Local generation of glia is a major astrocyte source in postnatal cortex

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

Madisen, L., Zwingman, T. A., Sunkin, S. M., Oh, S. W., Zariwala, H. A., Gu, H., Ng, L. L., Palmiter, R. D., Hawrylycz, M. J., Jones, A. R., et al. (2010) · Nature Neuroscience · doi:10.1038/nn.2467 · Cited by 6,907 · see citing works

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898 · see citing works

The Glial Nature of Embryonic and Adult Neural Stem Cells

Kriegstein, A., & Alvarez-Buylla, A. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135600 · Cited by 2,475 · see citing works

Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain

Azevedo, F. A. C., Carvalho, L. R. B., Grinberg, L. T., Farfel, J. M., Ferretti, R. E. L., Leite, R. E. P., Filho, W. J., Lent, R., & Herculano‐Houzel, S. (2009) · Journal of Comparative Neurology · doi:10.1002/cne.21974 · Cited by 2,337 · see citing works

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

Sakaue-Sawano, A., Kurokawa, H., Morimura, T., Hanyu, A., Hama, H., Osawa, H., Kashiwagi, S., Fukami, K., Miyata, T., Miyoshi, H., et al. (2008) · Cell · doi:10.1016/j.cell.2007.12.033 · Cited by 2,123 · see citing works

Cell death and control of cell survival in the oligodendrocyte lineage

Barres, B. A., Hart, I. K., Coles, H. S. R., Burne, J. F., Voyvodic, J. T., Richardson, W. D., & Raff, M. C. (1992) · Cell · doi:10.1016/0092-8674(92)90531-g · Cited by 1,345 · see citing works

Astrocyte-mediated control of cerebral blood flow

Takano, T., Tian, G.-F., Peng, W., Lou, N., Libionka, W., Han, X., & Nedergaard, M. (2005) · Nature Neuroscience · doi:10.1038/nn1623 · Cited by 1,137 · see citing works

Epidemiology and molecular pathology of glioma

Schwartzbaum, J., Fisher, J. L., Aldape, K., & Wrensch, M. (2006) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0289 · Cited by 951 · see citing works

Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission

Rouach, N., Koulakoff, A., Abudara, V., Willecke, K., & Giaume, C. (2008) · Science · doi:10.1126/science.1164022 · Cited by 861 · see citing works

Mosaic Organization of Neural Stem Cells in the Adult Brain

Merkle, F. T., Mirzadeh, Z., & Álvarez-Buylla, A. (2007) · Science · doi:10.1126/science.1144914 · Cited by 821 · see citing works

In Vivo Fate Analysis Reveals the Multipotent and Self-Renewal Capacities of Sox2+ Neural Stem Cells in the Adult Hippocampus

Suh, H., Consiglio, A., Ray, J., Sawai, T., D’Amour, K. A., & Gage, F. H. (2007) · Cell stem cell · doi:10.1016/j.stem.2007.09.002 · Cited by 818 · see citing works

Regulation of synaptic connectivity by glia.

Eroglu, C., & Barres, B. A. (2010) · Nature · doi:10.1038/nature09612 · Cited by 813 · see citing works

Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain

Buffo, A., Rite, I., Tripathi, P., Lepier, A., Colak, D., Horn, A.-P., Mori, T., & Götz, M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0709002105 · Cited by 766 · see citing works

Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain

Levison, S. W., & Goldman, J. E. (1993) · Neuron · doi:10.1016/0896-6273(93)90311-e · Cited by 725 · see citing works

NG2 cells generate both oligodendrocytes and gray matter astrocytes

Zhu, X., Bergles, D. E., & Nishiyama, A. (2007) · Development · doi:10.1242/dev.004895 · Cited by 678 · see citing works

Synaptic Activation of Glutamate Transporters in Hippocampal Astrocytes

Bergles, D. E., & Jahr, C. E. (1997) · Neuron · doi:10.1016/s0896-6273(00)80420-1 · Cited by 516 · see citing works

Age-dependent fate and lineage restriction of single NG2 cells

Zhu, X., Hill, R. A., Dietrich, D., Komitova, M., Suzuki, R., & Nishiyama, A. (2011) · Development · doi:10.1242/dev.047951 · Cited by 464 · see citing works

Segregated Expression of AMPA-Type Glutamate Receptors and Glutamate Transporters Defines Distinct Astrocyte Populations in the Mouse Hippocampus

Matthias, K., Kirchhoff, F., Seifert, G., Hüttmann, K., Matyash, M., Kettenmann, H., & Steinhäuser, C. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-05-01750.2003 · Cited by 431 · see citing works

Choice of cranial window type for in vivo imaging affects dendritic spine turnover in the cortex

Xu, H., Pan, F., Yang, G., & Gan, W. (2007) · Nature Neuroscience · doi:10.1038/nn1883 · Cited by 413 · see citing works

Changing numbers of neuronal and non-neuronal cells underlie postnatal brain growth in the rat

Bandeira, F., Lent, R., & Herculano‐Houzel, S. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804650106 · Cited by 405 · see citing works

Glial cell lineage in the cerebral cortex: A review and synthesis

Cameron, R. S., & RAKIC, P. T. (1991) · Glia · doi:10.1002/glia.440040204 · Cited by 404 · see citing works

Live Astrocytes Visualized by Green Fluorescent Protein in Transgenic Mice

Zhuo, L., Sun, B., Zhang, C.-L., Fine, A., Chiu, S. Y., & Messing, A. (1997) · Developmental Biology · doi:10.1006/dbio.1997.8601 · Cited by 364 · see citing works

Evidence for division and transformations of neuroglia cells in the mouse brain, as derived from radioautography after injection of thymidine‐H3

Smart, I. H. M., & Leblond, C. P. (1961) · The Journal of Comparative Neurology · doi:10.1002/cne.901160307 · Cited by 274 · see citing works

Regional Distribution of Cortical Interneurons and Development of Inhibitory Tone Are Regulated by Cxcl12/Cxcr4 Signaling

Li, G., Adesnik, H., Li, J., Long, J., Nicoll, R. A., Rubenstein, J. L. R., & Pleasure, S. J. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4602-07.2008 · Cited by 209 · see citing works

Long-Term Potentiation of Neuron-Glia Synapses Mediated by Ca 2+ -Permeable AMPA Receptors

Ge, W., Yang, X.-J., Zhang, Z., Wang, H.-K., Shen, W., Deng, Q.-D., & Duan, S. (2006) · Science · doi:10.1126/science.1124669 · Cited by 208 · see citing works

Early patterns of migration, morphogenesis, and intermediate filament expression of subventricular zone cells in the postnatal rat forebrain

Zerlin, M., Levison, S. W., & Goldman, J. E. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-11-07238.1995 · Cited by 190 · see citing works

Dye-coupling between glial cells in the guinea pig neocortical slice

Gutnick, M. J., Connors, B. W., & Ransom, B. R. (1981) · Brain Research · doi:10.1016/0006-8993(81)90259-6 · Cited by 158 · see citing works

Gliogenic and neurogenic progenitors of the subventricular zone: Who are they, where did they come from, and where are they going?

Marshall, C. A. G., Suzuki, S. O., & Goldman, J. E. (2003) · Glia · doi:10.1002/glia.10213 · Cited by 144 · see citing works

Retrovirus-mediated single-cell gene knockout technique in adult newborn neurons in vivo

Tashiro, A., Zhao, C., & Gage, F. H. (2006) · Nature Protocols · doi:10.1038/nprot.2006.473 · Cited by 136 · see citing works

Early Postnatal Proteolipid Promoter-Expressing Progenitors Produce Multilineage CellsIn Vivo

Guo, F., Ma, J., McCauley, E., Bannerman, P. G. C., & Pleasure, D. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5653-08.2009 · Cited by 131 · see citing works

Evidence for large-scale astrocyte death in the developing cerebellum

Krueger, B., Burne, J., & Raff, M. C. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-05-03366.1995 · Cited by 120 · see citing works

Dividing glial cells maintain differentiated properties including complex morphology and functional synapses

Ge, W., Zhou, W., Luo, Q., Jan, L. Y., & Jan, Y. N. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811353106 · Cited by 104 · see citing works

Characterization of astrocyte‐specific conditional knockouts

Casper, K. B., Jones, K. A., & McCarthy, K. D. (2007) · genesis · doi:10.1002/dvg.20287 · Cited by 103 · see citing works

Biophysical Properties and Ionic Signature of Neuronal Progenitors of the Postnatal Subventricular Zone In Situ

Wang, D. D., Krueger‐Burg, D., & Bordey, A. (2003) · Journal of Neurophysiology · doi:10.1152/jn.01116.2002 · Cited by 77 · see citing works

Developmental and post‐injury cortical gliogenesis: A Genetic fate‐mapping study with Nestin‐CreER mice

Burns, K. A., Murphy, B. L., Danzer, S. C., & Kuan, C.-Y. (2008) · Glia · doi:10.1002/glia.20835 · Cited by 69 · see citing works

Persistent Enhancement of Neuron–Glia Signaling Mediated by Increased Extracellular K+ Accompanying Long-Term Synaptic Potentiation

Ge, W., & Duan, S. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00146.2006 · Cited by 36 · see citing works

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

Zhang, Y., Sloan, S. A., Clarke, L. E., Caneda, C., Plaza, C. A., Blumenthal, P. D., Vogel, H., Steinberg, G. K., Edwards, M. S. B., Li, G., et al. (2016) · Neuron · doi:10.1016/j.neuron.2015.11.013 · Cited by 2,295 · see citing works

Physiology of Astroglia

Verkhratsky, A., & Nedergaard, M. (2018) · Physiological Reviews · doi:10.1152/physrev.00042.2016 · Cited by 1,678 · see citing works

Astrocyte Crosstalk in CNS Inflammation

Linnerbauer, M., Wheeler, M. A., & Quintana, F. J. (2020) · Neuron · doi:10.1016/j.neuron.2020.08.012 · Cited by 989 · see citing works

Astrocyte reactivity and reactive astrogliosis: costs and benefits

Pekny, M., & Pekna, M. (2014) · Physiological Reviews · doi:10.1152/physrev.00041.2013 · Cited by 934 · see citing works

In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model

Guo, Z., Zhang, L., Wu, Z., Chen, Y., Wang, F., & Chen, G. (2013) · Cell stem cell · doi:10.1016/j.stem.2013.12.001 · Cited by 830 · see citing works

Identification of region-specific astrocyte subtypes at single cell resolution

Batiuk, M. Y., Martirosyan, A., Wahis, J., de Vin, F., Marneffe, C., Kusserow, C., Koeppen, J., Viana, J. F., Oliveira, J. F., Voet, T., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-14198-8 · Cited by 805 · see citing works

Astrocytes and disease: a neurodevelopmental perspective

Molofsky, A. V., Krenick, R., Ullian, E., Tsai, H.-H., Deneen, B., Richardson, W. D., Barres, B. A., & Rowitch, D. H. (2012) · Genes & Development · doi:10.1101/gad.188326.112 · Cited by 682 · see citing works

Function and therapeutic value of astrocytes in neurological diseases

Lee, H.-G., Wheeler, M. A., & Quintana, F. J. (2022) · Nature Reviews Drug Discovery · doi:10.1038/s41573-022-00390-x · Cited by 662 · see citing works

Molecular basis of astrocyte diversity and morphology across the CNS in health and disease

Endo, F., Kasai, A., Soto, J. S., Yu, X., Qu, Z., Hashimoto, H., Gradinaru, V., Kawaguchi, R., & Khakh, B. S. (2022) · Science · doi:10.1126/science.adc9020 · Cited by 560 · see citing works

Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson’s Disease

Chinta, S. J., Woods, G., Demaria, M., Rane, A., Zou, Y., McQuade, A., Rajagopalan, S., Limbad, C., Madden, D. T., Campisi, J., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2017.12.092 · Cited by 530 · see citing works

Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair

Tsai, H., Li, H., Fuentealba, L. C., Molofsky, A. V., Taveira‐Marques, R., Zhuang, H., Tenney, A., Murnen, A. T., Fancy, S. P. J., Merkle, F. T., et al. (2012) · Science · doi:10.1126/science.1222381 · Cited by 529 · see citing works

Identification of diverse astrocyte populations and their malignant analogs

John Lin, C.-C., Yu, K., Hatcher, A., Huang, T.-W., Lee, H. K., Carlson, J., Weston, M. C., Chen, F., Zhang, Y., Zhu, W., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4493 · Cited by 525 · see citing works

The Indispensable Roles of Microglia and Astrocytes during Brain Development

Reemst, K., Noctor, S. C., Lucassen, P. J., & Hol, E. M. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00566 · Cited by 516 · see citing works

Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map

Bayraktar, O. A., Bartels, T., Holmqvist, S., Kleshchevnikov, V., Martirosyan, A., Polioudakis, D., Ben Haim, L., Young, A. M. H., Batiuk, M. Y., Prakash, K., et al. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-0602-1 · Cited by 489 · see citing works

In vivo reprogramming of astrocytes to neuroblasts in the adult brain

Niu, W., Zang, T., Zou, Y., Fang, S., Smith, D. K., Bachoo, R. M., & Zhang, C. (2013) · Nature Cell Biology · doi:10.1038/ncb2843 · Cited by 485 · see citing works

The Emerging Nature of Astrocyte Diversity

Khakh, B. S., & Deneen, B. (2019) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-070918-050443 · Cited by 485 · see citing works

Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation

Bardehle, S., Krüger, M., Buggenthin, F., Schwausch, J., Ninkovic, J., Clevers, H. C., Snippert, H. J. G., Theis, F. J., Meyer‐Luehmann, M., Bechmann, I., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3371 · Cited by 423 · see citing works

Astrocytes, neurons, synapses: a tripartite view on cortical circuit development

Farhy-Tselnicker, I., & Allen, N. J. (2018) · Neural Development · doi:10.1186/s13064-018-0104-y · Cited by 396 · see citing works

Development of prefrontal cortex

Kolk, S. M., & Rakic, P. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-021-01137-9 · Cited by 378 · see citing works

Astrocyte regulation of synaptic behavior

Allen, N. J. (2014) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100913-013053 · Cited by 343 · see citing works

Astrocyte Development and HeterogeneityPreprint

Bayraktar, O. A., Fuentealba, L. C., Álvarez-Buylla, A., & Rowitch, D. H. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020362 · Cited by 339 · see citing works

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity

Molofsky, A. V., Kelley, K. W., Tsai, H., Redmond, S., Chang, S., Madireddy, L., Chan, J. R., Baranzini, S. E., Ullian, E. M., & Rowitch, D. H. (2014) · Nature · doi:10.1038/nature13161 · Cited by 312 · see citing works

Astrocyte development: A Guide for the Perplexed

Molofsky, A. V., & Deneen, B. (2015) · Glia · doi:10.1002/glia.22836 · Cited by 305 · see citing works

Synaptic Integration of Adult-Born Hippocampal Neurons Is Locally Controlled by Astrocytes

Sultan, S., Li, L., Moss, J., Petrelli, F., Cassé, F., Gebara, E., Lopatar, J., Pfrieger, F. W., Bezzi, P., Bischofberger, J., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.10.037 · Cited by 284 · see citing works

Reactive gliosis in the pathogenesis of CNS diseases

Pekny, M., & Pekna, M. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2015.11.014 · Cited by 276 · see citing works

Cell of Origin for Malignant Gliomas and Its Implication in Therapeutic DevelopmentPreprint

Zong, H., Parada, L. F., & Baker, S. J. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020610 · Cited by 267 · see citing works

Glial Cells as Progenitors and Stem Cells: New Roles in the Healthy and Diseased Brain

Dimou, L., & Götz, M. (2014) · Physiological Reviews · doi:10.1152/physrev.00036.2013 · Cited by 263 · see citing works

Mechanisms of astrocyte development and their contributions to neurodevelopmental disorders

Sloan, S. A., & Barres, B. A. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.03.005 · Cited by 248 · see citing works

Astrocyte Endfeet in Brain Function and Pathology: Open Questions

Díaz-Castro, B., Robel, S., & Mishra, A. (2023) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-091922-031205 · Cited by 238 · see citing works

The Glutamate–Glutamine (GABA) Cycle: Importance of Late Postnatal Development and Potential Reciprocal Interactions between Biosynthesis and Degradation

Hertz, L. (2013) · Frontiers in Endocrinology · doi:10.3389/fendo.2013.00059 · Cited by 235 · see citing works

Astrocyte morphology

Baldwin, K. T., Murai, K. K., & Khakh, B. S. (2023) · Trends in Cell Biology · doi:10.1016/j.tcb.2023.09.006 · Cited by 230 · see citing works

Maintaining genome stability in the nervous system

McKinnon, P. J. (2013) · Nature Neuroscience · doi:10.1038/nn.3537 · Cited by 229 · see citing works

Important Shapeshifter: Mechanisms Allowing Astrocytes to Respond to the Changing Nervous System During Development, Injury and Disease

Schiweck, J., Eickholt, B. J., & Murk, K. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00261 · Cited by 223 · see citing works

Protective Functions of Reactive Astrocytes Following Central Nervous System Insult

Linnerbauer, M., & Rothhammer, V. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.573256 · Cited by 221 · see citing works

Reactive astrocytes as neural stem or progenitor cells: In vivo lineage, In vitro potential, and Genome‐wide expression analysis

Götz, M., Sirko, S., Beckers, J., & Irmler, M. (2015) · Glia · doi:10.1002/glia.22850 · Cited by 219 · see citing works

Glial Development: The Crossroads of Regeneration and Repair in the CNS

Gallo, V., & Deneen, B. (2014) · Neuron · doi:10.1016/j.neuron.2014.06.010 · Cited by 219 · see citing works

Vascularization and Engraftment of Transplanted Human Cerebral Organoids in Mouse Cortex

Daviaud, N., Friedel, R. H., & Zou, H. (2018) · eNeuro · doi:10.1523/eneuro.0219-18.2018 · Cited by 219 · see citing works

Virus-Mediated Genome Editing via Homology-Directed Repair in Mitotic and Postmitotic Cells in Mammalian Brain

Nishiyama, J., Mikuni, T., & Yasuda, R. (2017) · Neuron · doi:10.1016/j.neuron.2017.10.004 · Cited by 215 · see citing works

Role of EGFR in the Nervous System

Romanò, R., & Bucci, C. (2020) · Cells · doi:10.3390/cells9081887 · Cited by 209 · see citing works

Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis

Weng, Q., Wang, J., Wang, J., He, D., Cheng, Z., Zhang, F., Verma, R., Xu, L., Dong, X., Liao, Y., et al. (2019) · Cell stem cell · doi:10.1016/j.stem.2019.03.006 · Cited by 206 · see citing works

Genetic and Stress-Induced Loss of NG2 Glia Triggers Emergence of Depressive-like Behaviors through Reduced Secretion of FGF2

Birey, F., Kloc, M. L., Chavali, M., Hussein, I., Wilson, M., Christoffel, D. J., Chen, T., Frohman, M. A., Robinson, J. K., Russo, S. J., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.10.046 · Cited by 204 · see citing works

Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain

Chakrabarty, P., Rosario, A. M., Cruz, P. E., Siemienski, Z. B., Ceballos‐Diaz, C., Crosby, K. W., Jansen, K. R., Borchelt, D., Kim, J., Jankowsky, J. L., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067680 · Cited by 201 · see citing works

Cellular and molecular introduction to brain development

Jiang, X., & Nardelli, J. (2015) · Neurobiology of Disease · doi:10.1016/j.nbd.2015.07.007 · Cited by 199 · see citing works

Single-cell delineation of lineage and genetic identity in the mouse brain

Bandler, R. C., Vitali, I., Delgado, R. N., Ho, M. C., Dvoretskova, E., Molinas, J. S. I., Frazel, P. W., Mohammadkhani, M., Machold, R. P., Mädler, S. C., et al. (2021) · Nature · doi:10.1038/s41586-021-04237-0 · Cited by 197 · see citing works

Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes

Masserdotti, G., Gillotin, S., Sutor, B., Drechsel, D., Irmler, M., Jørgensen, H. F., Sass, S., Theis, F. J., Beckers, J., Berninger, B., et al. (2015) · Cell stem cell · doi:10.1016/j.stem.2015.05.014 · Cited by 194 · see citing works

Evolving Concepts of Gliogenesis: A Look Way Back and Ahead to the Next 25 Years

Freeman, M. R., & Rowitch, D. H. (2013) · Neuron · doi:10.1016/j.neuron.2013.10.034 · Cited by 194 · see citing works

Diverse subtypes of astrocytes and their development during corticogenesis

Tabata, H. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00114 · Cited by 192 · see citing works

Multiplex Cell and Lineage Tracking with Combinatorial Labels

Loulier, K., Barry‐Martinet, R., Mahou, P., Franc, Y. L., Supatto, W., Matho, K. S., Ieng, S.-H., Fouquet, S., Dupin, É., Benosman, R. B., et al. (2014) · Neuron · doi:10.1016/j.neuron.2013.12.016 · Cited by 186 · see citing works

Astrocytes in Alzheimer's disease: pathological significance and molecular pathways

Preman, P., Alfonso-Triguero, M., Alberdi, E., Verkhratsky, A., & Arranz, A. M. (2021) · Cells · doi:10.3390/cells10030540 · Cited by 176 · see citing works

MEK Is a Key Regulator of Gliogenesis in the Developing Brain

Li, X., Newbern, J. M., Wu, Y., Morgan-Smith, M., Zhong, J., Charron, J., & Snider, W. D. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.031 · Cited by 171 · see citing works

Cortical astrocytes develop in a plastic manner at both clonal and cellular levels

Clavreul, S., Abdeladim, L., Hernández-Garzón, E., Niculescu, D., Durand, J., Ieng, S.-H., Barry‐Martinet, R., Bonvento, G., Beaurepaire, E., Livet, J., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12791-5 · Cited by 164 · see citing works

An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging

Yu, D., Gustafson, W. C., Han, C., Lafaye, C., Noirclerc‐Savoye, M., Ge, W., Thayer, D. A., Huang, H., Kornberg, T. B., Royant, A., et al. (2014) · Nature Communications · doi:10.1038/ncomms4626 · Cited by 162 · see citing works

Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities

Huang, A. Y.-S., Woo, J., Sardar, D., Lozzi, B., Huerta, N. A. B., Lin, C.-C. J., Felice, D., Jain, A., Paulucci-Holthauzen, A. A., & Deneen, B. (2020) · Neuron · doi:10.1016/j.neuron.2020.03.025 · Cited by 158 · see citing works

Astrocyte Differentiation of Human Pluripotent Stem Cells: New Tools for Neurological Disorder Research

Chandrasekaran, A., Avci, H. X., Leist, M., Kobolák, J., & Dinnyés, A. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00215 · Cited by 152 · see citing works

Asymmetric cell division of stem and progenitor cells during homeostasis and cancer

Gómez‐López, S., Lerner, R. G., & Petritsch, C. K. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1386-1 · Cited by 151 · see citing works

Morphological plasticity of astroglia: Understanding synaptic microenvironment

Heller, J. P., & Rusakov, D. A. (2015) · Glia · doi:10.1002/glia.22821 · Cited by 150 · see citing works

FUCCI sensors: powerful new tools for analysis of cell proliferation

Zielke, N., & Edgar, B. A. (2015) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.189 · Cited by 145 · see citing works

PDGF-B Is Required for Development of the Glymphatic System

Munk, A. S. F., Wang, W., Bèchet, N. B., Eltanahy, A. M., Cheng, A. X., Sigurðsson, B., Benraiss, A., Mäe, M. A., Kress, B. T., Kelley, D. H., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.02.050 · Cited by 141 · see citing works

Postnatal development of cerebrovascular structure and the neurogliovascular unit

Coelho‐Santos, V., & Shih, A. Y. (2019) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.363 · Cited by 141 · see citing works

A glial blueprint for gliomagenesis

Laug, D., Glasgow, S. M., & Deneen, B. (2018) · Nature reviews. Neuroscience · doi:10.1038/s41583-018-0014-3 · Cited by 139 · see citing works

A Competitive Advantage by Neonatally Engrafted Human Glial Progenitors Yields Mice Whose Brains Are Chimeric for Human Glia

Windrem, M. S., Schanz, S. J., Morrow, C., Munir, J., Chandler-Militello, D., Wang, S., & Goldman, S. A. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1510-14.2014 · Cited by 137 · see citing works

Heterogeneity of Astrocytes: From Development to Injury – Single Cell Gene Expression

Rusnakova, V., Honsa, P., Džamba, D., Ståhlberg, A., Kubista, M., & Anděrová, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069734 · Cited by 132 · see citing works

Developmental Cell Death in the Cerebral Cortex

Wong, F. K., & Marín, Ó. (2019) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100818-125204 · Cited by 128 · see citing works

Mechanisms of radial glia progenitor cell lineage progression

Beattie, R., & Hippenmeyer, S. (2017) · FEBS Letters · doi:10.1002/1873-3468.12906 · Cited by 127 · see citing works

Neurovascular Coupling in Development and Disease: Focus on Astrocytes

Stackhouse, T. L., & Mishra, A. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.702832 · Cited by 124 · see citing works

Astrocyte heterogeneity in the brain: from development to disease

Schitine, C., Nogaroli, L., Costa, M. R., & Hedin‐Pereira, C. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00076 · Cited by 120 · see citing works

Astrocytes and neurons share region-specific transcriptional signatures that confer regional identity to neuronal reprogramming

Herrero-Navarro, Á., Puche-Aroca, L., Moreno-Juan, V., Sempere-Ferràndez, A., Espinosa, A., Susín, R., Torres-Masjoan, L., Leyva-Díaz, E., Karow, M., Figueres-Oñate, M., et al. (2021) · Science Advances · doi:10.1126/sciadv.abe8978 · Cited by 117 · see citing works

Zbtb20 promotes astrocytogenesis during neocortical development

Nagao, M., Ogata, T., Sawada, Y., & Gotoh, Y. (2016) · Nature Communications · doi:10.1038/ncomms11102 · Cited by 117 · see citing works

YAP stabilizes SMAD1 and promotes BMP2-induced neocortical astrocytic differentiation

Huang, Z., Hu, J., Pan, J., Wang, Y., Hu, G., Zhou, J., Mei, L., & Xiong, W. (2016) · Development · doi:10.1242/dev.130658 · Cited by 116 · see citing works

Astrocytogenesis: where, when, and how

Akdemir, E. S., Huang, A. Y.-S., & Deneen, B. (2020) · F1000Research · doi:10.12688/f1000research.22405.1 · Cited by 115 · see citing works

Decoding Cortical Glial Cell Development

Li, X., Liu, G., Yang, L., Li, Z., Zhang, Z., Xu, Z., Cai, Y., Du, H., Su, Z., Wang, Z., et al. (2021) · Neuroscience Bulletin · doi:10.1007/s12264-021-00640-9 · Cited by 115 · see citing works

The emerging role of chromatin remodelers in neurodevelopmental disorders: a developmental perspective

Mossink, B., Negwer, M., Schubert, D., & Nadif Kasri, N. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03714-5 · Cited by 114 · see citing works

Developmental Origins of Astrocyte Heterogeneity: The Final Frontier of CNS Development

Chaboub, L. S., & Deneen, B. (2012) · Developmental Neuroscience · doi:10.1159/000343723 · Cited by 111 · see citing works

Mitochondrial biogenesis in developing astrocytes regulates astrocyte maturation and synapse formation

Zehnder, T., Petrelli, F., Romanos, J., Figueiredo, E. C. D. O., Lewis, T. L., Déglon, N., Polleux, F., Santello, M., & Bezzi, P. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108952 · Cited by 110 · see citing works

Astroglial asthenia and loss of function, rather than reactivity, contribute to the ageing of the brain

Verkhratsky, A., Augusto‐Oliveira, M., Pivoriūnas, A., Popov, A., Brazhe, A., & Semyanov, A. V. (2020) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-020-02465-3 · Cited by 108 · see citing works

Cell-type specific mechanisms of D-serine uptake and release in the brain

Martineau, M., Parpura, V., & Mothet, J. (2014) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2014.00012 · Cited by 108 · see citing works

A star is born: new insights into the mechanism of astrogenesis

Kanski, R., van Strien, M. E., van Tijn, P., & Hol, E. M. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1435-9 · Cited by 108 · see citing works

YAP Is a Critical Inducer of SOCS3, Preventing Reactive Astrogliosis

Huang, Z., Wang, Y., Hu, G., Zhou, J., Mei, L., & Xiong, W. (2015) · Cerebral Cortex · doi:10.1093/cercor/bhv292 · Cited by 107 · see citing works

Wide dispersion and diversity of clonally related inhibitory interneurons

Harwell, C. C., Fuentealba, L. C., Gonzalez-Cerrillo, A., Parker, P. R. L., Gertz, C. C., Mazzola, E., Garcia, M. T., Alvarez-Buylla, A., Cepko, C. L., & Kriegstein, A. R. (2015) · Neuron · doi:10.1016/j.neuron.2015.07.030 · Cited by 106 · see citing works

Activity-dependent modulation of synapse-regulating genes in astrocytes

Farhy-Tselnicker, I., Boisvert, M., Liu, H., Dowling, C. C., Erikson, G. A., Blanco‐Suárez, E., Farhy, C., Shokhirev, M. N., Ecker, J. R., & Allen, N. J. (2021) · eLife · doi:10.7554/elife.70514 · Cited by 106 · see citing works

Reactive Astrocytes in Central Nervous System Injury: Subgroup and Potential Therapy

Yu, G., Zhang, Y., & Ning, B. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.792764 · Cited by 106 · see citing works

Selective deletion of astroglial FMRP dysregulates glutamate transporter GLT1 and contributes to fragile X syndrome phenotypes in vivo.

Higashimori, H., Schin, C. S., Chiang, M. S. R., Morel, L., Shoneye, T. A., Nelson, D. L., & Yang, Y. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1069-16.2016 · Cited by 105 · see citing works

Neuronal and tumourigenic boundaries of glioblastoma plasticity

Silva, M. I. D., Stringer, B. W., & Bardy, C. (2022) · Trends in cancer · doi:10.1016/j.trecan.2022.10.010 · Cited by 103 · see citing works

Lrp4 in astrocytes modulates glutamatergic transmission

Sun, X.-D., Li, L., Liu, F., Huang, Z.-H., Bean, J. C., Jiao, H.-F., Barik, A., Kim, S.-M., Wu, H., Shen, C., et al. (2016) · Nature Neuroscience · doi:10.1038/nn.4326 · Cited by 102 · see citing works

Large-scale death of retinal astrocytes during normal development is non-apoptotic and implemented by microglia

Puñal, V. M., Paisley, C. E., Brecha, F. S., Lee, M. A., Perelli, R. M., Wang, J., O’Koren, E. G., Ackley, C. R., Saban, D. R., Reese, B. E., et al. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000492 · Cited by 101 · see citing works

Extensive transcriptional and chromatin changes underlie astrocyte maturation in vivo and in culture

Lattke, M., Goldstone, R. J., Ellis, J. K., Boeing, S., Jurado‐Arjona, J., Marichal, N., MacRae, J. I., Berninger, B., & Guillemot, F. (2021) · Nature Communications · doi:10.1038/s41467-021-24624-5 · Cited by 99 · see citing works

The Subventricular Zone Continues to Generate Corpus Callosum and Rostral Migratory Stream Astroglia in Normal Adult Mice

Sohn, J., Orosco, L. A., Guo, F., Chung, S., Bannerman, P. G. C., Ko, E. M., Zarbalis, K., Deng, W., & Pleasure, D. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.3454-14.2015 · Cited by 98 · see citing works

Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells

Beattie, R., Postiglione, M. P., Burnett, L. E., Laukoter, S., Streicher, C., Pauler, F. M., Xiao, G., Klezovitch, O., Vasioukhin, V. I., Ghashghaei, T., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.04.012 · Cited by 95 · see citing works

Multicolor multiscale brain imaging with chromatic multiphoton serial microscopy

Abdeladim, L., Matho, K. S., Clavreul, S., Mahou, P., Sintès, J.-M., Solinas, X., Arganda‐Carreras, I., Turney, S. G., Lichtman, J. W., Chessel, A., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09552-9 · Cited by 95 · see citing works

Astrocytes in the regulation of cerebrovascular functions

Cohen‐Salmon, M., Slaoui, L., Mazaré, N., Gilbert, A., Oudart, M., Alvear‐Perez, R., Elorza‐Vidal, X., Chever, O., & Boulay, A. (2021) · Glia · doi:10.1002/glia.23924 · Cited by 93 · see citing works

Mechanisms of astrocytogenesis in the mammalian brain

Namihira, M., & Nakashima, K. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.06.002 · Cited by 93 · see citing works

Developmental maturation of astrocytes and pathogenesis of neurodevelopmental disorders

Yang, Y., Higashimori, H., & Morel, L. (2013) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-5-22 · Cited by 93 · see citing works

The involvement of astrocytes in early‐life adversity induced programming of the brain

Abbink, M. R., van Deijk, A. F., Heine, V. M., Verheijen, M. H. G., & Kőrösi, A. (2019) · Glia · doi:10.1002/glia.23625 · Cited by 92 · see citing works

Diversity of Reactive Astrogliosis in CNS Pathology: Heterogeneity or Plasticity?

Moulson, A. J., Squair, J. W., Franklin, R. J. M., Tetzlaff, W., & Assinck, P. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.703810 · Cited by 90 · see citing works

Gliomas Interact with Non-glioma Brain Cells via Extracellular Vesicles

Gao, X., Zhang, Z., Mashimo, T., Shen, B., Nyagilo, J. O., Wang, H., Wang, Y., Liu, Z., Mulgaonkar, A., Hu, X.-L., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.01.089 · Cited by 88 · see citing works

Sex differences in developmental patterns of neocortical astroglia: A mouse translatome database

Rurak, G. M., Simard, S., Andrade, M. F., Lacoste, B., Charih, F., Geel, A. V., Stead, J. D. H., Woodside, B. C., Green, J. R., Coppola, G., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110310 · Cited by 87 · see citing works

Lineage Tracing Using Cux2-Cre and Cux2-CreERT2 Mice

Gil, C., Espinosa, A., Fregoso, S. P., Bluske, K. K., Cunningham, C. L., Martínez‐Garay, I., Zeng, H., Franco, S. J., & Müller, U. (2015) · Neuron · doi:10.1016/j.neuron.2015.04.019 · Cited by 87 · see citing works

No Longer Underappreciated: The Emerging Concept of Astrocyte Heterogeneity in Neuroscience

Pestana, F., Edwards‐Faret, G., Belgard, T. G., Martirosyan, A., & Holt, M. G. (2020) · Brain Sciences · doi:10.3390/brainsci10030168 · Cited by 86 · see citing works

Recent insights on astrocyte mechanisms in CNS homeostasis, pathology, and repair

Hart, C. G., & Karimi‐Abdolrezaee, S. (2021) · Journal of Neuroscience Research · doi:10.1002/jnr.24922 · Cited by 85 · see citing works

Emerging evidence for astrocyte dysfunction in schizophrenia

Figueiredo, E. C. D. O., Calì, C., Petrelli, F., & Bezzi, P. (2022) · Glia · doi:10.1002/glia.24221 · Cited by 85 · see citing works

Local production of astrocytes in the cerebral cortex

Ge, W.-P., & Jia, J.-M. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2015.08.057 · Cited by 58 · see citing works

Sourcing local produce

Welberg, L. (2012) · Nature reviews. Neuroscience · doi:10.1038/nrn3247

Astrogenesis versus astrogliosis

Koob, A. O. (2017) · Neural Regeneration Research · doi:10.4103/1673-5374.200798 · Cited by 4 · see citing works

The Germinative Zone Produces the Most Cortical Astrocytes after Neuronal Migration in the Developing Mammalian Brain

Gressèns, P., Richelme, C., Kadhim, H. J., Gadisseux, J., & Evrard, P. (2009) · Biology of the Neonate · doi:10.1159/000243526 · Cited by 141 · see citing works

Cortical astrocytes develop in a plastic manner at both clonal and cellular levels

Clavreul, S., Abdeladim, L., Hernández-Garzón, E., Niculescu, D., Durand, J., Ieng, S.-H., Barry‐Martinet, R., Bonvento, G., Beaurepaire, E., Livet, J., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12791-5 · Cited by 164 · see citing works