Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

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Items 101–130 of 130

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2. The Tumor Microenvironment: Characterization, Redox Considerations, and Novel Approaches for Reactive Oxygen Species-Targeted Gene Therapy
   Policastro, Lucia Laura, Ibañez, Irene Laura, Notcovich, Cintia, Duran, Hebe Alicia, Podhajcer, Osvaldo Luis · 2013 · Antioxidants & Redox Signaling
3. The regulation of cancer cell death and metabolism by extracellular matrix attachment
   Buchheit, Cassandra L., Rayavarapu, Raju R., Schafer, Zachary T. · 2012 · Seminars in Cell & Developmental Biology
4. Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy
   Zhu, Bo, Tang, Liming, Chen, Shuyang, Yin, Chengqian, Peng, Shiguang, Li, Xin, Liu, Tongzheng, Liu, Wei, Han, Changpeng, Stawski, Lukasz et al. · 2018 · Oncogene
5. Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma
   Best, Sarah A., Ding, Sheryl, Kersbergen, Ariena, Dong, Xueyi, Song, Ji-Ying, Xie, Yi, Reljic, Boris, Li, Kaiming, Vince, James E., Rathi, Vivek et al. · 2019 · Nature Communications
6. Cellular senescence in gastrointestinal diseases: from pathogenesis to therapeutics
   Frey, Nina, Venturelli, Sascha, Zender, Lars, Bitzer, Michael · 2018 · Nature Reviews Gastroenterology & Hepatology
7. LKB1 Loss Induces Characteristic Patterns of Gene Expression in Human Tumors Associated with NRF2 Activation and Attenuation of PI3K-AKT
   Kaufman, Jacob M., Amann, Joseph M., Park, Kyungho, Arasada, Rajeswara Rao, Li, Haotian, Shyr, Yu, Carbone, David P. · 2014 · Journal of Thoracic Oncology
8. Synthetic Lethal Vulnerabilities in KRAS-Mutant Cancers
   Aguirre, Andrew J., Hahn, William C. · 2018 · Cold Spring Harbor Perspectives in Medicine
9. KRas, ROS and the initiation of pancreatic cancer
   Storz, Peter · 2017 · Small GTPases
10. NRF2 immunolocalization in human breast cancer patients as a prognostic factor
    Onodera, Yoshiaki, Motohashi, Hozumi, Takagi, Kiyoshi, Miki, Yasuhiro, Shibahara, Yukiko, Watanabe, Mika, Ishida, Takanori, Hirakawa, Hisashi, Sasano, Hironobu, Yamamoto, Masayuki et al. · 2014 · Endocrine-Related Cancer
11. Nrf2 overexpression is associated with P-glycoprotein upregulation in gastric cancer
    Jeddi, Farhad, Soozangar, Narges, Sadeghi, Mohammad Reza, Somi, Mohammad Hossein, Shirmohamadi, Masoud, Eftekhar-Sadat, Amir-Taher, Samadi, Nasser · 2018 · Biomedicine & Pharmacotherapy
12. Metabolism during ECM Detachment: Achilles Heel of Cancer Cells?
    Mason, Joshua A., Hagel, Kimberly R., Hawk, Mark A., Schafer, Zachary T. · 2017 · Trends in Cancer
13. Rare codons capacitate Kras-driven de novo tumorigenesis
    Pershing, Nicole L.K., Lampson, Benjamin L., Belsky, Jason A., Kaltenbrun, Erin, MacAlpine, David M., Counter, Christopher M. · 2015 · Journal of Clinical Investigation
14. Identification of Withaferin A as a Potential Candidate for Anti-Cancer Therapy in Non-Small Cell Lung Cancer
    Hsu, Jade H.-M., Chang, Peter M.-H., Cheng, Tai-Shan, Kuo, Yu-Lun, Wu, Alexander T.-H., Tran, Thu-Ha, Yang, Yun-Hsuan, Chen, Jing-Ming, Tsai, Yu-Chen, Chu, Yeh-Shiu et al. · 2019 · Cancers
15. Sestrin2 Protein Positively Regulates AKT Enzyme Signaling and Survival in Human Squamous Cell Carcinoma and Melanoma Cells
    Zhao, Baozhong, Shah, Palak, Budanov, Andrei V., Qiang, Lei, Ming, Mei, Aplin, Andrew, Sims, Diane M., He, Yu-Ying · 2014 · Journal of Biological Chemistry
16. Identification of mutant K-Ras-dependent phenotypes using a panel of isogenic cell lines
    Vartanian, Steffan, Bentley, Carolyn, Brauer, Matthew J., Li, Li, Shirasawa, Senji, Sasazuki, Takehiko, Kim, Jung-Sik, Haverty, Pete, Stawiski, Eric, Modrusan, Zora et al. · 2013 · Journal of Biological Chemistry
17. Cell senescence as both a dynamic and a static phenotype
    Young, Andrew R. J., Narita, Masako, Narita, Masashi · 2013 · Methods in Molecular Biology
18. Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression
    DeBlasi, Janine M., Falzone, Aimee, Caldwell, Samantha, Prieto-Farigua, Nicolas, Prigge, Justin R., Schmidt, Edward E., Chio, Iok In Christine, Karreth, Florian A., DeNicola, Gina M. · 2023 · Cancer Research
19. SLC7A11 Is a Superior Determinant of APR-246 (Eprenetapopt) Response than TP53 Mutation Status
    Fujihara, Kenji M., Corrales Benitez, Mariana, Cabalag, Carlos S., Zhang, Bonnie Z., Ko, Hyun S., Liu, David S., Simpson, Kaylene J., Haupt, Ygal, Lipton, Lara, Haupt, Sue et al. · 2021 · Molecular Cancer Therapeutics
20. Inhibition of NRF2 enhances the acute myeloid leukemia cell death induced by venetoclax via the ferroptosis pathway
    Yu, Xibao, Wang, Yan, Tan, Jiaxiong, Li, Yuchen, Yang, Pengyue, Liu, Xuan, Lai, Jing, Zhang, Yue, Cai, Letong, Gu, Yinfeng et al. · 2024 · Cell Death Discovery
21. NRF2 inhibition represses ErbB2 signaling in ovarian carcinoma cells: Implications for tumor growth retardation and docetaxel sensitivity
    Manandhar, Sarala, Choi, Bo-hyun, Jung, Kyeong-Ah, Ryoo, In-geun, Song, Mingu, Kang, Su Jin, Choi, Han-Gon, Kim, Jung-Ae, Park, Pil-Hoon, Kwak, Mi-Kyoung · 2012 · Free Radical Biology and Medicine
22. The indirect antioxidant sulforaphane protects against thiopurine-mediated photooxidative stress
    Benedict, A. L., Knatko, E. V., Dinkova-Kostova, A. T. · 2012 · Carcinogenesis
23. NO•/RUNX3/kynurenine metabolic signaling enhances disease aggressiveness in pancreatic cancer
    Wang, Limin, Tang, Wei, Yang, Shouhui, He, Peijun, Wang, Jian, Gaedcke, Jochen, Ströbel, Philipp, Azizian, Azadeh, Ried, Thomas, Gaida, Matthias M. et al. · 2020 · International Journal of Cancer
24. KRAS Mutation Dictates the Cancer Immune Environment in Pancreatic Ductal Adenocarcinoma and Other Adenocarcinomas
    Gu, Meichen, Gao, Yanli, Chang, Pengyu · 2021 · Cancers
25. Pentose conversions support the tumorigenesis of pancreatic cancer distant metastases
    Bechard, Matthew E., Word, Anna E., Tran, Amanda V., Liu, Xiaojing, Locasale, Jason W., McDonald, Oliver G. · 2018 · Oncogene
26. Paradoxical Role of AT-rich Interactive Domain 1A in Restraining Pancreatic Carcinogenesis
    Ferri-Borgogno, Sammy, Barui, Sugata, McGee, Amberly M., Griffiths, Tamara, Singh, Pankaj K., Piett, Cortt G., Ghosh, Bidyut, Bhattacharyya, Sanchari, Singhi, Aatur, Pradhan, Kith et al. · 2020 · Cancers
27. Exploring the cytoprotective role of mesenchymal stem Cell-Derived exosomes in chronic liver Fibrosis: Insights into the Nrf2/Keap1/p62 signaling pathway
    Al Saihati, Hajir A., Badr, Omnia A., Dessouky, Arigue A., Mostafa, Ola, Samir Farid, Ayman, Aborayah, Nashwa H, Abdullah Aljasir, Mohammad, Baioumy, Bodour, Mahmoud Taha, Neama, El-Sherbiny, Mohamed et al. · 2024 · International Immunopharmacology
28. The complex role of NRF2 in cancer: A genomic view
    Praslicka, Brandon John, Kerins, Michael John, Ooi, Aikseng · 2016 · Current Opinion in Toxicology
29. RETRACTED: Identification of Redox-Sensitive Transcription Factors as Markers of Malignant Pleural Mesothelioma
    Schiavello, Martina, Gazzano, Elena, Bergandi, Loredana, Silvagno, Francesca, Libener, Roberta, Riganti, Chiara, Aldieri, Elisabetta · 2021 · Cancers · Retracted
30. Translatome-based classification reveals a dual metabolic dependency of a new tumor subtype of pancreatic cancer
    Shin, Sauyeun, Nicolle, Remy, Jean, Christine, Samain, Remi, Ayadi, Mira, Raffenne, Jerome, Brunel, Alexia, Solorzano, Jacobo, Neuzillet, Cindy, Joffre, Carine et al. · 2020