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Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

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MasterCARD: a priceless link to innate immunity

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Identification of Host Cytosolic Sensors and Bacterial Factors Regulating the Type I Interferon Response to Legionella pneumophila

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Response of host inflammasomes to viral infection

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Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease

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Ubiquitination in the antiviral immune response

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Key Role of Ubc5 and Lysine-63 Polyubiquitination in Viral Activation of IRF3

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Cytosolic 5′-Triphosphate Ended Viral Leader Transcript of Measles Virus as Activator of the RIG I-Mediated Interferon Response

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The IKK-related kinases: from innate immunity to oncogenesis

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TRIM26 Negatively Regulates Interferon-β Production and Antiviral Response through Polyubiquitination and Degradation of Nuclear IRF3

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DHX9 Pairs with IPS-1 To Sense Double-Stranded RNA in Myeloid Dendritic Cells

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Cleavage of the Adaptor Protein TRIF by Enterovirus 71 3C Inhibits Antiviral Responses Mediated by Toll-Like Receptor 3

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Cytosolic Double-Stranded RNA Activates the NLRP3 Inflammasome via MAVS-Induced Membrane Permeabilization and K+ Efflux

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Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids

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Pattern recognition receptors: A contemporary view on liver diseases

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Innate Immune Evasion Strategies of Influenza Viruses

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IL-21 and T follicular helper cells

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Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2

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Glycogen Synthase Kinase 3β Regulates IRF3 Transcription Factor-Mediated Antiviral Response via Activation of the Kinase TBK1

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Virus-Infection or 5′ppp-RNA Activates Antiviral Signal through Redistribution of IPS-1 Mediated by MFN1

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Interferon, Mx, and viral countermeasures

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Regulation of Virus-triggered Signaling by OTUB1- and OTUB2-mediated Deubiquitination of TRAF3 and TRAF6

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The Feedback Phase of Type I Interferon Induction in Dendritic Cells Requires Interferon Regulatory Factor 8

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Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity

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Structural basis for the prion-like MAVS filaments in antiviral innate immunity

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Double-Stranded RNA Induces an Antiviral Defense Status in Epidermal Keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-Mediated Differential Signaling

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DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication

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Herpes Simplex Virus 1 Tegument Protein US11 Downmodulates the RLR Signaling Pathway via Direct Interaction with RIG-I and MDA-5

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The E3 Ubiquitin Ligase RNF5 Targets Virus-Induced Signaling Adaptor for Ubiquitination and Degradation

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TRIM21 Is Essential to Sustain IFN Regulatory Factor 3 Activation during Antiviral Response

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Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus

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Activation of host pattern recognition receptors by viruses

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Hepatitis C Virus Non-structural Protein 3 (HCV NS3): A Multifunctional Antiviral Target

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USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase

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Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense

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Virus Infection Triggers SUMOylation of IRF3 and IRF7, Leading to the Negative Regulation of Type I Interferon Gene Expression

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The E3 Ubiquitin Ligase Triad3A Negatively Regulates the RIG-I/MAVS Signaling Pathway by Targeting TRAF3 for Degradation

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Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7

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dsRNA-Dependent Protein Kinase PKR and its Role in Stress, Signaling and HCV Infection

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ISG15 and immune diseases

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Tom70 mediates activation of interferon regulatory factor 3 on mitochondria

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LRRC25 inhibits type I IFN signaling by targeting ISG15‐associated RIG‐I for autophagic degradation

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Unanchored K48-Linked Polyubiquitin Synthesized by the E3-Ubiquitin Ligase TRIM6 Stimulates the Interferon-IKKε Kinase-Mediated Antiviral Response

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TAX1BP1 and A20 Inhibit Antiviral Signaling by Targeting TBK1-IKKi Kinases

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The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA

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The chemotherapeutic agent DMXAA potently and specifically activates the TBK1–IRF-3 signaling axis

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IFN-Induced TPR Protein IFIT3 Potentiates Antiviral Signaling by Bridging MAVS and TBK1

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p53 engages the cGAS/STING cytosolic DNA sensing pathway for tumor suppression

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Hepatitis C Virus Nonstructural Protein 5A Modulates the Toll-Like Receptor-MyD88-Dependent Signaling Pathway in Macrophage Cell Lines

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Principles of intracellular viral recognition

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Intracellular Pathogen Detection by RIG-I-Like Receptors

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Regulation of Signal Transduction by Enzymatically Inactive Antiviral RNA Helicase Proteins MDA5, RIG-I, and LGP2

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TRIM21 Promotes Innate Immune Response to RNA Viral Infection through Lys27-Linked Polyubiquitination of MAVS

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Alarmins, inflammasomes and immunity

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USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA

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Polycation-based nanoparticle delivery of RNAi therapeutics: Adverse effects and solutions

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The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling

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RNA:DNA hybrids are a novel molecular pattern sensed by TLR9

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MDA5 and MAVS Mediate Type I Interferon Responses to Coxsackie B Virus

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Human Papillomavirus Deregulates the Response of a Cellular Network Comprising of Chemotactic and Proinflammatory Genes

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Regulation of lupus-related autoantibody production and clinical disease by Toll-like receptors

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Receptor (SLAM [CD150]) Recognition and the V Protein Sustain Swift Lymphocyte-Based Invasion of Mucosal Tissue and Lymphatic Organs by a Morbillivirus

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The fight between the teleost fish immune response and aquatic viruses

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Inhibition of RIG-I-Mediated Signaling by Kaposi's Sarcoma-Associated Herpesvirus-Encoded Deubiquitinase ORF64

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MAVS Dimer Is a Crucial Signaling Component of Innate Immunity and the Target of Hepatitis C Virus NS3/4A Protease

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Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus

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Mitochondria: the indispensable players in innate immunity and guardians of the inflammatory response

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Foot-and-Mouth Disease Virus 3C Protease Cleaves NEMO To Impair Innate Immune Signaling

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Z Proteins of New World Arenaviruses Bind RIG-I and Interfere with Type I Interferon Induction

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