The functions of animal microRNAs

Untitled work

Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948

Prediction of Mammalian MicroRNA Targets

Lewis, B. P., Shih, I.-H., Jones-Rhoades, M. W., Bartel, D. P., & Burge, C. B. (2003) · Cell · doi:10.1016/s0092-8674(03)01018-3 · Cited by 5,199

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

Reinhart, B. J., Slack, F. J., Basson, M., Pasquinelli, A. E., Bettinger, J. C., Rougvie, A. E., Horvitz, H. R., & Ruvkun, G. (2000) · Nature · doi:10.1038/35002607 · Cited by 4,989

Identification of Novel Genes Coding for Small Expressed RNAs

Lagos-Quintana, M., Rauhut, R., Lendeckel, W., & Tuschl, T. (2001) · Science · doi:10.1126/science.1064921 · Cited by 4,956

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

Wightman, B., Ha, I., & Ruvkun, G. (1993) · Cell · doi:10.1016/0092-8674(93)90530-4 · Cited by 4,292

MicroRNA targets in Drosophila

Enright, A. J., John, B., Gaul, U., Tuschl, T., Sander, C., & Marks, D. S. (2003) · Genome Biology · doi:10.1186/gb-2003-5-1-r1 · Cited by 3,597

Identification of tissue-specific microRNAs from mouse

Lagos-Quintana, M., Rauhut, R., Yalcin, A., Meyer, J., Lendeckel, W., & Tuschl, T. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00809-6 · Cited by 3,355

An Abundant Class of Tiny RNAs with Probable Regulatory Roles in Caenorhabditis elegans

Lau, N. C., Lim, L. P., Weinstein, E. G., & Bartel, D. P. (2001) · Science · doi:10.1126/science.1065062 · Cited by 3,345

MicroRNAs Modulate Hematopoietic Lineage Differentiation

Chen, C.-Z., Li, L., Lodish, H. F., & Bartel, D. P. (2004) · Science · doi:10.1126/science.1091903 · Cited by 3,257

An Extensive Class of Small RNAs in Caenorhabditis elegans

Lee, R. C., & Ambros, V. (2001) · Science · doi:10.1126/science.1065329 · Cited by 2,922

Prediction of Plant MicroRNA Targets

Jones-Rhoades, M. W., Reinhart, B. J., Lim, L. P., Burge, C. B., Bartel, B., & Bartel, D. P. (2002) · Cell · doi:10.1016/s0092-8674(02)00863-2 · Cited by 2,263

bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila

Brennecke, J., Hipfner, D. R., Stark, A., Russell, R. B., & Cohen, S. M. (2003) · Cell · doi:10.1016/s0092-8674(03)00231-9 · Cited by 2,042

MicroRNA-Directed Cleavage of HOXB8 mRNA

Yekta, S., Shih, I.-H., & Bartel, D. P. (2004) · Science · doi:10.1126/science.1097434 · Cited by 1,702

Specificity of microRNA target selection in translational repressionPreprint

Doench, J. G., & Sharp, P. A. (2004) · Genes & Development · doi:10.1101/gad.1184404 · Cited by 1,685

A microRNA in a Multiple-Turnover RNAi Enzyme Complex

Hutvágner, G., & Zamore, P. D. (2002) · Science · doi:10.1126/science.1073827 · Cited by 1,674

A uniform system for microRNA annotation

AMBROS, V., BARTEL, B., BARTEL, D. P., BURGE, C. B., CARRINGTON, J. C., CHEN, X., DREYFUSS, G., EDDY, S. R., GRIFFITHS-JONES, S., MARSHALL, M., et al. (2003) · RNA · doi:10.1261/rna.2183803 · Cited by 1,553

Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs

Bartel, D. P., & Chen, C. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1328 · Cited by 1,439

siRNAs can function as miRNAsPreprint

Doench, J. G., Petersen, C. P., & Sharp, P. A. (2003) · Genes & Development · doi:10.1101/gad.1064703 · Cited by 1,278

The microRNAs of Caenorhabditis elegans

Lim, L. P., Lau, N. C., Weinstein, E. G., Abdelhakim, A., Yekta, S., Rhoades, M. W., Burge, C. B., & Bartel, D. P. (2003) · Genes & Development · doi:10.1101/gad.1074403 · Cited by 1,259

The lin-4 Regulatory RNA Controls Developmental Timing in Caenorhabditis elegans by Blocking LIN-14 Protein Synthesis after the Initiation of Translation

Olsen, P. H., & Ambros, V. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9523 · Cited by 1,234

Vertebrate MicroRNA Genes

Lim, L. P., Glasner, M. E., Yekta, S., Burge, C. B., & Bartel, D. P. (2003) · Science · doi:10.1126/science.1080372 · Cited by 1,217

Embryonic Stem Cell-Specific MicroRNAs

Houbaviy, H. B., Murray, M. F., & Sharp, P. A. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00227-2 · Cited by 1,142

The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

Xu, P., Vernooy, S. Y., Guo, M., & Hay, B. A. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00250-1 · Cited by 1,011

A biochemical framework for RNA silencing in plantsPreprint

Tang, G., Reinhart, B. J., Bartel, D. P., & Zamore, P. D. (2003) · Genes & Development · doi:10.1101/gad.1048103 · Cited by 994

New microRNAs from mouse and human

LAGOS-QUINTANA, M., RAUHUT, R., MEYER, J., BORKHARDT, A., & TUSCHL, T. (2003) · RNA · doi:10.1261/rna.2146903 · Cited by 909

The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA

Moss, E. G., Lee, R. C., & Ambros, V. (1997) · Cell · doi:10.1016/s0092-8674(00)81906-6 · Cited by 850

Both Natural and Designed Micro RNAs Can Inhibit the Expression of Cognate mRNAs When Expressed in Human Cells

Zeng, Y., Wagner, E. J., & Cullen, B. R. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00541-5 · Cited by 839

Identification of Drosophila MicroRNA Targets

Stark, A., Brennecke, J., Russell, R. B., & Cohen, S. M. (2003) · PLoS Biology · doi:10.1371/journal.pbio.0000060 · Cited by 784

A combined computational-experimental approach predicts human microRNA targetsPreprint

Kiriakidou, M., Nelson, P. T., Kouranov, A., Fitziev, P., Bouyioukos, C., Mourelatos, Z., & Hatzigeorgiou, A. G. (2004) · Genes & Development · doi:10.1101/gad.1184704 · Cited by 774

A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans

Johnston, R. J., & Hobert, O. (2003) · Nature · doi:10.1038/nature02255 · Cited by 760

The lin-41 RBCC Gene Acts in the C. elegans Heterochronic Pathway between the let-7 Regulatory RNA and the LIN-29 Transcription Factor

Slack, F. J., Basson, M., Liu, Z., Ambros, V., Horvitz, H. R., & Ruvkun, G. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80245-2 · Cited by 751

MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

Zeng, Y., Yi, R., & Cullen, B. R. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1630797100 · Cited by 741

Computational identification of DrosophilamicroRNA genes

Lai, E. C., Tomančák, P., Williams, R. W., & Rubin, G. M. (2003) · Genome biology · doi:10.1186/gb-2003-4-7-r42 · Cited by 730

MicroRNAs and Other Tiny Endogenous RNAs in C. elegans

Ambros, V., Lee, R. C., Lavanway, A., Williams, P. T., & Jewell, D. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00287-2 · Cited by 706

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

Meister, G., Landthaler, M., Dorsett, Y., & Tuschl, T. (2004) · RNA · doi:10.1261/rna.5235104 · Cited by 626

Sequence-specific inhibition of small RNA function

Hutvágner, G., Simard, M. J., Mello, C. C., & Zamore, P. D. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020098 · Cited by 584

The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′UTRPreprint

Vella, M. C., Choi, E.-Y., Lin, S.-Y., Reinert, K. L., & Slack, F. J. (2004) · Genes & Development · doi:10.1101/gad.1165404 · Cited by 442

Two Genetic Circuits Repress the Caenorhabditis elegans Heterochronic Gene lin-28 after Translation Initiation

Seggerson, K., Tang, L., & Moss, E. G. (2002) · Developmental Biology · doi:10.1006/dbio.2001.0563 · Cited by 421

The Caenorhabditis elegans hunchback-like Gene lin-57/hbl-1 Controls Developmental Time and Is Regulated by MicroRNAs

Abrahante, J. E., Daul, A. L., Li, M., Volk, M. L., Tennessen, J. M., Miller, E. A., & Rougvie, A. E. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00127-8 · Cited by 356

MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode

Chang, S. S., Johnston, R. J., Frøkjær‐Jensen, C., Lockery, S. R., & Hobert, O. (2004) · Nature · doi:10.1038/nature02752 · Cited by 349

The C. elegans hunchback Homolog, hbl-1, Controls Temporal Patterning and Is a Probable MicroRNA Target

Lin, S.-Y., Johnson, S., Abraham, M. C., Vella, M. C., Pasquinelli, A. E., Gamberi, C., Gottlieb, E., & Slack, F. J. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00124-2 · Cited by 346

Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene

Seitz, H., Youngson, N. A., Lin, S., Dalbert, S., Paulsen, M., Bachellerie, J., Ferguson‐Smith, A. C., & Cavaillé, J. (2003) · Nature Genetics · doi:10.1038/ng1171 · Cited by 341

Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and Broad-Complex gene activity

Sempere, L. F., Sokol, N. S., Dubrovsky, E. B., Berger, E. M., & Ambros, V. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00208-2 · Cited by 330

Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites

Moss, E. G., & Tang, L. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00126-x · Cited by 328

Computational identification of microRNA targets

Rajewsky, N., & Socci, N. D. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2003.12.003 · Cited by 308

Computational and Experimental Identification of C. elegans microRNAs

Grad, Y. H., Aach, J., Hayes, G. D., Reinhart, B. J., Church, G. M., Ruvkun, G., & Kim, J. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00153-9 · Cited by 286

The bantam Gene Regulates Drosophila Growth

Hipfner, D. R., Weigmann, K., & Cohen, S. M. (2002) · Genetics · doi:10.1093/genetics/161.4.1527 · Cited by 184

A transcriptional regulatory cascade that controls left/right asymmetry in chemosensory neurons ofC. elegansPreprint

Chang, S. S., Johnston, R. J., & Hobert, O. (2003) · Genes & Development · doi:10.1101/gad.1117903 · Cited by 182

The Timing oflin-4RNA Accumulation Controls the Timing of Postembryonic Developmental Events inCaenorhabditis elegans

Feinbaum, R., & Ambros, V. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9272 · Cited by 148

Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis

Bashirullah, A., Pasquinelli, A. E., Kiger, A. A., Perrimon, N., Ruvkun, G., & Thummel, C. S. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00063-0 · Cited by 126

MicroRNA expression profiles classify human cancers

Lü, J., Getz, G. A., Miska, E. A., Alvarez-Saavedra, E., Lamb, J., Peck, D., Sweet-Cordero, A., Ebert, B. L., Mak, R. H., Ferrando, A. A., et al. (2005) · Nature · doi:10.1038/nature03702 · Cited by 9,637

Circular RNAs are a large class of animal RNAs with regulatory potency

Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., Maier, L., Mackowiak, S. D., Gregersen, L. H., Munschauer, M., et al. (2013) · Nature · doi:10.1038/nature11928 · Cited by 7,990

MicroRNA signatures in human cancers

Calin, G. A., & Croce, C. M. (2006) · Nature reviews. Cancer · doi:10.1038/nrc1997 · Cited by 7,668

Real-time quantification of microRNAs by stem-loop RT-PCR

Chen, C. (2005) · Nucleic Acids Research · doi:10.1093/nar/gni178 · Cited by 4,989

Combinatorial microRNA target predictions

Krek, A., Grün, D., Poy, M. N., Wolf, R., Rosenberg, L., Epstein, E. J., MacMenamin, P., da Piedade, I., Gunsalus, K. C., Stoffel, M., et al. (2005) · Nature Genetics · doi:10.1038/ng1536 · Cited by 4,603

Functions of MicroRNAs in Animals

Shao, R. (2005) · Yixue fenzi shengwuxue zazhi

Conservation and Evolution of microRNAs in Animals

LIANG, Y., Zhang, S., Luo, Y., & Zhang, Q. (2012) · Scientia Sinica Vitae · doi:10.1360/052011-594 · Cited by 3

Micro RNA s in Animal Development

Mansfield, J. H. (2010) · Wiley eBooks · doi:10.1002/9780470015902.a0021489 · Cited by 31

MicroRNA in cell differentiation and development

Shi, Y., & Jin, Y. (2009) · Science in China Series C Life Sciences · doi:10.1007/s11427-009-0040-5 · Cited by 69

The multitudinous role of microRNAs in various biological systems

Keerthana, R., Kumar, S., & Perumal, P. (2013) · Journal of Pharmacy Research · doi:10.1016/j.jopr.2013.02.033 · Cited by 2