/path.1692 · Cited by 171

Lipoprotein-Heparan Sulfate Interactions in the Hh Pathway

Eugster, C., Panáková, D., Mahmoud, A., & Eaton, S. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.04.019 · Cited by 169

Wnt your brain be inflamed? Yes, it Wnt!

Marchetti, B., & Pluchino, S. (2013) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2012.12.001 · Cited by 167

The chemical toolbox for monitoring protein fatty acylation and prenylation

Hannoush, R. N., & Sun, J. (2010) · Nature Chemical Biology · doi:10.1038/nchembio.388 · Cited by 169

Single-cell imaging of Wnt palmitoylation by the acyltransferase porcupine

Gao, X., & Hannoush, R. N. (2013) · Nature Chemical Biology · doi:10.1038/nchembio.1392 · Cited by 174

The role of the Wnt signaling pathway in osteoblast commitment and differentiation

Yavropoulou, M. P., & Yovos, J. G. (2007) · HORMONES · doi:10.14310/horm.2002.1111024 · Cited by 170

Novel Synthetic Antagonists of Canonical Wnt Signaling Inhibit Colorectal Cancer Cell Growth

Waaler, J., Machoň, O., von Kries, J. P., Wilson, S. R., Lundenes, E., Wedlich, D., Gradl, D., Paulsen, J. E., Machoňová, O., Dembinski, J. L., et al. (2011) · Cancer Research · doi:10.1158/0008-5472.can-10-1282 · Cited by 167

Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1

Malinauskas, T., Aricescu, A. R., Lu, W., Siebold, C., & Jones, E. Y. (2011) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2081 · Cited by 165

C‐terminal‐binding protein directly activates and represses Wnt transcriptional targets in Drosophila

Fang, M., Li, J., Blauwkamp, T. A., Bhambhani, C., Campbell, N. H., & Cadigan, K. M. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601153 · Cited by 164

Mechanisms of intercellular Wnt transport

Routledge, D., & Scholpp, S. (2019) · Development · doi:10.1242/dev.176073 · Cited by 146

Wnt/β-Catenin Signaling in Murine Hepatic Transit Amplifying Progenitor Cells

Hu, M., Kurobe, M., Jeong, Y. J., Fuerer, C., Ghole, S. A., Nusse, R., & Sylvester, K. G. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.08.036 · Cited by 164

A Positive Role of Cadherin in Wnt/β-Catenin Signalling during Epithelial-Mesenchymal Transition

Howard, S. M., Deroo, T., Fujita, Y., & Itasaki, N. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023899 · Cited by 163

Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble formPreprint

Creanga, A., Glenn, T. D., Mann, R. K., Saunders, A. M., Talbot, W. S., & Beachy, P. A. (2012) · Genes & Development · doi:10.1101/gad.191866.112 · Cited by 163

Dynamic Expression of Lgr5, a Wnt Target Gene, in the Developing and Mature Mouse Cochlea

Chai, R., Xia, A., Wang, T., Jan, T. A., Hayashi, T., Bermingham‐McDonogh, O., & Cheng, A. G.-L. (2011) · Journal of the Association for Research in Otolaryngology · doi:10.1007/s10162-011-0267-2 · Cited by 160

Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling

Rocha, P. P., Scholze‐Wittler, M., Bleiß, W., & Schrewe, H. (2010) · Development · doi:10.1242/dev.053660 · Cited by 170

Muscle-derived stem cells for musculoskeletal tissue regeneration and repair

Peng, H., & Huard, J. (2004) · Transplant Immunology · doi:10.1016/j.trim.2003.12.009 · Cited by 163

Spatial Regulation of Wingless Morphogen Distribution and Signaling by Dally-like Protein

Kirkpatrick, C. A., Dimitroff, B. D., Rawson, J. M., & Selleck, S. B. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.08.004 · Cited by 161

Initiation of Proximal-Distal Patterning in the Vertebrate Limb by Signals and Growth

Cooper, K. L., Hu, J. K., ten Berge, D., Fernandez‐Teran, M., Ros, M. A., & Tabin, C. J. (2011) · Science · doi:10.1126/science.1199499 · Cited by 160

The Wnt antagonist Dickkopf-1 and its receptors are coordinately regulated during early human adipogenesis

Christodoulides, C., Laudes, M., Cawthorn, W. P., Schinner, S., Soos, M. A., O’Rahilly, S., Sethi, J. K., & Vidal‐Puig, A. (2006) · Journal of Cell Science · doi:10.1242/jcs.02975 · Cited by 161

The Fibrillin‐1/VEGFR2/STAT2 signaling axis promotes chemoresistance via modulating glycolysis and angiogenesis in ovarian cancer organoids and cells

Wang, Z., Chen, W., Zuo, L., Xu, M., Wu, Y., Huang, J., Zhang, X., Li, Y., Wang, J., Chen, J., et al. (2022) · 癌症：英文版 · doi:10.1002/cac2.12274 · Cited by 157

Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo

Miao, Y., Ha, A., de Lau, W., Yuki, K., Santos, A. J. M., You, C., Geurts, M. H., Puschhof, J., Pleguezuelos-Manzano, C., Peng, W. C., et al. (2020) · Cell Stem Cell · doi:10.1016/j.stem.2020.07.020 · Cited by 151

Wnt10b Deficiency Promotes Coexpression of Myogenic and Adipogenic Programs in Myoblasts

Vertino, A. M., Taylor-Jones, J. M., Longo, K. A., Bearden, E. D., Lane, T. F., McGehee, R. E., MacDougald, O. A., & Peterson, C. A. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-08-0720 · Cited by 158

Mechanistic insights into Wnt–β-catenin pathway activation and signal transduction

Maurice, M. M., & Angers, S. (2025) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-024-00823-y · Cited by 180

Wnt Trafficking: New Insights into Wnt Maturation, Secretion and Spreading

Port, F., & Basler, K. (2010) · Traffic · doi:10.1111/j.1600-0854.2010.01076.x · Cited by 162

Stearoyl CoA Desaturase Is Required to Produce Active, Lipid-Modified Wnt Proteins

Rios-Esteves, J., & Resh, M. D. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.08.027 · Cited by 157

LeX is expressed by principle progenitor cells in the embryonic nervous system, is secreted into their environment and binds Wnt-1

Capela, A., & Temple, S. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2005.12.030 · Cited by 160

Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression

Reis, M., Czupalla, C. J., Ziegler, N., Devraj, K., Zinke, J., Seidel, S., Heck, R., Thom, S., Macas, J., Bockamp, E., et al. (2012) · Journal of Experimental Medicine · doi:10.1084/jem.20111580 · Cited by 167

HSC Niche Biology and HSC Expansion Ex Vivo

Kumar, S., & Geiger, H. (2017) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2017.07.003 · Cited by 174

Embryonic origins of mammalian hematopoiesis

Baron, M. H. (2003) · Experimental Hematology · doi:10.1016/j.exphem.2003.08.019 · Cited by 153

Clinical strategies for expansion of haematopoietic stem cells

Sorrentino, B. P. (2004) · Nature reviews. Immunology · doi:10.1038/nri1487 · Cited by 154

Notch and Wnt inhibitors as potential new drugs for intestinal neoplastic disease

van Es, J. H., & Clevers, H. C. (2005) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2005.09.008 · Cited by 152

Aurora-A/SOX8/FOXK1 signaling axis promotes chemoresistance via suppression of cell senescence and induction of glucose metabolism in ovarian cancer organoids and cells

Sun, H., Wang, H., Wang, X., Aoki, Y., Wang, X., Wang, Z., Cheng, X., Wang, Z., & Wang, X. (2020) · Theranostics · doi:10.7150/thno.43811 · Cited by 154

Winding through the WNT pathway during cellular development and demise.

Li, F., Chong, Z. Z., & Maiese, K. (2006) · PubMed · doi:10.14670/hh-21.103 · Cited by 154

Stem Cell Research

Weissman, I. L. (2005) · JAMA · doi:10.1001/jama.294.11.1359 · Cited by 150

SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor

Rodríguez, J., Esteve, P., Weinl, C., Ruiz, J. M., Fermin, Y., Trousse, F., Dwivedy, A., Holt, C. E., & Bovolenta, P. (2005) · Nature Neuroscience · doi:10.1038/nn1547 · Cited by 151

Wnt Signaling Regulates the Invasion Capacity of Human Mesenchymal Stem Cells

Neth, P., Karow, M., Egea, V., Hoelters, J., Jochum, M., & Ries, C. (2006) · Stem Cells · doi:10.1634/stemcells.2005-0503 · Cited by 152

Tiki1 Is Required for Head Formation via Wnt Cleavage-Oxidation and Inactivation

Zhang, X., Abreu, J. G., Yokota, C., MacDonald, B. T., Singh, S. A., Coburn, K. L. A., Cheong, S.-M., Zhang, M. M., Ye, Q.-Z., Hang, H. C., et al. (2012) · Cell · doi:10.1016/j.cell.2012.04.039 · Cited by 150

DKK1 Antagonizes Wnt Signaling without Promotion of LRP6 Internalization and Degradation

Semënov, M. V., Zhang, X., & He, X. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m800014200 · Cited by 133

The role of WNT signaling in adult ovarian folliculogenesis

Gifford, J. A. H. (2015) · Reproduction · doi:10.1530/rep-14-0685 · Cited by 150

Helping Wingless take flight: how WNT proteins are secreted

Hausmann, G., Bänziger, C., & Basler, K. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2141 · Cited by 147

Canonical and non‐canonical wnts differentially affect the development potential of primary isolate of human bone marrow mesenchymal stem cells

Baksh, D., & Tuan, R. S. (2007) · Journal of Cellular Physiology · doi:10.1002/jcp.21080 · Cited by 149

Autologous liquid platelet rich fibrin: A novel drug delivery system

Miron, R. J., & Zhang, Y. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.05.021 · Cited by 159

A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities

Najdi, R., Proffitt, K. D., Sprowl-Tanio, S., Kaur, S. J., Yu, J., Covey, T. M., Virshup, D. M., & Waterman, M. L. (2012) · Differentiation · doi:10.1016/j.diff.2012.06.004 · Cited by 147

Presence of a functional receptor for GLP‐1 in osteoblastic cells, independent of the cAMP‐linked GLP‐1 receptor

Nuche‐Berenguer, B., Portal‐Núñez, S., Moreno, P., González, N., Acitores, A., López‐Herradón, A., Esbrit, P., Valverde, I., & Villanueva‐Peñacarrillo, M. L. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22243 · Cited by 146

How Wnt Signaling Affects Bone Repair by Mesenchymal Stem Cells from the Bone Marrow

Gregory, C. A., Gunn, W., Reyes, E. D., SMOLARZ, A. J., Munoz, J. R., Spees, J. L., & Prockop, D. J. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1334.010 · Cited by 146

Signalling pathways that control vertebrate haematopoietic stem cell specification

Clements, W. K., & Traver, D. J. (2013) · Nature reviews. Immunology · doi:10.1038/nri3443 · Cited by 148

Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling inXenopusaxis formation

Cha, S., Tadjuidje, E., Tao, Q., Wylie, C. C., & Heasman, J. (2008) · Development · doi:10.1242/dev.029025 · Cited by 153

Extracellular Movement of Signaling Molecules

Müller, P., & Schier, A. F. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.06.001 · Cited by 145

Activation of Wnt/β‐catenin pathway mediates growth and survival in B‐cell progenitor acute lymphoblastic leukaemia

Khan, N. I., Bradstock, K. F., & Bendall, L. J. (2007) · British Journal of Haematology · doi:10.1111/j.1365-2141.2007.06667.x · Cited by 146

Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling

Emons, G., Spitzner, M., Reineke, S., Möller, J., Auslander, N., Krämer, F., Hu, Y., Beißbarth, T., Wolff, H. A., Rave‐Fränk, M., et al. (2017) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-17-0205 · Cited by 144

Multiple Mechanisms for Wnt11-mediated Repression of the Canonical Wnt Signaling Pathway

Maye, P. F., Zheng, J., Li, L., & Wu, D. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m311724200 · Cited by 144

LRP1 Controls Intracellular Cholesterol Storage and Fatty Acid Synthesis through Modulation of Wnt Signaling

Terrand, J., Bruban, V., Zhou, L., Gong, W., El Asmar, Z., May, P., Zurhove, K., Haffner, P., Philippe, C., Woldt, E., et al. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m806538200 · Cited by 143

Neuroactive Chondroitin Sulfate Glycomimetics

Rawat, M., Gama, C. I., Matson, J. B., & Hsieh‐Wilson, L. C. (2008) · Journal of the American Chemical Society · doi:10.1021/ja709993p · Cited by 144

Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem/progenitor cells

Golestaneh, N., Beauchamp, E. M., Fallen, S., Kokkinaki, M., Üren, A., & Dym, M. (2009) · Reproduction · doi:10.1530/rep-08-0510 · Cited by 144

Targeting the Wnt pathways for therapies

Blagodatski, A. S., Poteryaev, D. A., & Katanaev, V. L. (2014) · Molecular and Cellular Therapies · doi:10.1186/2052-8426-2-28 · Cited by 147

Chemical Control of Stem Cell Fate and Developmental Potential

Lyssiotis, C. A., Lairson, L. L., Boitano, A. E., Wurdak, H., Zhu, S., & Schultz, P. G. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.201004284 · Cited by 143

Differentiation of the brain vasculature: the answer came blowing by the Wnt

Liebner, S., & Plate, K. H. (2010) · Vascular Cell · doi:10.1186/2040-2384-2-1 · Cited by 145

Wnt/β-catenin Signaling in Normal and Cancer Stem Cells

Valkenburg, K. C., Graveel, C. R., Diegel, C. R., Zhong, Z. A., & Williams, B. O. (2011) · Cancers · doi:10.3390/cancers3022050 · Cited by 144

GSK-3β inhibition/β-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons

Castelo‐Branco, G., Rawal, N., & Arenas, E. (2004) · Journal of Cell Science · doi:10.1242/jcs.01505 · Cited by 141

Structure and function of Norrin in assembly and activation of a Frizzled 4–Lrp5/6 complexPreprint

Ke, J., Harikumar, K. G., Erice, C., Chen, C., Gu, X., Wang, L., Parker, N. R., Cheng, Z., Xu, W., Williams, B. O., et al. (2013) · Genes & Development · doi:10.1101/gad.228544.113 · Cited by 141

Targeting protein lipidation in disease

Resh, M. D. (2012) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2012.01.007 · Cited by 145

Adult Bone Marrow Stem/Progenitor Cells (MSCs) Are Preconditioned by Microenvironmental "Niches" in Culture: A Two-Stage Hypothesis for Regulation of MSC Fate

Gregory, C. A., Ylöstalo, J., & Prockop, D. J. (2005) · Science s STKE · doi:10.1126/stke.2942005pe37 · Cited by 140

Histone H1 Recruitment by CHD8 Is Essential for Suppression of the Wnt–β-Catenin Signaling Pathway

Nishiyama, M., Skoultchi, A. I., & Nakayama, K. I. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.06409-11 · Cited by 141

The Soluble Wnt Receptor Frizzled8CRD-hFc Inhibits the Growth of Teratocarcinomas In vivo

DeAlmeida, V. I., Li, M., Ernst, J. A., Koeppen, H., Polakis, P. G., & Rubinfeld, B. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-0266 · Cited by 139

The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis

Pálmer, H. G., Anjos‐Afonso, F., Carmeliet, G., Takeda, H., & Watt, F. M. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001483 · Cited by 140

Glypicans shield the Wnt lipid moiety to enable signalling at a distance

McGough, I. J., Vecchia, L., Bishop, B., Malinauskas, T., Beckett, K., Joshi, D., O’Reilly, N., Siebold, C., Jones, E. Y., & Vincent, J. (2020) · Nature · doi:10.1038/s41586-020-2498-z · Cited by 140

WNT10B mutations in human obesity

Christodoulides, C., Scarda, A., Granzotto, M., Milan, G., Nora, E. D., Keogh, J. M., Pergola, G. D., Stirling, H. F., Pannacciulli, N., Sethi, J. K., et al. (2006) · Diabetologia · doi:10.1007/s00125-006-0144-4 · Cited by 139

Potential of Embryonic and Adult Stem Cells in vitro

Czyż, J., Wiese, C., Rolletschek, A., Błyszczuk, P., Cross, M. A., & Wobus, A. M. (2003) · Biological Chemistry · doi:10.1515/bc.2003.155 · Cited by 141

Structural and Functional Studies of LRP6 Ectodomain Reveal a Platform for Wnt Signaling

Chen, S., Bubeck, D., MacDonald, B. T., Liang, W., Mao, J.-H., Malinauskas, T., Llorca, Ó., Aricescu, A. R., Siebold, C., He, X., et al. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.09.007 · Cited by 136

Members of the Wnt, Fz, and Frp gene families expressed in postnatal mouse cerebral cortex

Shimogori, T., VanSant, J., Paik, E. K., & Grove, E. A. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20135 · Cited by 138

WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum

Pei, Y., Brun, S. N., Markant, S. L., Lento, W. E., Gibson, P., Taketo, M. M., Giovannini, M., Gilbertson, R. J., & Wechsler‐Reya, R. J. (2012) · Development · doi:10.1242/dev.050104 · Cited by 138

Wnt/β-Catenin Signaling Determines the Vasculogenic Fate of Postnatal Mesenchymal Stem Cells

Zhang, Z., Nör, F., Oh, M., Cucco, C., Shi, S., & Nor, J. E. (2016) · Stem Cells · doi:10.1002/stem.2334 · Cited by 138

Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of β-catenin in prostate cancer

Fiorentino, M., Zadra, G., Palescandolo, E., Fedele, G., Bailey, D., Fiore, C., Nguyen, P. L., Migita, T., Zamponi, R., Vizio, D. D., et al. (2008) · Laboratory Investigation · doi:10.1038/labinvest.2008.97 · Cited by 136

The WNT/Calcium pathway: biochemical mediators, tools and future requirements

Kühl, M. (2004) · Frontiers in bioscience · doi:10.2741/1307 · Cited by 140

Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation

Davis, E., Zou, Y.-M., & Ghosh, A. (2008) · Neural Development · doi:10.1186/1749-8104-3-32 · Cited by 151

NELL-1 in the treatment of osteoporotic bone loss

James, A. W., Shen, J., Zhang, X., Asatrian, G., Goyal, R., Kwak, J. H., Jiang, L., Bengs, B. C., Culiat, C. T., Turner, A. S., et al. (2015) · Nature Communications · doi:10.1038/ncomms8362 · Cited by 134

Wnt3a Growth Factor Induces Androgen Receptor-Mediated Transcription and Enhances Cell Growth in Human Prostate Cancer Cells

Verras, M., Brown, J. D., Li, X., Nusse, R., & Sun, Z. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-2370 · Cited by 134

The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis

Staal, F. J. T., & Sen, J. M. (2008) · European Journal of Immunology · doi:10.1002/eji.200738118 · Cited by 140

In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states

Neagu, A., van Genderen, E., Escudero, I., Verwegen, L., Kurek, D., Lehmann, J., Stel, J. M., Dirks, R. A. M., van Mierlo, G., Maas, A., et al. (2020) · Nature Cell Biology · doi:10.1038/s41556-020-0508-x · Cited by 138

A little fat ... could go a long way

Bussell, K. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1139

Sticky Proteins for Stem Cells

Kolter, T. (2003) · ChemBioChem · doi:10.1002/cbic.200300733 · Cited by 1

Constructing cellular niche properties by localized presentation of Wnt proteins on synthetic surfaces

Lowndes, M., Junyent, S., & Habib, S. J. (2017) · Nature Protocols · doi:10.1038/nprot.2017.061 · Cited by 28

Making, Exporting, and Modulating Wnts

Langton, P. F., Kakugawa, S., & Vincent, J. (2016) · Trends in Cell Biology · doi:10.1016/j.tcb.2016.05.011 · Cited by 98

A truncated Wnt7a retains full biological activity in skeletal muscle

von Maltzahn, J., Zinoviev, R. I., Chang, N. C., Bentzinger, C. F., & Rudnicki, M. A. (2013) · Nature Communications · doi:10.1038/ncomms3869 · Cited by 49