Astrocyte scar formation aids central nervous system axon regeneration

G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences

Faul, F., Erdfelder, E., Lang, A.-G., & Buchner, A. (2007) · Behavior Research Methods · doi:10.3758/bf03193146 · Cited by 65,971

STAR: ultrafast universal RNA-seq aligner

Dobin, A., Davis, C. A., Schlesinger, F., Drenkow, J., Zaleski, C., Jha, S., Batut, P., Chaisson, M., & Gingeras, T. R. (2013) · Bioinformatics · doi:10.1093/bioinformatics/bts635 · Cited by 51,709

<tt>edgeR</tt> : a Bioconductor package for differential expression analysis of digital gene expression data

Robinson, M. D., McCarthy, D. J., & Smyth, G. K. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btp616 · Cited by 41,364

HTSeq—a Python framework to work with high-throughput sequencing data

Anders, S., Pyl, P. T., & Huber, W. (2015) · Bioinformatics · doi:10.1093/bioinformatics/btu638 · Cited by 21,464

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

Madisen, L., Zwingman, T. A., Sunkin, S. M., Oh, S. W., Zariwala, H. A., Gu, H., Ng, L. L., Palmiter, R. D., Hawrylycz, M. J., Jones, A. R., et al. (2010) · Nature Neuroscience · doi:10.1038/nn.2467 · Cited by 6,907

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

Zhang, Y., Chen, K., Sloan, S. A., Bennett, M. L., Scholze, A. R., O'Keeffe, S., Phatnani, H. P., Guarnieri, P., Caneda, C., Ruderisch, N., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1860-14.2014 · Cited by 4,875

Regeneration beyond the glial scar

Silver, J., & Miller, J. H. (2004) · Nature reviews. Neuroscience · doi:10.1038/nrn1326 · Cited by 3,151

Degeneration and Regeneration of the Nervous System.

(1929) · JAMA · doi:10.1001/jama.1929.02710220063037 · Cited by 2,908

Genomic analysis of reactive astrogliosis

Zamanian, J. L., Xu, L., Foo, L. C., Nouri, N., Zhou, L., Giffard, R. G., & Barres, B. A. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.6221-11.2012 · Cited by 2,404

Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats

David, S., & Aguayo, A. J. (1981) · Science · doi:10.1126/science.6171034 · Cited by 1,698

Safety and Efficacy of Rose Bengal Derivatives for Glial Scar Ablation in Chronic Spinal Cord Injury

Patil, N., Truong, V., Holmberg, M. H., Lavoie, N., McCoy, M. R., Dutton, J. R., Holmberg, E. G., & Parr, A. M. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2017.5398 · Cited by 24

Crosstalk between soluble PDGF‐BB and PDGFRβ promotes astrocytic activation and synaptic recovery in the hippocampus after subarachnoid hemorrhage

Zhou, X., Wu, Q., Lu, Y., Zhang, X., Lv, S., Shao, J., Zhou, Y., Chen, J., Hou, L., Huang, C., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201900195r · Cited by 24

Mitochondrial spongiotic brain disease: astrocytic stress and harmful rapamycin and ketosis effect

Ignatenko, O., Nikkanen, J., Kononov, A., Zamboni, N., Ince-Dunn, G., & Suomalainen, A. (2020) · Life Science Alliance · doi:10.26508/lsa.202000797 · Cited by 22

LAR inhibitory peptide promotes recovery of diaphragm function and multiple forms of respiratory neural circuit plasticity after cervical spinal cord injury

Cheng, L., Sami, A., Ghosh, B., Urban, M. W., Heinsinger, N. M., Liang, S. S., Smith, G. M., Wright, M. C., Li, S., & Lepore, A. C. (2020) · Neurobiology of Disease · doi:10.1016/j.nbd.2020.105153 · Cited by 26

Comparison of the effects of two therapeutic strategies based on olfactory ensheathing cell transplantation and repetitive magnetic stimulation after spinal cord injury in female mice

Delarue, Q., Robac, A., Massardier, R., Marie, J., & Guérout, N. (2021) · Journal of Neuroscience Research · doi:10.1002/jnr.24836 · Cited by 22

Long non-coding RNA: An underlying bridge linking neuroinflammation and central nervous system diseases

Chen, Z., Wu, H., & Zhang, M. (2021) · Neurochemistry International · doi:10.1016/j.neuint.2021.105101 · Cited by 24

Astrogliosis in juvenile non-human primates 2 years after infant anaesthesia exposure

Neudecker, V., Perez‐Zoghbi, J. F., Martin, L. D., Dissen, G. A., Grafe, M. R., & Brambrink, A. M. (2021) · British Journal of Anaesthesia · doi:10.1016/j.bja.2021.04.034 · Cited by 25

Intramuscular insulin-like growth factor-1 gene therapy modulates reactive microglia after traumatic brain injury

Herrera, M. L., Feijóo‐Bandín, S., Champarini, L. G., Hereñú, C. B., & Bellini, M. J. (2021) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2021.07.023 · Cited by 24

Tumor necrosis factor (TNF) induces astrogliosis, microgliosis and promotes survival of cortical neurons

Abd‐El‐Basset, E. M., Rao, M. S. R., Alshawaf, S. M., Ashkanani, H. K. A. H. A., & Kabli, A. H. (2021) · AIMS neuroscience · doi:10.3934/neuroscience.2021031 · Cited by 24

The role of astrocytes in prion-like mechanisms of neurodegeneration

Smethurst, P., Franklin, H., Clarke, B. E., Sidle, K. C. L., & Patani, R. (2021) · Brain · doi:10.1093/brain/awab366 · Cited by 25

Integrin Signaling in the Central Nervous System in Animals and Human Brain Diseases

Ikeshima-Kataoka, H., Sugimoto, C., & Tsubokawa, T. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031435 · Cited by 24

Injury programs shape glioblastoma

Brooks, L. J., Ragdale, H. S., Hill, C. S., Clements, M., & Parrinello, S. (2022) · Trends in Neurosciences · doi:10.1016/j.tins.2022.08.006 · Cited by 22

STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease

Hagemann, T. L., Coyne, S., Levin, A., Wang, L., Feany, M. Β., & Messing, A. (2023) · Cells · doi:10.3390/cells12070978 · Cited by 24

Hydrogen sulfide inhibits lipopolysaccharide-based neuroinflammation-induced astrocyte polarization after cerebral ischemia/reperfusion injury

Li, X., Yin, X., Pang, J., Chen, Z., & Wen, J. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.175743 · Cited by 24

Glial progenitor heterogeneity and key regulators revealed by single-cell RNA sequencing provide insight to regeneration in spinal cord injury

Wei, H., Wu, X., Withrow, J. S., Durán, R. C., Singh, S. X., Chaboub, L. S., Rakshit, J., Mejia, J., Rolfe, A., Herrera, J. J., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112486 · Cited by 23

Biology-driven material design for ischaemic stroke repair

Phan, N. V., Rathbun, E. M., Ouyang, Y., Carmichael, S. T., & Segura, T. (2023) · Nature Reviews Bioengineering · doi:10.1038/s44222-023-00117-6 · Cited by 26

Anti-inflammatory properties of the glial scar

Coulson‐Thomas, V. J., Gesteira, T. F., & Coulson‐Thomas, Y. M. (2016) · Neural Regeneration Research · doi:10.4103/1673-5374.194710 · Cited by 24

Involvement of Astrocytes in Mediating the Central Effects of Ghrelin

Frago, L. M., & Chowen, J. A. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18030536 · Cited by 24

MicroRNA-21a-5p promotes fibrosis in spinal fibroblasts after mechanical trauma

Wang, W., Tang, S., Li, H., Liu, R., Su, Y., Shen, L., Sun, M., & Ning, B. (2018) · Experimental Cell Research · doi:10.1016/j.yexcr.2018.06.002 · Cited by 24

Sprouty2—a Novel Therapeutic Target in the Nervous System?

Hausott, B., & Klimaschewski, L. P. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1338-8 · Cited by 24

Modern approaches to investigating non‐neuronal aspects of Alzheimer's disease

Liddelow, S. A. (2019) · The FASEB Journal · doi:10.1096/fj.201802592 · Cited by 26

Engineering biomaterial microenvironments to promote myelination in the central nervous system

Unal, D. B., Caliari, S. R., & Lampe, K. J. (2019) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2019.07.013 · Cited by 24

Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area

Xu, Y., Zhu, Z.-H., Xu, X., Sun, H., Zheng, H.-M., Zhang, J., Wang, H., Fang, J.-W., Liu, Y., Huang, L., et al. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03341-8 · Cited by 22

Calming the Nerves via the Immune Instructive Physiochemical Properties of Self‐Assembling Peptide Hydrogels

Mahmoudi, N., Mohamed, E., Dehnavi, S. S., Aguilar, L. M. C., Harvey, A. R., Parish, C. L., Williams, R. J., & Nisbet, D. R. (2023) · Advanced Science · doi:10.1002/advs.202303707 · Cited by 23

Evaluating the in vivo glial response to miniaturized parylene cortical probes coated with an ultra-fast degrading polymer to aid insertion

Lo, M.-C., Wang, S., Singh, S., Damodaran, V. B., Ahmed, I., Coffey, K. R., Barker, D., Saste, K., Kals, K., Kaplan, H. M., et al. (2018) · Journal of Neural Engineering · doi:10.1088/1741-2552/aa9fad · Cited by 22

Novel cytokine-loaded PCL-PEG scaffold composites for spinal cord injury repair

Wang, P., Wang, H., Ma, K., Wang, S., Yang, C., Mu, N., Yang, F., Feng, H., & Chen, T. (2020) · RSC Advances · doi:10.1039/c9ra10385f · Cited by 23

Neural circuit repair after central nervous system injury

Tsujioka, H., & Yamashita, T. (2020) · International Immunology · doi:10.1093/intimm/dxaa077 · Cited by 24

EphA4 Obstructs Spinal Cord Neuron Regeneration by Promoting Excessive Activation of Astrocytes

Chen, X., Zhang, L., Fu, H., Yu, Z., Liu, H., & Wang, S. (2021) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-021-01046-x · Cited by 24

Long-term monitoring of chronic demyelination and remyelination in a rat ischemic stroke model using macromolecular proton fraction mapping

Khodanovich, M. Y., Gubskiy, I. L., Kudabaeva, M., Namestnikova, D. D., Kisel, A. A., Anan’ina, T. V., Tumentceva, Y. A., Mustafina, L. R., & Yarnykh, V. L. (2021) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x211020860 · Cited by 24

Cathepsin H deficiency decreases hypoxia-ischemia-induced hippocampal atrophy in neonatal mice through attenuated TLR3/IFN-β signaling

Ni, J., Zhao, J., Zhang, X., Reinheckel, T., Türk, V., & Nakanishi, H. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02227-7 · Cited by 23

An Insight into Molecular Targets of Breast Cancer Brain Metastasis

Kaleem, M., Dalhat, M. H., Azmi, L., Asar, T. O., Ahmad, W., Alghanmi, M. S., Almostadi, A., Zughaibi, T. A., & Tabrez, S. S. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911687 · Cited by 23

Ginsenoside Rg1 promotes astrocyte‐to‐neuron transdifferentiation in rat and its possible mechanism

Shen, K., Wu, D., Sun, B., Zhu, Y., Wang, H., Zou, W., Ma, Y., & Lu, Z. (2022) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14000 · Cited by 23

Inflammatory stimulation of astrocytes affects the expression of miRNA-22-3p within NSCs-EVs regulating remyelination by targeting KDM3A

Han, T., Song, P., Wu, Z., Wang, C., Liu, Y., Wang, Y., Li, K., & Shen, C. (2023) · Stem Cell Research & Therapy · doi:10.1186/s13287-023-03284-w · Cited by 24

Advances in the study of the molecular biological mechanisms of radiation-induced brain injury.

Chen, G., Li, W. J., Xu, J., Pang, L., Tang, L., Yu, S., Li, A., Ge, H., Huang, R., & Cheng, H. (2023) · PubMed Central · Cited by 24

Neuronal Replenishment via Hydrogel-Rationed Delivery of Reprogramming Factors

Mahmoudi, N., Wang, Y., Moriarty, N., Ahmed, N. Y., Dehorter, N., Lisowski, L., Harvey, A. R., Parish, C. L., Williams, R. J., & Nisbet, D. R. (2024) · ACS Nano · doi:10.1021/acsnano.3c11337 · Cited by 23

The nature of early astroglial protection—Fast activation and signaling

Kardos, J., Héja, L., Jemnitz, K., Kovács, R., & Palkovits, M. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2017.03.005 · Cited by 23

Fibrin functionalization with synthetic adhesive ligands interacting with α6β1 integrin receptor enhance neurite outgrowth of embryonic stem cell-derived neural stem/progenitors

Silva, J., Bento, A. R., Barros, D., Laundos, T. L., Sousa, S. R., Quelhas, P., Sousa, M. M., Pêgo, A. P., & Amaral, I. F. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.07.013 · Cited by 25

Regenerative potential of primary adult human neural stem cells on micropatterned bio-implants boosts motor recovery

Davoust, C., Plas, B., Béduer, A., Demain, B., Salabert, A., Sol, J. C., Christophe Vieu, A., Vaysse, L., & Loubinoux, I. (2017) · Stem Cell Research & Therapy · doi:10.1186/s13287-017-0702-3 · Cited by 23

C57BL/6 and Swiss Webster Mice Display Differences in Mobility, Gliosis, Microcavity Formation and Lesion Volume After Severe Spinal Cord Injury

Noristani, H. N., They, L., & Perrin, F. E. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00173 · Cited by 23

Activation of Neurogenesis in Multipotent Stem Cells Cultured In Vitro and in the Spinal Cord Tissue After Severe Injury by Inhibition of Glycogen Synthase Kinase-3

Rodríguez-Jiménez, F. J., Vilches, A., Aragó, M. A. P., Clemente, E., Román, R., Leal, J., Artero‐Castro, A., Fustero, S., Moreno‐Manzano, V., Jendelová, P., et al. (2020) · Neurotherapeutics · doi:10.1007/s13311-020-00928-0 · Cited by 23

Deletion or Inhibition of Astrocytic Transglutaminase 2 Promotes Functional Recovery after Spinal Cord Injury

Elahi, A., Emerson, J., Rudlong, J., Keillor, J. W., Salois, G., Visca, A., Girardi, P., Johnson, G. V. W., & Pröschel, C. (2021) · Cells · doi:10.3390/cells10112942 · Cited by 23

Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytesPreprint

Li, J., Pan, L., Godoy, M. I., Pembroke, W. G., Rexach, J. E., Condro, M. C., Alvarado, A. G., Harteni, M., Chen, Y.-W., Stiles, L., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.17.044222 · Cited by 23

Progression of reactive gliosis and astroglial phenotypic changes following stab wound‐induced traumatic brain injury in mice

Cieri, M. B., Villarreal, A., Cuautle, D. G., Mailing, I., & Ramos, A. J. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15941 · Cited by 23

Corticospinal tract: a new hope for the treatment of post-stroke spasticity

Huang, L., Yi, L., Huang, H., Zhan, S., Chen, R., & Yue, Z. (2023) · Acta Neurologica Belgica · doi:10.1007/s13760-023-02377-w · Cited by 28

Inhibition of CD44 suppresses the formation of fibrotic scar after spinal cord injury via the JAK2/STAT3 signaling pathway

Guo, J., Yang, T., Zhang, W., Yu, K., Xu, X., Li, W., Song, L., Gu, X., Cao, R., & Cui, S. (2024) · iScience · doi:10.1016/j.isci.2024.108935 · Cited by 23

Ginsenoside Rg1 regulates astrocytes to promote angiogenesis in spinal cord injury via the JAK2/STAT3 signaling pathway

Yin, S., Xia, F., Zou, W., Jiang, F., Shen, K., Sun, B., & Lu, Z. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118531 · Cited by 22

Targeting astrocytes polarization after spinal cord injury: a promising direction

Li, H., Liu, Y., Sun, Y., Guo, H., Lv, S., Guo, W., Ren, J., Wang, Y., Zu, J., Yan, J., et al. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1478741 · Cited by 22

Current advances in in vitro models of central nervous system trauma

Omelchenko, A., Singh, N. K., & Firestein, B. L. (2020) · Current Opinion in Biomedical Engineering · doi:10.1016/j.cobme.2020.05.002 · Cited by 22

Thermosensitive quaternized chitosan hydrogel scaffolds promote neural differentiation in bone marrow mesenchymal stem cells and functional recovery in a rat spinal cord injury model

Huang, C. X., Liu, Y., Ding, J., Dai, Y.-P., Le, L., Wang, L., Ding, E., & Yang, J. (2021) · Cell and Tissue Research · doi:10.1007/s00441-021-03430-x · Cited by 22

The Gliopeptide ODN, a Ligand for the Benzodiazepine Site of GABA A Receptors, Boosts Functional Recovery after Stroke

Lamtahri, R., Hazime, M., Gowing, E. K., Nagaraja, R. Y., Maucotel, J., Alasoadura, M., Quilichini, P., Lehongre, K., Lefranc, B., Gach, K., et al. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.2255-20.2021 · Cited by 24

Thrombin induces morphological and inflammatory astrocytic responses via activation of PAR1 receptor

Chen, X., Zhang, H., Hao, H., Zhang, X., Song, H., He, B., Wang, Y., Zhou, Y., Zhu, Z., Hu, Y., et al. (2022) · Cell Death Discovery · doi:10.1038/s41420-022-00997-4 · Cited by 23

Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content with potential relevance to inflammation and recovery processes

Bub, A., Brenna, S., Alawi, M., Kügler, P., Gui, Y., Kretz, O., Altmeppen, H. C., Magnus, T. U., & Puig, B. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04357-4 · Cited by 21

Ectoderm-derived frontal bone mesenchymal stem cells promote traumatic brain injury recovery by alleviating neuroinflammation and glutamate excitotoxicity partially via FGF1

Qin, Q., Wang, T., Xu, Z., Liu, S., Zhang, H., Du, Z., Wang, J., Wang, Y., Wang, Z., Yuan, S., et al. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-03032-6 · Cited by 22

Rho Kinase Inhibitor Y27632 Improves Recovery After Spinal Cord Injury by Shifting Astrocyte Phenotype and Morphology via the ROCK/NF-κB/C3 Pathway

Zhang, Y., Wang, X., Jiang, C. Q., Chen, Z., Ni, S., Fan, H., Wang, Z., Tian, F., An, J., Yang, H., et al. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03756-0 · Cited by 22

Bridging the gap of axonal regeneration in the central nervous system: A state of the art review on central axonal regeneration

da Costa, G., Ribeiro, F. F., Sebastião, A. M., Muir, E. M., & Vaz, S. H. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1003145 · Cited by 23

Scorpion venom peptide HsTx2 suppressed PTZ-induced seizures in mice via the circ_0001293/miR-8114/TGF-β2 axis

Hu, Y. W., Meng, B., Yin, S., Yang, M., Li, Y., Liu, N., Li, S., Liu, Y., Sun, D., Wang, S., et al. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02647-z · Cited by 22

Single-cell transcriptome reveals diversity of Müller cells with different metabolic-mitochondrial signatures in normal and degenerated macula

Liu, B., He, J., Zhong, L., Huang, L., Gong, B., Hu, J., Qian, H., & Yang, Z. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1079498 · Cited by 22

Photobiomodulation inhibits the expression of chondroitin sulfate proteoglycans after spinal cord injury via the Sox9 pathway

Zhang, Z., Song, Z., Luo, L., Zhu, Z., Zuo, X., Ju, C., Wang, X., Ma, Y., Wu, T., Yao, Z., et al. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.374136 · Cited by 22

The Role and Therapeutic Implications of Inflammation in the Pathogenesis of Brain Arteriovenous Malformations

Ricciardelli, A., Robledo, A., Fish, J. E., Kan, P. T. M., Harris, T. H., & Wythe, J. D. (2023) · Biomedicines · doi:10.3390/biomedicines11112876 · Cited by 24

Synergistic Pharmacological Therapy to Modulate Glial Cells in Spinal Cord Injury

Veneruso, V., Petillo, E., Pizzetti, F., Orro, A., Comolli, D., Paola, M. D., Verrillo, A., Baggiolini, A., Votano, S., Castiglione, F., et al. (2023) · Advanced Materials · doi:10.1002/adma.202307747 · Cited by 22

Extracellular matrix constitution and function for tissue regeneration and repair

Caldeira, J., Sousa, A., Sousa, D. M., & Barros, D. (2017) · Elsevier eBooks · doi:10.1016/b978-0-08-100803-4.00002-4 · Cited by 24

RNA Nanotherapeutics for the Amelioration of Astroglial Reactivity

Smith, J. A., Braga, A., Verheyen, J., Basilico, S., Bandiera, S., Alfaro‐Cervelló, C., Peruzzotti‐Jametti, L., Shu, D., Haque, F., Guo, P., et al. (2017) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2017.11.008 · Cited by 22

Assembly and repair of eye-to-brain connections

Varadarajan, S. G., & Huberman, A. D. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.10.001 · Cited by 23

Endothelin-1 stimulates expression of cyclin D1 and S-phase kinase–associated protein 2 by activating the transcription factor STAT3 in cultured rat astrocytes

Kōyama, Y., Sumie, S., Nakano, Y., Nagao, T., Tokumaru, S., & Michinaga, S. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.005614 · Cited by 24

Inhibitory milieu at the multiple sclerosis lesion site and the challenges for remyelination

Galloway, D. A., Gowing, E., Setayeshgar, S., & Kothary, R. (2019) · Glia · doi:10.1002/glia.23711 · Cited by 23

Spatiotemporal distribution of chondroitin sulfate proteoglycans after optic nerve injury in rodents

Pearson, C. S., Solano, A. G., Tilve, S. M., Mencio, C. P., Martin, K. R. G., & Geller, H. M. (2019) · Experimental Eye Research · doi:10.1016/j.exer.2019.107859 · Cited by 23

Melatonin exerts neuroprotective effects by attenuating astro- and microgliosis and suppressing inflammatory response following spinal cord injury

Yang, Z., Bao, Y., Chen, W., & He, Y. (2019) · Neuropeptides · doi:10.1016/j.npep.2019.102002 · Cited by 22

An injectable recombinant human milk fat globule–epidermal growth factor 8–loaded copolymer system for spinal cord injury reduces inflammation through NF-κB and neuronal cell death

Gong, Z., Wang, C., Ni, L., Ying, L., Shu, J., Wang, J., Yu, C., Xia, K., Cheng, F., Shi, K., et al. (2020) · Cytotherapy · doi:10.1016/j.jcyt.2020.01.016 · Cited by 22

Inhibition of phosphodiesterase IV enzyme improves locomotor and sensory complications of spinal cord injury via altering microglial activity: Introduction of Roflumilast as an alternative therapy

Moradi, K., Golbakhsh, M., Haghighi, F., Afshari, K., Nikbakhsh, R., Khavandi, M. M., Faghani, S., Badripour, A., Etemadi, A., Ashraf‐Ganjouei, A., et al. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.106743 · Cited by 22

Neuroprotective effects of matrix metalloproteinases in cerebral ischemic rats by promoting activation and migration of astrocytes and microglia

Zhang, X., Zhao, H., Li, D., & Li, H.-P. (2018) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2018.11.003 · Cited by 22

A spatiotemporal molecular atlas of mouse spinal cord injury identifies a distinct astrocyte subpopulation and therapeutic potential of IGFBP2

Wang, Z., Li, Z., Luan, T., Cui, G., Shu, S., Liang, Y., Zhang, K., Xiao, J., Yu, W., Cui, J., et al. (2024) · Developmental Cell · doi:10.1016/j.devcel.2024.06.016 · Cited by 22

Exosomes: a promising microenvironment modulator for spinal cord injury treatment

Ma, Y., Yu, X., Pan, J., Wang, Y., Li, R., Wang, X., Hu, H., & Hao, D. (2025) · International Journal of Biological Sciences · doi:10.7150/ijbs.115242 · Cited by 21

Different roles of astrocytes in the blood–brain barrier during the acute and recovery phases of stroke

Cheng, J., Zheng, Y., Cheng, F., Wang, C., Han, J., Zhang, H., Lan, X., Zhang, C., Wang, X., Wang, Q., et al. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-01417 · Cited by 24

Points regarding cell transplantation for the treatment of spinal cord injury

Idé, C., & Kanekiyo, K. (2016) · Neural Regeneration Research · doi:10.4103/1673-5374.187021 · Cited by 21

Astrocyte phenotypes: Emphasis on potential markers in neuroinflammation.

Bozic, I. D., Savić, D. Z., & Lavrnja, I. C. (2021) · PubMed · doi:10.14670/hh-18-284 · Cited by 22

Interleukin-17A regulates ependymal cell proliferation and functional recovery after spinal cord injury in mice

Miyajima, H., Itokazu, T., Tanabe, S., & Yamashita, T. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-04064-1 · Cited by 23

Principles of Astrogliopathology

Verkhratsky, A., Li, B., Scuderi, C., & Parpura, V. (2021) · Advances in Neurobiology · doi:10.1007/978-3-030-77375-5_3 · Cited by 21

Tenascin-C restricts reactive astrogliosis in the ischemic brain

Dzyubenko, E., Manrique‐Castano, D., Pillath‐Eilers, M., Vasileiadou, P., Reinhard, J., Faissner, A., & Hermann, D. M. (2022) · Matrix Biology · doi:10.1016/j.matbio.2022.04.003 · Cited by 21

Remimazolam induced cognitive dysfunction in mice via glutamate excitotoxicity

Zhou, X., Zhang, C., Wang, L., & Jin, S. (2022) · Translational Neuroscience · doi:10.1515/tnsci-2022-0220 · Cited by 21

Maf1 is an intrinsic suppressor against spontaneous neural repair and functional recovery after ischemic stroke

Tsang, C. K., Mi, Q.-J., Su, G., Lee, G. H., Xie, X., D’Arcangelo, G., Huang, L., & Zheng, X. F. S. (2022) · Journal of Advanced Research · doi:10.1016/j.jare.2022.11.007 · Cited by 21

Restoration of spinal cord injury: From endogenous repairing process to cellular therapy

Wu, Y., Tang, Z., Zhang, J., Wang, Y., & Liu, S. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.1077441 · Cited by 21

Post-injury born oligodendrocytes incorporate into the glial scar and contribute to the inhibition of axon regeneration

Xing, J., Rheaume, B. A., Kim, J., Łukomska, A., Sajid, M. S., Damania, A., & Trakhtenberg, E. F. (2023) · Development · doi:10.1242/dev.201311 · Cited by 22

3D bioprinting approaches for spinal cord injury repair

Jiu, J., Liu, H., Li, D., Li, J., Liu, L., Yang, W., Yan, L., Li, S., Zhang, J., Li, X., et al. (2024) · Biofabrication · doi:10.1088/1758-5090/ad3a13 · Cited by 22

Increase of aquaporin 9 expression in astrocytes participates in astrogliosis

Hirt, L., Price, M., Mastour, N., Brunet, J., Barrière, G., Friscourt, F., & Badaut, J. (2017) · Journal of Neuroscience Research · doi:10.1002/jnr.24061 · Cited by 21

Effect of CLIP3 Upregulation on Astrocyte Proliferation and Subsequent Glial Scar Formation in the Rat Spinal Cord via STAT3 Pathway After Injury

Chen, X., Cheng Ann, C. H. E. N., Hao, J., Zhang, J., & Zhang, F. (2017) · Journal of Molecular Neuroscience · doi:10.1007/s12031-017-0998-6 · Cited by 21

RIC3, the cholinergic anti-inflammatory pathway, and neuroinflammation

Ben‐David, Y., Kagan, S., Ben-Ami, H. C., Rostami, J., Mizrahi, T., Kulkarni, A., Thakur, G. A., Vaknin‐Dembinsky, A., Healy, L. M., Brenner, T., et al. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.106381 · Cited by 22

Determining the effect of aging, recovery time, and post-stroke memantine treatment on delayed thalamic gliosis after cortical infarct

Kim, G. S., Stephenson, J. M., Mamun, A. A., Wu, T., Goss, M. G., Min, J., Li, J., Liu, F., & Marrelli, S. P. (2021) · Scientific Reports · doi:10.1038/s41598-021-91998-3 · Cited by 23

Niche Cells Crosstalk In Neuroinflammation After Traumatic Brain Injury

Jia, Y., Wang, G., Ye, Y., Kang, E., Chen, H., Guo, Z., & He, X. (2020) · International Journal of Biological Sciences · doi:10.7150/ijbs.52169 · Cited by 20

Epigenetic and epitranscriptomic regulation of axon regeneration

Cheng, Y., Song, H., Ming, G., & Weng, Y. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02028-9 · Cited by 21

Transplanting Human Neural Stem Cells with ≈50% Reduction of SOX9 Gene Dosage Promotes Tissue Repair and Functional Recovery from Severe Spinal Cord Injury

Liu, J. A., Tam, K. W., Chen, Y. L., Feng, X., Chan, C. W. L., Lo, A. L. H., Wu, K. L., Hui, M., Wu, M., Chan, K. K., et al. (2023) · Advanced Science · doi:10.1002/advs.202205804 · Cited by 20

HIF ‐1α promotes astrocytic production of macrophage migration inhibitory factor following spinal cord injury

Hao, H., Hou, Y., Li, A., Niu, L., Li, S., He, B., Zhang, X., Song, H., Cai, R., Zhou, Y., et al. (2023) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14300 · Cited by 20

Chloride co‐transporters as possible therapeutic targets for stroke

Baudel, M. A. S. M., Poole, A. V., & Darlison, M. G. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13901 · Cited by 17

The Function of FGFR1 Signalling in the Spinal Cord: Therapeutic Approaches Using FGFR1 Ligands after Spinal Cord Injury

Haenzi, B., & Moon, L. D. F. (2017) · Neural Plasticity · doi:10.1155/2017/2740768 · Cited by 20

Longitudinal Magnetic Resonance Imaging Analysis and Histological Characterization after Spinal Cord Injury in Two Mouse Strains with Different Functional Recovery: Gliosis as a Key Factor

Noristani, H. N., Saint-Martin, G., Cardoso, M., Sidi‐Boulenouar, R., Catteau, M., Coillot, C., Goze‐Bac, C., & Perrin, F. E. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2017.5613 · Cited by 20

The role of transglutaminase 2 in mediating glial cell function and pathophysiology in the central nervous system

Rudlong, J., Cheng, A., & Johnson, G. V. W. (2019) · Analytical Biochemistry · doi:10.1016/j.ab.2019.113556 · Cited by 20

Coniferyl Aldehyde Inhibits the Inflammatory Effects of Leptomeningeal Cells by Suppressing the JAK2 Signaling

Wang, Y., Gao, Y., Li, X., Sun, X., Wang, Z., Wang, H., Nie, R., Yu, W., & Zhou, Y. (2020) · BioMed Research International · doi:10.1155/2020/4616308 · Cited by 21

Induced pluripotent stem cell technology for spinal cord injury: a promising alternative therapy

Shen, P., Wang, B., & Li, Y. (2021) · Neural Regeneration Research · doi:10.4103/1673-5374.303013 · Cited by 20

Astrocytes in Neurodegenerative Diseases: A Perspective from Tauopathy and α-Synucleinopathy

Wang, P., & Ye, Y. (2021) · Life · doi:10.3390/life11090938 · Cited by 21

Progress in research into spinal cord injury repair: Tissue engineering scaffolds and cell transdifferentiation

Ma, C., Zhang, P., & Shen, Y. (2019) · Journal of Neurorestoratology · doi:10.26599/jnr.2019.9040024 · Cited by 19

Not everything is scary about a glial scar

Liddelow, S. A., & Barres, B. A. (2016) · Nature · doi:10.1038/nature17318 · Cited by 51

The astrocytic scar facilitates axon regeneration in the CNS, contrary to accepted wisdom

Wood, H. B. (2016) · Nature Reviews Neurology · doi:10.1038/nrneurol.2016.60

Not such a scar on regrowth

Yates, D. M. (2016) · Nature reviews. Neuroscience · doi:10.1038/nrn.2016.54

The complex contribution of the astrocyte scar

Fitzgerald, M. (2016) · Neural Regeneration Research · doi:10.4103/1673-5374.187023 · Cited by 2

The astrocyte scar – not so inhibitory after all?

Tang, B. (2016) · Neural Regeneration Research · doi:10.4103/1673-5374.187024 · Cited by 5