Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
Bell, Robert D., Winkler, Ethan A., Singh, Itender, Sagare, Abhay P., Deane, Rashid, Wu, Zhenhua, Holtzman, David M., Betsholtz, Christer, Armulik, Annika, Sallstrom, Jan, Berk, Bradford C., Zlokovic, Berislav V.·2012·Nature
Cited by (1,002)
Items 101–200 of 1,002
- Cerebrovascular Effects of Apolipoprotein E: Implications for Alzheimer DiseaseZlokovic, Berislav V. · 2013 · JAMA Neurology
- Blood–Brain Barrier Breakdown: An Emerging Biomarker of Cognitive Impairment in Normal Aging and DementiaBasharat Hussain, Cheng Fang, Junlei Chang · 2021 · Frontiers in Neuroscience
- Plasma biomarkers of astrocytic and neuronal dysfunction in early‐ and late‐onset Alzheimer's diseaseFanny M. Elahi, Kaitlin Blackstone Casaletto, Renaud La Joie, Samantha M. Walters, Danielle Jenine Harvey, Amy A. Wolf, Lauren Edwards, Wilfredo Rivera Contreras, Anna Karydas, Yann Cobigo et al. · 2019 · Alzheimer s & Dementia
- Tight junction modulation of the blood brain barrier: CNS delivery of small moleculesChris Greene, Matthew Campbell · 2016 · Tissue Barriers
- The Microbiome and Disease: Reviewing the Links between the Oral Microbiome, Aging, and Alzheimer's DiseaseDeborah K. Shoemark, Shelley Jane Allen · 2014 · Journal of Alzheimer s Disease
- Cognitive decline in older adults with a history of traumatic brain injuryLaura Moretti, Irène Cristofori, Starla M. Weaver, Aileen Chau, Jaclyn N. Portelli Tremont, Jordan Henry Grafman · 2012 · The Lancet Neurology
- Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory CuesChen, Michelle B., Yang, Andrew C., Yousef, Hanadie, Lee, Davis, Chen, Winnie, Schaum, Nicholas, Lehallier, Benoit, Quake, Stephen R., Wyss-Coray, Tony · 2020 · Cell Reports
- Brain imaging of neurovascular dysfunction in Alzheimer’s diseaseMontagne, Axel, Nation, Daniel A., Pa, Judy, Sweeney, Melanie D., Toga, Arthur W., Zlokovic, Berislav V. · 2016 · Acta Neuropathologica
- Brain Microvascular Pericytes in Vascular Cognitive Impairment and DementiaMaiko T. Uemura, Takakuni Maki, Masafumi Ihara, Virginia M.‐Y. Lee, John Q. Trojanowski · 2020 · Frontiers in Aging Neuroscience
- Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotypeJanelidze, Shorena, Hertze, Joakim, Nägga, Katarina, Nilsson, Karin, Nilsson, Christer, Wennström, Malin, van Westen, Danielle, Blennow, Kaj, Zetterberg, Henrik, Hansson, Oskar · 2017 · Neurobiology of Aging
- Formation and maintenance of the BBBMarie Blanchette, Richard Daneman · 2015 · Mechanisms of Development
- Vascular contributions to cognitive impairment and dementia (VCID): A report from the 2018 National Heart, Lung, and Blood Institute and National Institute of Neurological Disorders and Stroke WorkshopBerislav V. Zloković, Rebecca F. Gottesman, Kenneth E. Bernstein, Sudha S. Seshadri, Ann Carolyn McKee, Heather M. Snyder, Steven Mark Greenberg, Kristine S. Yaffe, Chris B. Schaffer, Chun Yuan et al. · 2020 · Alzheimer s & Dementia
- Current understanding of the Alzheimer’s disease-associated microbiome and therapeutic strategiesDong-oh Seo, David M. Holtzman · 2024 · Experimental & Molecular Medicine
- Analysis of the brain mural cell transcriptomeHe, Liqun, Vanlandewijck, Michael, Raschperger, Elisabeth, Andaloussi Mäe, Maarja, Jung, Bongnam, Lebouvier, Thibaud, Ando, Koji, Hofmann, Jennifer, Keller, Annika, Betsholtz, Christer · 2016 · Scientific Reports
- Genetic predisposition, modifiable-risk-factor profile and long-term dementia risk in the general populationSilvan Licher, Shahzad Ahmad, Hata Karamujić‐Čomić, Trudy Voortman, Maarten J.G. Leening, M. Arfan Ikram, M. Kamran Ikram · 2019 · Nature Medicine
- The role of APOE in cerebrovascular dysfunctionTai, Leon M., Thomas, Riya, Marottoli, Felecia M., Koster, Kevin P., Kanekiyo, Takahisa, Morris, Alan W. J., Bu, Guojun · 2016 · Acta Neuropathologica
- Astrocyte-immune cell interactions in physiology and pathologyHan, Rafael T., Kim, Rachel D., Molofsky, Anna V., Liddelow, Shane A. · 2021 · Immunity
- Blood–Spinal Cord Barrier Pericyte Reductions Contribute to Increased Capillary PermeabilityWinkler, Ethan A, Sengillo, Jesse D, Bell, Robert D, Wang, Joseph, Zlokovic, Berislav V · 2012 · Journal of Cerebral Blood Flow & Metabolism
- The Neuroprotective Effects of Exercise: Maintaining a Healthy Brain Throughout AgingLaura Marie Vecchio, Ying Meng, Kristiana Xhima, Nir Lipsman, Clement Hamani, Isabelle Aubert · 2018 · Brain Plasticity
- Cerebral Blood Flow Measured by Arterial Spin Labeling MRI as a Preclinical Marker of Alzheimer's DiseaseChristina E. Wierenga, Chelsea C. Hays, Zvinka Z. Zlatar · 2014 · Journal of Alzheimer s Disease
- Systemic inflammation, blood-brain barrier vulnerability and cognitive/non-cognitive symptoms in Alzheimer disease: relevance to pathogenesis and therapyShuko Takeda, Naoyuki Sato, Ryuichi Morishita · 2014 · Frontiers in Aging Neuroscience
- Blood–spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model miceWinkler, Ethan A., Sengillo, Jesse D., Sagare, Abhay P., Zhao, Zhen, Ma, Qingyi, Zuniga, Edward, Wang, Yaoming, Zhong, Zhihui, Sullivan, John S., Griffin, John H. et al. · 2014 · Proceedings of the National Academy of Sciences
- Anesthesia and Surgery Impair Blood–Brain Barrier and Cognitive Function in MiceSiming Yang, Chang-ping Gu, Emiri T. Mandeville, Yuanlin Dong, Elga Esposito, Yiying Zhang, Guang Yang, Yuan Shen, Xiaobing Fu, Eng H. Lo et al. · 2017 · Frontiers in Immunology
- Consensus statement for diagnosis of subcortical small vessel diseaseGary A. Rosenberg, Anders Wallin, Joanna Marguerite Wardlaw, Hugh Stephen Markus, Joan Montaner, LESLIE I. WOLFSON, Costantino Iadecola, Berislav V. Zloković, Anne Joutel, Martin Dichgans et al. · 2015 · Journal of Cerebral Blood Flow & Metabolism
- Endothelial β-Catenin Signaling Is Required for Maintaining Adult Blood–Brain Barrier Integrity and Central Nervous System HomeostasisTran, Khiem A., Zhang, Xianming, Predescu, Dan, Huang, Xiaojia, Machado, Roberto F., Göthert, Joachim R., Malik, Asrar B., Valyi-Nagy, Tibor, Zhao, You-Yang · 2016 · Circulation
- Astrocyte Activation in Neurovascular Damage and Repair Following Ischaemic StrokeAdjanie Patabendige, Ayesha Singh, Stuart Iain Jenkins, Jon Sen, Ruoli Chen · 2021 · International Journal of Molecular Sciences
- APOE and Alzheimer’s Disease: Evidence Mounts that Targeting APOE4 may Combat Alzheimer’s PathogenesisUddin, Md. Sahab, Kabir, Md. Tanvir, Al Mamun, Abdullah, Abdel-Daim, Mohamed M., Barreto, George E., Ashraf, Ghulam Md · 2019 · Molecular Neurobiology
- Blood–Brain Barrier Breakdown in Alzheimer’s Disease: Mechanisms and Targeted StrategiesAlkhalifa, Amer E., Al-Ghraiybah, Nour F., Odum, Julia, Shunnarah, John G., Austin, Nataleigh, Kaddoumi, Amal · 2023 · International Journal of Molecular Sciences
- Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteinsHuynh, Tien-Phat V., Davis, Albert A., Ulrich, Jason D., Holtzman, David M. · 2017 · Journal of Lipid Research
- Pericyte Control of Blood Flow Across Microvascular Zones in the Central Nervous SystemDavid A. Hartmann, Vanessa Coelho‐Santos, Andy Y. Shih · 2021 · Annual Review of Physiology
- The blood–brain barrierBirgit Obermeier, Ajay Verma, Richard M. Ransohoff · 2016 · Handbook of clinical neurology
- Comorbidity of periodontal disease: two sides of the same coin? An introduction for the clinicianPalle Holmstrup, Christian Damgaard, Ingar Olsen, Björn Klinge, Allan Flyvbjerg, Claus Henrik Nielsen, Peter Riis Hansen · 2017 · Journal of Oral Microbiology
- Melatonin regulates Aβ production/clearance balance and Aβ neurotoxicity: A potential therapeutic molecule for Alzheimer’s diseaseYuanming Li, Jing Zhang, Jiale Wan, Anru Liu, Jinhao Sun · 2020 · Biomedicine & Pharmacotherapy
- Dual roles of astrocytes in plasticity and reconstruction after traumatic brain injuryYunxiang Zhou, Anwen Shao, Yihan Yao, Sheng Tu, Yongchuan Deng, Jianmin Zhang · 2020 · Cell Communication and Signaling
- Friends or foes: matrix metalloproteinases and their multifaceted roles in neurodegenerative diseasesBrkic, Marjana, Balusu, Sriram, Libert, Claude, Vandenbroucke, Roosmarijn E. · 2015 · Mediators of Inflammation
- HMGB1 and thrombin mediate the blood-brain barrier dysfunction acting as biomarkers of neuroinflammation and progression to neurodegeneration in Alzheimer’s diseaseFestoff, Barry W., Sajja, Ravi K., van Dreden, Patrick, Cucullo, Luca · 2016 · Journal of Neuroinflammation
- The impact of cerebrovascular aging on vascular cognitive impairment and dementiaTuo Yang, Yang Sun, Zhengyu Lu, Rehana K. Leak, Feng Zhang · 2016 · Ageing Research Reviews
- APOE4 derived from astrocytes leads to blood–brain barrier impairmentJackson, Rosemary J, Meltzer, Jonah C, Nguyen, Huong, Commins, Caitlin, Bennett, Rachel E, Hudry, Eloise, Hyman, Bradley T · 2022 · Brain
- Organ-specific protection mediated by cooperation between vascular and epithelial barriersIlaria Spadoni, Giulia Fornasa, María Rescigno · 2017 · Nature reviews. Immunology
- Retinoic Acid Induces Blood–Brain Barrier DevelopmentMizee, Mark R., Wooldrik, Desiree, Lakeman, Kim A. M., van het Hof, Bert, Drexhage, Joost A. R., Geerts, Dirk, Bugiani, Marianna, Aronica, Eleonora, Mebius, Reina E., Prat, Alexandre et al. · 2013 · The Journal of Neuroscience
- Oxidized cholesterol as the driving force behind the development of Alzheimer’s diseaseGamba, Paola, Testa, Gabriella, Gargiulo, Simona, Staurenghi, Erica, Poli, Giuseppe, Leonarduzzi, Gabriella · 2015 · Frontiers in Aging Neuroscience
- Modeling Sporadic Alzheimer's Disease in Human Brain Organoids under Serum ExposureChen, Xianwei, Sun, Guoqiang, Tian, E, Zhang, Mingzi, Davtyan, Hayk, Beach, Thomas G., Reiman, Eric M., Blurton‐Jones, Mathew, Holtzman, David M., Shi, Yanhong · 2021 · Advanced Science
- Cell type‐specific roles of APOE4 in Alzheimer diseaseBlumenfeld, Jessica, Yip, Oscar, Kim, Min Joo, Huang, Yadong · 2024 · Nature Reviews Neuroscience
- APOE2 enhances neuroprotection against Alzheimer’s disease through multiple molecular mechanismsConejero-Goldberg, C, Gomar, J J, Bobes-Bascaran, T, Hyde, T M, Kleinman, J E, Herman, M M, Chen, S, Davies, P, Goldberg, T E · 2014 · Molecular Psychiatry
- The capillary dysfunction hypothesis of Alzheimer's diseaseLeif Østergaard, Rasmus Aamand, Eugenio Gutiérrez‐Jiménez, Yi-Ching Lynn Ho, Jakob Udby Blicher, Søren Madsen, Kartheeban Nagenthiraja, Rikke Beese Dalby, Kim Ryun Drasbek, Arne Møller et al. · 2012 · Neurobiology of Aging
- Age-Associated Changes in the Immune System and Blood–Brain Barrier FunctionsMichelle A. Erickson, William A. Banks · 2019 · International Journal of Molecular Sciences
- Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsinKim, Hyosung, Leng, Kun, Park, Jinhee, Sorets, Alexander G., Kim, Suil, Shostak, Alena, Embalabala, Rebecca J., Mlouk, Kate, Katdare, Ketaki A., Rose, Indigo V. L. et al. · 2022 · Nature Communications
- Lack of Widespread BBB Disruption in Alzheimer’s Disease Models: Focus on Therapeutic AntibodiesBien-Ly, Nga, Boswell, C. Andrew, Jeet, Surinder, Beach, Thomas G., Hoyte, Kwame, Luk, Wilman, Shihadeh, Vera, Ulufatu, Sheila, Foreman, Oded, Lu, Yanmei et al. · 2015 · Neuron
- Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID‐19 pandemic, now and in the futureVincent Mok, Sarah Tamsin Pendlebury, Adrian Wong, Suvarna Alladi, Lisa Wing Chi Au, Philip M. Bath, Geert Jan Biessels, Christopher Chen, Charlotte Cordonnier, Martin Dichgans et al. · 2020 · Alzheimer s & Dementia
- Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer’s disease: the role, regulation and restoration of LRP1Ramanathan, Anita, Nelson, Amy R., Sagare, Abhay P., Zlokovic, Berislav V. · 2015 · Frontiers in Aging Neuroscience
- Higher Aortic Stiffness Is Related to Lower Cerebral Blood Flow and Preserved Cerebrovascular Reactivity in Older AdultsAngela Lee Jefferson, Francis E. Cambronero, Dandan Liu, Elizabeth E. Moore, Jacquelyn E. Neal, James Greg Terry, Sangeeta Nair, Kimberly R. Pechman, Swati Rane, L. Taylor Davis et al. · 2018 · Circulation
- APOE4 is associated with cognitive and pathological heterogeneity in patients with Alzheimer’s disease: a systematic reviewSheina Emrani, Hirra A. Arain, Cassandra A. DeMarshall, Tal Nuriel · 2020 · Alzheimer s Research & Therapy
- Cellular and molecular mechanisms of the blood–brain barrier dysfunction in neurodegenerative diseasesTongli Chen, Yan Dai, Chenghao Hu, Zihao Lin, Shengzhe Wang, Jing Yang, Linghui Zeng, Shanshan Li, Weiyun Li · 2024 · Fluids and Barriers of the CNS
- Multifaceted roles of APOE in Alzheimer diseaseJackson, Rosemary J., Hyman, Bradley T., Serrano-Pozo, Alberto · 2024 · Nature Reviews Neurology
- Vascular Degeneration in Parkinson's DiseaseGuan, Jian, Pavlovic, Darja, Dalkie, Nicholas, Waldvogel, Henry J., O'Carroll, Simon J., Green, Colin R., Nicholson, Louise F.B. · 2013 · Brain Pathology
- Multifaceted Role of Matrix Metalloproteinases in Neurodegenerative Diseases: Pathophysiological and Therapeutic PerspectivesTapan Behl, Gagandeep Kaur, Aayush Sehgal, Shaveta Bhardwaj, Sukhbir Singh, Camelia Liana Buhaș, Claudia Teodora Judea Pusta, Diana Uivaroșan, Mihai Alexandru Munteanu, SIMONA GABRIELA BUNGAU · 2021 · International Journal of Molecular Sciences
- Targeting Oxidative Stress and Inflammatory Response for Blood–Brain Barrier Protection in Intracerebral HemorrhageShengpan Chen, Lingzhi Li, Chao Peng, Chunjing Bian, Pınar Eser Ocak, John H. Zhang, Yong Yang, Dong Zhou, Guangzhong Chen, Yumin Luo · 2022 · Antioxidants and Redox Signaling
- Targeting microglia for the treatment of Alzheimer’s DiseaseWes, Paul D., Sayed, Faten A., Bard, Frédérique, Gan, Li · 2016 · Glia
- Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse BrainHudry, Eloise, Dashkoff, Jonathan, Roe, Alysson D., Takeda, Shuko, Koffie, Robert M., Hashimoto, Tadafumi, Scheel, Maria, Spires-Jones, Tara, Arbel-Ornath, Michal, Betensky, Rebecca et al. · 2013 · Science Translational Medicine
- Astrocyte Involvement in Blood–Brain Barrier Function: A Critical Update Highlighting Novel, Complex, Neurovascular InteractionsDoina Ramona Manu, MARK A. SLEVIN, Laura Bărcuţean, Timea Forró, Tudor‐Gabriel Boghițoiu, Rodica Bălașa · 2023 · International Journal of Molecular Sciences
- Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular PathologyHansang Cho, Ji Hae Seo, Keith H.K. Wong, Yasukazu Terasaki, Joseph Park, Kiwan Bong, Ken Arai, Eng H. Lo, Daniel Irimia · 2015 · Scientific Reports
- Pericytes as Inducers of Rapid, Matrix Metalloproteinase-9-Dependent Capillary Damage during IschemiaRobert G. Underly, Manuel S. Levy, David A. Hartmann, Roger I. Grant, Ashley N. Watson, Andy Y. Shih · 2016 · Journal of Neuroscience
- Cerebral Microvascular Injury: A Potentially Treatable Endophenotype of Traumatic Brain Injury-Induced NeurodegenerationDanielle K. Sandsmark, Asma Bashir, Cheryl Lea Wellington, Ramon R. Diaz-Arrastia · 2019 · Neuron
- Oligodendrocyte Precursor Cells Support Blood-Brain Barrier Integrity via TGF-β SignalingJi Hae Seo, Takakuni Maki, Mitsuyo Maeda, Nobukazu Miyamoto, Anna C. Liang, Kazuhide Hayakawa, Loc−Duyen D. Pham, Fumihiko Suwa, Akihiko Taguchi, Tomohiro Matsuyama et al. · 2014 · PLoS ONE
- Can oral infection be a risk factor for Alzheimer's disease?Ingar Olsen, Sim K. Singhrao · 2015 · Journal of Oral Microbiology
- PKM2 promotes neutrophil activation and cerebral thromboinflammation: therapeutic implications for ischemic strokeNirav Dhanesha, Rakesh B. Patel, Prakash Doddapattar, Madankumar Ghatge, Gagan D. Flora, Manish Kumar Jain, Daniel R. Thedens, Heena M. Olalde, Mariia Kumskova, Enrique C. C Leira et al. · 2021 · Blood
- Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive functionKoizumi, Kenzo, Hattori, Yorito, Ahn, Sung Ji, Buendia, Izaskun, Ciacciarelli, Antonio, Uekawa, Ken, Wang, Gang, Hiller, Abigail, Zhao, Lingzhi, Voss, Henning U. et al. · 2018 · Nature Communications
- Lymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer’s Disease?Antoine Louveau, Sandro Dá Mesquita, Jonathan Kipnis · 2016 · Neuron
- Reactive astrocytes: The nexus of pathological and clinical hallmarks of Alzheimer’s diseaseBrittani R. Price, Lance A. Johnson, Christopher Mark Norris · 2021 · Ageing Research Reviews
- APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-βMontagne, Axel, Nikolakopoulou, Angeliki M., Huuskonen, Mikko T., Sagare, Abhay P., Lawson, Erica J., Lazic, Divna, Rege, Sanket V., Grond, Alexandra, Zuniga, Edward, Barnes, Samuel R. et al. · 2021 · Nature Aging
- Higher risk of dementia in English older individuals who are overweight or obeseYixuan Ma, Olesya Ajnakina, Andrew Steptoe, Dorina Cadar · 2020 · International Journal of Epidemiology
- Blood-Brain Barrier Breakdown after Embolic Stroke in Rats Occurs without Ultrastructural Evidence for Disrupting Tight JunctionsMartin Krueger, Wolfgang Härtig, Andreas Reichenbach, Ingo Bechmann, Dominik Michalski · 2013 · PLoS ONE
- Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s diseaseTosha Williams, David Borchelt, Paramita Chakrabarty · 2020 · Molecular Neurodegeneration
- Cerebral Edema in Traumatic Brain InjuryEthan A. Winkler, Daniel J. Minter, John K. Yue, Geoffrey T. Manley · 2016 · Neurosurgery Clinics of North America
- Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular functionLiu, Chia-Chen, Zhao, Jing, Fu, Yuan, Inoue, Yasuteru, Ren, Yingxue, Chen, Yuanxin, Doss, Sydney V., Shue, Francis, Jeevaratnam, Suren, Bastea, Ligia et al. · 2022 · Nature Neuroscience
- The isolation and molecular characterization of cerebral microvesselsYun-Kyoung Lee, Hiroki Uchida, Helen K. Smith, Akira Ito, Teresa Sánchez · 2019 · Nature Protocols
- APOE‐modulated Aβ‐induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspectiveTai, Leon M., Ghura, Shivesh, Koster, Kevin P., Liakaite, Vaiva, Maienschein‐Cline, Mark, Kanabar, Pinal, Collins, Nicole, Ben‐Aissa, Manel, Lei, Arden Zhengdeng, Bahroos, Neil et al. · 2015 · Journal of Neurochemistry
- Heart failure and Alzheimer′s diseasePavla Čermáková, Maria Eriksdotter, Lars H. Lund, Bengt G. Winblad, Piotr Religa, Dorota Religa · 2014 · Journal of Internal Medicine
- Association Between Midlife Risk Factors and Late-Onset EpilepsyEmily L. Johnson, Gregory L. Krauss, Alexandra K. Lee, Andrea L.C. Schneider, Jennifer L. Dearborn, Anna Kucharska‐Newton, Juebin Huang, Álvaro Alonso, Rebecca F. Gottesman · 2018 · JAMA Neurology
- ApoE4 upregulates the activity of mitochondria‐associated ER membranesTambini, Marc D, Pera, Marta, Kanter, Ellen, Yang, Hua, Guardia‐Laguarta, Cristina, Holtzman, David, Sulzer, David, Area‐Gomez, Estela, Schon, Eric A · 2016 · The EMBO Reports
- Apolipoprotein E as a Therapeutic Target in Alzheimer’s Disease: A Review of Basic Research and Clinical EvidenceYu Yamazaki, Meghan M. Painter, Guojun Bu, Takahisa Kanekiyo · 2016 · CNS Drugs
- LRP1 activation attenuates white matter injury by modulating microglial polarization through Shc1/PI3K/Akt pathway after subarachnoid hemorrhage in ratsJianhua Peng, Jinwei Pang, Lei Huang, Budbazar Enkhjargal, Tongyu Zhang, Jun Mo, Pei Wu, Weilin Xu, Yuchun Zuo, Jun Peng et al. · 2019 · Redox Biology
- Human Apolipoprotein E ε4 Expression Impairs Cerebral Vascularization and Blood—Brain Barrier Function in MiceWaël Alata, Yue Ye, Isabelle St‐Amour, Milène Vandal, Frédéric Calon · 2014 · Journal of Cerebral Blood Flow & Metabolism
- Apolipoprotein E and Alzheimer's diseaseBenjamin Troutwine, Laylan Hamid, Colton R Lysaker, Taylor A. Strope, Heather Wilkins · 2021 · Acta Pharmaceutica Sinica B
- Toward more predictive genetic mouse models of Alzheimer’s diseaseOnos, Kristen D., Sukoff Rizzo, Stacey J., Howell, Gareth R., Sasner, Michael · 2016 · Brain Research Bulletin
- Intracellular Cholesterol Trafficking and Impact in NeurodegenerationFabián Arenas, Carmen García‐Ruiz, José Carlos Fernández-Checa · 2017 · Frontiers in Molecular Neuroscience
- Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injuryYoon Kyung Choi, Takakuni Maki, Emiri T. Mandeville, Seong‐Ho Koh, Kazuhide Hayakawa, Ken Arai, Young‐Myeong Kim, Michael J. Whalen, Changhong Xing, Xiaoying Wang et al. · 2016 · Nature Medicine
- Alzheimer’s Disease Pathogenesis: Role of Autophagy and Mitophagy Focusing in MicrogliaEshraghi, Mehdi, Adlimoghaddam, Aida, Mahmoodzadeh, Amir, Sharifzad, Farzaneh, Yasavoli-Sharahi, Hamed, Lorzadeh, Shahrokh, Albensi, Benedict C., Ghavami, Saeid · 2021 · International Journal of Molecular Sciences
- Plasma levels of apolipoprotein Eand risk of dementia in the general populationRasmussen, Katrine L., Tybjærg‐Hansen, Anne, Nordestgaard, Børge G., Frikke‐Schmidt, Ruth · 2015 · Annals of Neurology
- Cellular cholesterol homeostasis and Alzheimer’s diseaseChang, Ta-Yuan, Yamauchi, Yoshio, Hasan, Mazahir T., Chang, Catherine · 2017 · Journal of Lipid Research
- Rapamycin rescues vascular, metabolic and learning deficits in apolipoprotein E4 transgenic mice with pre-symptomatic Alzheimer’s diseaseAi‐Ling Lin, Jordan B. Jahrling, Wei Zhang, Nicholas DeRosa, Vikas Bakshi, Peter Romero, Verónica Galván, Arlan G Richardson · 2015 · Journal of Cerebral Blood Flow & Metabolism
- Astrocyte alterations in neurodegenerative pathologies and their modeling in human induced pluripotent stem cell platformsMinna Oksanen, Šárka Lehtonen, Merja Jaronen, Gundars Goldsteins, Riikka H. Hämäläinen, Jari Koıstınaho · 2019 · Cellular and Molecular Life Sciences
- The Important Interface Between Apolipoprotein E and Neuroinflammation in Alzheimer’s DiseaseKloske, Courtney M., Wilcock, Donna M. · 2020 · Frontiers in Immunology
- Biomarkers used in Alzheimer’s disease diagnosis, treatment, and preventionMahaman, Yacoubou Abdoul Razak, Embaye, Kidane Siele, Huang, Fang, Li, Longfei, Zhu, Feiqi, Wang, Jian-Zhi, Liu, Rong, Feng, Jun, Wang, Xiaochuan · 2022 · Ageing Research Reviews
- Blood–brain barrier link to human cognitive impairment and Alzheimer’s diseaseBarisano, Giuseppe, Montagne, Axel, Kisler, Kassandra, Schneider, Julie A., Wardlaw, Joanna M., Zlokovic, Berislav V. · 2022 · Nature Cardiovascular Research
- FACS isolation of endothelial cells and pericytes from mouse brain microregionsElizabeth Erin Crouch, Fiona K. Doetsch · 2018 · Nature Protocols
- Using the zebrafish model for Alzheimer’s disease researchMorgan Newman, Esmaeil Ebrahimie, Michael T. Lardelli · 2014 · Frontiers in Genetics
- Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosisLastres-Becker, Isabel, Innamorato, Nadia G., Jaworski, Tomasz, Rábano, Alberto, Kügler, Sebastian, Van Leuven, Fred, Cuadrado, Antonio · 2014 · Brain
- Noninvasive and targeted delivery of therapeutics to the brain using focused ultrasoundCharissa Poon, Dallan McMahon, Kullervo Hynynen · 2016 · Neuropharmacology
- In vitro modeling of the neurovascular unit: advances in the fieldAditya Bhalerao, Farzane Sivandzade, Sabrina Rahman Archie, Ekram Ahmed Chowdhury, Behnam Noorani, Luca Cucullo · 2020 · Fluids and Barriers of the CNS