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Visualization of omics data for systems biology

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Gehlenborg, Nils, O'Donoghue, Seán I, Baliga, Nitin S, Goesmann, Alexander, Hibbs, Matthew A, Kitano, Hiroaki, Kohlbacher, Oliver, Neuweger, Heiko, Schneider, Reinhard, Tenenbaum, Dan, Gavin, Anne-Claude·2010·Nature Methods
DOI 10.1038/nmeth.1436
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Abstract

High-throughput studies of biological systems are rapidly accumulating a wealth of 'omics'-scale data. Visualization is a key aspect of both the analysis and understanding of these data, and users now have many visualization methods and tools to choose from. The challenge is to create clear, meaningful and integrated visualizations that give biological insight, without being overwhelmed by the intrinsic complexity of the data. In this review, we discuss how visualization tools are being used to help interpret protein interaction, gene expression and metabolic profile data, and we highlight emerging new directions.

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Metadata

Authors
Gehlenborg, N., O'Donoghue, S. I., Baliga, N. S., Goesmann, A., Hibbs, M. A., Kitano, H., Kohlbacher, O., Neuweger, H., Schneider, R., Tenenbaum, D., & Gavin, A.-C.
Venue
Nature Methods
Publisher
Springer Science and Business Media LLC
Published
2010-03
Volume
7
Issue
S3
Pages
S56-S68
ISSN
  • 1548-7091 (ISSN-L)
  • 1548-7105
DOI
10.1038/nmeth.1436
OpenAlex
W2023098599
Cited by
620
References
17
FWCI
26.94
Type
journal article
Language
en
Open access
green
Licence
www.springer.com/tdm (tdm)

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Gehlenborg, N., O'Donoghue, S. I., Baliga, N. S., Goesmann, A., Hibbs, M. A., Kitano, H., Kohlbacher, O., Neuweger, H., Schneider, R., Tenenbaum, D., & Gavin, A.-C. (2010). Visualization of omics data for systems biology. Nature Methods. https://doi.org/10.1038/nmeth.1436

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