The oligodendrocyte-specific G protein–coupled receptor GPR17 is a cell-intrinsic timer of myelination

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

Bernstein, B. E., Mikkelsen, T. S., Xie, X., Kamal, M., Huebert, D. J., Cuff, J., Fry, B., Meissner, A., Wernig, M., Plath, K., et al. (2006) · Cell · doi:10.1016/j.cell.2006.02.041 · Cited by 5,361 · see citing works

Axonal transection in the lesions of multiple sclerosis

Trapp, B. D., Peterson, J., Ransohoff, R. M., Rudick, R., Mörk, S., & Bö, L. (1998) · New England Journal of Medicine · doi:10.1056/nejm199801293380502 · Cited by 4,029 · see citing works

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4178-07.2008 · Cited by 3,129 · see citing works

Microglia-specific localisation of a novel calcium binding protein, Iba1

Ito, D., Imai, Y., Ohsawa, K., Nakajima, K., Fukuuchi, Y., & Kohsaka, S. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(98)00040-0 · Cited by 1,476 · see citing works

Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.

Lu, Q. R., Sun, T., Zhu, Z.-M., Ma, N., García, M., Stiles, C., & Rowitch, D. (2002) · Cell · doi:10.1016/s0092-8674(02)00678-5 · Cited by 1,064 · see citing works

The bHLH Transcription Factors OLIG2 and OLIG1 Couple Neuronal and Glial Subtype Specification

Zhou, Q., & Anderson, D. J. (2002) · Cell · doi:10.1016/s0092-8674(02)00677-3 · Cited by 1,059 · see citing works

Premyelinating Oligodendrocytes in Chronic Lesions of Multiple Sclerosis

Chang, A., Tourtellotte, W. W., Rudick, R., & Trapp, B. D. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa010994 · Cited by 991 · see citing works

Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system.

Lu, Q. R., Yuk, D.-I., Alberta, J., Zhu, Z.-M., Pawlitzky, I., Chan, J., McMahon, A., Stiles, C., & Rowitch, D. H. (2000) · Neuron · doi:10.1016/s0896-6273(00)80897-1 · Cited by 883 · see citing works

The oligodendrocyte and its many cellular processes

Pfeiffer, S. E., Warrington, A. E., & Bansal, R. (1993) · Trends in Cell Biology · doi:10.1016/0962-8924(93)90213-k · Cited by 852 · see citing works

Why does remyelination fail in multiple sclerosis?

Franklin, R. J. M. (2002) · Nature reviews. Neuroscience · doi:10.1038/nrn917 · Cited by 837 · see citing works

NG2-Positive Oligodendrocyte Progenitor Cells in Adult Human Brain and Multiple Sclerosis Lesions

Chang, A., Nishiyama, A., Peterson, J. W., Prineas, J. W., & Trapp, B. D. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-17-06404.2000 · Cited by 711 · see citing works

Notch Receptor Activation Inhibits Oligodendrocyte Differentiation

Wang, S., Sdrulla, A. D., diSibio, G., Bush, G., Nofziger, D., Hicks, C. D., Weinmaster, G., & Barres, B. A. (1998) · Neuron · doi:10.1016/s0896-6273(00)80515-2 · Cited by 706 · see citing works

A mitogen gradient of dorsal midline Wnts organizes growth in the CNS

Megason, S. G., & McMahon, A. P. (2002) · Development · doi:10.1242/dev.129.9.2087 · Cited by 681 · see citing works

Basic helix-loop-helix factors in cortical development.

Ross, S. E., Greenberg, M., & Stiles, C. (2003) · Neuron · doi:10.1016/s0896-6273(03)00365-9 · Cited by 637 · see citing works

LINGO-1 negatively regulates myelination by oligodendrocytes

Mi, S., Miller, R. H., Lee, X., Scott, M. L., Shulag-Morskaya, S., Shao, Z., Chang, J., Thill, G., Levesque, M., Zhang, M., et al. (2005) · Nature Neuroscience · doi:10.1038/nn1460 · Cited by 628 · see citing works

A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development

Barrès, A., Lazar, M. A., & RAFF, M. C. (1994) · Development · doi:10.1242/dev.120.5.1097 · Cited by 593 · see citing works

Multiple sclerosis: Re-expression of a developmental pathway that restricts oligodendrocyte maturation

John, G. R., Shankar, S. L., Shafit‐Zagardo, B., Massimi, A. B., Lee, S. C., Raine, C. S., & Brosnan, C. F. (2002) · Nature Medicine · doi:10.1038/nm781 · Cited by 478 · see citing works

Axonal regulation of myelination by neuregulin 1

Nave, K., & Salzer, J. L. (2006) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2006.08.008 · Cited by 452 · see citing works

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl‐leukotrienes receptor

Ciana, P., Fumagalli, M., Trincavelli, M. L., Verderio, C., Rosa, P., Lecca, D., Ferrario, S., Parravicini, C., Capra, V., Gelosa, P., et al. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601341 · Cited by 438 · see citing works

bHLH Transcription Factor Olig1 Is Required to Repair Demyelinated Lesions in the CNS

Arnett, H. A., Fancy, S. P. J., Alberta, J. A., Zhao, C., Plant, S. R., Kaing, S., Raine, C. S., Rowitch, D. H., Franklin, R. J. M., & Stiles, C. D. (2004) · Science · doi:10.1126/science.1103709 · Cited by 416 · see citing works

Isolation and culture of rat and mouse oligodendrocyte precursor cells

Chen, Y., Balasubramaniyan, V., Peng, J., Hurlock, E. C., Tallquist, M. D., Li, J., & Lu, Q. R. (2007) · Nature Protocols · doi:10.1038/nprot.2007.149 · Cited by 409 · see citing works

F3/Contactin Acts as a Functional Ligand for Notch during Oligodendrocyte Maturation

Hu, Q., Ang, B.-T., Karsak, M., Hu, W.-P., Cui, X., Duka, T., Takeda, Y., Chia, W., Sankar, N., Ng, Y., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00810-9 · Cited by 367 · see citing works

Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation

Samanta, J., & Kessler, J. A. (2004) · Development · doi:10.1242/dev.01273 · Cited by 361 · see citing works

IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes

Hsieh, J., Aimone, J. B., Kaspar, B. K., Kuwabara, T., Nakashima, K., & Gage, F. H. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200308101 · Cited by 334 · see citing works

Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro.

Gabay, L., Lowell, S., Lee, R.-B. L., & Anderson, D. J. (2003) · Neuron · doi:10.1016/s0896-6273(03)00637-8 · Cited by 326 · see citing works

Accumulation of the cyclin‐dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation

Durand, B., Gao, F., & RAFF, M. C. (1997) · The EMBO Journal · doi:10.1093/emboj/16.2.306 · Cited by 324 · see citing works

Activation and Proliferation of Endogenous Oligodendrocyte Precursor Cells during Ethidium Bromide-Induced Demyelination

Levine, J. M., & Reynolds, R. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7224 · Cited by 282 · see citing works

A Role for the Helix-Loop-Helix Protein Id2 in the Control of Oligodendrocyte Development

Wang, S., Sdrulla, A. D., Johnson, J. E. B., Yokota, Y., & Barres, B. A. (2001) · Neuron · doi:10.1016/s0896-6273(01)00237-9 · Cited by 261 · see citing works

Myelinogenesis and Axonal Recognition by Oligodendrocytes in Brain Are Uncoupled in Olig1-Null Mice

Xin, M., Yue, T., Ma, Z.-Y., Wu, F.-F., Gow, A., & Lu, Q. R. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3034-04.2005 · Cited by 253 · see citing works

Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1Preprint

Casaccia‐Bonnefil, P., Tikoo, R., Kiyokawa, H., Friedrich, V. L., Chao, M. V., & Koff, A. (1997) · Genes & Development · doi:10.1101/gad.11.18.2335 · Cited by 252 · see citing works

A cell-intrinsic timer that operates during oligodendrocyte development

Durand, B., & RAFF, M. C. (2000) · BioEssays · doi:10.1002/(sici)1521-1878(200001)22:1 · Cited by 243 · see citing works

The Recently Identified P2Y-Like Receptor GPR17 Is a Sensor of Brain Damage and a New Target for Brain Repair

Lecca, D., Trincavelli, M. L., Gelosa, P., Sironi, L., Ciana, P., Fumagalli, M., Villa, G. C. F., Verderio, C., Grumelli, C., Guerrini, U., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003579 · Cited by 227 · see citing works

A crucial role for Olig2 in white matter astrocyte development

Cai, J., Chen, Y., Cai, W.-H., Hurlock, E. C., Wu, H., Kernie, S. G., Parada, L. F., & Lu, Q. R. (2007) · Development · doi:10.1242/dev.02847 · Cited by 203 · see citing works

The Id4 HLH protein and the timing of oligodendrocyte differentiation

Kondo, T., & Raff, M. (2000) · The EMBO Journal · doi:10.1093/emboj/19.9.1998 · Cited by 203 · see citing works

Olig1 and Sox10 Interact Synergistically to Drive Myelin Basic Protein Transcription in Oligodendrocytes

Li, H., Lu, Y., Smith, H., & Richardson, W. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4456-07.2007 · Cited by 180 · see citing works

Axonal Neuregulin Signals Cells of the Oligodendrocyte Lineage through Activation of HER4 and Schwann Cells through HER2 and HER3

Vartanian, T. K., Goodearl, A. D. J., Viehöver, A., & Fischbach, G. D. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.137.1.211 · Cited by 173 · see citing works

Myelin basic protein gene contains separate enhancers for oligodendrocyte and Schwann cell expression

Gow, A., Friedrich, V. L., & Lazzarini, R. A. (1992) · The Journal of Cell Biology · doi:10.1083/jcb.119.3.605 · Cited by 147 · see citing works

Combinatorial Profiles of Oligodendrocyte-Selective Classes of Transcriptional Regulators Differentially Modulate Myelin Basic Protein Gene Expression

Gokhan, S., Marin-Husstege, M., Yung, S.-Y., Fontanez, D. E., Casaccia-Bonnefil, P., & Mehler, M. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1850-05.2005 · Cited by 123 · see citing works

An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation

Wang, S., Dulin, J., Wu, H., Hurlock, E., Lee, S.-E., Jansson, K. P., & Lu, Q. R. (2006) · Development · doi:10.1242/dev.02522 · Cited by 122 · see citing works

Loss of p27Kip1 function results in increased proliferative capacity of oligodendrocyte progenitors but unaltered timing of differentiation

Casaccia‐Bonnefil, P., Hardy, R. J., Teng, K. K., Levine, J. M., Koff, A., & Chao, M. V. (1999) · Development · doi:10.1242/dev.126.18.4027 · Cited by 120 · see citing works

Neurological mouse mutants and the genes of myelin

Nave, K. (1994) · Journal of Neuroscience Research · doi:10.1002/jnr.490380602 · Cited by 98 · see citing works

Multiple roles of Id4 in developmental myelination: predicted outcomes and unexpected findings

Marin‐Husstege, M., He, Y., Li, J., Kondo, T., Sablitzky, F., & Casaccia‐Bonnefil, P. (2006) · Glia · doi:10.1002/glia.20385 · Cited by 91 · see citing works

A Critical Role for Dorsal Progenitors in Cortical Myelination

Yue, T., Xian, K., Hurlock, E., Xin, M., Kernie, S., Parada, L., & Lu, Q. R. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4717-05.2006 · Cited by 91 · see citing works

Four-kilobase sequence of the mouse CNP gene directs spatial and temporal expression of lacZ in transgenic mice

Gravel, M., Polo, A. D., Valera, P. B., & Braun, P. E. (1998) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19980815)53:4 · Cited by 82 · see citing works

A Crucial Role for p57Kip2 in the Intracellular Timer that Controls Oligodendrocyte Differentiation

Dugas, J. C., Ibrahim, A., & Barres, B. A. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0628-07.2007 · Cited by 77 · see citing works

Posttranscriptional Regulation of p18 and p27 Cdk Inhibitor Proteins and the Timing of Oligodendrocyte Differentiation

Tokumoto, Y. M., Apperly, J. A., Gao, F., & RAFF, M. C. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0626 · Cited by 72 · see citing works

Tissue-Specific Up-Regulation of B7-1 Expression and Function During the Course of Murine Relapsing Experimental Autoimmune Encephalomyelitis

Karandikar, N. J., Vanderlugt, C. L., Eagar, T. N., Tan, L., Bluestone, J. A., & Miller, S. D. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.1.192 · Cited by 68 · see citing works

Leukodystrophies: recent developments in genetics, molecular biology, pathogenesis and treatment*

Berger, J., Moser, H. W., & Forss‐Petter, S. (2001) · Current Opinion in Neurology · doi:10.1097/00019052-200106000-00007 · Cited by 64 · see citing works

GPR17: Molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors

Parravicini, C., Ranghino, G., Abbracchio, M. P., & Fantucci, P. (2008) · BMC Bioinformatics · doi:10.1186/1471-2105-9-263 · Cited by 61 · see citing works

Molecular Biology of Myelination

Campagnoni, A. T. (2004) · Neuroglia · doi:10.1093/acprof:oso/9780195152227.003.0019 · Cited by 10 · see citing works

Receptors for Purines and Pyrimidines

Burnstock, G., & Verkhratsky, A. (2012) · Springer eBooks · doi:10.1007/978-3-642-28863-0_5 · Cited by 3,973 · see citing works

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system

Marques, S., Zeisel, A., Codeluppi, S., van Bruggen, D., Mendanha Falcão, A., Xiao, L., Li, H., Häring, M., Hochgerner, H., Romanov, R. A., et al. (2016) · Science · doi:10.1126/science.aaf6463 · Cited by 1,246 · see citing works

Myelination of the Nervous System: Mechanisms and Functions

Nave, K., & Werner, H. B. (2014) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100913-013101 · Cited by 1,000 · see citing works

Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease

Haeggström, J. Z., & Funk, C. D. (2011) · Chemical Reviews · doi:10.1021/cr200246d · Cited by 875 · see citing works

Regulation of oligodendrocyte differentiation and myelination

Emery, B. (2010) · Science · doi:10.1126/science.1190927 · Cited by 653 · see citing works

Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity

Chen, R., Wu, X., Jiang, L., & Zhang, Y. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.03.004 · Cited by 592 · see citing works

White matter and cognition: making the connection

Filley, C. M., & Fields, R. D. (2016) · Journal of Neurophysiology · doi:10.1152/jn.00221.2016 · Cited by 445 · see citing works

Purinergic signalling: From normal behaviour to pathological brain function

Burnstock, G., Krügel, U., Abbracchio, M. P., & Illés, P. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.08.006 · Cited by 394 · see citing works

Myelin Regeneration: A Recapitulation of Development?

Fancy, S. P. J., Chan, J. R., Baranzini, S. E., Franklin, R. J. M., & Rowitch, D. H. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113629 · Cited by 321 · see citing works

Transcriptional and Epigenetic Regulation of Oligodendrocyte Development and Myelination in the Central Nervous SystemPreprint

Emery, B., & Lu, Q. R. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020461 · Cited by 293 · see citing works

Origin and dynamics of oligodendrocytes in the developing brain: Implications for perinatal white matter injury

van Tilborg, E., de Theije, C. G. M., van Hal, M., Wagenaar, N., de Vries, L. S., Benders, M. J. N. L., Rowitch, D. H., & Nijboer, C. H. A. (2017) · Glia · doi:10.1002/glia.23256 · Cited by 292 · see citing works

Signals to promote myelin formation and repair

Taveggia, C., Feltri, M. L., & Wrabetz, L. G. (2010) · Nature Reviews Neurology · doi:10.1038/nrneurol.2010.37 · Cited by 281 · see citing works

NG 2‐glia and their functions in the central nervous system

Dimou, L., & Gallo, V. (2015) · Glia · doi:10.1002/glia.22859 · Cited by 258 · see citing works

Mechanisms regulating the development of oligodendrocytes and central nervous system myelin.

Mitew, S., Hay, C., Peckham, H., Xiao, J., Koenning, M., & Emery, B. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2013.11.029 · Cited by 259 · see citing works

Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation

Marisca, R., Hoche, T., Agirre, E., Hoodless, L. J., Barkey, W., Auer, F., Castelo‐Branco, G., & Czopka, T. (2020) · Nature Neuroscience · doi:10.1038/s41593-019-0581-2 · Cited by 246 · see citing works

Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination

Chong, S. Y. C., Rosenberg, S. S., Fancy, S. P. J., Zhao, C., Shen, Y.-A. A., Hahn, A. T., McGee, A. W., Xu, X., Zheng, B., Zhang, L. I., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1113540109 · Cited by 232 · see citing works

How to make an oligodendrocyte

Goldman, S. A., & Kuypers, N. J. (2015) · Development · doi:10.1242/dev.126409 · Cited by 226 · see citing works

YAP/TAZ-CDC42 signaling regulates vascular tip cell migration

Sakabe, M., Fan, J., Odaka, Y., Liu, N., Hassan, A., Duan, X., Stump, P., Byerly, L., Donaldson, M., Hao, J., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1704030114 · Cited by 204 · see citing works

FoxO1 Target Gpr17 Activates AgRP Neurons to Regulate Food Intake

Ren, H., Orozco, I. J., Su, Y., Suyama, S., Juárez, R. G., Horváth, T. L., Wardlaw, S. L., Plum, L., Arancio, O., & Accili, D. (2012) · Cell · doi:10.1016/j.cell.2012.04.032 · Cited by 201 · see citing works

An introduction to the roles of purinergic signalling in neurodegeneration, neuroprotection and neuroregeneration

Burnstock, G. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.05.031 · Cited by 200 · see citing works

Overcoming remyelination failure in multiple sclerosis and other myelin disorders.

Fancy, S., Kotter, M., Harrington, E. P., Huang, J. K., Zhao, C., Rowitch, D., & Franklin, R. (2010) · Experimental Neurology · doi:10.1016/j.expneurol.2009.12.020 · Cited by 201 · see citing works

Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug

Marschallinger, J., Schäffner, I., Klein, B., Gelfert, R., Rivera, F. J., Illes, S., Grassner, L., Janssen, M., Rotheneichner, P., Schmuckermair, C., et al. (2015) · Nature Communications · doi:10.1038/ncomms9466 · Cited by 193 · see citing works

Adenosine and ATP Receptors in the Brain

Burnstock, G., Fredholm, B. B., & Verkhratsky, A. (2011) · Current Topics in Medicinal Chemistry · doi:10.2174/156802611795347627 · Cited by 188 · see citing works

Phenotypic Changes, Signaling Pathway, and Functional Correlates of GPR17-expressing Neural Precursor Cells during Oligodendrocyte Differentiation

Fumagalli, M., Daniele, S., Lecca, D., Lee, P. R., Parravicini, C., Fields, R. D., Rosa, P., Antonucci, F., Verderio, C., Trincavelli, M. L., et al. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.162867 · Cited by 188 · see citing works

HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination

Chen, Y., Wang, H., Yoon, S. O., Xu, X., Hottiger, M. O., Svaren, J. P., Nave, K. A., Kim, H. A., Olson, E. N., & Lu, Q. R. (2011) · Nature Neuroscience · doi:10.1038/nn.2780 · Cited by 175 · see citing works

Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2

Meijer, D., Kane, M., Mehta, S., Liu, H.-Y., Harrington, E. P., Taylor, C. M., Stiles, C., & Rowitch, D. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3386 · Cited by 166 · see citing works

Dual-mode Modulation of Smad Signaling by Smad-interacting Protein Sip1 is Required for Myelination in the CNS

Weng, Q.-J., Chen, Y., Wang, H.-B., Xu, X., Yang, B., He, Q., Shou, W., Chen, Y., Higashi, Y., van den Berghe, V., et al. (2012) · Neuron · doi:10.1016/j.neuron.2011.12.021 · Cited by 165 · see citing works

Dlx1&2-Dependent Expression of Zfhx1b (Sip1, Zeb2) Regulates the Fate Switch between Cortical and Striatal Interneurons

McKinsey, G. L., Lindtner, S., Trzcinski, B., Visel, A., Pennacchio, L. A., Huylebroeck, D., Higashi, Y., & Rubenstein, J. L. R. (2013) · Neuron · doi:10.1016/j.neuron.2012.11.035 · Cited by 153 · see citing works

Ascl1/Mash1 Promotes Brain Oligodendrogenesis during Myelination and Remyelination

Nakatani, H., Martin, E., Hassani, H., Clavairoly, A., Maire, C. L., Viadieu, A., Kerninon, C., Delmasure, A., Frah, M., Weber, M., et al. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0805-13.2013 · Cited by 158 · see citing works

International Union of Basic and Clinical Pharmacology. LXXXIV: Leukotriene Receptor Nomenclature, Distribution, and Pathophysiological Functions

Bäck, M., Dahlén, S., Drazen, J. M., Evans, J. F., Serhan, C. N., Shimizu, T., Yokomizo, T., & Rovati, G. E. (2011) · Pharmacological Reviews · doi:10.1124/pr.110.004184 · Cited by 151 · see citing works

G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

Yang, H., Vainshtein, A., Maik-Rachline, G., & Peles, E. (2016) · Nature Communications · doi:10.1038/ncomms10884 · Cited by 150 · see citing works

The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα12/13 and RhoA

Ackerman, S. D., Garcia, C. M., Piao, X., Gutmann, D. H., & Monk, K. R. (2015) · Nature Communications · doi:10.1038/ncomms7122 · Cited by 149 · see citing works

Oligodendroglial Expression of TrkB Independently Regulates Myelination and Progenitor Cell Proliferation

Wong, A. W., Xiao, J., Kemper, D., Kilpatrick, T. J., & Murray, S. S. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3990-12.2013 · Cited by 147 · see citing works

Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells

Giera, S., Luo, R., Ying, Y., Ackerman, S. D., Jeong, S.-J., Stoveken, H. M., Folts, C. J., Welsh, C. A., Tall, G. G., Stevens, B., et al. (2018) · eLife · doi:10.7554/elife.33385 · Cited by 145 · see citing works

Decoding Signaling and Function of the Orphan G Protein–Coupled Receptor GPR17 with a Small-Molecule Agonist

Hennen, S., Wang, H., Peters, L., Merten, N., Simon, K., Spinrath, A., Blättermann, S., Akkari, R., Schrage, R., Schröder, R. J., et al. (2013) · Science Signaling · doi:10.1126/scisignal.2004350 · Cited by 143 · see citing works

Cell of all trades: oligodendrocyte precursor cells in synaptic, vascular, and immune functionPreprint

Akay, L. A., Effenberger, A. H., & Tsai, L. (2021) · Genes & Development · doi:10.1101/gad.344218.120 · Cited by 142 · see citing works

Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia

Wang, J., He, X., Meng, H., Li, Y., Dmitriev, P., Tian, F., Page, J. C., Lu, Q. R., & He, Z. (2020) · Neuron · doi:10.1016/j.neuron.2020.09.016 · Cited by 139 · see citing works

Pluripotent Stem Cell-Derived Cerebral Organoids Reveal Human Oligodendrogenesis with Dorsal and Ventral Origins

Kim, H., Xu, R., Padmashri, R., Dunaevsky, A., Liu, Y., Dreyfus, C. F., & Jiang, P. (2019) · Stem Cell Reports · doi:10.1016/j.stemcr.2019.04.011 · Cited by 135 · see citing works

Neuronal ambient RNA contamination causes misinterpreted and masked cell types in brain single-nuclei datasets

Caglayan, E., Liu, Y., & Konopka, G. (2022) · Neuron · doi:10.1016/j.neuron.2022.09.010 · Cited by 123 · see citing works

The complex world of oligodendroglial differentiation inhibitors

Kremer, D., Aktaş, O., Hartung, H., & Küry, P. (2011) · Annals of Neurology · doi:10.1002/ana.22415 · Cited by 129 · see citing works

Olig1 Function Is Required for Oligodendrocyte Differentiation in the Mouse Brain

Dai, J., Bercury, K., Ahrendsen, J. T., & Macklin, W. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.4962-14.2015 · Cited by 108 · see citing works

Lineage, fate, and fate potential of NG2-glia

Nishiyama, A., Boshans, L. L., Gonçalves, C. M., Wegrzyn, J., & Patel, K. D. (2015) · Brain Research · doi:10.1016/j.brainres.2015.08.013 · Cited by 120 · see citing works

The GPR17 receptor in NG2 expressing cells: Focus on in vivo cell maturation and participation in acute trauma and chronic damage

Boda, E., Viganò, F., Rosa, P., Fumagalli, M., Labat-gest, V., Tempia, F., Abbracchio, M. P., Dimou, L., & Buffo, A. (2011) · Glia · doi:10.1002/glia.21237 · Cited by 117 · see citing works

Pathophysiological Role of Purines and Pyrimidines in Neurodevelopment: Unveiling New Pharmacological Approaches to Congenital Brain Diseases

Fumagalli, M., Lecca, D., Abbracchio, M. P., & Ceruti, S. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00941 · Cited by 116 · see citing works

Eicosanoids and Their Drugs in Cardiovascular Diseases: Focus on Atherosclerosis and Stroke

Capra, V., Bäck, M., Barbieri, S. S., Camera, M., Tremoli, E., & Rovati, G. E. (2012) · Medicinal Research Reviews · doi:10.1002/med.21251 · Cited by 115 · see citing works

The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke

Bonfanti, E., Gelosa, P., Fumagalli, M., Dimou, L., Viganò, F., Tremoli, E., Cimino, M., Sironi, L., & Abbracchio, M. P. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.256 · Cited by 106 · see citing works

Myelin inhibits oligodendroglial maturation and regulates oligodendrocytic transcription factor expression

Plemel, J. R., Manesh, S. B., Sparling, J. S., & Tetzlaff, W. (2013) · Glia · doi:10.1002/glia.22535 · Cited by 107 · see citing works

Integrated multi-omics analysis of oligodendroglial tumours identifies three subgroups of 1p/19q co-deleted gliomas

Kamoun, A., Idbaïh, A., Dehais, C., Elarouci, N., Carpentier, C., Letouzé, É., Colin, C., Mokhtari, K., Jouvet, A., Uro‐Coste, E., et al. (2016) · Nature Communications · doi:10.1038/ncomms11263 · Cited by 104 · see citing works

The G protein-coupled receptors deorphanization landscape

Laschet, C., Dupuis, N., & Hanson, J. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.02.016 · Cited by 101 · see citing works

Diversity in the oligodendrocyte lineage: Plasticity or heterogeneity?

Foerster, S., Hill, M. F. E., & Franklin, R. J. M. (2019) · Glia · doi:10.1002/glia.23607 · Cited by 103 · see citing works

Axonal selection and myelin sheath generation in the central nervous system

Simons, M., & Lyons, D. A. (2013) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2013.04.007 · Cited by 102 · see citing works

The white matter is a pro-differentiative niche for glioblastoma

Brooks, L. J., Clements, M., Burden, J. J., Kocher, D., Richards, L., Devesa, S. C., Zakka, L., Woodberry, M., Ellis, M. J., Jaunmuktane, Z., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22225-w · Cited by 101 · see citing works

The CNS Myelin Proteome: Deep Profile and Persistence After Post-mortem Delay

Jahn, O., Siems, S. B., Kusch, K., Hesse, D., Jung, R. B., Liepold, T., Uecker, M., Sun, T., & Werner, H. B. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00239 · Cited by 99 · see citing works

Molecular diversity and evolution of neuron types in the amniote brain

Hain, D., Gallego‐Flores, T., Klinkmann, M., Macias, A., Ciirdaeva, E., Arends, A., Thum, C., Tushev, G., Kretschmer, F., Tosches, M. A., et al. (2022) · Science · doi:10.1126/science.abp8202 · Cited by 100 · see citing works

Premyelinating Oligodendrocytes: Mechanisms Underlying Cell Survival and Integration

Hughes, E. G., & Stockton, M. E. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.714169 · Cited by 98 · see citing works

Transcriptional and post-transcriptional control of CNS myelination

Emery, B. (2010) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.05.005 · Cited by 92 · see citing works

The logistics of myelin biogenesis in the central nervous system

Snaidero, N., & Simons, M. (2017) · Glia · doi:10.1002/glia.23116 · Cited by 88 · see citing works

GPR17 expressing NG2‐Glia: Oligodendrocyte progenitors serving as a reserve pool after injury

Viganò, F., Schneider, S. E., Cimino, M., Bonfanti, E., Gelosa, P., Sironi, L., Abbracchio, M. P., & Dimou, L. (2015) · Glia · doi:10.1002/glia.22929 · Cited by 91 · see citing works

Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination

Ou, Z., Sun, Y., Li, L., You, N., Liu, X., Li, H., Ma, Y., Cao, L., Han, Y., Liu, M., et al. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.0898-16.2016 · Cited by 91 · see citing works

Osteocalcin attenuates oligodendrocyte differentiation and myelination via GPR37 signaling in the mouse brain

Qian, Z., Li, H., Yang, H., Yang, Q., Lu, Z., Wang, L., Chen, Y., & Li, X. (2021) · Science Advances · doi:10.1126/sciadv.abi5811 · Cited by 91 · see citing works

Oligodendrocyte Dysfunction in Amyotrophic Lateral Sclerosis: Mechanisms and Therapeutic Perspectives

Raffaele, S., Boccazzi, M., & Fumagalli, M. (2021) · Cells · doi:10.3390/cells10030565 · Cited by 86 · see citing works

Coordinated control of oligodendrocyte development by extrinsic and intrinsic signaling cues

He, L., & Lu, Q. R. (2013) · Neuroscience Bulletin · doi:10.1007/s12264-013-1318-y · Cited by 82 · see citing works

The Orphan G Protein-coupled Receptor GPR17 Negatively Regulates Oligodendrocyte Differentiation via Gαi/o and Its Downstream Effector Molecules

Simon, K., Hennen, S., Merten, N., Blättermann, S., Gillard, M. R., Kostenis, E., & Gomeza, J. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.683953 · Cited by 83 · see citing works

CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles of purinergic signaling and the P2Y-like receptor GPR17

Fumagalli, M., Lecca, D., & Abbracchio, M. P. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.10.005 · Cited by 81 · see citing works

Extracellular cues influencing oligodendrocyte differentiation and (re)myelination

Wheeler, N. A., & Fuss, B. (2016) · Experimental Neurology · doi:10.1016/j.expneurol.2016.03.019 · Cited by 78 · see citing works

An overall view of the most common experimental models for multiple sclerosis

Dedoni, S., Scherma, M., Camoglio, C., Siddi, C., Dazzi, L., Puliga, R., Frau, J., Cocco, E., & Fadda, P. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106230 · Cited by 79 · see citing works

Diversity of oligodendrocytes and their progenitors

Dimou, L., & Simons, M. (2017) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.09.015 · Cited by 77 · see citing works

Diversity and Function of Glial Cell Types in Multiple Sclerosis

Schirmer, L., Schafer, D. P., Bartels, T., Rowitch, D. H., & Calabresi, P. A. (2021) · Trends in Immunology · doi:10.1016/j.it.2021.01.005 · Cited by 75 · see citing works

MiR-125a-3p timely inhibits oligodendroglial maturation and is pathologically up-regulated in human multiple sclerosis

Lecca, D., Marangon, D., Coppolino, G., Méndez, A. M., Finardi, A., Costa, G. D., Martinelli, V., Furlan, R., & Abbracchio, M. P. (2016) · Scientific Reports · doi:10.1038/srep34503 · Cited by 76 · see citing works

Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration

Liu, X., Xin, D. E., Zhong, X., Zhao, C., Li, Z., Zhang, L., Dourson, A. J., Lee, L., Mishra, S. V., Bayat, A. E., et al. (2024) · Cell · doi:10.1016/j.cell.2024.04.005 · Cited by 76 · see citing works

Anti-Muscarinic Adjunct Therapy Accelerates Functional Human Oligodendrocyte Repair

Abiraman, K., Pol, S. U., O’Bara, M. A., Chen, G., Khaku, Z. M., Wang, J., Thorn, D. A., Vedia, B. H., Ekwegbalu, E. C., Li, J., et al. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.3510-14.2015 · Cited by 75 · see citing works

The new P2Y-like receptor G protein-coupled receptor 17 mediates acute neuronal injury and late microgliosis after focal cerebral ischemia in rats

Zhao, B., Zhao, C.-Z., Zhang, X., Huang, X., Shi, W., Fang, S. H., Lu, Y., Zhang, W. P., Xia, Q., & Wei, E. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.11.066 · Cited by 74 · see citing works

The heterogeneous nature of NG2-glia

Viganò, F., & Dimou, L. (2015) · Brain Research · doi:10.1016/j.brainres.2015.09.012 · Cited by 72 · see citing works

Vitamin C promotes oligodendrocytes generation and remyelination

Guo, Y., Suo, N., Cui, X. J., Yuan, Q., & Xie, X. (2018) · Glia · doi:10.1002/glia.23306 · Cited by 73 · see citing works

Expression of the new P2Y-like receptor GPR17 during oligodendrocyte precursor cell maturation regulates sensitivity to ATP-induced death

Ceruti, S., Viganò, F., Boda, E., Ferrario, S., Magni, G., Boccazzi, M., Rosa, P., Buffo, A., & Abbracchio, M. P. (2010) · Glia · doi:10.1002/glia.21107 · Cited by 70 · see citing works

Evidence for oligodendrocyte progenitor cell heterogeneity in the adult mouse brain

Beiter, R. M., Rivet-Noor, C. R., Merchak, A. R., Bai, R., Johanson, D. M., Slogar, E. R., Sol‐Church, K., Overall, C. C., & Gaultier, A. (2022) · Scientific Reports · doi:10.1038/s41598-022-17081-7 · Cited by 70 · see citing works

Candidate Pathways for Promoting Differentiation or Quiescence of Oligodendrocyte Progenitor-like Cells in Glioma

Dougherty, J. D., Fomchenko, E. I., Akuffo, A. A., Schmidt, E. F., Helmy, K. Y., Bazzoli, E., Brennan, C., Holland, E. C., & Milosevic, A. (2012) · Cancer Research · doi:10.1158/0008-5472.can-11-2632 · Cited by 67 · see citing works

mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development

Wood, T., Bercury, K., Cifelli, S. E., Mursch, L. E., Min, J., Dai, J., & Macklin, W. (2013) · ASN Neuro · doi:10.1042/an20120092 · Cited by 67 · see citing works

Is GPR17 a P2Y/Leukotriene Receptor? Examination of Uracil Nucleotides, Nucleotide Sugars, and Cysteinyl Leukotrienes as Agonists of GPR17

Qi, A. D., Harden, T. K., & Nicholas, R. A. (2013) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.113.207647 · Cited by 67 · see citing works

Proteomic identification of novel targets regulated by the mammalian target of rapamycin pathway during oligodendrocyte differentiation

Tyler, W. A., Jain, M. R., Cifelli, S. E., Li, Q., Ku, L., Feng, Y., Hong Li, A., & Wood, T. L. (2011) · Glia · doi:10.1002/glia.21221 · Cited by 67 · see citing works

Microglial cystatin F expression is a sensitive indicator for ongoing demyelination with concurrent remyelination

Ma, J.-M., Tanaka, K., Shimizu, T., Bernard, C., Kakita, A., Takahashi, H., Pfeiffer, S., & Ikenaka, K. (2011) · Journal of Neuroscience Research · doi:10.1002/jnr.22567 · Cited by 67 · see citing works

A mutation in the Tubb4a gene leads to microtubule accumulation with hypomyelination and demyelination

Duncan, I. D., Bugiani, M., Radcliff, A., Moran, J. J., Lopez-Anido, C., Duong, P. C., August, B. K., Wolf, N. I., van der Knaap, M. S., & Svaren, J. (2017) · Annals of Neurology · doi:10.1002/ana.24930 · Cited by 57 · see citing works

Oligodendrocyte death initiates synchronous remyelination to restore cortical myelin patterns in mice

Chapman, T. W., Olveda, G. E., Bame, X., Pereira, E., & Hill, R. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01271-1 · Cited by 65 · see citing works

A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism

Ou, Z., Ma, Y., Sun, Y., Zheng, G., Wang, S., Xing, R., Chen, X. '., Han, Y., Wang, J., Lu, Q. R., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.02.060 · Cited by 64 · see citing works

In silico identification of new ligands for GPR17: a promising therapeutic target for neurodegenerative diseases

Eberini, I., Daniele, S., Parravicini, C., Sensi, C., Trincavelli, M. L., Martini, C., & Abbracchio, M. P. (2011) · Journal of Computer-Aided Molecular Design · doi:10.1007/s10822-011-9455-8 · Cited by 63 · see citing works

Sox10 Cooperates with the Mediator Subunit 12 during Terminal Differentiation of Myelinating Glia

Vogl, M. R., Reiprich, S., Küspert, M., Kosian, T., Schrewe, H., Nave, K., & Wegner, M. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.5178-12.2013 · Cited by 62 · see citing works

UDP‐glucose enhances outward K+ currents necessary for cell differentiation and stimulates cell migration by activating the GPR17 receptor in oligodendrocyte precursors

Coppi, E., Maraula, G., Fumagalli, M., Failli, P., Cellai, L., Bonfanti, E., Mazzoni, L., Coppini, R., Abbracchio, M. P., Pedata, F., et al. (2013) · Glia · doi:10.1002/glia.22506 · Cited by 62 · see citing works

Neuro-psychopharmacological perspective of Orphan receptors of Rhodopsin (class A) family of G protein-coupled receptors

Khan, M. Z., & He, L. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4586-9 · Cited by 63 · see citing works

Oligodendrogliopathy in neurodegenerative diseases with abnormal protein aggregates: The forgotten partner

Ferrer, I. (2018) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.07.004 · Cited by 62 · see citing works

Transcriptional signatures of tau and amyloid neuropathology

Castanho, I., Murray, T. K., Hannon, E., Jeffries, A., Walker, E., Laing, E., Baulf, H., Harvey, J., Bradshaw, L., Randall, A., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.01.063 · Cited by 62 · see citing works

Cerebral cortex demyelination and oligodendrocyte precursor response to experimental autoimmune encephalomyelitis.

Girolamo, F., Ferrara, G., Strippoli, M., Rizzi, M., Errede, M., Trojano, M., Perris, R., Roncali, L., Svelto, M., Mennini, T., et al. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.05.021 · Cited by 60 · see citing works

Functional genomic analyses highlight a shift in <i>Gpr17</i> ‐regulated cellular processes in oligodendrocyte progenitor cells and underlying myelin dysregulation in the aged mouse cerebrum

Rivera, A. D., Pieropan, F., Chacon‐De‐La‐Rocha, I., Lecca, D., Abbracchio, M. P., Azim, K., & Butt, A. M. (2021) · Aging Cell · doi:10.1111/acel.13335 · Cited by 61 · see citing works

Differential local tissue permissiveness influences the final fate of GPR 17‐expressing oligodendrocyte precursors in two distinct models of demyelination

Coppolino, G., Marangon, D., Negri, C., Menichetti, G., Fumagalli, M., Gelosa, P., Dimou, L., Furlan, R., Lecca, D., & Abbracchio, M. P. (2018) · Glia · doi:10.1002/glia.23305 · Cited by 60 · see citing works

The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization

Fumagalli, M., Bonfanti, E., Daniele, S., Zappelli, E., Lecca, D., Martini, C., Trincavelli, M. L., & Abbracchio, M. P. (2015) · Glia · doi:10.1002/glia.22896 · Cited by 59 · see citing works

Cysteinyl Leukotrienes as Potential Pharmacological Targets for Cerebral Diseases

Gelosa, P., Colazzo, F., Tremoli, E., Sironi, L., & Castiglioni, L. (2017) · Mediators of Inflammation · doi:10.1155/2017/3454212 · Cited by 59 · see citing works

The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription

Katsel, P., Roussos, P., Fam, P. S., Khan, S., Tan, W., Hirose, T., Nakagawa, S., Pletnikov, M., & Haroutunian, V. (2019) · npj Schizophrenia · doi:10.1038/s41537-019-0071-2 · Cited by 74 · see citing works

Regulation and signaling of the GPR17 receptor in oligodendroglial cells

Lecca, D., Raffaele, S., Abbracchio, M. P., & Fumagalli, M. (2020) · Glia · doi:10.1002/glia.23807 · Cited by 58 · see citing works

Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain

Zhang, M., Wang, J., Zhang, K., Lu, G., Liu, Y., Ren, K., Wang, W., Xin, D. E., Xu, L., Mao, H., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-25353-5 · Cited by 58 · see citing works

Tapping into the glial reservoir: cells committed to remaining uncommitted

Chong, S. Y. C., & Chan, J. (2010) · Journal of Cell Biology · doi:10.1083/jcb.200905111 · Cited by 55 · see citing works

G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Differentiation in Response to Lysolecithin-Induced Demyelination

Lu, C., Dong, L., Zhou, H., Li, Q., Huang, G., Bai, S. J., & Liao, L. (2018) · Scientific Reports · doi:10.1038/s41598-018-22452-0 · Cited by 57 · see citing works

GPR17 modulates oligodendrocyte precursor cell maturation during development but has limited impact on myelin regeneration following demyelinating insultsPreprint

Puorro-Radzwill, K., Pang, P. T., Giera, S., Sheng, G., Farley, J. E., Garron, C., Danthi, S. J., Gans, J., Kumar, D., Agrawal, R. G., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.08.659146

The Orphan G Protein-coupled Receptor GPR17 Negatively Regulates Oligodendrocyte Differentiation via Gαi/o and Its Downstream Effector Molecules

Simon, K., Hennen, S., Merten, N., Blättermann, S., Gillard, M. R., Kostenis, E., & Gomeza, J. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.683953 · Cited by 83 · see citing works

ENDOCYTIC TRAFFIC OF THE G-PROTEIN COUPLED RECEPTOR 17, A DUALISTIC RECEPTOR IMPLICATED IN OLIGODENDROCYTE DIFFERENTIATION

Fratangeli, A. (2012) · Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) · doi:10.13130/fratangeli-alessandra_phd2012-02-03

G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Differentiation in Response to Lysolecithin-Induced Demyelination

Lu, C., Dong, L., Zhou, H., Li, Q., Huang, G., Bai, S. J., & Liao, L. (2018) · Scientific Reports · doi:10.1038/s41598-018-22452-0 · Cited by 57 · see citing works

Decoding Signaling and Function of the Orphan G Protein–Coupled Receptor GPR17 with a Small-Molecule Agonist

Hennen, S., Wang, H., Peters, L., Merten, N., Simon, K., Spinrath, A., Blättermann, S., Akkari, R., Schrage, R., Schröder, R. J., et al. (2013) · Science Signaling · doi:10.1126/scisignal.2004350 · Cited by 143 · see citing works