Cited by 10,728MicroRNA in disease regulationDevelopmental Biology and Gene RegulationPlant Molecular Biology Research

The DOI matches its Crossref record; 51 of the 52 references it cites were found in a registry or an index.

The functions of animal microRNAs

Ambros, Victor·2004·Nature

Open this paper in CoChat — free account

Abstract

MicroRNAs (miRNAs) are small RNAs that regulate the expression of complementary messenger RNAs. Hundreds of miRNA genes have been found in diverse animals, and many of these are phylogenetically conserved. With miRNA roles identified in developmental timing, cell death, cell proliferation, haematopoiesis and patterning of the nervous system, evidence is mounting that animal miRNAs are more numerous, and their regulatory impact more pervasive, than was previously suspected.

Integrity signals

Registry

Crossref · 10.1038/nature02871

Cites

51 of 51 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Untitled work
Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948
Self-citation
Prediction of Mammalian MicroRNA Targets
Lewis, B. P., Shih, I.-H., Jones-Rhoades, M. W., Bartel, D. P., & Burge, C. B. (2003) · Cell · doi:10.1016/s0092-8674(03)01018-3 · Cited by 5,199
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
Reinhart, B. J., Slack, F. J., Basson, M., Pasquinelli, A. E., Bettinger, J. C., Rougvie, A. E., Horvitz, H. R., & Ruvkun, G. (2000) · Nature · doi:10.1038/35002607 · Cited by 4,989
Identification of Novel Genes Coding for Small Expressed RNAs
Lagos-Quintana, M., Rauhut, R., Lendeckel, W., & Tuschl, T. (2001) · Science · doi:10.1126/science.1064921 · Cited by 4,956
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
Wightman, B., Ha, I., & Ruvkun, G. (1993) · Cell · doi:10.1016/0092-8674(93)90530-4 · Cited by 4,292
MicroRNA targets in Drosophila
Enright, A. J., John, B., Gaul, U., Tuschl, T., Sander, C., & Marks, D. S. (2003) · Genome Biology · doi:10.1186/gb-2003-5-1-r1 · Cited by 3,597
Identification of tissue-specific microRNAs from mouse
Lagos-Quintana, M., Rauhut, R., Yalcin, A., Meyer, J., Lendeckel, W., & Tuschl, T. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00809-6 · Cited by 3,355
An Abundant Class of Tiny RNAs with Probable Regulatory Roles in Caenorhabditis elegans
Lau, N. C., Lim, L. P., Weinstein, E. G., & Bartel, D. P. (2001) · Science · doi:10.1126/science.1065062 · Cited by 3,345
MicroRNAs Modulate Hematopoietic Lineage Differentiation
Chen, C.-Z., Li, L., Lodish, H. F., & Bartel, D. P. (2004) · Science · doi:10.1126/science.1091903 · Cited by 3,257

Flagged first, then by citations

Show all 52 references

1 of the 52 references couldn’t be matched to a known paper.

Sorted by citations

Items 401–500 of 1,054

Epigenetics of endometriosis
Guo, S.-W. (2009) · Molecular Human Reproduction · doi:10.1093/molehr/gap064 · Cited by 328
An alternative mode of microRNA target recognition
Chi, S. W., Hannon, G. J., & Darnell, R. B. (2012) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2230 · Cited by 328
Cutting Edge: TNF-Induced MicroRNAs Regulate TNF-Induced Expression of E-Selectin and Intercellular Adhesion Molecule-1 on Human Endothelial Cells: Feedback Control of Inflammation
Suárez, Y., Wang, C., Manes, T. D., & Pober, J. S. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0902369 · Cited by 328
The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis
Nakasa, T., Shibuya, H., Nagata, Y., Niimoto, T., & Ochi, M. (2011) · Arthritis & Rheumatism · doi:10.1002/art.30321 · Cited by 328
Retracted: Post‐transcriptional regulation of the let‐7 microRNA during neural cell specification
Wulczyn, F. G., Smirnova, L., Rybak‐Wolf, A., Brandt, C., Kwidzinski, E., Ninnemann, O., Strehle, M., Seiler, A. E. M., Schumacher, S., & Nitsch, R. (2006) · The FASEB Journal · doi:10.1096/fj.06-6130com · Cited by 328
Retracted
The silent treatment: siRNAs as small molecule drugs
Dykxhoorn, D. M., Palliser, D., & Lieberman, J. (2006) · Gene Therapy · doi:10.1038/sj.gt.3302703 · Cited by 328
MicroRNA Cluster 221-222 and Estrogen Receptor α Interactions in Breast Cancer
Leva, G. D., Gasparini, P., Piovan, C., Ngankeu, A., Garofalo, M., Taccioli, C., Iorio, M. V., Li, M., Volinia, S., Alder, H., et al. (2010) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djq102 · Cited by 328
Hepatocellular carcinoma in non-cirrhotic liver: A comprehensive review
Desai, A., Sandhu, S., Lai, J., & Sandhu, D. S. (2019) · World Journal of Hepatology · doi:10.4254/wjh.v11.i1.1 · Cited by 328
MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer
Zhang, Y., Guo, L., Li, Y., Feng, G., Teng, F., Li, W., & Zhou, Q. (2018) · Molecular Cancer · doi:10.1186/s12943-017-0753-1 · Cited by 334
Joint Genome-Wide Profiling of miRNA and mRNA Expression in Alzheimer's Disease Cortex Reveals Altered miRNA Regulation
Nunez-Iglesias, J., Liu, C.-C., Morgan, T. E., Finch, C. E., & Zhou, X. J. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008898 · Cited by 326
Frequency and fate of microRNA editing in human brain
Kawahara, Y., Megraw, M., Kreider, E., Iizasa, H., Valente, L., Hatzigeorgiou, A. G., & Nishikura, K. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn479 · Cited by 325
Integrative approaches for predicting microRNA function and prioritizing disease-related microRNA using biological interaction networks
Zeng, X., Zhang, X., & Zou, Q. (2015) · Briefings in Bioinformatics · doi:10.1093/bib/bbv033 · Cited by 325
Prediction of microRNAs Associated with Human Diseases Based on Weighted k Most Similar Neighbors
Xuan, P., Han, K., Guo, M., Guo, Y., Li, J., Ding, J., Liu, Y., Dai, Q., Li, J., Teng, Z., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070204 · Cited by 324
MicroRNAs as Potential Signatures of Environmental Exposure or Effect: A Systematic Review
Vrijens, K., Bollati, V., & Nawrot, T. S. (2015) · Environmental Health Perspectives · doi:10.1289/ehp.1408459 · Cited by 323
DNA methylomes, histone codes and miRNAs: Tying it all together
Guil, S., & Esteller, M. (2008) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2008.09.005 · Cited by 323
Reproducibility of quantitative RT-PCR array in miRNA expression profiling and comparison with microarray analysis
Chen, Y., Gelfond, J. A., McManus, L. M., & Shireman, P. K. (2009) · BMC Genomics · doi:10.1186/1471-2164-10-407 · Cited by 323
Electrochemical Biosensors for Whole Blood Analysis: Recent Progress, Challenges, and Future Perspectives
Li, S., Zhang, H., Zhu, M. Z., Kuang, Z., Li, X., Xu, F., Miao, S., Zhang, Z., Lou, X., Li, H., et al. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00759 · Cited by 324
MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte–associated antigen 4
Sonkoly, E., Janson, P., Majuri, M., Savinko, T., Fyhrquist, N., Eidsmo, L., Xu, N., Meisgen, F., Wei, T., Bradley, M., et al. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.05.045 · Cited by 322
The role of neuroimmune signaling in alcoholism
Crews, F. T., Lawrimore, C. J., Walter, T. J., & Coleman, L. G. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.01.031 · Cited by 321
Differential Regulation of Germline mRNAs in Soma and Germ Cells by Zebrafish miR-430
Mishima, Y., Giraldez, A. J., Takeda, Y., Fujiwara, T., Sakamoto, H., Schier, A. F., & Inoue, K. (2006) · Current Biology · doi:10.1016/j.cub.2006.08.086 · Cited by 321
Identification of Cellular Genes Targeted by KSHV-Encoded MicroRNAs
Samols, M. A., Skalsky, R. L., Maldonado, A. M., Riva, A., López, M. C., Baker, H. V., & Renne, R. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030065 · Cited by 319
The Guardian's Little Helper: MicroRNAs in the p53 Tumor Suppressor Network
He, X., He, L., & Hannon, G. J. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-2672 · Cited by 319
miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells
Sun, G., Ye, P., Murai, K., Lang, M., Li, S., Zhang, H., Li, W., Fu, C., Yin, J., Wang, A., et al. (2011) · Nature Communications · doi:10.1038/ncomms1532 · Cited by 317
Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway
Marcet, B., Chevalier, B., Luxardi, G., Coraux, C., Zaragosi, L., Cibois, M., Robbe-Sermesant, K., Jolly, T., Cardinaud, B., Moreilhon, C., et al. (2011) · Nature Cell Biology · doi:10.1038/ncb2241 · Cited by 317
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
Egea, J., Fabregat, I., Frapart, Y., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K. I., Knaus, U. G., López, M. G., González, G. O., et al. (2017) · Redox Biology · doi:10.1016/j.redox.2017.05.007 · Cited by 321
Aging alters tissue resident mesenchymal stem cell properties
Alt, E. U., Senst, C., Murthy, S. N., Slakey, D. P., Dupin, C. L., Chaffin, A. E., Kadowitz, P. J., & Izadpanah, R. (2012) · Stem Cell Research · doi:10.1016/j.scr.2011.11.002 · Cited by 316
MicroRNAs in lipid metabolism
Fernandez-Hernando, C. F., Suárez, Y., Rayner, K. J., & Moore, K. J. (2010) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e3283428d9d · Cited by 315
The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons
Sone, M., Hayashi, T., Tarui, H., Agata, K., Takeichi, M., & Nakagawa, S. (2007) · Journal of Cell Science · doi:10.1242/jcs.009357 · Cited by 314
Exosome and mesenchymal stem cell cross-talk in the tumor microenvironment
Whiteside, T. L. (2017) · Seminars in Immunology · doi:10.1016/j.smim.2017.12.003 · Cited by 314
Noncoding Flavivirus RNA Displays RNA Interference Suppressor Activity in Insect and Mammalian Cells
Schnettler, E., Sterken, M. G., Leung, J. Y., Metz, S., Geertsema, C., Goldbach, R. W., Vlak, J. M., Kohl, A., Khromykh, A. A., & Pijlman, G. P. (2012) · Journal of Virology · doi:10.1128/jvi.01104-12 · Cited by 313
Treating cancer with microRNA replacement therapy: A literature review
Hosseinahli, N., Aghapour, M., Duijf, P. H. G., & Baradaran, B. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26514 · Cited by 313
Transcriptome-wide miR-155 Binding Map Reveals Widespread Noncanonical MicroRNA Targeting
Loeb, G. B., Khan, A. A., Canner, D., Hiatt, J. B., Shendure, J., Darnell, R. B., Leslie, C. S., & Rudensky, A. Y. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.10.002 · Cited by 311
MicroRNA-328 Negatively Regulates the Expression of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Cancer Cells
Pan, Y.-Z., Morris, M. E., & Yu, A. (2009) · Molecular Pharmacology · doi:10.1124/mol.108.054163 · Cited by 311
MicroRNAs in Alzheimer’s Disease
Wang, M., Qin, L., & Tang, B. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00153 · Cited by 312
Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathwayPreprint
Kent, O. A., Chivukula, R. R., Mullendore, M. E., Wentzel, E. A., Feldmann, G., Lee, K. H., Liu, S., Leach, S. D., Maitra, A., & Mendell, J. T. (2010) · Genes & Development · doi:10.1101/gad.1950610 · Cited by 311
MicroRNAs 221 and 222 Bypass Quiescence and Compromise Cell Survival
Medina, R., Zaidi, S. K., Liu, C., Stein, J. L., van Wijnen, A. J., Croce, C. M., & Stein, G. S. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-6754 · Cited by 310
Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications
Ojeh, N. O., Pastar, I., Tomic‐Canic, M., & Stojadinović, O. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms161025476 · Cited by 310
The Potential of MicroRNAs as Prostate Cancer Biomarkers
Fabris, L., Ceder, Y., Chinnaiyan, A. M., Jenster, G. W., Sørensen, K. D., Tomlins, S. A., Visakorpi, T., & Călin, G. A. (2016) · European Urology · doi:10.1016/j.eururo.2015.12.054 · Cited by 310
MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism
Iliopoulos, D., Drosatos, K., Hiyama, Y., Goldberg, I. J., & Zannis, V. I. (2010) · Journal of Lipid Research · doi:10.1194/jlr.m004812 · Cited by 308
Small RNA‐mediated regulation of iPS cell generation
Li, Z., Yang, C., Nakashima, K., & Rana, T. M. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.2 · Cited by 308
A MicroRNA Expression Signature for Cervical Cancer Prognosis
Hu, X., Schwarz, J. K., Lewis, J. S., Huettner, P. C., Rader, J. S., Deasy, J. O., Grigsby, P. W., & Wang, X. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-3289 · Cited by 307
A positive feedback between p53 and miR-34 miRNAs mediates tumor suppressionPreprint
Okada, N., Lin, C., Ribeiro, M. C., Biton, A., Lai, G., He, X., Bu, P., Vogel, H. S., Jablons, D. M., Keller, A., et al. (2014) · Genes & Development · doi:10.1101/gad.233585.113 · Cited by 307
MicroRNA Detection Specificity: Recent Advances and Future Perspective
Ouyang, T., Liu, Z., Han, Z., & Ge, Q. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.8b05909 · Cited by 306
MicroRNA and drug resistance
Ma, J., Dong, C., & Ji, C. (2010) · Cancer Gene Therapy · doi:10.1038/cgt.2010.18 · Cited by 304
MicroRNA Regulation of Cardiovascular Development
Cordes, K. R., & Srivastava, D. (2009) · Circulation Research · doi:10.1161/circresaha.108.192872 · Cited by 304
Dual coding of siRNAs and miRNAs by plant transposable elements
Piriyapongsa, J., & Jordan, I. K. (2008) · RNA · doi:10.1261/rna.916708 · Cited by 303
Partition function and base pairing probabilities of RNA heterodimers
Bernhart, S. H., Tafer, H., Mückstein, U., Flamm, C., Stadler, P. F., & Hofacker, I. L. (2006) · Algorithms for Molecular Biology · doi:10.1186/1748-7188-1-3 · Cited by 302
Genome of the house fly, Musca domestica L., a global vector of diseases with adaptations to a septic environment
Scott, J. G., Warren, W. C., Beukeboom, L. W., Bopp, D., Clark, A. G., Giers, S. D., Hediger, M., Jones, A. K., Kasai, S., Leichter, C. A., et al. (2014) · Genome biology · doi:10.1186/s13059-014-0466-3 · Cited by 301
MicroRNA in TLR signaling and endotoxin tolerance
Nahid, M. A., Satoh, M., & Chan, E. K. L. (2011) · Cellular and Molecular Immunology · doi:10.1038/cmi.2011.26 · Cited by 299
The MYCN oncogene is a direct target of miR-34a
Wei, J. S., Song, Y., Durinck, S., Chen, Q.-R., Cheuk, A., Tsang, P., Zhang, Q., Thiele, C. J., Slack, A., Shohet, J. M., et al. (2008) · Oncogene · doi:10.1038/onc.2008.154 · Cited by 299
Blood–Spinal Cord Barrier in Spinal Cord Injury: A Review
Jin, L., Li, J., Wang, K., Xia, W., Zhu, Z., Wang, C., Li, X., & Liu, H. (2020) · Journal of Neurotrauma · doi:10.1089/neu.2020.7413 · Cited by 301
Human microRNA clusters: Genomic organization and expression profile in leukemia cell lines
Yu, J., Wang, F., Yang, G., Wang, F.-L., Ma, Y., Du, Z., & Zhang, J. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.07.207 · Cited by 297
RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain
NELSON, P. T., BALDWIN, D. A., KLOOSTERMAN, W. P., KAUPPINEN, S., PLASTERK, R. H. A., & MOURELATOS, Z. (2006) · RNA · doi:10.1261/rna.2258506 · Cited by 297
Advances in digital polymerase chain reaction (dPCR) and its emerging biomedical applications
Cao, L., Cui, X., Hu, J., Li, Z., Choi, J. R., Yang, Q., Lin, M., Hui, L. Y., & Xu, F. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.09.082 · Cited by 298
circHIPK3 regulates cell proliferation and migration by sponging miR-124 and regulating AQP3 expression in hepatocellular carcinoma
Chen, G., Shi, Y., Liu, M., & Sun, J. (2018) · Cell Death and Disease · doi:10.1038/s41419-017-0204-3 · Cited by 297
3′ end mRNA processing: molecular mechanisms and implications for health and disease
Danckwardt, S., Hentze, M. W., & Kulozik, A. E. (2008) · The EMBO Journal · doi:10.1038/sj.emboj.7601932 · Cited by 296
Over‐expressed microRNA‐27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation
Ji, J., Zhang, J., Huang, G., Qian, J., Wang, X., & Mei, S. (2009) · FEBS Letters · doi:10.1016/j.febslet.2009.01.034 · Cited by 295
Identification of microRNAs associated with ileal and colonic Crohnʼs disease†
Wu, F., Zhang, S., Dassopoulos, T., Harris, M. L., Bayless, T. M., Meltzer, S. J., Brant, S. R., & Kwon, J. H. (2010) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21267 · Cited by 293
miR-126 functions as a tumour suppressor in human gastric cancer
Feng, R., Chen, X., Yu, Y., Su, L., Yu, B., Li, J., Cai, Q., Yan, M., Liu, B., & Zhu, Z. (2010) · Cancer Letters · doi:10.1016/j.canlet.2010.06.004 · Cited by 293
Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1
Zhang, J., Tu, Q., Bonewald, L. F., He, X., Stein, G. S., Lian, J. B., & Chen, J. (2011) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.377 · Cited by 292
microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN
ZHANG, B. G., Li, J. F., YU, B. Q., Zhu, Z., Liu, B., & Yan, M. (2012) · Oncology Reports · doi:10.3892/or.2012.1645 · Cited by 291
Catalytic Molecular Imaging of MicroRNA in Living Cells by DNA‐Programmed Nanoparticle Disassembly
He, X., Zeng, T., Li, Z., Wang, G., & Ma, N. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201509726 · Cited by 291
miR-24–mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells
Lal, A., Pan, Y., Navarro, F., Dykxhoorn, D. M., Moreau, L. A., Meire, E., Bentwich, Z., Lieberman, J., & Chowdhury, D. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1589 · Cited by 290
Plant and animal microRNAs: similarities and differences
Millar, A. A., & Waterhouse, P. M. (2005) · Functional & Integrative Genomics · doi:10.1007/s10142-005-0145-2 · Cited by 290
miR-146a controls the resolution of T cell responses in mice
Yang, L., Boldin, M., Yu, Y. W., Liu, C. S., Ea, C.-K., Ramakrishnan, P., Taganov, K. D., Zhao, J. L., & Baltimore, D. (2012) · The Journal of Experimental Medicine · doi:10.1084/jem.20112218 · Cited by 289
Aging and the cardiac collagen matrix: Novel mediators of fibrotic remodelling
Horn, M., & Trafford, A. W. (2015) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2015.11.005 · Cited by 289
Effect of Alcohol on miR‐212 Expression in Intestinal Epithelial Cells and Its Potential Role in Alcoholic Liver Disease
Tang, Y., Banan, A., Forsyth, C. B., Fields, J. Z., Lau, C. K., Zhang, L. J., & Keshavarzian, A. (2007) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2007.00584.x · Cited by 288
Functional aspects of animal microRNAs
Williams, A. E. (2007) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-7355-9 · Cited by 288
Multiplexed Detection Methods for Profiling MicroRNA Expression in Biological Samples
Wark, A. W., Lee, H. J., & Corn, R. M. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200702450 · Cited by 287
Profiling microRNA expression with microarrays
Yin, J. Q., Zhao, R. C., & Morris, K. V. (2008) · Trends in biotechnology · doi:10.1016/j.tibtech.2007.11.007 · Cited by 287
Downregulation of microRNAs‐143 and ‐145 in B‐cell malignancies
Akao, Y., Nakagawa, Y., Kitade, Y., Kinoshita, T., & Naoe, T. (2007) · Cancer Science · doi:10.1111/j.1349-7006.2007.00618.x · Cited by 287
Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti-inflammatory action of glucocorticoids
Moschos, S. A., Williams, A. E., Perry, M. M., Birrell, M. A., Belvisi, M. G., & Lindsay, M. A. (2007) · BMC Genomics · doi:10.1186/1471-2164-8-240 · Cited by 286
MicroRNAs of the mammalian eye display distinct and overlapping tissue specificity.
Ryan, D. G., Oliveira-Fernandes, M., & Lavker, R. M. (2006) · PubMed · Cited by 285
Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice
Zhang, H., Wu, J. S., Wu, J., Fan, Q. W., Zhou, J., Wu, J., Liu, S., Zang, J., Ye, J., Xiao, M., et al. (2019) · Journal of Nanobiotechnology · doi:10.1186/s12951-019-0461-7 · Cited by 284
A Family of Human MicroRNA Genes from Miniature Inverted-Repeat Transposable Elements
Piriyapongsa, J., & Jordan, I. K. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000203 · Cited by 283
The central role of RNA in human development and cognition
Mattick, J. S. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.05.001 · Cited by 283
MicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epithelia
Yu, J., Ryan, D. G., Getsios, S., Oliveira-Fernandes, M., Fatima, A., & Lavker, R. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803992105 · Cited by 283
Abiotic stress response in plants: When post-transcriptional and post-translational regulations control transcription
Mazzucotelli, E., Mastrangelo, A. M., Crosatti, C., Guerra, D., Stanca, A. M., & Cattivelli, L. (2008) · Plant Science · doi:10.1016/j.plantsci.2008.02.005 · Cited by 283
Branched-chain Amino Acids: Catabolism in Skeletal Muscle and Implications for Muscle and Whole-body Metabolism
Mann, G., Mora, S., Madu, G., & Adegoke, O. A. J. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.702826 · Cited by 283
MicroRNAs: new players in IBD
Kalla, R., Ventham, N. T., Kennedy, N. A., Quintana, J. F., Nimmo, E. R., Buck, A. H., & Satsangi, J. (2014) · Gut · doi:10.1136/gutjnl-2014-307891 · Cited by 281
A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer
Hu, X., MacDonald, D. M., Huettner, P. C., Feng, Z., Naqa, I. E., Schwarz, J. K., Mutch, D. G., Grigsby, P. W., Powell, S. N., & Wang, X. (2009) · Gynecologic Oncology · doi:10.1016/j.ygyno.2009.05.022 · Cited by 280
Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression
Gidlöf, O., van der Brug, M., Öhman, J. N., Gilje, P., Olde, B., Wahlestedt, C., & Erlinge, D. (2013) · Blood · doi:10.1182/blood-2012-10-461798 · Cited by 280
miR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: An essential role for apoptosis
Guo, C., Pan, Q., Li, D., Sun, H., & Liu, B. (2009) · Journal of Hepatology · doi:10.1016/j.jhep.2008.11.025 · Cited by 280
Physiological cardiac remodelling in response to endurance exercise training: cellular and molecular mechanisms
Ellison, G. M., Waring, C. D., Vicinanza, C., & Torella, D. (2011) · Heart · doi:10.1136/heartjnl-2011-300639 · Cited by 280
The Developmental Timing Regulator AIN-1 Interacts with miRISCs and May Target the Argonaute Protein ALG-1 to Cytoplasmic P Bodies in C. elegans
Lei, D., Spencer, A., Morita, K., & Han, M. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.07.013 · Cited by 279
MicroRNAs Regulate CYP3A4 Expression via Direct and Indirect Targeting
Pan, Y.-Z., Gao, W., & Yu, A. (2009) · Drug Metabolism and Disposition · doi:10.1124/dmd.109.027680 · Cited by 279
Bisphenol A exposure leads to specific microRNA alterations in placental cells
Avissar-Whiting, M., Veiga, K. R., Uhl, K., Maccani, M. A., Gagne, L. A., Moen, E. L., & Marsit, C. J. (2010) · Reproductive Toxicology · doi:10.1016/j.reprotox.2010.04.004 · Cited by 278
A Role for miR-145 in Pulmonary Arterial Hypertension
Caruso, P. L., Dempsie, Y., Stevens, H., McDonald, R. A., Long, L., Lu, R., White, K., Mair, K. M., McClure, J., Southwood, M. R., et al. (2012) · Circulation Research · doi:10.1161/circresaha.112.267591 · Cited by 277
MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma
Chen, H.-C., Chen, G.-H., Chen, Y.-H., Liao, W.-L., Liu, C.-Y., Chang, K.-P., Chang, Y.-S., & Chen, S.-J. (2009) · British Journal of Cancer · doi:10.1038/sj.bjc.6604948 · Cited by 277
MicroRNA-451 Is Involved in the Self-renewal, Tumorigenicity, and Chemoresistance of Colorectal Cancer Stem Cells
Bitarte, N., Bandrés, E., Boni, V., Zárate, R., Rodriguez, J., González-Huarriz, M., López, I., Sola, J. J., Alonso, M. M., Fortes, P., et al. (2011) · Stem Cells · doi:10.1002/stem.741 · Cited by 277
MicroRNAs acting in a double-negative feedback loop to control a neuronal cell fate decision
Johnston, R. J., Chang, S., Etchberger, J. F., Ortiz, C. O., & Hobert, O. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505530102 · Cited by 276
Functional Genomic Analysis of RNA Interference in C. elegans
Kim, J. K., Gabel, H. W., Kamath, R. S., Tewari, M., Pasquinelli, A. E., Rual, J.-F. M., Kennedy, S. G., Dybbs, M., Bertin, N., Kaplan, J. M., et al. (2005) · Science · doi:10.1126/science.1109267 · Cited by 276
Gene silencing mechanisms mediated by Aubergine–piRNA complexes in Drosophila male gonad
Nishida, K. M., Saito, K., Mori, T., Kawamura, Y., Nagami-Okada, T., Inagaki, S., Siomi, H., & Siomi, M. C. (2007) · RNA · doi:10.1261/rna.744307 · Cited by 276
Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD
Tili, E., Michaille, J., Adair, B., Alder, H., Limagne, E., Taccioli, C., Ferracin, M., Delmas, D., Latruffe, N., & Croce, C. M. (2010) · Carcinogenesis · doi:10.1093/carcin/bgq143 · Cited by 275
EGBMMDA: Extreme Gradient Boosting Machine for MiRNA-Disease Association prediction
Chen, X., Li, H., Xie, D., & Zhao, Q. (2018) · Cell Death and Disease · doi:10.1038/s41419-017-0003-x · Cited by 275
MicroRNAs 143 and 145 are possible common onco-microRNAs in human cancers
Akao, Y., Nakagawa, Y., & Naoe, T. (2006) · Oncology Reports · doi:10.3892/or.16.4.845 · Cited by 274
Micro RNA ‐24 regulates cardiac fibrosis after myocardial infarction
Wang, J., Huang, W., Xu, R., Nie, Y., Cao, X., Meng, J., Xu, X., Hu, S., & Zheng, Z. (2012) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2012.01523.x · Cited by 274
The prognostic and functional role of microRNAs in acute myeloid leukemia
Marcucci, G., Mrózek, K., Radmacher, M. D., Garzon, R., & Bloomfield, C. D. (2010) · Blood · doi:10.1182/blood-2010-09-191312 · Cited by 274
Epigenetic Activation of Tumor Suppressor MicroRNAs in Human Cancer Cells
Saito, Y., & Jones, P. M. (2006) · Cell Cycle · doi:10.4161/cc.5.19.3340 · Cited by 274
The response of mammalian cells to double-stranded RNA
Gantier, M. P., & Williams, B. R. G. (2007) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2007.06.016 · Cited by 273

Authors: Ambros, V.
Affiliations: Dartmouth College (US)
Corresponding author: Ambros, Victor
ORCID: Ambros, Victor
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 2004-09
Volume: 431
Issue: 7006
Pages: 350-355
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/nature02871
OpenAlex: W2014946489
Cited by: 10,728
References: 52
Citations by year: 2026: 123 · 2025: 229 · 2024: 318 · 2023: 353 · 2022: 486 · 2021: 646 · 2020: 725 · 2019: 738 · 2018: 769 · 2017: 785 · 2016: 704 · 2015: 787 · 2014: 701 · 2013: 655 · 2012: 610
FWCI: 13.22
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature (publishedVersion)
PubMed (publishedVersion)
RePEc: Research Papers in Economics (submittedVersion)
Funders: National Institutes of Health
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
Keywords: microRNA, gene expression regulation, post-transcriptional regulation, developmental timing, cell death, cell proliferation, hematopoiesis, phylogenetic conservation, animal development
MeSH terms: Animals, Gene Expression Regulation, Multigene Family, Substrate Specificity, Genomics, MicroRNAs

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The functions of animal microRNAs

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks