The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Neuronal reference frames for social decisions in primate frontal cortex
Open accessAbstract
Social decisions are crucial for the success of individuals and the groups that they comprise. Group members respond vicariously to benefits obtained by others, and impairments in this capacity contribute to neuropsychiatric disorders such as autism and sociopathy. We examined the manner in which neurons in three frontal cortical areas encoded the outcomes of social decisions as monkeys performed a reward-allocation task. Neurons in the orbitofrontal cortex (OFC) predominantly encoded rewards that were delivered to oneself. Neurons in the anterior cingulate gyrus (ACCg) encoded reward allocations to the other monkey, to oneself or to both. Neurons in the anterior cingulate sulcus (ACCs) signaled reward allocations to the other monkey or to no one. In this network of received (OFC) and foregone (ACCs) reward signaling, ACCg emerged as an important nexus for the computation of shared experience and social reward. Individual and species-specific variations in social decision-making might result from the relative activation and influence of these areas.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Prior investigations in rodents and primates, for example, have provided evidence for the presence of neurons that encode information about other individuals, demonstrating changes in activity when the animals observe another’s appetitive or aversive experiences 1–11.”
From Reduced sociability and social agency encoding in adult Shank3-mutant mice are restored through gene re-expression in real time (2021) · cites this paper as [2]
In the citing paper
“Previous investigations have provided insight into how discrete aspects of another animal’s experience, such as receipt of reward, may be encoded by cells 1–7,9.”
From Reduced sociability and social agency encoding in adult Shank3-mutant mice are restored through gene re-expression in real time (2021) · cites this paper as [2]
In the citing paper
“We have previously shown that videos promote interactive looking behaviors, e.g., eye contact, gaze-following, gaze-avoidance, and the reciprocation of facial expressions [12-17] as they better approximate natural interactions [18-20].”
From Neurons in the Monkey Amygdala Detect Eye Contact during Naturalistic Social Interactions (2014) · cites this paper as [18]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A neural substrate of prediction and reward
Schultz, W., Dayan, P., & Montague, P. R. (1997) · Science · doi:10.1126/science.275.5306.1593 · Cited by 9,388
Does the autistic child have a “theory of mind” ?
Baron-Cohen, S., Leslie, A. M., & Frith, U. (1985) · Cognition · doi:10.1016/0010-0277(85)90022-8 · Cited by 8,599
Empathy for Pain Involves the Affective but not Sensory Components of Pain
Singer, T., Seymour, B., O'Doherty, J., Kaube, H., Dolan, R. J., & Frith, C. D. (2004) · Science · doi:10.1126/science.1093535 · Cited by 3,929
Meeting of minds: the medial frontal cortex and social cognition
Amodio, D. M., & Frith, C. D. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1884 · Cited by 3,782
The Neural Basis of Decision Making
Gold, J. I., & Shadlen, M. N. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.113038 · Cited by 3,764
Frith, C., & Frith, U. (2005) · Current Biology · doi:10.1016/j.cub.2005.08.041 · Cited by 3,561
Fehr, E., & Fischbacher, U. (2003) · Nature · doi:10.1038/nature02043 · Cited by 3,475 · cited 2×
“Coefficients of variation were (1) np g © 2 01 3 N at ur e A m er ic a, In c.”
BackgroundMethodAnterior Cingulate Cortex, Error Detection, and the Online Monitoring of Performance
Carter, C. S., Braver, T. S., Barch, D. M., Botvinick, M. M., Noll, D., & Cohen, J. D. (1998) · Science · doi:10.1126/science.280.5364.747 · Cited by 3,273
A unifying view of the basis of social cognition
GALLESE, V, KEYSERS, C., & RIZZOLATTI, G. (2004) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2004.07.002 · Cited by 2,236
Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning
O'Doherty, J., Dayan, P., Schultz, J., Deichmann, R., Friston, K., & Dolan, R. J. (2004) · Science · doi:10.1126/science.1094285 · Cited by 2,088
The Neural Basis of Altruistic Punishment
de Quervain, D. J.-F., Fischbacher, U., Treyer, V., Schellhammer, M., Schnyder, U., Buck, A., & Fehr, E. (2004) · Science · doi:10.1126/science.1100735 · Cited by 1,768
Cognitive neuroscience of human social behaviour
Adolphs, R. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1056 · Cited by 1,657
Neurons in the orbitofrontal cortex encode economic value
Padoa-Schioppa, C., & Assad, J. A. (2006) · Nature · doi:10.1038/nature04676 · Cited by 1,598
A neural basis for social cooperation
Rilling, J. K., Gutman, D. A., Zeh, T. R., Pagnoni, G., Berns, G. S., & Kilts, C. D. (2002) · Neuron · doi:10.1016/s0896-6273(02)00755-9 · Cited by 1,451
Relative reward preference in primate orbitofrontal cortex
Tremblay, L., & Schultz, W. (1999) · Nature · doi:10.1038/19525 · Cited by 1,314
Limbic connections of the orbital and medial prefrontal cortex in macaque monkeys
Carmichael, S. T., & Price, J. L. (1995) · Journal of Comparative Neurology · doi:10.1002/cne.903630408 · Cited by 1,197
The Rhesus Monkey Brain in Stereotaxic Coordinates
Paxinos, G., Huang, X., & Toga, A. W. (1999) · Research Online (University of Wollongong) · Cited by 1,070
Neural Responses to Taxation and Voluntary Giving Reveal Motives for Charitable Donations
Harbaugh, W. T., Mayr, U., & Burghart, D. R. (2007) · Science · doi:10.1126/science.1140738 · Cited by 1,046
Medial prefrontal cortex as an action-outcome predictor
Alexander, W. H., & Brown, J. W. (2011) · Nature Neuroscience · doi:10.1038/nn.2921 · Cited by 1,000
Optimal decision making and the anterior cingulate cortex
Kennerley, S. W., Walton, M. E., Behrens, T. E. J., Buckley, M. J., & Rushworth, M. F. S. (2006) · Nature Neuroscience · doi:10.1038/nn1724 · Cited by 948
Uniquely human social cognition
Saxe, R. (2006) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2006.03.001 · Cited by 919
The primate amygdala represents the positive and negative value of visual stimuli during learning
Paton, J. J., Belova, M. A., Morrison, S. E., & Salzman, C. D. (2006) · Nature · doi:10.1038/nature04490 · Cited by 917
Human fronto–mesolimbic networks guide decisions about charitable donation
Moll, J., Krueger, F., Zahn, R., Pardini, M., de Oliveira-Souza, R., & Grafman, J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604475103 · Cited by 900
Cingulate cortex of the rhesus monkey: II. Cortical afferents
Vogt, B. A., & Pandya, D. N. (1987) · Journal of Comparative Neurology · doi:10.1002/cne.902620208 · Cited by 854
A common reference frame for movement plans in the posterior parietal cortex
Cohen, Y. E., & Andersen, R. A. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn873 · Cited by 695
Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC
Jeon, D., Kim, S., Chetana, M., Jo, D., Ruley, H. E., Lin, S.-Y., Rabah, D., Kinet, J.-P., & Shin, H.-S. (2010) · Nature Neuroscience · doi:10.1038/nn.2504 · Cited by 651
A new perspective on the role of the orbitofrontal cortex in adaptive behaviour
Schoenbaum, G., Roesch, M. R., Stalnaker, T. A., & Takahashi, Y. K. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2753 · Cited by 585
Performance monitoring by the anterior cingulate cortex during saccade countermanding
Ito, S., Stuphorn, V., Brown, J. W., & Schall, J. D. (2003) · Science · doi:10.1126/science.1087847 · Cited by 581
Representation of negative motivational value in the primate lateral habenula
Matsumoto, M., & Hikosaka, O. (2009) · Nature Neuroscience · doi:10.1038/nn.2233 · Cited by 547
Hare, T. A., Camerer, C. F., Knoepfle, D. T., O'Doherty, J. P., & Rangel, A. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4089-09.2010 · Cited by 527
Neural correlates of mentalizing-related computations during strategic interactions in humans
Hampton, A. N., Bossaerts, P. L., & O’Doherty, J. P. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711099105 · Cited by 522
Double dissociation of value computations in orbitofrontal and anterior cingulate neurons
Kennerley, S. W., Behrens, T. E. J., & Wallis, J. D. (2011) · Nature Neuroscience · doi:10.1038/nn.2961 · Cited by 485
The Computation of Social Behavior
Behrens, T. E. J., Hunt, L. T., & Rushworth, M. F. S. (2009) · Science · doi:10.1126/science.1169694 · Cited by 407
Neural mechanisms of observational learning
Burke, C. J., Tobler, P. N., Baddeley, M. C., & Schultz, W. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1003111107 · Cited by 356
Conditioning through vicarious instigation.
Berger, S. M. (1962) · Psychological Review · doi:10.1037/h0046466 · Cited by 326
A Role for the Macaque Anterior Cingulate Gyrus in Social Valuation
Rudebeck, P. H., Buckley, M. J., Walton, M. E., & Rushworth, M. F. S. (2006) · Science · doi:10.1126/science.1128197 · Cited by 312
Processing of the incentive for social approval in the ventral striatum during charitable donation
Izuma, K., Saito, D. N., & Sadato, N. (2010) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2009.21228 · Cited by 276
A Key Role for Similarity in Vicarious Reward
Mobbs, D., Yu, R., Meyer, M., Passamonti, L., Seymour, B., Calder, A. J., Schweizer, S., Frith, C. D., & Dalgleish, T. (2009) · Science · doi:10.1126/science.1170539 · Cited by 270
Chang, S. W. C., Barter, J. W., Ebitz, R. B., Watson, K. K., & Platt, M. L. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1114621109 · Cited by 252
Self-citationNeural signals in the monkey ventral striatum related to motivation for juice and cocaine rewards
Bowman, E. M., Aigner, T. G., & Richmond, B. J. (1996) · Journal of Neurophysiology · doi:10.1152/jn.1996.75.3.1061 · Cited by 246
Fictive Reward Signals in the Anterior Cingulate Cortex
Hayden, B. Y., Pearson, J. M., & Platt, M. L. (2009) · Science · doi:10.1126/science.1168488 · Cited by 246
Self-citationShidara, M., Aigner, T. G., & Richmond, B. J. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-07-02613.1998 · Cited by 205
Representation of Others' Action by Neurons in Monkey Medial Frontal Cortex
Yoshida, K., Saito, N., Iriki, A., & Isoda, M. (2011) · Current Biology · doi:10.1016/j.cub.2011.01.004 · Cited by 200
Role of Primate Substantia Nigra Pars Reticulata in Reward-Oriented Saccadic Eye Movement
Sato, M., & Hikosaka, O. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-06-02363.2002 · Cited by 191
Response of Dorsomedial Prefrontal Cortex Predicts Altruistic Behavior
Waytz, A. G., Zaki, J., & Mitchell, J. P. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.6193-11.2012 · Cited by 182
Abe, H., & Lee, D. (2011) · Neuron · doi:10.1016/j.neuron.2011.03.026 · Cited by 174
Modulation of value representation by social context in the primate orbitofrontal cortex
Azzi, J. C. B., Angela Sirigu, B., & Duhamel, J. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1111715109 · Cited by 129
Vicarious reinforcement in rhesus macaques (Macaca Mulatta)
Chang, S. W. C., Winecoff, A. A., & Platt, M. L. (2011) · Frontiers in Neuroscience · doi:10.3389/fnins.2011.00027 · Cited by 124
Monkey Orbitofrontal Cortex Encodes Response Choices Near Feedback Time
Tsujimoto, S., Genovesio, A., & Wise, S. P. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5777-08.2009 · Cited by 98
Cortical mechanisms for reinforcement learning in competitive games
Seo, H., & Lee, D. (2008) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2008.0158 · Cited by 66
A reward prediction error for charitable donations reveals outcome orientation of donators
Kuss, K., Falk, A., Trautner, P., Elger, C. E., Weber, B., & Fliessbach, K. (2013) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsr088 · Cited by 51
Encoding of social state information by neuronal activities in the macaque caudate nucleus
dos Santos, G. S., Nagasaka, Y., Fujii, N., & Nakahara, H. (2011) · Social Neuroscience · doi:10.1080/17470919.2011.578465 · Cited by 25
Effects of reward expectancy on sequential eye movements in monkeys
Sohn, J.-W., & Lee, D. (2006) · Neural Networks · doi:10.1016/j.neunet.2006.04.005 · Cited by 23
Cited by
Sorted by citations
Neuronal Reward and Decision Signals: From Theories to Data
Schultz, W. (2015) · Physiological Reviews · doi:10.1152/physrev.00023.2014 · Cited by 1,126
“Rhesus prefer receiving own reward alone over both animals receiving the same reward, suggesting advantageous inequity seeking (negative , of Equation 23), and they prefer seeing conspecifics receive reward over nobody receiving reward, suggesting disadvantageous inequity seeking (negative $) in this setting (23, 89).”
BackgroundThe neurobiology of rewards and values in social decision making
Ruff, C. C., & Fehr, E. (2014) · Nature reviews. Neuroscience · doi:10.1038/nrn3776 · Cited by 716
The Anterior Cingulate Gyrus and Social Cognition: Tracking the Motivation of Others
Apps, M. A. J., Rushworth, M. F. S., & Chang, S. W. C. (2016) · Neuron · doi:10.1016/j.neuron.2016.04.018 · Cited by 559
“This includes frontal lobe regions linked to reward-guided decision making, such as vmPFC and ACCs, and other brain regions such as TPJ and dmPFC linked to other aspects of social cognition andmeta-representation (Chang et al., 2013a; Lee and Seo, 2016).”
InfluentialSelf-citationThe organization of dorsal frontal cortex in humans and macaques
Sallet, J., Mars, R. B., Noonan, M. P., Neubert, F.-X., Jbabdi, S., O'Reilly, J. X., Filippini, N., Thomas, A. G., & Rushworth, M. F. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.5108-12.2013 · Cited by 416
“They make inferences about what others can see (Flombaum and Santos, 2005) and monitor their actions and their outcomes (Yoshida et al., 2011, 2012; Chang et al., 2013).”
BackgroundDorsal Anterior Cingulate Cortex: A Bottom-Up View
Heilbronner, S. R., & Hayden, B. Y. (2016) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-070815-013952 · Cited by 503
“How about the seldom-examined cingulate gyrus (Chang et al. 2013; Rudebeck et al. 2006a,b)?”
Metadata
- Authors
- Chang, S. W. C., Gariépy, J.-F., & Platt, M. L.
- Affiliations
- Duke University (US)
- Corresponding author
- Chang, Steve W C
- Venue
- Nature Neuroscience
- Published
- 2012-12-23
- Volume
- 16
- Issue
- 2
- Pages
- 243-250
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- PMC
- PMC3557617
- OpenAlex
- W2025969629
- Cited by
- 336
- References
- 53
- Citations by year
- 2026: 19 · 2025: 36 · 2024: 16 · 2023: 24 · 2022: 25 · 2021: 54 · 2020: 18 · 2019: 15 · 2018: 23 · 2017: 21 · 2016: 20 · 2015: 21 · 2014: 20 · 2013: 24
- FWCI
- 10.66
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Canadian Institutes of Health Research (84765)
- National Institute of Mental Health (K99MH099093, MH095894, R00-MH099093, R01MH086712, R01MH095894)
- National Institute of Neurological Disorders and Stroke (T32NS051156)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Primate Behavior and Ecology
- Keywords
- social decision-making, orbitofrontal cortex, anterior cingulate cortex, neural coding, collective experience, autism spectrum disorder, sociopathy
- MeSH terms
- Action Potentials, Analysis of Variance, Animals, Brain Mapping, Decision Making, Gyrus Cinguli, Macaca mulatta, Male, Neurons, Photic Stimulation, Reward, Social Behavior, Prefrontal Cortex
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
