Cited by 1,261Gut microbiota and healthAsthma and respiratory diseasesNutritional Studies and Diet

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Diet, gut microbiota and immune responses

Maslowski, Kendle M, Mackay, Charles R·2011·Nature Immunology

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Abstract

The fields of immunology, microbiology, nutrition and metabolism are rapidly converging. Here we expand on a diet-microbiota model as the basis for the greater incidence of asthma and autoimmunity in developed countries.

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Crossref · 10.1038/ni0111-5

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Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
Frank, D. N., St. Amand, A. L., Feldman, R. A., Boedeker, E. C., Harpaz, N., & Pace, N. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706625104 · Cited by 4,611
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Oh, D. Y., Talukdar, S., Bae, E. J., Imamura, T., Morinaga, H., Fan, W., Li, P., Lu, W. J., Watkins, S. M., & Olefsky, J. M. (2010) · Cell · doi:10.1016/j.cell.2010.07.041 · Cited by 2,428
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Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study
Patterson, C. C., Dahlquist, G. G., Gyürüs, E., Green, A., & Soltész, G. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60568-7 · Cited by 1,854
Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation
Le Poul, E., Loison, C., Struyf, S., Springael, J.-Y., Lannoy, V., Decobecq, M.-E., Brezillon, S., Dupriez, V., Vassart, G., Van Damme, J., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301403200 · Cited by 1,651

Show all 29 references

Research works printed but not linked: 1

Vaahtovuo, J. et al. J. Rheumatol. 35, 1500–1505 (2008).

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References
Shaw, C. A. (2017) · Wiley eBooks · doi:10.1002/9781118634523.refs · Cited by 9
Effects of alginate oligosaccharides on the growth performance, immunity, and intestinal health of the hybrid grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatu ♂)
An, S., Lin, Z., Han, L., Xun, P., Zhou, C., Guo, R., Lin, H., & Yu, W. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.144422 · Cited by 4
Differences of the 6N and 6J Substrains of C57BL/6 Mice in the Development of Experimental Autoimmune Encephalomyelitis
Álvarez‐López, A. I., Ponce‐España, E., Cruz‐Chamorro, I., Santos‐Sánchez, G., Bejarano, I., Álvarez‐Sánchez, N., Lardone, P. J., & Carrillo‐Vico, A. (2025) · MedComm · doi:10.1002/mco2.70228 · Cited by 4
Effect of In Vitro Colonic Fermentation on the Physicochemical, Structural, and Prebiotic Properties of Ultrasound-H₂O₂ Degraded Brassica Rapa L. Polysaccharides
Guo, D., Lei, J., Mu, W., Hua, J., Liu, J., Liu, C., & Qian, H. (2025) · Food and Bioprocess Technology · doi:10.1007/s11947-025-04171-3 · Cited by 4
“Studies have shown that plant-derived polysaccharides can modulate the composition and activity of gut microbiota, enhancing SCFAs production and thereby supporting immune function, anti-inflammatory responses, and overall metabolic balance (Chen et al. 2022a, b; Maslowski & Mackay, 2011).”
Carrier-free supramolecular architectonics of quercetin–berberine for safety-redefined therapy of ulcerative colitis
Zhang, X., Fu, Y., Liu, S., Zhang, J., Xu, F., Zhang, C., Wang, Y., & Huo, C. (2026) · Materials Today Bio · doi:10.1016/j.mtbio.2026.102970 · Cited by 4
“Notably, Bacillota are major producers of short-chain fatty acids, and their reduced abundance may impair epithelial nutrition and immune modulation [ 55 – 57 ] .”
Glyphosate-Based Herbicides and Their Potential Impact on the Microbiota of Social Bees
Muñoz, J. P., Soto-Jiménez, D., Brito, A., & Quezada‐Romegialli, C. (2025) · Toxics · doi:10.3390/toxics13070551 · Cited by 4
“In particular, this microbial imbalance can impair key physiological processes such as immune defense, development, and nutrition [86].”
High-Fiber Diets in Gastrointestinal Tract Diseases
Silveira, A. L. M., Ferreira, A. V. M., & Teixeira, M. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814468-8.00019-3 · Cited by 4
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Gely, C., Gordillo, J., Bertoletti, F., González‐Muñoza, C., López, A., & García-Planella, E. (2022) · Gastroenterología y Hepatología · doi:10.1016/j.gastrohep.2022.10.005 · Cited by 4
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He, T., & Qian, W. (2024) · Zeitschrift für Rheumatologie · doi:10.1007/s00393-024-01480-4 · Cited by 4
Lacticaseibacillus paracasei completely utilizes fructooligosacchrides in the human gut through β-fructosidase (FosE)
Jung, D.-H., Kim, I.-Y., Kim, Y., Chung, W., Lim, M.-Y., Nam, Y., Seo, D., & Park, C. (2024) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-024-04068-x · Cited by 4
“Moreover, the gut microbiota plays a vital role in maintaining host health through nutrient absorption, immunomodulation, and disease control by interacting with the host, particularly with epithelial and immune cells (Kogut and Arsenault 2016; Maslowski and Mackay 2011).”
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Senaprom, S., Namjud, N., Ondee, T., Bumrungpert, A., & Pongpirul, K. (2024) · Nutrients · doi:10.3390/nu16223933 · Cited by 5
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He, Y., Zhang, Z., Jiang, H., Meenu, M., Zhou, Q., Ding, W., Yang, H., & Liu, Y. (2025) · Aquaculture Reports · doi:10.1016/j.aqrep.2025.102819 · Cited by 4
Ultraprocessed Grains and Risk of Inflammatory Bowel Disease: Results From the Prospective Urban Rural Epidemiology Study
Narula, N., Wong, E. C. L., Mente, A., Rangarajan, S., Lang, X., Li, Q., Chen, M., Mohan, I., Nasir, N. M., Díaz, M. L., et al. (2025) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000003700 · Cited by 4
Microbiota intestinal en salud y enfermedad
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Calenge, F., Martin, C., Floc'H, N. L., Phocas, F., Morgavi, D. P., Rogel-Gaillard, C., & Quéré, P. (2014) · INRAE Productions Animales · doi:10.20870/productions-animales.2014.27.3.3068 · Cited by 4
Autoimmunity
Kono, D. H., & Theofilopoulos, A. N. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-31696-5.00019-x · Cited by 4
Cross Talk Between Functional Foods and Gut Health
Thakur, K., Zhang, J., Wei, Z., Kumar, N., Tomar, S. K., & Pophaly, S. D. (2017) · Advances in human services and public health (AHSPH) book series · doi:10.4018/978-1-5225-2970-5.ch009 · Cited by 4
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Shukla, R., Ruwali, M., Pawar, N. S., & Flora, S. J. S. (2020) · Springer eBooks · doi:10.1007/978-981-15-8214-1_13 · Cited by 4
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Background
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BackgroundMethod
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de Figueiredo, F. C., & Neto, P. D. O. (2022) · Clean Energy Production Technologies · doi:10.1007/978-981-16-3682-0_10 · Cited by 4
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Hrnčíř, T., Krejsek, J., Šplı́chal, I., & Hrnčíř, T. (2014) · Acta Medica (Hradec Kralove Czech Republic) · doi:10.14712/18059694.2014.46 · Cited by 4
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Background
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Brandtzaeg, P. (2013) · Elsevier eBooks · doi:10.1533/9780857095749.1.34 · Cited by 4
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Nawaz, A., Batool, H., Kashif, M., Abbas, A., Shahzad, F., Tahir, R., & Afzal, N. (2019) · Bangladesh Journal of Medical Science · doi:10.3329/bjms.v18i3.41622 · Cited by 4
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Kar, S. K. (2017) · doi:10.18174/416108 · Cited by 4
Seasonal diets overwhelm host species in shaping the gut microbiota of Yak and Tibetan sheepPreprint
Wei, X., Cheng, F., Shi, H., Zhou, X., Li, B., Wang, L., Wang, W., & Zhang, J. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/481374 · Cited by 4
“In the recent decade, intensive studies indicated that there are many factors can shape the 50 composition of gut microbiota in mammals, including host genetics and diet [3-8].”
Background
Gut commensal Lactobacillus strain induces a balanced trained immunity phenotype to enhance vaccine efficacy through JAK-STAT-SOCS pathway
Niu, L., Li, H., Guo, J., Jia, Z., Chang, Q., Liu, N., Zhang, S., & Ge, J. (2025) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-025-10769-y · Cited by 3
“Since the 1960s, with the establishment of germ-free animal models and the discovery of the gut-associated immune system, research into the interactions between gut microbiota and the human immune system has gradually garnered attention [1–4].”
Specific prebiotics improved growth, pathogen inhibition and short-chain fatty acids production by probiotic bacilli: Screening synbiotic combinations for aquaculture
Sukul, T., Acharya, D., & Ghosh, K. (2025) · The Microbe · doi:10.1016/j.microb.2025.100634 · Cited by 3
Thyroid–Microbiome Allostasis and Mitochondrial Performance: An Integrative Perspective in Exercise Physiology
Odriozola-Martínez, A., González, A., Odriozola, I., Corbi, F., & Álvarez‐Herms, J. (2025) · Nutrients · doi:10.3390/nu18010059 · Cited by 3
“Immune correlates include low-grade inflammation and redox imbalance, often associated with decreased SCFA production and gut dysbiosis [26,44].”
Influential
Dietary powder and molecular imprinted polymer nanoencapsulated sodium propionate to enhance growth performance, digestive enzymes activity, antioxidant defense, and mucosal immune response in African cichlid ( Labidochromis lividus ) fingerlings
Sarkheil, M., Safari, O., & Kordestani, D. (2023) · Annals of Animal Science · doi:10.2478/aoas-2022-0074 · Cited by 3
Protective Effects of Influenza Vaccine against Colorectal Cancer in Populations with Chronic Kidney Disease: A Nationwide Population-Based Cohort Study
Chen, C., Hao, W., Hong, H.-J., Lin, K.-J., Chiu, C.-C., Yang, T.-Y., Fang, Y.-A., Jian, W., Chen, M., Hsu, M., et al. (2023) · Cancers · doi:10.3390/cancers15082398 · Cited by 3
“Drug intake (antibiotics, iron supplements, and polymer phosphate binders) and diet (decreased fiber intake) are also critical factors that change the composition of the microbiome community in the gut [26].”
Background
The gut microbiota improves reproductive dysfunction in obese mice by suppressing the NLRP3/ASC/caspase-1 axis
Huang, H., Zhou, T., He, F., Wen, B., Yang, Y., Zhong, W., Wang, Q., & Li, J. (2024) · Future Microbiology · doi:10.1080/17460913.2024.2386867 · Cited by 4
Fecal fatty acid-linked bile acid profiles in pediatric patients with ulcerative colitis
Suzuki, H., Suzuki, M., Jimbo, K., Hibio, M., Sasaki, T., Murai, T., Yamashita, Y., Une, M., Ogawa, S., Okamoto, T., et al. (2024) · Clinica Chimica Acta · doi:10.1016/j.cca.2024.120060 · Cited by 3
County-Level Food Insecurity and Hepatocellular Carcinoma Risk: A Cross-Sectional Analysis
Kehm, R. D., Vilfranc, C. L., McDonald, J. A., & Wu, H.-C. (2025) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph22010120 · Cited by 3
The essential role of prebiotics in restoring gut health in long COVID
Rubio‐Casillas, A., Rodríguez-Quintero, C. M., Hromić-Jahjefendić, A., Uversky, V. N., Redwan, E. M. M. M., & Brogna, C. (2025) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2025.01.004 · Cited by 3
Microbiome and Metabolome Alterations in Nrf2 Knockout Mice With Induced Gut Inflammation and Fed With Phenethyl Isothiocyanate and Cranberry Enriched Diets
Yin, R., Sargsyan, D., Wu, R., Hudlikar, R. R., Li, S. N., Kuo, H. D., Sarwar, M. S., Zhou, Y., Gao, Z., Howell, A. B., et al. (2025) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.70283 · Cited by 3
“The role of the gut microbiome has been a focal point of many studies over the past several decades, with its potential beneficial effects in metabolizing essential nutrients, providing energy, and enhancing the immune system [3, 4, 66].”
Targeting the microbiota in the management of gastrointestinal and liver disease.
Quigley, E. M. M., & Monsour, H. (2013) · PubMed · doi:10.47892/rgp.2013.332.219 · Cited by 3
Drosophila–Acetobacter as a Model System for Understanding Animal–Microbiota Interactions
Kim, S., Lee, K., Park, D. Y., Jang, I.-H., & Lee, W. (2016) · Springer eBooks · doi:10.1007/978-4-431-55933-7_6 · Cited by 3
Combination of a Lactobacillus-Based Probiotic and Organic Acids Decrease Egg to Chick Weight Loss and Reduce Salmonella spp. Counts in the Litter of Commercial Broiler Breeders
Michel, M. A., Revidatti, F. A. R., Fernández, R. J., Sindik, M. L. M., Sanz, P., Hernández-Velasco, X., Latorre, J. D., Hargis, B. M., & Téllez‐Isaías, G. (2019) · Food and Nutrition Sciences · doi:10.4236/fns.2019.108072 · Cited by 3
Helminths and intestinal microbiota interaction: role in the development of noncommunicable diseases
Sokolova, Т. S., Fedorova, O. S., Saltykova, I. V., Petrov, V. A., Fedotova, M. M., Kovshirina, Y. V., Деев, И. А., & Ogorodova, L. M. (2019) · Bulletin of Siberian Medicine · doi:10.20538/1682-0363-2019-3-214-225 · Cited by 3
Diversity of growth performance and rumen microbiota vary with feed types
Du, S., Bu, Z., You, S., Bao, J. R., & Jia, Y. (2022) · Frontiers in Sustainable Food Systems · doi:10.3389/fsufs.2022.1004373 · Cited by 3
“Indeed, the different substrates of the diet affect the growth of rumen microbiota (Maslowski and Mackay, 2011; Li et al., 2012; Kasparovska et al., 2016).”
Background
Oral intake of heat-killed Lactiplantibacillus pentosus ONRICb0240 partially protects mice against SARS-CoV-2 infection
Kiso, M., Uraki, R., Ito, M., Yamayoshi, S., Kotani, Y., Imai, M., Kohda, N., & Kawaoka, Y. (2023) · Frontiers in Virology · doi:10.3389/fviro.2023.1137133 · Cited by 3
The Mediterranean Diet
Caprara, G. (2023) · Nutrition and health · doi:10.1007/978-3-031-24663-0_16 · Cited by 3
Dietary Fibre Consumption in a Sample of Italian Adults: Relationship Between Dietary Habits and Gender, Ponderal Status and Physical Activity
Galfo, M., Maccati, F., Melini, F., & Melini, V. (2023) · Journal of Health Science and Medical Research · doi:10.31584/jhsmr.20231011 · Cited by 3
[Specific changes in gut microbiota and short-chain fatty acid levels in infants with cow's milk protein allergy].
Yu, Z., Yue, L.-L., Wang, Z.-H., Wang, R.-Z., Li, L., Zhang, W.-C., & Li, X. (2024) · PubMed Central · doi:10.7499/j.issn.1008-8830.2308007 · Cited by 3
Immunostimulatory effects of dietary verjuice (Vitis vinifera) on immune response and transcription of immune-related genes in juvenile rainbow trout (Oncorhynchus mykiss)
Mostafavi, Z. S., Shekarabi, S. P. H., Mehrgan, M. S., Islami, H. R., Yılmaz, E., & Nazari, K. (2024) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2024.109714 · Cited by 3
Dietary therapy of murine primary biliary cholangitis induces hepatocellular steatosis: A cautionary tale
Zhang, W., Tekreeti, T. A., Leung, P. S. C., Tsuneyama, K., Dhillon, H., Rojas, M., Heuer, L. S., Ridgway, W. M., Ansari, A. A., Young, H. A., et al. (2024) · Liver International · doi:10.1111/liv.16060 · Cited by 3
“21,22 26 In this study, we investigated whether a dietary regimen of supplementing normal chow with 15% propionylated high-amylose maize starch (HAMSP) would influence the disease course, using the ARE-Del model of autoimmune cholangitis.”
Correlations between Lumbricus terrestris survival and gut microbiota
Rudi, K., & Strætkvern, K. O. (2012) · Microbial Ecology in Health and Disease · doi:10.3402/mehd.v23i0.17316 · Cited by 3
“T he interaction between the host and its gut microbiota is of fundamental importance for host health and disease (1).”
Background
Metabonomics and Gut Microbial Paradigm in Healthy Aging
Biagi, E., Candela, M., Martin, F., Collino, S., Franceschi, C., & Brigidi, P. (2014) · Molecular and integrative toxicology · doi:10.1007/978-1-4471-6539-2_9 · Cited by 3
Advances in Nutrition of Patients with Inflammatory Bowel Diseases
Dworzanski, T., & Celiński, K. (2016) · Journal of Nutrition & Food Sciences · doi:10.4172/2155-9600.1000451 · Cited by 3
“The fibre after fermentation is metabolised by intestinal bacteria to short-chain fatty acids inhibiting the transcription factor involved in the production of proinflammatory cytokines [10].”
Background
Beneficial effectiveness of probiotic-low-fat ice cream containing Krueo Ma Noy (Cissampelos pareira L.) gum on colon microbiome under a dynamic gut model
Kemsawasd, V., & Chaikham, P. (2019) · Food Research · doi:10.26656/fr.2017.3(5).068 · Cited by 3
“Clear correlations between increased levels of beneficial gut bacteria and organic acids (Table 3) in the simulated gastrointestinal environment can be explained by their immunemodulatory and regulative functions, and natural inhibitory effects of common gut pathogens, including Staphylococcus aureus, Clostridium botu…”
Background
Microbiota: Current Research and Emerging Trends
Salazar, N., González Solares, S., Nogacka, A., Rios-Covián, D., Arboleya, S., Fernández, M. G., & González de los Reyes-Gavilán, C. (2018) · Caister Academic Press eBooks · doi:10.21775/9781910190937 · Cited by 3
Cancer and Immunology-the Homeostasis Dance
Ekine-Afolabi, B. A. (2022) · Journal of Modern Medical Oncology · doi:10.53964/jmmo.2022005 · Cited by 3
“Gut microbiota are extension of self (individual) and this together with genetic make-up, are determinant of metabolism and physiology of an individual([6]).”
Background

Authors: Maslowski, K. M., & Mackay, C. R.
Affiliations: Garvan Institute of Medical Research (AU)
Monash University (AU)
Corresponding author: Mackay, Charles R
ORCID: Maslowski, Kendle M
Mackay, Charles R
Venue: Nature Immunology
Publisher: Springer Science and Business Media LLC
Published: 2010-12-17
Volume: 12
Issue: 1
Pages: 5-9
ISSN: 1529-2908 (ISSN-L)
1529-2916
DOI: 10.1038/ni0111-5
OpenAlex: W1988821718
Cited by: 1,261
References: 29
Citations by year: 2026: 23 · 2025: 53 · 2024: 60 · 2023: 102 · 2022: 98 · 2021: 114 · 2020: 99 · 2019: 115 · 2018: 81 · 2017: 95 · 2016: 88 · 2015: 82 · 2014: 87 · 2013: 73 · 2012: 55
FWCI: 21.25
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature Immunology (publishedVersion)
PubMed (publishedVersion)
Helmholtz Centre for Ocean Research Kiel (GEOMAR) (acceptedVersion)
University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Keywords: diet, gut microbiota, immune response, asthma, autoimmunity, nutrition and immunity, host-microbe interactions, developed countries
MeSH terms: Animals, Clinical Trials as Topic, Diet, Humans, Inflammation, Signal Transduction, Models, Immunological, Immunity, Mucosal, Genetic Predisposition to Disease, Gastrointestinal Tract, Lipid Metabolism, Mice, Metagenome, Immunomodulation

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