Rare chromosomal deletions and duplications increase risk of schizophrenia

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Items 101–166 of 166

1. Glutamatergic Synaptic Dysregulation in Schizophrenia: Therapeutic Implications
   Coyle, Joseph T., Basu, Alo, Benneyworth, Michael, Balu, Darrick, Konopaske, Glenn · 2012 · Handbook of Experimental Pharmacology
2. Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS Results
   Wray, Naomi R., Purcell, Shaun M., Visscher, Peter M. · 2011 · PLoS Biology
3. Analysis of Intellectual Disability Copy Number Variants for Association With Schizophrenia
   Rees, Elliott, Kendall, Kimberley, Pardiñas, Antonio F., Legge, Sophie E., Pocklington, Andrew, Escott-Price, Valentina, MacCabe, James H., Collier, David A., Holmans, Peter, O’Donovan, Michael C. et al. · 2016 · JAMA Psychiatry
4. CNVs in neuropsychiatric disorders
   Kirov, George · 2015 · Human Molecular Genetics
5. Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental involvement in 15q11‐q13 duplication autism spectrum disorder
   Mitchell, Michelle M., Woods, Rima, Chi, Lai‐Har, Schmidt, Rebecca J., Pessah, Isaac N., Kostyniak, Paul J., LaSalle, Janine M. · 2012 · Environmental and Molecular Mutagenesis
6. Copy number variations associated with autism spectrum disorders contribute to a spectrum of neurodevelopmental disorders
   Rosenfeld, Jill A., Ballif, Blake C., Torchia, Beth S., Sahoo, Trilochan, Ravnan, J. Britt, Schultz, Roger, Lamb, Allen, Bejjani, Bassem A., Shaffer, Lisa G. · 2010 · Genetics in Medicine
7. The genetics of neurodevelopmental disease
   Mitchell, Kevin J · 2011 · Current Opinion in Neurobiology
8. Spatiotemporal 16p11.2 protein network implicates cortical late mid-fetal brain development and KCTD13-Cul3-RhoA pathway in psychiatric diseases
   Lin, Guan Ning, Corominas, Roser, Lemmens, Irma, Yang, Xinping, Tavernier, Jan, Hill, David E., Vidal, Marc, Sebat, Jonathan, Iakoucheva, Lilia M. · 2015 · Neuron
9. Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia
   Pidsley, Ruth, Viana, Joana, Hannon, Eilis, Spiers, Helen, Troakes, Claire, Al-Saraj, Safa, Mechawar, Naguib, Turecki, Gustavo, Schalkwyk, Leonard C, Bray, Nicholas J et al. · 2014 · Genome biology
10. Using large clinical data sets to infer pathogenicity for rare copy number variants in autism cohorts
    Moreno-De-Luca, D, Sanders, S J, Willsey, A J, Mulle, J G, Lowe, J K, Geschwind, D H, State, M W, Martin, C L, Ledbetter, D H · 2013 · Molecular Psychiatry
11. Male-biased autosomal effect of 16p13.11 copy number variation in neurodevelopmental disorders
    Tropeano, Maria, Ahn, Joo Wook, Dobson, Richard J. B., Breen, Gerome, Rucker, James, Dixit, Abhishek, Pal, Deb K., McGuffin, Peter, Farmer, Anne, White, Peter S. et al. · 2013 · PLoS ONE
12. A systematic review and meta‐analysis of the fertility of patients with schizophrenia and their unaffected relatives
    Bundy, H., Stahl, D., MacCabe, J. H. · 2011 · Acta Psychiatrica Scandinavica
13. Delineation of 15q13.3 microdeletions.
    Masurel‐Paulet, A, Andrieux, J, Callier, P, Cuisset, JM, Le Caignec, C, Holder, M, Thauvin‐Robinet, C, Doray, B, Flori, E, Alex‐Cordier, MP et al. · 2010 · Clinical Genetics
14. Regulation of NMDA glutamate receptor functions by the GluN2 subunits
    Vieira, Marta, Yong, Xuan Ling Hilary, Roche, Katherine W., Anggono, Victor · 2020 · Journal of Neurochemistry
15. Singleton deletions throughout the genome increase risk of bipolar disorder
    Zhang, D, Cheng, L, Qian, Y, Alliey-Rodriguez, N, Kelsoe, J R, Greenwood, T, Nievergelt, C, Barrett, T B, McKinney, R, Schork, N et al. · 2009 · Molecular Psychiatry
16. DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia
    Hannon, Eilis, Dempster, Emma L, Mansell, Georgina, Burrage, Joe, Bass, Nick, Bohlken, Marc M, Corvin, Aiden, Curtis, Charles J, Dempster, David, Di Forti, Marta et al. · 2021 · eLife
17. Derepression of a Neuronal Inhibitor due to miRNA Dysregulation in a Schizophrenia-Related Microdeletion
    Xu, Bin, Hsu, Pei-Ken, Stark, Kimberly L., Karayiorgou, Maria, Gogos, Joseph A. · 2013 · Cell
18. Copy number variation in obsessive-compulsive disorder and tourette syndrome: A cross-disorder study
    McGrath, Lauren M., Yu, Dongmei, Marshall, Christian, Davis, Lea K., Thiruvahindrapuram, Bhooma, Li, Bingbin, Cappi, Carolina, Gerber, Gloria, Wolf, Aaron, Schroeder, Frederick A. et al. · 2014 · Journal of the American Academy of Child & Adolescent Psychiatry
19. Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function
    Raychaudhuri, Soumya, Korn, Joshua M., McCarroll, Steven A., The International Schizophrenia Consortium, Altshuler, David, Sklar, Pamela, Purcell, Shaun, Daly, Mark J. · 2010 · PLoS Genetics
20. Association of Rare Copy Number Variants With Risk of Depression
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21. Common alleles contribute to schizophrenia in CNV carriers
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22. Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses
    Visscher, P M, Goddard, M E, Derks, E M, Wray, N R · 2012 · Molecular Psychiatry
23. Structures and molecular mechanisms for common 15q13.3 microduplications involving CHRNA7: benign or pathological?
    Szafranski, Przemyslaw, Schaaf, Christian P., Person, Richard E., Gibson, Ian B., Xia, Zhilian, Mahadevan, Sangeetha, Wiszniewska, Joanna, Bacino, Carlos A., Lalani, Seema, Potocki, Lorraine et al. · 2010 · Human Mutation
24. A method for rapid, targeted CNV genotyping identifies rare variants associated with neurocognitive disease
    Mefford, Heather C., Cooper, Gregory M., Zerr, Troy, Smith, Joshua D., Baker, Carl, Shafer, Neil, Thorland, Erik C., Skinner, Cindy, Schwartz, Charles E., Nickerson, Deborah A. et al. · 2009 · Genome Research
25. Perinatal Phosphatidylcholine Supplementation and Early Childhood Behavior Problems: Evidence for <i>CHRNA7</i> Moderation
    Ross, Randal G., Hunter, Sharon K., Hoffman, M. Camille, McCarthy, Lizbeth, Chambers, Betsey M., Law, Amanda J., Leonard, Sherry, Zerbe, Gary O., Freedman, Robert · 2016 · American Journal of Psychiatry
26. Copy number variants of schizophrenia susceptibility loci are associated with a spectrum of speech and developmental delays and behavior problems
    Sahoo, Trilochan, Theisen, Aaron, Rosenfeld, Jill A., Lamb, Allen N., Ravnan, J. Britt, Schultz, Roger A., Torchia, Beth S., Neill, Nicholas, Casci, Ian, Bejjani, Bassem A. et al. · 2011 · Genetics in Medicine
27. Molecular and clinical characterization of 25 individuals with exonic deletions of <i>NRXN1</i> and comprehensive review of the literature
    Béna, Frédérique, Bruno, Damien L., Eriksson, Mats, van Ravenswaaij‐Arts, Conny, Stark, Zornitza, Dijkhuizen, Trijnie, Gerkes, Erica, Gimelli, Stefania, Ganesamoorthy, Devika, Thuresson, Ann Charlotte et al. · 2013 · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
28. Maternally Derived Microduplications at 15q11-q13: Implication of Imprinted Genes in Psychotic Illness
    Ingason, Andrés, Kirov, George, Giegling, Ina, Hansen, Thomas, Isles, Anthony R., Jakobsen, Klaus D., Kristinsson, Kari T., le Roux, Louise, Gustafsson, Omar, Craddock, Nick et al. · 2011 · American Journal of Psychiatry
29. Common variant at 16p11.2 conferring risk of psychosis
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30. Is autism spectrum disorder common in schizophrenia?
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31. Schizophrenia Genetics: Where Next?
    Kim, Y., Zerwas, S., Trace, S. E., Sullivan, P. F. · 2011 · Schizophrenia Bulletin
32. The Role of DNA Copy Number Variation in Schizophrenia
    Tam, Gloria W.C., Redon, Richard, Carter, Nigel P., Grant, Seth G.N. · 2009 · Biological Psychiatry
33. A neurogenetic model for the study of schizophrenia spectrum disorders: the International 22q11.2 Deletion Syndrome Brain Behavior Consortium
    Gur, R E, Bassett, A S, McDonald-McGinn, D M, Bearden, C E, Chow, E, Emanuel, B S, Owen, M, Swillen, A, Van den Bree, M, Vermeesch, J et al. · 2017 · Molecular Psychiatry
34. Evolving Role of MeCP2 in Rett syndrome and Autism
    LaSalle, Janine M, Yasui, Dag H · 2009 · Epigenomics
35. A Population Genetic Approach to Mapping Neurological Disorder Genes Using Deep Resequencing
    Myers, Rachel A., Casals, Ferran, Gauthier, Julie, Hamdan, Fadi F., Keebler, Jon, Boyko, Adam R., Bustamante, Carlos D., Piton, Amelie M., Spiegelman, Dan, Henrion, Edouard et al. · 2011 · PLoS Genetics
36. De Novo Rates and Selection of Schizophrenia-Associated Copy Number Variants
    Rees, Elliott, Moskvina, Valentina, Owen, Michael J., O'Donovan, Michael C., Kirov, George · 2011 · Biological Psychiatry
37. Orchestration of Neurodevelopmental Programs by RBFOX1
    Bill, Brent R., Lowe, Jennifer K., DyBuncio, Christina T., Fogel, Brent L. · 2013 · International Review of Neurobiology
38. Association of common copy number variants at the glutathione S-transferase genes and rare novel genomic changes with schizophrenia
    Rodríguez-Santiago, B, Brunet, A, Sobrino, B, Serra-Juhé, C, Flores, R, Armengol, Ll, Vilella, E, Gabau, E, Guitart, M, Guillamat, R et al. · 2010 · Molecular Psychiatry
39. Quantitative Proteomic and Genetic Analyses of the Schizophrenia Susceptibility Factor Dysbindin Identify Novel Roles of the Biogenesis of Lysosome-Related Organelles Complex 1
    Gokhale, Avanti, Larimore, Jennifer, Werner, Erica, So, Lomon, Moreno-De-Luca, Andres, Lese-Martin, Christa, Lupashin, Vladimir V., Smith, Yoland, Faundez, Victor · 2012 · The Journal of Neuroscience
40. Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder
    Priebe, L, Degenhardt, F A, Herms, S, Haenisch, B, Mattheisen, M, Nieratschker, V, Weingarten, M, Witt, S, Breuer, R, Paul, T et al. · 2012 · Molecular Psychiatry
41. The current state of play on the molecular genetics of depression
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42. Reversal of dendritic phenotypes in 16p11.2 microduplication mouse model neurons by pharmacological targeting of a network hub
    Blizinsky, Katherine D., Diaz-Castro, Blanca, Forrest, Marc P., Schürmann, Britta, Bach, Anthony P., Martin-de-Saavedra, Maria Dolores, Wang, Lei, Csernansky, John G., Duan, Jubao, Penzes, Peter · 2016 · Proceedings of the National Academy of Sciences
43. Copy number variations and cancer susceptibility
    Shlien, Adam, Malkin, David · 2010 · Current Opinion in Oncology · Retracted
44. Sex-differential DNA methylation and associated regulation networks in human brain implicated in the sex-biased risks of psychiatric disorders
    Xia, Yan, Dai, Rujia, Wang, Kangli, Jiao, Chuan, Zhang, Chunling, Xu, Yuchen, Li, Honglei, Jing, Xi, Chen, Yu, Jiang, Yi et al. · 2021 · Molecular Psychiatry
45. Genome-wide Analysis of the Role of Copy Number Variation in Schizophrenia Risk in Chinese
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46. Genome-wide analysis shows increased frequency of copy number variation deletions in Dutch schizophrenia patients
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47. Phenotypic spectrum of <i>NRXN1</i> mono‐ and bi‐allelic deficiency: A systematic review
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48. Genomic Analysis of Mental Illness: A Changing Landscape
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49. Autism spectrum disorder, developmental and psychiatric features in 16p11.2 duplication
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50. Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder
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51. The role of copy number variation in schizophrenia
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52. Genome-wide association analysis of copy number variation in recurrent depressive disorder
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53. Evaluation of an approximation method for assessment of overall significance of multiple‐dependent tests in a genomewide association study
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54. Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample
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55. An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis
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56. Schizophrenia is a later‐onset feature of<i><scp>PCDH</scp>19</i>Girls Clustering Epilepsy
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57. Genetic Differences between Five European Populations
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58. Diminished cerebral inhibition in neonates associated with risk factors for schizophrenia: parental psychosis, maternal depression, and nicotine use
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59. Rare and common variants at 16p11.2 are associated with schizophrenia
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60. Genetics of Autism Spectrum Disorders
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61. Genome-wide association analysis identifies common variants influencing infant brain volumes
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63. Multiple conserved regulatory domains promote Fezf2 expression in the developing cerebral cortex
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64. Functional studies and rare variant screening of SLC1A1/EAAC1 in males with obsessive–compulsive disorder
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65. Using hiPSCs to model neuropsychiatric copy number variations (CNVs) has potential to reveal underlying disease mechanisms
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66. <i>CHRNA7</i> Deletions are Enriched in Risperidone-Treated Children and Adolescents
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