Cancer and the chemokine network

Inflammation and cancer

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Stem cells, cancer, and cancer stem cells

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Inflammation and cancer: back to Virchow?

Balkwill, F., & Mantovani, A. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04046-0 · Cited by 7,746

International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels

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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

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Involvement of chemokine receptors in breast cancer metastasis

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Chemokines

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Tumour-educated macrophages promote tumour progression and metastasis

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Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer

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A multigenic program mediating breast cancer metastasis to bone

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A Role for a CXCR2/Phosphatidylinositol 3-Kinase γ Signaling Axis in Acute and Chronic Vascular Permeability

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Inflammation-Induced Hepatocellular Carcinoma Is Dependent on Ccr5 in Mice

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Physiology and Pharmacology of Plerixafor

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CXCL17 Expression Predicts Poor Prognosis and Correlates with Adverse Immune Infiltration in Hepatocellular Carcinoma

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Importance of CCL2-CCR2A/2B signaling for monocyte migration into spheroids of breast cancer-derived fibroblasts

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Insights into the Role of Follicular Helper T Cells in Autoimmunity

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Macrophage migration inhibitory factor: A key cytokine and therapeutic target in colon cancer

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Tumor Cells Induce LAMP2a Expression in Tumor-Associated Macrophage for Cancer Progression

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The Role of tumor-associated macrophage in tumor progression

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Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with NF-κB activation and oxidative stress

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Tumor-associated macrophage-derived CCL20 enhances the growth and metastasis of pancreatic cancer

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Pathomechanisms: homeostatic chemokines in health, tissue regeneration, and progressive diseases

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Identification of Molecular Distinctions Between Normal Breast-Associated Fibroblasts and Breast Cancer-Associated Fibroblasts

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One microenvironment does not fit all: heterogeneity beyond cancer cells

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Targeting key steps in metastatic tumour progression

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CXCR4 antibody treatment suppresses metastatic spread to the lung of intratibial human osteosarcoma xenografts in mice

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Identification of immune-related biomarkers associated with tumorigenesis and prognosis in cutaneous melanoma patients

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Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment

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Control of Receptor Internalization, Signaling Level, and Precise Arrival at the Target in Guided Cell Migration

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CXCR4/CXCL12 Participate in Extravasation of Metastasizing Breast Cancer Cells within the Liver in a Rat Model

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Stoma cell-derived factor-1 overexpression induces gastric dysplasia through expansion of stromal myofibroblasts and epithelial progenitors

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The Human Herpes Virus 8-Encoded Chemokine Receptor Is Required for Angioproliferation in a Murine Model of Kaposi’s Sarcoma

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Targeting CXCR4 with CTCE-9908 inhibits prostate tumor metastasis

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Staphylococcal Superantigen-like 10 Inhibits CXCL12-Induced Human Tumor Cell Migration

Walenkamp, A., Boer, I. G. J., Bestebroer, J., Rozeveld, D., Timmer‐Bosscha, H., Hemrika, W., van Strijp, J. A. G., & de Haas, C. J. C. (2009) · Neoplasia · doi:10.1593/neo.81508 · Cited by 72

Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma

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Decrease in mast cells in oral squamous cell carcinoma: Possible failure in the migration of these cells

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An antagonist of the chemokine receptor CXCR4 induces mitotic catastrophe in ovarian cancer cells

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Human antigen R-regulated CCL20 contributes to osteolytic breast cancer bone metastasis

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Human gastric cancer development with TNF-α-inducing protein secreted from Helicobacter pylori

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Role of CXC group chemokines in lung cancer development and progression

Špaks, A. (2017) · Journal of Thoracic Disease · doi:10.21037/jtd.2017.03.61 · Cited by 71

Revisiting the impact of lifestyle on colorectal cancer risk in a gender perspective

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Macrophages and the hypoxic tumour microenvironment

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A systematic approach to increase the efficiency of membrane protein production in cell-free expression systems

Haberstock, S., Roos, C., Hoevels, Y., Dötsch, V., Schnapp, G., Pautsch, A., & Bernhard, F. (2012) · Protein Expression and Purification · doi:10.1016/j.pep.2012.01.018 · Cited by 71

Antitumor Effect after Radiofrequency Ablation of Murine Hepatoma Is Augmented by an Active Variant of CC Chemokine Ligand 3/Macrophage Inflammatory Protein-1α

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Human glioblastoma tumours and neural cancer stem cells express the chemokine CX3CL1 and its receptor CX3CR1

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Vascular Adhesion Protein-1 Enhances Tumor Growth by Supporting Recruitment of Gr-1+CD11b+ Myeloid Cells into Tumors

Marttila‐Ichihara, F., Auvinen, K., Elima, K., Jalkanen, S., & Salmi, M. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-1205 · Cited by 71

Obesity induced rapid melanoma progression is reversed by orlistat treatment and dietary intervention: Role of adipokines

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CXCL1 stimulates migration and invasion in ER‑negative breast cancer cells via activation of the ERK/MMP2/9 signaling axis

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CCR7 Mediates Inflammation-Associated Tumor Progression

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Leukocytes, inflammation, and angiogenesis in cancer: fatal attractions

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Fractalkine (CX3CL1)– and Interleukin-2–Enriched Neuroblastoma Microenvironment Induces Eradication of Metastases Mediated by T Cells and Natural Killer Cells

Zeng, Y., Huebener, N., Fest, S., Weixler, S., Schroeder, U., Gaedicke, G., Xiang, R., Schramm, A. R., Eggert, A., Reisfeld, R. A., et al. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-3041 · Cited by 70

Estrogen receptor α in cancer associated fibroblasts suppresses prostate cancer invasion via reducing CCL5, IL6 and macrophage infiltration in the tumor microenvironment

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GATA Factor-Dependent Positive-Feedback Circuit in Acute Myeloid Leukemia Cells

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Sesamin Inhibits Macrophage-Induced Vascular Endothelial Growth Factor and Matrix Metalloproteinase-9 Expression and Proangiogenic Activity in Breast Cancer Cells

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Chemokine Receptor Expression in Cutaneous T cell and NK/T-cell Lymphomas: Immunohistochemical Staining and In Vitro Chemotactic Assay

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CXCR6 is expressed in human prostate cancer in vivo and is involved in the in vitro invasion of PC3 and LNCap cells

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The role of the CXCL12-CXCR4/CXCR7 axis in the progression and metastasis of bone sarcomas (Review)

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SPARC mediates metastatic cooperation between CSC and non-CSC prostate cancer cell subpopulations

Mateo, F., Meca‐Cortés, Ó., Celià-Terrassa, T., Fernández, Y., Abasolo, I., Sánchez‐Cid, L., Bermudo, R., Sagasta, A., Rodríguez‐Carunchio, L., Pons, M., et al. (2014) · Molecular Cancer · doi:10.1186/1476-4598-13-237 · Cited by 69

Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells

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CCL5-deficiency enhances intratumoral infiltration of CD8+ T cells in colorectal cancer

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Inhibition of inflammatory CCR2 signaling promotes aged muscle regeneration and strength recovery after injury

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CXCL5 as Regulator of Neutrophil Function in Cutaneous Melanoma

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An NF-κB gene expression signature contributes to Kaposi's sarcoma virus vGPCR-induced direct and paracrine neoplasia

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Clinical opportunities and challenges in targeting tumour dormancy

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CC Chemokine Receptor 5: The Interface of Host Immunity and Cancer

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Macrophages, Inflammation, and Tumor Suppressors: ARF, a New Player in the Game

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New insights into perineural invasion of pancreatic cancer: More than pain

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Galectin-1-driven upregulation of SDF-1 in pancreatic stellate cells promotes pancreatic cancer metastasis

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Role of G12 proteins in oncogenesis and metastasis

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Epidermal growth factor promotes breast cancer cell chemotaxis in CXCL12 gradients

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Cell invasion through basement membranes: an anchor of understanding

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Overexpression of E-cadherin on Melanoma Cells Inhibits Chemokine-promoted Invasion Involving p190RhoGAP/p120ctn-dependent Inactivation of RhoA

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Simultaneous CXCL12 and ESR1 CpG island hypermethylation correlates with poor prognosis in sporadic breast cancer

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Different contributions of chemokine N‐terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3

Szpakowska, M., Nevins, A. M., Meyrath, M., Rhainds, D., D’huys, T., Guité‐Vinet, F., Dupuis, N., Gauthier, P., Counson, M., Kleist, A. B., et al. (2017) · British Journal of Pharmacology · doi:10.1111/bph.14132 · Cited by 66

Biologie de la métastase

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Th17 cells regulate the production of CXCL1 in breast cancer

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CXCL8 Signaling in the Tumor Microenvironment

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Cytokeratin and Vimentin Expression in Breast Cancer

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Identification of the Chemokine CX3CL1 as a New Regulator of Malignant Cell Proliferation in Epithelial Ovarian Cancer

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Wound Healing after Trauma May Predispose to Lung Cancer Metastasis

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Discovery of Tetrahydroisoquinoline-Based CXCR4 Antagonists

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The structural network of inflammation and cancer: Merits and challenges

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Lymphoma microenvironment: culprit or innocent?

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Characterization and clinical relevance of circulating and biopsy-derived endothelial progenitor cells in lymphoma patients

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FDG-PET imaging in hematological malignancies

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Knockdown of long non-coding RNA H19 inhibits multiple myeloma cell growth via NF-κB pathway

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Chemokine expression profile of freshly isolated human glioblastoma-associated macrophages/microglia

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Influence of Magnetic Fields on Magneto-Aerotaxis

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Impact of CD68/(CD3+CD20) Ratio at the Invasive Front of Primary Tumors on Distant Metastasis Development in Breast Cancer

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