Single-cell analysis tools for drug discovery and development

Hallmarks of Cancer: The Next Generation

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

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Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

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Microenvironmental regulation of tumor progression and metastasis

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

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Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets.

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The Clonal Evolution of Tumor Cell Populations: Acquired genetic lability permits stepwise selection of variant sublines and underlies tumor progression.

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Stochastic Gene Expression in a Single Cell

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Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

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The Somatic Genomic Landscape of Glioblastoma

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Neoantigens in cancer immunotherapy

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Full-length RNA-seq from single cells using Smart-seq2

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mRNA-Seq whole-transcriptome analysis of a single cell

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Enhancement of Antitumor Immunity by CTLA-4 Blockade

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Phenotypic Analysis of Antigen-Specific T Lymphocytes

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Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells

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Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

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Discovery and saturation analysis of cancer genes across 21 tumour types

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Spatially resolved, highly multiplexed RNA profiling in single cells

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Bacterial Persistence as a Phenotypic Switch

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Influence of tumour micro-environment heterogeneity on therapeutic response

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Tumour evolution inferred by single-cell sequencing

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Adoptive cell transfer as personalized immunotherapy for human cancer

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Tumour heterogeneity and cancer cell plasticity

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Stochasticity in gene expression: from theories to phenotypes

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Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

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Reducing the Effects of PCR Amplification and Sequencing Artifacts on 16S rRNA-Based Studies

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Cancer immunotherapy via dendritic cells

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Cancer Immunotherapy

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Targeted capture and massively parallel sequencing of 12 human exomes

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Bias caused by template annealing in the amplification of mixtures of 16S rRNA genes by PCR

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Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types

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Models, mechanisms and clinical evidence for cancer dormancy

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Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics

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Stability and Diversity of Ecosystems

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Adoptive cell transfer: a clinical path to effective cancer immunotherapy

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viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

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Bias in template-to-product ratios in multitemplate PCR

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Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells

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Single-cell analysis and sorting using droplet-based microfluidics

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Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

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Selected reaction monitoring–based proteomics: workflows, potential, pitfalls and future directions

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Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

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Target-enrichment strategies for next-generation sequencing

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Tumour heterogeneity in the clinic

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Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells

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Quantitative single-cell RNA-seq with unique molecular identifiers

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Single-cell sequencing-based technologies will revolutionize whole-organism science

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Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy

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Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a Single Human Cell

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Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

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Multiplexed ion beam imaging of human breast tumors

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Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

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Proteomics by Mass Spectrometry: Approaches, Advances, and Applications

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Rapid Amplification of Plasmid and Phage DNA Using Phi29 DNA Polymerase and Multiply-Primed Rolling Circle AmplificationPreprint

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Droplet microfluidic technology for single-cell high-throughput screening

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A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells

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Droplet microfluidics for high-throughput biological assays

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Seventeen-colour flow cytometry: unravelling the immune system

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Counting absolute numbers of molecules using unique molecular identifiers

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Single-cell in situ RNA profiling by sequential hybridization

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Accounting for technical noise in single-cell RNA-seq experiments

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Analysis of gene expression in single live neurons.

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Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing

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Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex

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Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection

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Toll-like Receptors on Hematopoietic Progenitor Cells Stimulate Innate Immune System Replenishment

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Single-cell identification in microbial communities by improved fluorescence in situ hybridization techniques

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Patch Clamp Techniques for Studying Ionic Channels in Excitable Membranes

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Tumor Exome Analysis Reveals Neoantigen-Specific T-Cell Reactivity in an Ipilimumab-Responsive Melanoma

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Single-cell NF-κB dynamics reveal digital activation and analogue information processing

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Validation of noise models for single-cell transcriptomics

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Single-cell dissection of transcriptional heterogeneity in human colon tumors

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Quantitative assessment of single-cell RNA-sequencing methods

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Genome-wide in situ exon capture for selective resequencing

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Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA

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Single Cell Profiling of Potentiated Phospho-Protein Networks in Cancer Cells

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Single-Cell Exome Sequencing Reveals Single-Nucleotide Mutation Characteristics of a Kidney Tumor

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Epidermal growth factor receptor and Ink4a/Arf

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Stochasticity and Cell Fate

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PCR-Induced Sequence Artifacts and Bias: Insights from Comparison of Two 16S rRNA Clone Libraries Constructed from the Same Sample

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Paths to stemness: building the ultimate antitumour T cell

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The History and Future of the Fluorescence Activated Cell Sorter and Flow Cytometry: A View from Stanford

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Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response

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Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastomaPreprint

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Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators

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Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

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Single-Cell Exome Sequencing and Monoclonal Evolution of a JAK2-Negative Myeloproliferative Neoplasm

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Single Cell Profiling of Circulating Tumor Cells: Transcriptional Heterogeneity and Diversity from Breast Cancer Cell Lines

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