The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.
Central nervous system control of food intake and body weight
Abstract
The capacity to adjust food intake in response to changing energy requirements is essential for survival. Recent progress has provided an insight into the molecular, cellular and behavioural mechanisms that link changes of body fat stores to adaptive adjustments of feeding behaviour. The physiological importance of this homeostatic control system is highlighted by the severe obesity that results from dysfunction of any of several of its key components. This new information provides a biological context within which to consider the global obesity epidemic and identifies numerous potential avenues for therapeutic intervention and future research.
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In the citing paper
“AOMs are indicated as an adjunct to lifestyle modification for individuals with a body mass index (BMI) of 27 kg/m 2 or greater with at least one weight-related complication or those with a BMI of 30 kg/m 2 or greater [16]”
From Nutritional considerations with antiobesity medications (2024) · cites this paper as [16]
In the citing paper
“This network regulates appetite, active energy expenditure, and basal metabolic rate, and it is made up of a complex network of central (e.g., cortical centers that control cognitive, visual, and “reward” cues) and peripheral (e.g., satiety and hunger hormones) signals [87,88].”
From The Pathophysiology of Gestational Diabetes Mellitus (2018) · cites this paper as [87]
In the citing paper
“Neurohormonal dysfunction has been implicated in the pathogenesis of diseases of insulin resistance, such as that present in GDM.”
From The Pathophysiology of Gestational Diabetes Mellitus (2018) · cites this paper as [87]
In the citing paper
“A dominant role of genetic factors in obesity pathogenesis has also been demonstrated in studies comparing the concordance of body weight among fraternal versus identical twins91, for example, as well as studies of adults adopted as infants compared with their biological and adoptive parents77,92.”
From Joint international consensus statement for ending stigma of obesity (2020) · cites this paper as [77]
In the citing paper
“Such mechanisms include a paradoxical decrease in appetite and increase in metabolic rate, which change adaptively in the opposite directions to those following most non-surgical weight loss77.”
From Joint international consensus statement for ending stigma of obesity (2020) · cites this paper as [77]
In the citing paper
“and they are stimulated by hunger signals [21, 22]”
From Chronic unpredictable stress induces depression-related behaviors by suppressing AgRP neuron activity (2021) · cites this paper as [21]
In the citing paper
“Leptin and insulin resistance are common in obesity and, considering their important functions in homeostatic processes, may play a role in poor appetite control [11].”
From Homeostatic and Circadian Control of Food Intake: Clinical Strategies to Prevent Overconsumption (2013) · cites this paper as [11]
In the citing paper
“In addition, these meal-related humeral signals can be modulated by the more tonic, or long-term, homeostatic signals which are influenced by body energy stores, namely leptin, insulin [11,12], and ghrelin [13].”
From Homeostatic and Circadian Control of Food Intake: Clinical Strategies to Prevent Overconsumption (2013) · cites this paper as [11]
Citations
Cites
Positional cloning of the mouse obese gene and its human homologue
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419
Central nervous system control of food intake
Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451
Self-citationGhrelin induces adiposity in rodents
Tschöp, M., Smiley, D. L., & Heiman, M. L. (2000) · Nature · doi:10.1038/35038090 · Cited by 3,949
A role for ghrelin in the central regulation of feeding
Nakazato, M., Murakami, N., Date, Y., Kojima, M., Matsuo, H., Kangawa, K., & Matsukura, S. (2001) · Nature · doi:10.1038/35051587 · Cited by 3,443
A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
Cummings, D. E., Purnell, J. Q., Frayo, R. S., Schmidova, K., Wisse, B. E., & Weigle, D. S. (2001) · Diabetes · doi:10.2337/diabetes.50.8.1714 · Cited by 2,940
Self-citationCritical nodes in signalling pathways: insights into insulin action
Taniguchi, C. M., Emanuelli, B., & Kahn, C. R. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1837 · Cited by 2,760
Ghrelin enhances appetite and increases food intake in humans
Wren, A. M., Seal, L. J., Cohen, M. A., Brynes, A. E., Frost, G. S., Murphy, K. G., Dhillo, W. S., Ghatei, M. A., & Bloom, S. R. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.12.8111 · Cited by 2,494
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
Cowley, M. A., Smart, J. L., Rubinstein, M., Cerdán, M. G., Diano, S., Horvath, T. L., Cone, R. D., & Low, M. J. (2001) · Nature · doi:10.1038/35078085 · Cited by 2,356
Gut hormone PYY3-36 physiologically inhibits food intake
Batterham, R. L., Cowley, M. A., Small, C. J., Herzog, H., Cohen, M. A., Dakin, C. L., Wren, A. M., Brynes, A. E., Low, M. J., Ghatei, M. A., et al. (2002) · Nature · doi:10.1038/nature00887 · Cited by 2,351
Plasma Ghrelin Levels after Diet-Induced Weight Loss or Gastric Bypass Surgery
Cummings, D. E., Weigle, D. S., Frayo, R. S., Breen, P. A., Marina, K., Dellinger, E. P., & Purnell, J. Q. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012908 · Cited by 2,271
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Flagged first, then by citations
Cited by
Sorted by citations
Items 801–900 of 1,007
Hunger Does Not Diminish Over Time in Mice Under Protracted Caloric Restriction
Hambly, C., Mercer, J. G., & Speakman, J. R. (2007) · Rejuvenation Research · doi:10.1089/rej.2007.0555 · Cited by 41
Salazar‐Ortiz, J., Camous, S., Briant, C., Lardic, L., Chesneau, D., & Guillaume, D. (2011) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-9-130 · Cited by 48
Borges, B. C., Antunes‐Rodrigues, J., de Castro, M., Bittencourt, J. C., Elias, C. F., & Elias, L. L. K. (2007) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.07.006 · Cited by 40
Neurotransmitters in Type 2 Diabetes and the Control of Systemic and Central Energy Balance
Al-Sayyar, A., Hammad, M. M., Williams, M. R., Al‐Onaizi, M., Abubaker, J. A., & Alzaïd, F. (2023) · Metabolites · doi:10.3390/metabo13030384 · Cited by 45
Mason, C. E., Foster‐Schubert, K. E., Imayama, I., Xiao, L., Kong, A., Campbell, K. L., Duggan, C. R., Wang, C.-Y., Alfano, C. M., Ulrich, C. M., et al. (2012) · Metabolism · doi:10.1016/j.metabol.2012.06.012 · Cited by 38
Contribution of anorexia to tissue wasting in cachexia
Molfino, A., Laviano, A., & Fanelli, F. R. (2010) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0b013e32833e4aa5 · Cited by 39
Toshinai, K., Yamaguchi, H., Kageyama, H., Matsuo, T., Koshinaka, K., Sasaki, K., Shioda, S., Minamino, N., & Nakazato, M. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00768.2009 · Cited by 39
Hopkins, M., Gibbons, C., Caudwell, P., Blundell, J. E., & Finlayson, G. (2016) · British Journal Of Nutrition · doi:10.1017/s0007114516000775 · Cited by 39
General and abdominal obesity in relation to the prevalence of irritable bowel syndrome
Akhondi, N., Montazerin, S. M., Soltani, S., Saneei, P., Keshteli, A. H., Esmaillzadeh, A., & Adibi, P. (2019) · Neurogastroenterology & Motility · doi:10.1111/nmo.13549 · Cited by 39
Lopes, A. P. F., da Cunha, I. C., Steffens, S. M., Ferraz, A., Vargas, J. C., de Lima, T. C. M., Neto, J. M., Faria, M. S., & Paschoalini, M. A. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.07.001 · Cited by 40
Morphological control of mitochondrial bioenergetics
Yoon, Y. (2015) · Frontiers in bioscience · doi:10.2741/4306 · Cited by 41
Neuroanatomical determinants of the sympathetic nerve responses evoked by leptin
Harlan, S. M., & Rahmouni, K. (2012) · Clinical Autonomic Research · doi:10.1007/s10286-012-0168-4 · Cited by 39
Glial cell line-derived neurotrophic factor protects against high-fat diet-induced obesity
Mwangi, S. M., Nezami, B. G., Obukwelu, B., Anitha, M., Marri, S., Fu, P. P., Epperson, M., Le, N., Shanmugam, M., Sitaraman, S. V., et al. (2014) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00364.2013 · Cited by 41
MECHANISMS IN ENDOCRINOLOGY: Hypothalamic inflammation and nutrition
ARAUJO, E. P. D., Moraes, J. C., Cintra, D. E., & Velloso, L. A. (2016) · European Journal of Endocrinology · doi:10.1530/eje-15-1207 · Cited by 39
Qiu, S., Wu, Q., Wang, H., Liu, D., Chen, C., Zhu, Z., Zheng, H., Yang, G., Li, L., & Yang, M. (2024) · Nature Communications · doi:10.1038/s41467-024-47684-9 · Cited by 38
Kaiyala, K. J., Morton, G. J., Thaler, J. P., Meek, T. H., Tylee, T. S., Ogimoto, K., & Wisse, B. E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041473 · Cited by 37
Self-citationBaladi, M. G., Daws, L. C., & France, C. P. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.02.005 · Cited by 39
Ghrelin and ghrelin receptor inhibitors: agents in the treatment of obesity
Soares, J., Roncon‐Albuquerque, R., & Leite-Moreira, A. F. (2008) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.12.9.1177 · Cited by 38
Montalbano, G., Mania, M., Guerrera, M. C., Abbate, F., Laurà, R., Navarra, M., Vega, J. A., Ciriaco, E., & Germanà, A. (2015) · Annals of Anatomy - Anatomischer Anzeiger · doi:10.1016/j.aanat.2015.11.003 · Cited by 38
Prebiotics Supplementation Impact on the Reinforcing and Motivational Aspect of Feeding
Delbès, A.-S., Castel, J., Denis, R., Morel, C., Quiñones, M., Everard, A., Cani, P. D., Massiéra, F., & Luquet, S. H. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00273 · Cited by 38
Roh, E., Hwang, S. Y., Kim, J. A., Lee, Y., Hong, S., Kim, N. H., Seo, J. A., Kim, S. G., Kim, N. H., Choi, K. M., et al. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00291 · Cited by 40
Loss of CTRP4 alters adiposity and food intake behaviors in obese mice
Sarver, D. C., Stewart, A. N., Rodriguez, S., Little, H. C., Aja, S. M., & Wong, G. W. (2020) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00448.2020 · Cited by 38
Insulin Resistance as a Common Link Between Current Alzheimer’s Disease Hypotheses
Alves, S. S., da Silva-Júnior, R. M. P., Servilha‐Menezes, G., Homolak, J., Šalković‐Petrišić, M., & Garcia‐Cairasco, N. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210234 · Cited by 39
Weigt, C., Hertrampf, T., Flenker, U., Hülsemann, F., Kurnaz, P., Fritzemeier, K. H., & Diel, P. R. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2015.06.002 · Cited by 38
Iwasaki, Y., Shimomura, K., Kohno, D., Dezaki, K., Ayush, E., Nakabayashi, H., Kubota, N., Kadowaki, T., Kakei, M., Nakata, M., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067198 · Cited by 38
Ries, V., Cheng, H., Baohan, A., Kareva, T., Oo, T. F., Rzhetskaya, M., Bland, R. J., During, M. J., Kholodilov, N. G., & Burke, R. E. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06101.x · Cited by 38
The odor of Osmanthus fragrans attenuates food intake
Yamamoto, T., Inui, T., & Tsuji, T. (2013) · Scientific Reports · doi:10.1038/srep01518 · Cited by 38
Macronutrients and obesity: Revisiting the calories in, calories out framework
Riera‐Crichton, D., & Tefft, N. (2014) · Economics & Human Biology · doi:10.1016/j.ehb.2014.04.002 · Cited by 42
Varga, B., Gesztelyi, R., Bombicz, M., Haines, D. D., Szabó, A. M., Kemény‐Beke, Á., Antal, M., Vecsernyés, M., Juhász, B., & Tósaki, Á. (2013) · Journal of Molecular Neuroscience · doi:10.1007/s12031-013-9998-3 · Cited by 37
Gómez, E. S., Massa, F., Bellocchio, L., Rueda‐Orozco, P. E., Ciofi, P., Cota, D., Oliet, S. H. R., Prospero-Garcia, O. E., & Marsicano, G. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.01.005 · Cited by 37
Menacho-Márquez, M., Nogueiras, R., Fabbiano, S., Sauzeau, V., Al–Massadi, O., Diéguez, C., & Bustelo, X. R. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.07.001 · Cited by 37
Cyr, N. E., Steger, J. S., Toorie, A. M., Yang, J. Z., Stuart, R. C., & Nillni, E. A. (2014) · Endocrinology · doi:10.1210/en.2014-1970 · Cited by 37
Higuchi, H., Niki, T., & Shiiya, T. (2008) · World Journal of Gastroenterology · doi:10.3748/wjg.14.6312 · Cited by 37
Halseth, A. E., Shan, K., Walsh, B., Gilder, K. M., & Fujioka, K. (2016) · Obesity · doi:10.1002/oby.21726 · Cited by 38
Nobis, S., Goichon, A., Achamrah, N., Guérin, C., Azhar, S., Chan, P., Morin, A., Bôle‐Feysot, C., do-Rego, J.-C., Vaudry, D., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-25548-9 · Cited by 38
Xie, Y., Zhou, G., Wang, C., Xu, X., & Li, C. (2018) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.8b05654 · Cited by 37
Predictors of Sexual Dysfunction in Veterans with Post-Traumatic Stress Disorder
Crepulja, M. L., Stevanović, A., Protuđer, M., Popović, B., Salopek-Žiha, D., & Vondraček, S. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8040432 · Cited by 45
Obesity, endocrine disruption and male infertility
Dutta, S., Biswas, A., & Sengupta, P. (2019) · Asian Pacific Journal of Reproduction · doi:10.4103/2305-0500.268133 · Cited by 38
Gu, L., Lin, K., Du, N., Ng, D. M., Lou, D., & Chen, P. (2020) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2020.10.018 · Cited by 37
Zhang, C., Wang, X., Su, R., He, J., Liu, S., Huang, Q., Qin, C., Zhang, M., Qin, J., & Chen, L. (2021) · Aquaculture · doi:10.1016/j.aquaculture.2021.737332 · Cited by 37
Hypothalamic Grb10 enhances leptin signalling and promotes weight loss
Liu, H., He, Y., Bai, J., Zhang, C., Zhang, F., Yang, Y., Luo, H., Yu, M., Liu, H., Tu, L., et al. (2023) · Nature Metabolism · doi:10.1038/s42255-022-00701-x · Cited by 37
Analyses of C. elegans Fat Metabolic Pathways
Barros, A. G. D. A., Liu, J., Lemieux, G. A., Mullaney, B., & Ashrafi, K. (2012) · Methods in cell biology · doi:10.1016/b978-0-12-394620-1.00013-8 · Cited by 36
Graebner, A. K., Iyer, M., & Carter, M. E. (2015) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2015.00111 · Cited by 37
Lampert, C., Arcego, D. M., Laureano, D. P., Diehl, L. A., Lima, I. F. D. C., Krolow, R., Pettenuzzo, L. F., Dalmaz, C., & Vendite, D. (2013) · Physiology & Behavior · doi:10.1016/j.physbeh.2013.05.026 · Cited by 37
Chigr, F., Rachidi, F., Segura, S., Mahaut, S., Tardivel, C., Jean, A., Najimi, M., & Moyse, E. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.10.040 · Cited by 37
Ghrelin and its therapeutic potential for cachectic patients
Ashitani, J.-I., Matsumoto, N., & Nakazato, M. (2009) · Peptides · doi:10.1016/j.peptides.2009.07.002 · Cited by 37
Guo, F., Xu, L., Gao, S., Sun, X., Li, Z., & Gong, Y. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12973 · Cited by 37
Making sense of metabolic obesity and hedonic obesity
Yu, Y. (2017) · Journal of Diabetes · doi:10.1111/1753-0407.12529 · Cited by 43
Regulation of the Motivation to Eat
Woods, S. C., & Begg, D. P. (2015) · Current topics in behavioral neurosciences · doi:10.1007/7854_2015_381 · Cited by 36
Paz-Filho, G., Volaco, A., Suplicy, H. L., Radominski, R. B., & Boguszewski, C. L. (2009) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302009000900005 · Cited by 38
NR2B subunit of the NMDA glutamate receptor regulates appetite in the parabrachial nucleus
Wu, Q., Zheng, R., Srisai, D., McKnight, G. S., & Palmiter, R. D. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1314137110 · Cited by 38
Gantulga, D., Maejima, Y., Nakata, M., & Yada, T. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.03.079 · Cited by 36
Strength Training and Physical Activity in Boys: a Randomized Trial
Meinhardt, U. J., Witassek, F., Petrò, R., Fritz, C., & Eiholzer, U. (2013) · PEDIATRICS · doi:10.1542/peds.2013-1343 · Cited by 36
Bahry, M. A., Chowdhury, V. S., Yang, H., Tran, P. V., Do, P. H., Han, G., Ikeda, H., Cockrem, J. F., & Furuse, M. (2016) · Neuropeptides · doi:10.1016/j.npep.2016.11.008 · Cited by 36
Novel hypophysiotropic AgRP2 neurons and pineal cells revealed by BAC transgenesis in zebrafish
Shainer, I., Hazak, A., Hawkins, T. A., Wilson, S. W., Cone, R. D., & Gothilf, Y. (2017) · Scientific Reports · doi:10.1038/srep44777 · Cited by 37
Cholecystokinin-like peptide mediates satiety by inhibiting sugar attraction
Guo, D., Zhang, Y., Zhang, S., Li, J., Guo, C., Pan, Y., Zhang, N., Liu, C., Jia, Y.-L., Li, C., et al. (2021) · PLoS Genetics · doi:10.1371/journal.pgen.1009724 · Cited by 36
Kwun, I., Cho, Y., Lomeda, R. R., Kwon, S.-T., Kim, Y., & Beattie, J. H. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507730763 · Cited by 36
Maolood, N., & Meister, B. (2009) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2009.01946.x · Cited by 35
Song, Y., Wu, K., Tan, X.-Y., Zhang, L.-H., Zhuo, M.-Q., Pan, Y., & Chen, Q. (2015) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2015.01.022 · Cited by 37
Cerrato, M., Carrera, O., Vazquez, R., Echevarrı́a, E., & Gutiérrez, E. (2010) · International Journal of Eating Disorders · doi:10.1002/eat.20884 · Cited by 36
Sex differences in behavioral decision-making and the modulation of shared neural circuits
Mowrey, W. R., & Portman, D. (2012) · Biology of Sex Differences · doi:10.1186/2042-6410-3-8 · Cited by 36
Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity
Caron, A., Labbé, S. M., Lanfray, D., Blanchard, P.-G., Villot, R., Roy, C., Sabatini, D. M., Richard, D., & Laplante, M. (2015) · Molecular Metabolism · doi:10.1016/j.molmet.2015.11.005 · Cited by 36
Hooper, L. E., Foster-Schubert, K. E., Weigle, D. S., Sorensen, B., Ulrich, C. M., & McTiernan, A. (2010) · Nutrition Research · doi:10.1016/j.nutres.2010.02.002 · Cited by 36
Purnell, J. Q., & le Roux, C. W. (2024) · Diabetes Obesity and Metabolism · doi:10.1111/dom.15478 · Cited by 38
Calcaterra, V., Rossi, V., Magenes, V. C., Baldassarre, P., Grazi, R., Loiodice, M., Fabiano, V., & Zuccotti, G. (2024) · Frontiers in Pediatrics · doi:10.3389/fped.2024.1368283 · Cited by 44
High-definition De Novo Sequencing of Crustacean Hyperglycemic Hormone (CHH)-family Neuropeptides
Jia, C., Hui, L., Cao, W., Lietz, C. B., Jiang, X., Chen, R., Catherman, A. D., Thomas, P. M., Ge, Y., Kelleher, N. L., et al. (2012) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m112.020537 · Cited by 37
Iemolo, A., Ferragud, A., Cottone, P., & Sabino, V. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.34 · Cited by 35
Naltrexone/Bupropion: An Investigational Combination for Weight Loss and Maintenance
Makowski, C. T., Gwinn, K. M., & Hurren, K. M. (2011) · Obesity Facts · doi:10.1159/000335352 · Cited by 37
Guturu, P., & Duchini, A. (2012) · International Journal of Hepatology · doi:10.1155/2012/212865 · Cited by 35
Butler, M. G., McGuire, A., & Manzardo, A. M. (2015) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-014-0411-0 · Cited by 39
Ito, Y., Banno, R., Hagimoto, S., Ozawa, Y., Arima, H., & Oiso, Y. (2011) · Regulatory Peptides · doi:10.1016/j.regpep.2011.11.010 · Cited by 35
Simon, J. J., Skunde, M., Sinno, M. H., Brockmeyer, T., Herpertz, S. C., Bendszus, M., Herzog, W., & Friederich, H. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00359 · Cited by 35
Scherma, M., Fattore, L., Castelli, M. P., Fratta, W., & Fadda, P. (2014) · Current Pharmaceutical Design · doi:10.2174/13816128113199990429 · Cited by 36
Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity
Ukena, K., Shikano, K., Kondo, K., Taniuchi, S., Furumitsu, M., Ochi, Y., Sasaki, T., Okamoto, S., Bentley, G. E., Kriegsfeld, L. J., et al. (2017) · eLife · doi:10.7554/elife.28527 · Cited by 36
Workeneh, B., Moore, L. W., Fong, J. N., Shypailo, R. J., Gaber, A. O., & Mitch, W. E. (2019) · Journal of Renal Nutrition · doi:10.1053/j.jrn.2019.01.009 · Cited by 36
Hypothalamic Astrocytes as a Specialized and Responsive Cell Population in Obesity
González‐García, I., & García‐Cáceres, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126176 · Cited by 35
Ventromedial hypothalamic OGT drives adipose tissue lipolysis and curbs obesity
Wang, Q., Zhang, B., Stutz, B., Liu, Z. W., Horváth, T. L., & Yang, X. (2022) · Science Advances · doi:10.1126/sciadv.abn8092 · Cited by 34
The Central Insulin System and Energy Balance
Begg, D. P., & Woods, S. C. (2011) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-24716-3_5 · Cited by 36
Adult obesity at the beginning of the 21st century: epidemiology, pathophysiology and health risk
GINTER, E., & Simko, V. (2008) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.1007/bf03657055 · Cited by 35
The role of transcriptional regulators in central control of appetite and body weight
Coppari, R., Ramadori, G., & Elmquist, J. K. (2009) · Nature Reviews Endocrinology · doi:10.1038/ncpendmet1070 · Cited by 35
Expression of Fos during sham sucrose intake in rats with central gustatory lesions
Mungarndee, S. S., Lundy, R. F., & Norgren, R. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90344.2008 · Cited by 35
Ducroc, R. A., Voisin, T., Firar, A. E., & Laburthe, M. (2007) · Diabetes · doi:10.2337/db07-0614 · Cited by 35
A closer look at the role of insulin for the regulation of male reproductive function
Oghbaei, H., Fattahi, A., Hamidian, G., Sadigh‐Eteghad, S., Ziaee, M., & Mahmoudi, J. (2020) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2020.113643 · Cited by 41
[Cells of innate and adaptive immunity in type 2 diabetes and obesity].
Guzmán‐Flores, J. M., & López-Briones, S. (2012) · PubMed · Cited by 34
Ginseng Panaxoside Rb1 Reduces Body Weight in Diet-Induced Obese Mice
Lin, N., Cai, D.-L., Jin, D., Chen, Y., & Shi, J. (2013) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-013-9688-3 · Cited by 34
Pancreastatin is an endogenous peptide that regulates glucose homeostasis
Valicherla, G. R., Hossain, Z., Mahata, S. K., & Gayen, J. R. (2013) · Physiological Genomics · doi:10.1152/physiolgenomics.00131.2013 · Cited by 34
Ansari, A., Bose, S., Yadav, M., Wang, J., Song, Y.-K., Ko, S., & Kim, H. (2016) · Molecules · doi:10.3390/molecules21111522 · Cited by 36
Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time
Revêchon, G., Viceconte, N., McKenna, T., Sola-Carvajal, A., Vrtačnik, P., Stenvinkel, P., Lundgren, T., Hultenby, K. R., Franco, I., & Eriksson, M. (2017) · Scientific Reports · doi:10.1038/s41598-017-04492-0 · Cited by 34
Prenatal Steroids and Metabolic Dysfunction: Lessons from Sheep
Cardoso, R. C., & Padmanabhan, V. (2018) · Annual Review of Animal Biosciences · doi:10.1146/annurev-animal-020518-115154 · Cited by 34
GPCRs in Autocrine and Paracrine Regulations
Tse, L. H., & Wong, Y. H. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00428 · Cited by 34
Li, C., Xu, J.-J., Hu, H., Shi, C.-Y., Yu, C., Sheng, J., Wu, Y., & Huang, H. (2020) · Molecular Metabolism · doi:10.1016/j.molmet.2020.101135 · Cited by 33
Roth, C. L., & Sathyanarayana, S. (2012) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-012-9212-x · Cited by 35
Somatostatin is involved in anorexia in mice fed a valine-deficient diet
Nakahara, K., Takata, S., Ishii, A., Nagao, K., Bannai, M., Takahashi, M., & Murakami, N. (2011) · Amino Acids · doi:10.1007/s00726-011-0836-z · Cited by 34
Pang, Z. P., & Han, W. (2012) · Bioscience Reports · doi:10.1042/bsr20120026 · Cited by 34
Hoch, T., Kreitz, S., Gaffling, S., Pischetsrieder, M., & Heß, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055354 · Cited by 35
Genetic Variation and Effects on Human Eating Behavior
de Krom, M., Bauer, F., Collier, D. A., Adan, R. A. H., & la Fleur, S. E. (2009) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-080508-141124 · Cited by 34
AMPK in the central nervous system: physiological roles and pathological implications
Segatto, M., Rosso, P., Fioramonti, M., Fracassi, A., Marangoni, M., Taglietti, V., & Siteni, S. (2016) · Research and Reports in Biology · doi:10.2147/rrb.s90858 · Cited by 35
Bae, J. H., Choi, H. J., Cho, K. I. K., Kim, L. K., Kwon, J. S., & Cho, Y. M. (2020) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2019.0018 · Cited by 33
The endocrine control of energy homeostasis in chickens
Song, Z., Everaert, N., Wang, Y., Decuypere, E. M. P., & Buyse, J. G. (2013) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2013.05.006 · Cited by 33
Cao, Y., Nakata, M., Okamoto, S., Takano, E., Yada, T., Minokoshi, Y., Hirata, Y., Nakajima, K., Iskandar, K., Hayashi, Y., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018324 · Cited by 33
Self-citation
Metadata
- Authors
- Morton, G. J., Cummings, D. E., Baskin, D. G., Barsh, G. S., & Schwartz, M. W.
- Affiliations
- University of Washington (US)
- Stanford Medicine (US)
- Corresponding author
- Schwartz, M. W.
- Venue
- Nature
- Published
- 2006-09
- Volume
- 443
- Issue
- 7109
- Pages
- 289-295
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2079395662
- Cited by
- 2,503
- References
- 76
- Citations by year
- 2026: 66 · 2025: 79 · 2024: 75 · 2023: 84 · 2022: 107 · 2021: 123 · 2020: 115 · 2019: 118 · 2018: 141 · 2017: 164 · 2016: 161 · 2015: 150 · 2014: 157 · 2013: 182 · 2012: 172
- FWCI
- 10.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- M.J. Murdock Charitable Trust
- National Institutes of Health
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Keywords
- food intake regulation, weight management, energy homeostasis, central nervous system, obesity, leptin, satiety, feeding behaviour, body fat stores, anti-obesity drugs, neuronal receptors
- MeSH terms
- Adipose Tissue, Body Weight, Central Nervous System, Feeding Behavior, Neuronal Plasticity, Satiety Response
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