Age-dependent fate and lineage restriction of single NG2 cells

Generalized lacZ expression with the ROSA26 Cre reporter strain

Soriano, P. (1999) · Nature Genetics · doi:10.1038/5007 · Cited by 5,237 · see citing works

A global double-fluorescent Cre reporter mouse

Muzumdar, M. D., Tasic, B., Miyamichi, K., Li, L., & Luo, L. (2007) · genesis · doi:10.1002/dvg.20335 · Cited by 3,491 · see citing works

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4178-07.2008 · Cited by 3,129 · see citing works

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

RAFF, M. C., Miller, R. H., & Noble, M. (1983) · Nature · doi:10.1038/303390a0 · Cited by 2,030 · see citing works

Efficient Recombination in Diverse Tissues by a Tamoxifen-Inducible Form of Cre: A Tool for Temporally Regulated Gene Activation/Inactivation in the Mouse

Hayashi, S., & McMahon, A. P. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0597 · Cited by 1,347 · see citing works

Cell death and control of cell survival in the oligodendrocyte lineage

Barres, B. A., Hart, I. K., Coles, H. S. R., Burne, J. F., Voyvodic, J. T., Richardson, W. D., & Raff, M. C. (1992) · Cell · doi:10.1016/0092-8674(92)90531-g · Cited by 1,345 · see citing works

Origin of oligodendrocytes in the subventricular zone of the adult brain

Menn, B., Garcia-Verdugo, J. M., Yaschine, C., Gonzalez-Perez, O., Rowitch, D., & Alvarez-Buylla, A. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1299-06.2006 · Cited by 972 · see citing works

PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice

Rivers, L. E., Young, K. M., Rizzi, M., Jamen, F., Psachoulia, K., Wade, A., Kessaris, N., & Richardson, W. D. (2008) · Nature Neuroscience · doi:10.1038/nn.2220 · Cited by 961 · see citing works

NG2-expressing glial progenitor cells: an abundant and widespread population of cycling cells in the adult rat CNS

Dawson, M. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(03)00210-0 · Cited by 927 · see citing works

Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity

Nishiyama, A., Komitova, M., Suzuki, R., & Zhu, X. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2495 · Cited by 865 · see citing works

Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon cre-mediated excision

Novak, A., Guo, C., Yang, W., Nagy, A., & Lobe, C. G. (2000) · genesis · doi:10.1002/1526-968x(200011/12)28:3/4 · Cited by 841 · see citing works

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

Littlewood, T. D., Hancock, D. C., Danielian, P. S., Parker, M. G., & Evan, G. I. (1995) · Nucleic Acids Research · doi:10.1093/nar/23.10.1686 · Cited by 780 · see citing works

NG2 cells generate both oligodendrocytes and gray matter astrocytes

Zhu, X., Bergles, D. E., & Nishiyama, A. (2007) · Development · doi:10.1242/dev.004895 · Cited by 678 · see citing works

Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex

Dimou, L., Simon, C., Kirchhoff, F., Takebayashi, H., & Götz, M. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.2831-08.2008 · Cited by 551 · see citing works

The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages.

Takebayashi, H., Nabeshima, Y., Yoshida, S., Chisaka, O., Ikenaka, K., & Nabeshima, Y. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00926-0 · Cited by 500 · see citing works

Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

Shen, S., Sandoval, J., Swiss, V. A., Li, J., Dupree, J. L., Franklin, R. J. M., & Casaccia‐Bonnefil, P. (2008) · Nature Neuroscience · doi:10.1038/nn.2172 · Cited by 486 · see citing works

Identification of an adult-specific glial progenitor cell

Wolswijk, G., & Noble, M. A. (1989) · Development · doi:10.1242/dev.105.2.387 · Cited by 485 · see citing works

Clonal analysis of oligodendrocyte development in culture: Evidence for a developmental clock that counts cell divisions

Temple, S., & RAFF, M. C. (1986) · Cell · doi:10.1016/0092-8674(86)90843-3 · Cited by 455 · see citing works

Electron microscopic autoradiographic studies of gliogenesis in rat optic nerve I. Cell proliferation

Skoff, R. P., Price, D. L., & Stocks, A. (1976) · The Journal of Comparative Neurology · doi:10.1002/cne.901690303 · Cited by 362 · see citing works

Electron microscopic autoradiographic studies of gliogenesis in rat optic nerve. II. Time of origin

Skoff, R. P., Price, D. L., & Stocks, A. (1976) · Journal of Comparative Neurology · doi:10.1002/cne.901690304 · Cited by 312 · see citing works

MYELINATION OF THE MOUSE CORPUS CALLOSUM

Sturrock, R. R. (1980) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1980.tb00219.x · Cited by 289 · see citing works

Glial-Restricted Precursors Are Derived from Multipotent Neuroepithelial Stem Cells

Rao, M. S. R., & Mayer‐Pröschel, M. (1997) · Developmental Biology · doi:10.1006/dbio.1997.8597 · Cited by 286 · see citing works

Cell cycle dynamics of NG2 cells in the postnatal and ageing brain

Psachoulia, K., Jamen, F., Young, K. M., & Richardson, W. D. (2009) · Neuron Glia Biology · doi:10.1017/s1740925x09990354 · Cited by 257 · see citing works

Interaction between NG2 proteoglycan and PDGF ?-receptor on O2A progenitor cells is required for optimal response to PDGF

Nishiyama, A., Lin, X., Giese, N. A., Heldin, C., & Stallcup, W. B. (1996) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19960201)43:3 · Cited by 239 · see citing works

Identification of residues in the estrogen receptor that confer differential sensitivity to estrogen and hydroxytamoxifen

Danielian, P. S., White, R., Hoare, S., Fawell, S. E., & Parker, M. G. (1993) · Molecular Endocrinology · doi:10.1210/mend.7.2.8469236 · Cited by 220 · see citing works

Pyramidal Neurons Are Generated from Oligodendroglial Progenitor Cells in Adult Piriform Cortex

Guo, F., Maeda, Y., Ma, J., Xu, J., Horiuchi, M., Miers, L. A., Vaccarino, F. M., & Pleasure, D. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1360-10.2010 · Cited by 176 · see citing works

NG2 cells generate oligodendrocytes and gray matter astrocytes in the spinal cord.

Zhu, X., Hill, R., & Nishiyama, A. (2008) · Neuron Glia Biology · doi:10.1017/s1740925x09000015 · Cited by 168 · see citing works

Spatial and temporal expression of S100B in cells of oligodendrocyte lineage

Hachem, S., Aguirre, A., Vives, V., Marks, A., Gallo, V., & Legraverend, C. (2005) · Glia · doi:10.1002/glia.20184 · Cited by 167 · see citing works

Neurogenesis and asymmetric cell division

Zhong, W., & Chia, W. N. (2008) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2008.05.002 · Cited by 163 · see citing works

In vitro analysis of the origin and maintenance of O-2Aadult progenitor cells.

Wren, D. R., Wolswijk, G., & Noble, M. A. (1992) · The Journal of Cell Biology · doi:10.1083/jcb.116.1.167 · Cited by 144 · see citing works

Radioautographic evidence for slow astrocyte turnover and modest oligodendrocyte production in the corpus callosum of adult mice infused with ³ H‐thymidine

McCarthy, G. F., & Leblond, C. P. (1988) · Journal of Comparative Neurology · doi:10.1002/cne.902710409 · Cited by 134 · see citing works

Early Postnatal Proteolipid Promoter-Expressing Progenitors Produce Multilineage CellsIn Vivo

Guo, F., Ma, J., McCauley, E., Bannerman, P. G. C., & Pleasure, D. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5653-08.2009 · Cited by 131 · see citing works

Glial cells are born with synapses

Kukley, M., Kiladze, M., Tognatta, R., Hans, M., Swandulla, D., Schramm, J., & Dietrich, D. (2008) · The FASEB Journal · doi:10.1096/fj.07-090985 · Cited by 129 · see citing works

GFAP‐GFP neural progenitors are antigenically homogeneous and anchored in their enclosed mosaic niche

Platel, J., Gordon, V., Heintz, T. G., & Bordey, A. (2008) · Glia · doi:10.1002/glia.20735 · Cited by 110 · see citing works

NG2 cells are distinct from neurogenic cells in the postnatal mouse subventricular zone

Komitova, M., Zhu, X., Serwanski, D. R., & Nishiyama, A. (2008) · The Journal of Comparative Neurology · doi:10.1002/cne.21917 · Cited by 93 · see citing works

Stable maintenance of glutamate receptors and other synaptic components in long‐term hippocampal slices

Bahr, B. A., Kessler, M., Rivera, S., Vanderklish, P. W., Hall, R. A., Mutneja, M. S., Gall, C. M., & Hoffman, K. B. (1995) · Hippocampus · doi:10.1002/hipo.450050505 · Cited by 91 · see citing works

Analysis of Stem Cell Lineage Progression in the Neonatal Subventricular Zone Identifies EGFR+/NG2− Cells as Transit‐Amplifying Precursors

Cesetti, T., Obernier, K., Bengtson, C., Fila, T., Mandl, C., Hölzl-Wenig, G., Wörner, K., Eckstein, V., & Ciccolini, F. (2009) · Stem Cells · doi:10.1002/stem.74 · Cited by 54 · see citing works

Junin virus‐induced astrocytosis is impaired by iNOS inhibition

Gomez, R. M., Yep, A., Schattner, M. A., & Berría, M. I. (2002) · Journal of Medical Virology · doi:10.1002/jmv.10254 · Cited by 24 · see citing works

Gradual inhibition of inducible nitric oxide synthase but not of interleukin-1β production in rat microglial cells of endotoxin- treated mixed glial cell cultures

(1996) · Pure Amsterdam UMC · doi:10.1002/(sici)1098-1136(199606)17:2

Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow

Zhou, B. O., Yue, R., Murphy, M. M., Peyer, J. G., & Morrison, S. J. (2014) · Cell Stem Cell · doi:10.1016/j.stem.2014.06.008 · Cited by 1,381 · see citing works

Arteriolar niches maintain haematopoietic stem cell quiescence

Kunisaki, Y., Bruns, I., Scheiermann, C., Ahmed, J. U., Pinho, S., Zhang, D., Mizoguchi, T., Wei, Q., Lucas, D., Ito, K., et al. (2013) · Nature · doi:10.1038/nature12612 · Cited by 1,236 · see citing works

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

Rock, J. R., Barkauskas, C. E., Cronce, M. J., Xue, Y., Harris, J. R., Liang, J., Noble, P. W., & Hogan, B. L. M. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1117988108 · Cited by 1,033 · see citing works

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

Young, K. M., Psachoulia, K., Tripathi, R. B., Dunn, S.-J., Cossell, L., Attwell, D., Tohyama, K., & Richardson, W. D. (2013) · Neuron · doi:10.1016/j.neuron.2013.01.006 · Cited by 872 · see citing works

Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes

Hill, R., Тонг, Л., Yuan, P., Murikinati, S. R., Gupta, S., & Grutzendler, J. (2015) · Neuron · doi:10.1016/j.neuron.2015.06.001 · Cited by 704 · see citing works

Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal

Acar, M., Kocherlakota, K. S., Murphy, M. M., Peyer, J. G., Oguro, H., Inra, C. N., Jaiyeola, C., Zhao, Z., Luby‐Phelps, K., & Morrison, S. J. (2015) · Nature · doi:10.1038/nature15250 · Cited by 702 · see citing works

Oligodendrocytes in development, myelin generation and beyond

Kuhn, S., Gritti, L., Crooks, D., & Dombrowski, Y. (2019) · Cells · doi:10.3390/cells8111424 · Cited by 625 · see citing works

Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis

Kang, S. H., Li, Y., Fukaya, M., Lorenzini, I., Cleveland, D. W., Ostrow, L. W., Rothstein, J. D., & Bergles, D. E. (2013) · Nature Neuroscience · doi:10.1038/nn.3357 · Cited by 599 · see citing works

Oligodendrocyte Development and PlasticityPreprint

Bergles, D. E., & Richardson, W. D. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020453 · Cited by 573 · see citing works

Adrenergic nerves activate an angio-metabolic switch in prostate cancer

Zahalka, A. H., Arnal-Estapé, A., Maryanovich, M., Nakahara, F., Cruz, C. D., Finley, L. W. S., & Frenette, P. S. (2017) · Science · doi:10.1126/science.aah5072 · Cited by 548 · see citing works

Dynamics of Oligodendrocyte Generation and Myelination in the Human Brain

Yeung, M. S. Y., Zdunek, S., Bergmann, O., Bernard, S., Salehpour, M., Alkass, K., Perl, S., Tisdale, J., Possnert, G., Brundin, L., et al. (2014) · Cell · doi:10.1016/j.cell.2014.10.011 · Cited by 541 · see citing works

Local generation of glia is a major astrocyte source in postnatal cortex

Ge, W.-P., Miyawaki, A., Gage, F. H., Jan, Y. N., & Jan, L. Y. (2012) · Nature · doi:10.1038/nature10959 · Cited by 507 · see citing works

Rapid production of new oligodendrocytes is required in the earliest stages of motor-skill learning

Xiao, L., Ohayon, D., McKenzie, I. A., Sinclair-Wilson, A., Wright, J. L., Fudge, A. D., Emery, B., Li, H., & Richardson, W. D. (2016) · Nature Neuroscience · doi:10.1038/nn.4351 · Cited by 507 · see citing works

Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues

Bartosovic, M., Kabbe, M., & Castelo-Branco, G. (2021) · Nature Biotechnology · doi:10.1038/s41587-021-00869-9 · Cited by 483 · see citing works

Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain

Hill, R. A., Li, A. M., & Grutzendler, J. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0120-6 · Cited by 467 · see citing works

Perivascular Fibroblasts Form the Fibrotic Scar after Contusive Spinal Cord Injury

Soderblom, C., Luo, X., Blumenthal, E., Bray, E. R., Lyapichev, K. A., Ramos, J., Krishnan, V., Lai-Hsu, C., Park, K. K., Tsoulfas, P., et al. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2524-13.2013 · Cited by 419 · see citing works

Dual origin of mesenchymal stem cells contributing to organ growth and repair

Feng, J., Mantesso, A., Bari, C. D., Nishiyama, A., & Sharpe, P. T. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015449108 · Cited by 412 · see citing works

Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss

Nikolakopoulou, A. M., Montagne, A., Kisler, K., Dai, Z., Wang, Y., Huuskonen, M. T., Sagare, A. P., Lazić, D., Sweeney, M. D., Kong, P., et al. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0434-z · Cited by 382 · see citing works

Myelin plasticity: sculpting circuits in learning and memory

Xin, W., & Chan, J. R. (2020) · Nature Reviews Neuroscience · doi:10.1038/s41583-020-00379-8 · Cited by 329 · see citing works

Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery

Mei, F., Lehmann‐Horn, K., Shen, Y. A., Rankin, K. A., Stebbins, K. J., Lorrain, D. S., Pekarek, K. L., Sagan, S. A., Xiao, L., Teuscher, C., et al. (2016) · eLife · doi:10.7554/elife.18246 · Cited by 323 · see citing works

Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice

Hartmann, D. A., Underly, R. G., Grant, R. I., Watson, A. N., Lindner, V., & Shih, A. Y. (2015) · Neurophotonics · doi:10.1117/1.nph.2.4.041402 · Cited by 306 · see citing works

Myelin plasticity and nervous system function

Monje, M. (2018) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-080317-061853 · Cited by 274 · see citing works

NG2-glia as multipotent neural stem cells: fact or fantasy?

Richardson, W. D., Young, K. M., Tripathi, R. B., & McKenzie, I. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.013 · Cited by 300 · see citing works

Organizational hierarchy and structural diversity of microvascular pericytes in adult mouse cortex

Grant, R. I., Hartmann, D. A., Underly, R. G., Berthiaume, A., Bhat, N. R., & Shih, A. Y. (2017) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x17732229 · Cited by 278 · see citing works

Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization

Er, E. E., Valiente, M., Ganesh, K., Zou, Y., Agrawal, S., Hu, J. Y., Griscom, B., Rosenblum, M. K., Boire, A. A., Brogi, E., et al. (2018) · Nature Cell Biology · doi:10.1038/s41556-018-0138-8 · Cited by 282 · see citing works

A perisinusoidal niche for extramedullary haematopoiesis in the spleen

Inra, C. N., Zhou, B. O., Acar, M., Murphy, M. M., Richardson, J. A., Zhao, Z., & Morrison, S. J. (2015) · Nature · doi:10.1038/nature15530 · Cited by 269 · see citing works

Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1

Eilken, H. M., Diéguez‐Hurtado, R., Schmidt, I., Nakayama, M., Jeong, H., Arf, H., Adams, S., Ferrara, N., & Adams, R. H. (2017) · Nature Communications · doi:10.1038/s41467-017-01738-3 · Cited by 270 · see citing works

Glial cells as progenitors and stem cells: new roles in the healthy and diseased brain.

Dimou, L., & Götz, M. (2014) · Physiological Reviews · doi:10.1152/physrev.00036.2013 · Cited by 259 · see citing works

NG 2‐glia and their functions in the central nervous system

Dimou, L., & Gallo, V. (2015) · Glia · doi:10.1002/glia.22859 · Cited by 258 · see citing works

Astrocytes and Aging

Palmer, A. L., & Ousman, S. S. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00337 · Cited by 247 · see citing works

Wrapped to Adapt: Experience-Dependent Myelination

Mount, C., & Monje, M. (2017) · Neuron · doi:10.1016/j.neuron.2017.07.009 · Cited by 251 · see citing works

Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation

Marisca, R., Hoche, T., Agirre, E., Hoodless, L. J., Barkey, W., Auer, F., Castelo‐Branco, G., & Czopka, T. (2020) · Nature Neuroscience · doi:10.1038/s41593-019-0581-2 · Cited by 246 · see citing works

Aberrant oligodendroglial–vascular interactions disrupt the blood–brain barrier, triggering CNS inflammation

Niu, J., Tsai, H., Hoi, K. K., Huang, N., Yu, G., Kim, K., Baranzini, S. E., Xiao, L., Chan, J. R., & Fancy, S. P. J. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0369-4 · Cited by 241 · see citing works

Origins and Proliferative States of Human Oligodendrocyte Precursor Cells

Huang, W., Bhaduri, A., Velmeshev, D., Wang, S., Wang, L., Rottkamp, C. A., Álvarez-Buylla, A., Rowitch, D. H., & Kriegstein, A. R. (2020) · Cell · doi:10.1016/j.cell.2020.06.027 · Cited by 234 · see citing works

Dynamic Remodeling of Pericytes In Vivo Maintains Capillary Coverage in the Adult Mouse Brain

Berthiaume, A.-A., Grant, R. I., McDowell, K. P., Underly, R. G., Hartmann, D. A., Levy, M., Bhat, N. R., & Shih, A. Y. (2018) · Cell Reports · doi:10.1016/j.celrep.2017.12.016 · Cited by 223 · see citing works

Pericytes are progenitors for coronary artery smooth muscle

Volz, K. S., Jacobs, A. H., Chen, H. I., Poduri, A., McKay, A. S., Riordan, D. P., Kofler, N. M., Kitajewski, J., Weissman, I. L., & Red‐Horse, K. (2015) · eLife · doi:10.7554/elife.10036 · Cited by 227 · see citing works

Asymmetry-Defective Oligodendrocyte Progenitors Are Glioma Precursors

Sugiarto, S., Persson, A. I., González-Muñoz, E., Waldhuber, M., Lamagna, C., Andor, N., Hanecker, P., Ayers-Ringler, J. R., Phillips, J. J., Siu, J. J., et al. (2011) · Cancer Cell · doi:10.1016/j.ccr.2011.08.011 · Cited by 223 · see citing works

Reactive astrocytes as neural stem or progenitor cells: In vivo lineage, In vitro potential, and Genome‐wide expression analysis

Götz, M., Sirko, S., Beckers, J., & Irmler, M. (2015) · Glia · doi:10.1002/glia.22850 · Cited by 219 · see citing works

Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain

Viganò, F., Möbius, W., Götz, M., & Dimou, L. (2013) · Nature Neuroscience · doi:10.1038/nn.3503 · Cited by 220 · see citing works

Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men

Behrendt, G., Baer, K., Buffo, A., Curtis, M. A., Faull, R. L., Rees, M. I., Götz, M., & Dimou, L. (2013) · Glia · doi:10.1002/glia.22432 · Cited by 219 · see citing works

Adult Lineage Restricted CNS Progenitors Specify Distinct Glioblastoma Subtypes

Llaguno, S. A. A., Wang, Z.-L., Sun, D., Chen, J., Xu, J., Kim, E. J., Hatanpaa, K., Raisanen, J., Burns, D., Johnson, J. E., et al. (2015) · Cancer Cell · doi:10.1016/j.ccell.2015.09.007 · Cited by 208 · see citing works

Genetic and Stress-Induced Loss of NG2 Glia Triggers Emergence of Depressive-like Behaviors through Reduced Secretion of FGF2

Birey, F., Kloc, M. L., Chavali, M., Hussein, I., Wilson, M., Christoffel, D. J., Chen, T., Frohman, M. A., Robinson, J. K., Russo, S. J., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.10.046 · Cited by 204 · see citing works

Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia

Wang, F., Yang, Y., Yang, N., Chen, X., Huang, N.-X., Zhang, J., Wu, Y., Liu, Z., Gao, X., Li, T., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.07.017 · Cited by 204 · see citing works

Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage

Petersen, M. A., Ryu, J. K., Chang, K.-J., Etxeberría, A., Bardehle, S., Mendiola, A. S., Kamau-Devers, W., Fancy, S. P. J., Thor, A., Bushong, E. A., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.10.008 · Cited by 198 · see citing works

Genetic Lineage Tracing of Nonmyocyte Population by Dual Recombinases

Li, Y., He, L., Huang, X., Bhaloo, S. I., Zhao, H., Zhang, S., Pu, W., Tian, X., Liu, Q., Liu, Q., et al. (2018) · Circulation · doi:10.1161/circulationaha.118.034250 · Cited by 205 · see citing works

Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification

Dey, D., Bagarova, J., Hatsell, S. J., Armstrong, K. A., Huang, L., Ermann, J., Vonner, A. J., Shen, Y., Mohedas, A. H., Lee, A. M., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aaf1090 · Cited by 195 · see citing works

Emerging roles for CNS fibroblasts in health, injury and disease

Dorrier, C., Jones, H. E., Pintarić, L., Siegenthaler, J. A., & Daneman, R. (2021) · Nature reviews. Neuroscience · doi:10.1038/s41583-021-00525-w · Cited by 194 · see citing works

Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division

Hill, R., Patel, K. D., Gonçalves, C. M., Grutzendler, J., & Nishiyama, A. (2014) · Nature Neuroscience · doi:10.1038/nn.3815 · Cited by 186 · see citing works

Mouse strains to study cold-inducible beige progenitors and beige adipocyte formation and function

Berry, D. C., Jiang, Y., & Graff, J. M. (2016) · Nature Communications · doi:10.1038/ncomms10184 · Cited by 185 · see citing works

Pericytes as Inducers of Rapid, Matrix Metalloproteinase-9-Dependent Capillary Damage during Ischemia

Underly, R. G., Levy, M. S., Hartmann, D. A., Grant, R. I., Watson, A. N., & Shih, A. Y. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.2891-16.2016 · Cited by 181 · see citing works

Properties and fate of oligodendrocyte progenitor cells in the corpus callosum, motor cortex, and piriform cortex of the mouse

Clarke, L. E., Young, K. M., Hamilton, N. B., Li, H., Richardson, W. D., & Attwell, D. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0928-12.2012 · Cited by 182 · see citing works

Novel NG2‐CreERT2 knock‐in mice demonstrate heterogeneous differentiation potential of NG2 glia during development

Huang, W., Zhao, N., Bai, X., Karram, K., Trotter, J., Goebbels, S., Scheller, A., & Kirchhoff, F. (2014) · Glia · doi:10.1002/glia.22648 · Cited by 177 · see citing works

Oligodendrogenesis in the normal and pathological central nervous system

Waly, B. E., Macchi, M., Cayre, M., & Durbec, P. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00145 · Cited by 176 · see citing works

Neural stem cells in the adult spinal cord

Sabelström, H., Stenudd, M., & Frisén, J. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2013.01.026 · Cited by 181 · see citing works

A unifying hypothesis on mammalian neural stem cell properties in the adult hippocampus

Bonaguidi, M. A., Song, J., Ming, G., & Song, H. (2012) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2012.03.013 · Cited by 176 · see citing works

Inhibition of Gli1 mobilizes endogenous neural stem cells for remyelination

Samanta, J., Grund, E. M., Silva, H. M., Lafaille, J. J., Fishell, G., & Salzer, J. L. (2015) · Nature · doi:10.1038/nature14957 · Cited by 170 · see citing works

NG2 Cells in White Matter But Not Gray Matter Proliferate in Response to PDGF

Hill, R., Patel, K. D., Medved, J., Reiss, A., & Nishiyama, A. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2001-12.2013 · Cited by 165 · see citing works

Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain

Zhan, L., Krabbe, G., Du, F., Jones, I., Reichert, M. C., Telpoukhovskaia, M., Kodama, L., Wang, C., Cho, S.-H., Sayed, F., et al. (2019) · PLOS Biology · doi:10.1371/journal.pbio.3000134 · Cited by 163 · see citing works

Oligodendroglia and Myelin in Neurodegenerative Diseases: More Than Just Bystanders?

Ettle, B., Schlachetzki, J. C. M., & Winkler, J. (2016) · Molecular Neurobiology · doi:10.1007/s12035-015-9205-3 · Cited by 160 · see citing works

Small molecules combined with collagen hydrogel direct neurogenesis and migration of neural stem cells after spinal cord injury

Yang, Y., Fan, Y., Zhang, H., Zhang, Q., Zhao, Y., Xiao, Z., Liu, W., Chen, B., Gao, L., Sun, Z., et al. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120479 · Cited by 159 · see citing works

Ascl1/Mash1 Promotes Brain Oligodendrogenesis during Myelination and Remyelination

Nakatani, H., Martin, E., Hassani, H., Clavairoly, A., Maire, C. L., Viadieu, A., Kerninon, C., Delmasure, A., Frah, M., Weber, M., et al. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0805-13.2013 · Cited by 158 · see citing works

Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators

Silberstein, L., Goncalves, K. A., Kharchenko, P. V., Turcotte, R., Kfoury, Y. S., Mercier, F., Baryawno, N., Sévère, N., Bachand, J., Spencer, J. A., et al. (2016) · Cell stem cell · doi:10.1016/j.stem.2016.07.004 · Cited by 156 · see citing works

Asymmetric cell division of stem and progenitor cells during homeostasis and cancer

Gómez‐López, S., Lerner, R. G., & Petritsch, C. K. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1386-1 · Cited by 151 · see citing works

Regulation and function of neurogenesis in the adult mammalian hypothalamus

Yoo, S., & Blackshaw, S. (2018) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.04.001 · Cited by 149 · see citing works

Gli1+ Periodontium Stem Cells Are Regulated by Osteocytes and Occlusal Force

Men, Y., Wang, Y., Yi, Y., Jing, D., Luo, W., Shen, B., Stenberg, W. V., Chai, Y., Ge, W., Feng, J. Q., et al. (2020) · Developmental Cell · doi:10.1016/j.devcel.2020.06.006 · Cited by 149 · see citing works

Cell of all trades: oligodendrocyte precursor cells in synaptic, vascular, and immune functionPreprint

Akay, L. A., Effenberger, A. H., & Tsai, L. (2021) · Genes & Development · doi:10.1101/gad.344218.120 · Cited by 142 · see citing works

Olig2-dependent developmental fate switch of NG2 cells

Zhu, X., Zuo, H., Maher, B., Serwanski, D., Loturco, J., Lu, Q. R., & Nishiyama, A. (2012) · Development · doi:10.1242/dev.078873 · Cited by 134 · see citing works

A Glial Blueprint for Gliomagenesis

Laug, D., Glasgow, S. M., & Deneen, B. (2018) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0014-3 · Cited by 131 · see citing works

Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis

Xie, T., Liang, J., Liu, N., Huan, C., Zhang, Y., Liu, W., Kumar, M. E., Xiao, R., D'Armiento, J. M., METZGER, D., et al. (2016) · Journal of Clinical Investigation · doi:10.1172/jci85328 · Cited by 137 · see citing works

Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice

Reinert, R. B., Kantz, J., Misfeldt, A. A., Poffenberger, G., GANNON, M. A., Briššová, M., & Powers, A. C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033529 · Cited by 133 · see citing works

NG2 glia regulate brain innate immunity via TGF-β2/TGFBR2 axis

Zhang, S.-Z., Wang, Q., Yang, Q., Gu, H., Yin, Y., Li, Y., Hou, J., Chen, R., Sun, Q., Sun, Y., et al. (2019) · BMC Medicine · doi:10.1186/s12916-019-1439-x · Cited by 138 · see citing works

Disruption of oligodendrocyte progenitor cells is an early sign of pathology in the triple transgenic mouse model of Alzheimer's disease

Vanzulli, I., Papanikolaou, M., De-La-Rocha, I. C., Pieropan, F., Rivera, A. D., Gomez-Nicola, D., Verkhratsky, A., Rodríguez, J. J., & Butt, A. M. (2020) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2020.05.016 · Cited by 130 · see citing works

Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process

Galvão, R. P., Kasina, A., McNeill, R. S., Harbin, J. E., Foreman, O., Verhaak, R. G. W., Nishiyama, A., Miller, C. R., & Zong, H. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1414389111 · Cited by 126 · see citing works

Myelin plasticity in the central nervous system

Purger, D. A., Gibson, E. M., & Monje, M. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.08.001 · Cited by 126 · see citing works

Chromatin Landscape Defined by Repressive Histone Methylation during Oligodendrocyte Differentiation

Liu, J., Magri, L., Zhang, F., Marsh, N. O., Albrecht, S., Huynh, J. L., Kaur, J., Kuhlmann, T., Zhang, W., Slesinger, P. A., et al. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.2606-14.2015 · Cited by 123 · see citing works

Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor

Sherafat, A., Pfeiffer, F., Reiss, A., Wood, W. M., & Nishiyama, A. (2021) · Nature Communications · doi:10.1038/s41467-021-22532-2 · Cited by 122 · see citing works

Lineage, fate, and fate potential of NG2-glia

Nishiyama, A., Boshans, L. L., Gonçalves, C. M., Wegrzyn, J., & Patel, K. D. (2015) · Brain Research · doi:10.1016/j.brainres.2015.08.013 · Cited by 120 · see citing works

Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice

O’Shea, T. M., Ao, Y., Wang, S., Ren, Y., Cheng, A. L., Kawaguchi, R., Shi, Z., Swarup, V., & Sofroniew, M. V. (2024) · Nature Neuroscience · doi:10.1038/s41593-024-01684-6 · Cited by 123 · see citing works

NG2 cells (polydendrocytes): Listeners to the neural network with diverse properties

Hill, R., & Nishiyama, A. (2014) · Glia · doi:10.1002/glia.22664 · Cited by 117 · see citing works

Life-long oligodendrocyte development and plasticity

Nishiyama, A., Shimizu, T., Sherafat, A., & Richardson, W. D. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.02.004 · Cited by 114 · see citing works

Adult oligodendrocyte progenitor cells – Multifaceted regulators of the CNS in health and disease

Fernández-Castañeda, A., & Gaultier, A. (2016) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2016.01.005 · Cited by 111 · see citing works

DNA damage in the oligodendrocyte lineage and its role in brain aging

Tse, K.-H., & Herrup, K. (2017) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2016.05.006 · Cited by 108 · see citing works

NG2 cells (polydendrocytes) in brain physiology and repair

Nishiyama, A., Suzuki, R., & Zhu, X. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00133 · Cited by 108 · see citing works

A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging

Damisah, E. C., Hill, R., Тонг, Л., Murray, K. N., & Grutzendler, J. (2017) · Nature Neuroscience · doi:10.1038/nn.4564 · Cited by 107 · see citing works

Cell Lineage-Based Stratification for Glioblastoma

Wang, Z., Sun, D., Chen, Y.-J., Xie, X., Shi, Y., Tabar, V. S., Brennan, C. W., Bale, T., Jayewickreme, C. D., Laks, D. R., et al. (2020) · Cancer Cell · doi:10.1016/j.ccell.2020.06.003 · Cited by 108 · see citing works

Experimental Traumatic Brain Injury Identifies Distinct Early and Late Phase Axonal Conduction Deficits of White Matter Pathophysiology, and Reveals Intervening Recovery

Marion, C. M., Radomski, K. L., Cramer, N., Galdzicki, Z., & Armstrong, R. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.0819-18.2018 · Cited by 87 · see citing works

Striatal astrocytes produce neuroblasts in an excitotoxic model of Huntington's disease

Nato, G., Caramello, A., Trova, S., Avataneo, V., Rolando, C., Taylor, V., Buffo, A., Peretto, P., & Luzzati, F. (2015) · Development · doi:10.1242/dev.116657 · Cited by 103 · see citing works

Prolonged myelin deficits contribute to neuron loss and functional impairments after ischaemic stroke

Cheng, Y.-J., Wang, F., Feng, J., Yu, B., Wang, B., Gao, Q. C., Wang, T.-Y., Hu, B., Gao, X., Chen, J., et al. (2024) · Brain · doi:10.1093/brain/awae029 · Cited by 102 · see citing works

Understanding the NG2 Glial Scar after Spinal Cord Injury

Hackett, A. R., & Lee, J. K. (2016) · Frontiers in Neurology · doi:10.3389/fneur.2016.00199 · Cited by 103 · see citing works

Evidence for NG2-glia Derived, Adult-Born Functional Neurons in the Hypothalamus

Robins, S. C., Trudel, E., Rotondi, O., Liu, X., Djogo, T., Kryzskaya, D., Bourque, C. W., & Kokoeva, M. V. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078236 · Cited by 101 · see citing works

Cortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination

Call, C. L., & Bergles, D. E. (2021) · Nature Communications · doi:10.1038/s41467-021-25035-2 · Cited by 96 · see citing works

TGFα preserves oligodendrocyte lineage cells and improves white matter integrity after cerebral ischemia

Dai, X., Chen, J., Xu, F., Zhao, J., Cai, W., Sun, Z., Hitchens, T. K., Foley, L. M., Leak, R. K., Chen, J., et al. (2019) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x19830791 · Cited by 96 · see citing works

NG2 Cells Are Not a Major Source of Reactive Astrocytes After Neocortical Stab Wound Injury

Komitova, M., Serwanski, D., Lu, Q. R., & Nishiyama, A. (2011) · Glia · doi:10.1002/glia.21152 · Cited by 101 · see citing works

Conditional Deletion of the L-Type Calcium Channel Cav1.2 in Oligodendrocyte Progenitor Cells Affects Postnatal Myelination in Mice

Cheli, V., Santiago-González, D. S., Lama, T. N., Spreuer, V., Handley, V., Murphy, G. G., & Paez, P. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1770-16.2016 · Cited by 89 · see citing works

Robust and Fragile Aspects of Cortical Blood Flow in Relation to the Underlying Angioarchitecture

Shih, A. Y., Rühlmann, C., Blinder, P., Devor, A., Drew, P. J., Friedman, B., Knutsen, P. M., Lyden, P. D., Matéo, C., Mellander, L. J., et al. (2015) · Microcirculation · doi:10.1111/micc.12195 · Cited by 90 · see citing works

Restoring nuclear entry of Sirtuin 2 in oligodendrocyte progenitor cells promotes remyelination during ageing

Ma, X.-R., Zhu, X.-D., Xiao, Y.-J., Gu, H., Zheng, S.-S., Li, L., Wang, F., Dong, Z.-J., Wang, D.-X., Wu, Y., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28844-1 · Cited by 81 · see citing works

PDGFRβ-P2A-CreERT2 mice: a genetic tool to target pericytes in angiogenesis

Cuervo, H., Pereira, B., Nadeem, T., Lin, M., Lee, F., Kitajewski, J., & Lin, C. (2017) · Angiogenesis · doi:10.1007/s10456-017-9570-9 · Cited by 92 · see citing works

Myelin status and oligodendrocyte lineage cells over time after spinal cord injury: What do we know and what still needs to be unwrapped?

Pukos, N., Goodus, M. T., Sahinkaya, F. R., & McTigue, D. M. (2019) · Glia · doi:10.1002/glia.23702 · Cited by 94 · see citing works

Region and dynamic specificities of adult neural stem cells and oligodendrocyte precursors in myelin regeneration in the mouse brain

Brousse, B., Magalon, K., Durbec, P., & Cayre, M. (2015) · Biology Open · doi:10.1242/bio.012773 · Cited by 91 · see citing works

Diversity of Reactive Astrogliosis in CNS Pathology: Heterogeneity or Plasticity?

Moulson, A. J., Squair, J. W., Franklin, R. J. M., Tetzlaff, W., & Assinck, P. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.703810 · Cited by 90 · see citing works

Fate analysis of NG2 cells in vitro and in vivo

Zhu, X. (2009) · OpenCommons at University of Connecticut (University of Connecticut)

NG2 cells generate both oligodendrocytes and gray matter astrocytes

Zhu, X., Bergles, D. E., & Nishiyama, A. (2007) · Development · doi:10.1242/dev.004895 · Cited by 678 · see citing works

Early embryonic NG2 glia are exclusively gliogenic and do not generate neurons in the brain

Huang, W., Guo, Q., Bai, X., Scheller, A., & Kirchhoff, F. (2019) · Glia · doi:10.1002/glia.23590 · Cited by 39 · see citing works

NG2 cells generate oligodendrocytes and gray matter astrocytes in the spinal cord.

Zhu, X., Hill, R., & Nishiyama, A. (2008) · Neuron Glia Biology · doi:10.1017/s1740925x09000015 · Cited by 168 · see citing works

Novel NG2‐CreERT2 knock‐in mice demonstrate heterogeneous differentiation potential of NG2 glia during development

Huang, W., Zhao, N., Bai, X., Karram, K., Trotter, J., Goebbels, S., Scheller, A., & Kirchhoff, F. (2014) · Glia · doi:10.1002/glia.22648 · Cited by 177 · see citing works